JP5523467B2 - 炭酸カルシウム錠剤の改善された溶解安定性 - Google Patents

炭酸カルシウム錠剤の改善された溶解安定性 Download PDF

Info

Publication number
JP5523467B2
JP5523467B2 JP2011535926A JP2011535926A JP5523467B2 JP 5523467 B2 JP5523467 B2 JP 5523467B2 JP 2011535926 A JP2011535926 A JP 2011535926A JP 2011535926 A JP2011535926 A JP 2011535926A JP 5523467 B2 JP5523467 B2 JP 5523467B2
Authority
JP
Japan
Prior art keywords
weight
calcium carbonate
calcium
tablet
magnesium stearate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2011535926A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012508706A (ja
JP2012508706A5 (https=
Inventor
モー オルセン，ペダー
エゴン バーテルセン，ポール
ティステッド，トーマス
ラヴン アーゲ，ヘンリク
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda AS
Original Assignee
Takeda Nycomed AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Nycomed AS filed Critical Takeda Nycomed AS
Publication of JP2012508706A publication Critical patent/JP2012508706A/ja
Publication of JP2012508706A5 publication Critical patent/JP2012508706A5/ja
Application granted granted Critical
Publication of JP5523467B2 publication Critical patent/JP5523467B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2011535926A 2008-11-17 2009-11-17 炭酸カルシウム錠剤の改善された溶解安定性 Expired - Fee Related JP5523467B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08169264.2 2008-11-17
EP08169264 2008-11-17
PCT/EP2009/008157 WO2010054845A1 (en) 2008-11-17 2009-11-17 Improved dissolution stability of calcium carbonate tablets

Publications (3)

Publication Number Publication Date
JP2012508706A JP2012508706A (ja) 2012-04-12
JP2012508706A5 JP2012508706A5 (https=) 2012-12-27
JP5523467B2 true JP5523467B2 (ja) 2014-06-18

Family

ID=40456895

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011535926A Expired - Fee Related JP5523467B2 (ja) 2008-11-17 2009-11-17 炭酸カルシウム錠剤の改善された溶解安定性

Country Status (22)

Country Link
US (2) US9101565B2 (https=)
EP (1) EP2358374B1 (https=)
JP (1) JP5523467B2 (https=)
KR (1) KR101807318B1 (https=)
CN (1) CN102215847B (https=)
AU (1) AU2009315917B2 (https=)
BR (1) BRPI0921599B8 (https=)
CA (1) CA2742449C (https=)
CY (1) CY1114885T1 (https=)
DK (1) DK2358374T3 (https=)
EA (1) EA021707B1 (https=)
ES (1) ES2437851T3 (https=)
HR (1) HRP20131084T1 (https=)
IL (1) IL212442A (https=)
MX (1) MX2011004744A (https=)
NZ (1) NZ592528A (https=)
PL (1) PL2358374T3 (https=)
PT (1) PT2358374E (https=)
SI (1) SI2358374T1 (https=)
SM (1) SMT201400014B (https=)
WO (1) WO2010054845A1 (https=)
ZA (1) ZA201103421B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ592528A (en) 2008-11-17 2013-05-31 Nycomed Pharma As Improved dissolution stability of calcium carbonate tablets
WO2011151018A2 (en) 2010-06-01 2011-12-08 Cargill, Incorporated Orodispersible tablets of erythritol and isomalt
EP3260114A1 (en) 2016-06-21 2017-12-27 Omya International AG Method for the production of a dosage form
CN107281216B (zh) * 2017-06-16 2020-05-05 北京济美堂医药研究有限公司 含钙化合物的药物制剂
CN110575440A (zh) * 2018-06-08 2019-12-17 北京新领先医药科技发展有限公司 一种碳酸钙药物组合物的制备方法
MX2022000267A (es) 2019-07-05 2022-02-03 Tecnimede Sociedade Tecnico Medicinal Sa Composiciones comprimidas de macitentan, metodos y usos de las mismas.
JP7774867B2 (ja) * 2021-10-04 2025-11-25 備前化成株式会社 食品錠剤の製造方法
US20260042979A1 (en) * 2022-08-04 2026-02-12 Symrise Ag Process for the Preparation of a Powder or of a Pastille
KR102675165B1 (ko) * 2023-02-20 2024-06-13 동아제약 주식회사 필름 코팅용 조성물 및 이를 포함하는 필름 코팅액

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115553A (en) * 1973-12-10 1978-09-19 Armour Pharmaceutical Company Antacid tablets
US5204115A (en) 1990-12-12 1993-04-20 Suomen Xyrofin Oy Directly compressible xylitol and method
JP2995226B2 (ja) 1992-03-03 1999-12-27 日本ワイスレダリー株式会社 カルシウム含有チユアブル錠
US5405623A (en) 1993-09-22 1995-04-11 Wm. Wrigley Jr. Company Chewing gum compositions and methods for manufacturing same
DE4427137B4 (de) 1993-10-07 2007-08-23 Degussa Gmbh Fällungskieselsäure
US6716454B2 (en) * 1994-09-23 2004-04-06 Laboratorie Innothera, Société Anonyme Therapeutic combination of vitamin and calcium in unitary galenic tablet form, a method of obtaining it, and the use thereof
FR2724844B1 (fr) 1994-09-23 1997-01-24 Innothera Lab Sa Association therapeutique vitamino-calcique, son procede d'obtention et son utilisation
US5846506A (en) 1994-10-07 1998-12-08 Degussa Aktiengesellschaft Precipitated silicas
DE19617487A1 (de) 1996-05-02 1997-11-06 Merck Patent Gmbh Geschmacksverbesserung von Arzneimittelwirkstoffen
DK0914818T3 (da) 1996-06-14 2005-07-04 Kyowa Hakko Kogyo Kk Intraoralt hurtigt desintegrerbar tablet
FR2762217B1 (fr) 1997-04-16 2000-09-29 Besins Iscovesco Lab Preparation solide vitamino-calcique, son procede d'obtention et son utilisation
ITFI970184A1 (it) 1997-07-30 1999-01-30 Menarini Farma Ind Composizioni farmaceutiche contenenti vitamina d e calcio,loro preparazione ed uso terapeutico
GB9825033D0 (en) 1998-11-13 1999-01-13 Nycomed Pharma As Process
JP2001316249A (ja) 2000-05-11 2001-11-13 Lion Corp 錠剤型医薬組成物
WO2002070013A1 (en) 2001-03-06 2002-09-12 Kyowa Hakko Kogyo Co., Ltd. Utilization of spray-dried powder containing sugar alcohol
JPWO2002069934A1 (ja) 2001-03-06 2004-07-02 協和醗酵工業株式会社 口腔内速崩壊性製剤
BR0211117A (pt) * 2001-07-16 2004-06-22 Astrazeneca Ab Tablete multiparticulado, processo para a manufatura e uso do mesmo, e, método e tratamento de distúrbios gastrointestinais
ES2192136B1 (es) 2002-01-04 2005-03-16 Italfarmaco, S.A. Composiciones farmaceuticas para el tratamiento o prevencion de la osteoporosis.
DE20216314U1 (de) 2002-10-22 2003-12-04 Dhw Deutsche Hydrierwerke Gmbh Rodleben Sprühgetrockneter Xylitol und aus diesem hergestellte Komprimate
MXPA06013608A (es) * 2004-05-24 2007-04-26 Nycomed Pharma As Particulado que comprende un compuesto que contiene calcio y un alcohol de azucar.
JP4996458B2 (ja) * 2004-06-01 2012-08-08 ニコメド ファーマ エイエス 活性物質としてカルシウム含有化合物を含み、咀嚼し、舐め、飲み込むことのできる錠剤
DE602006001295D1 (de) * 2005-02-03 2008-07-03 Nycomed Pharma As Schmelzgranulation einer zusammensetzung mit einer calziumhaltigen verbindung
DE602006016641D1 (de) 2005-12-07 2010-10-14 Nycomed Danmark Aps Vorkompaktierte calciumhaltige zusammensetzungen
UA95093C2 (uk) 2005-12-07 2011-07-11 Нікомед Фарма Ас Спосіб одержання кальцієвмісної сполуки
CN101584153B (zh) 2007-01-16 2012-10-10 皇家飞利浦电子股份有限公司 混合型定向终端的设备发现
NZ592528A (en) 2008-11-17 2013-05-31 Nycomed Pharma As Improved dissolution stability of calcium carbonate tablets

Also Published As

Publication number Publication date
CA2742449C (en) 2018-04-24
WO2010054845A1 (en) 2010-05-20
SMT201400014B (it) 2014-03-07
HK1162354A1 (en) 2012-08-31
AU2009315917B2 (en) 2014-11-20
AU2009315917A1 (en) 2010-05-20
DK2358374T3 (da) 2013-11-11
US9999634B2 (en) 2018-06-19
US9101565B2 (en) 2015-08-11
NZ592528A (en) 2013-05-31
EP2358374A1 (en) 2011-08-24
KR101807318B1 (ko) 2018-01-10
US20160022732A1 (en) 2016-01-28
CA2742449A1 (en) 2010-05-20
JP2012508706A (ja) 2012-04-12
IL212442A (en) 2015-10-29
KR20110086592A (ko) 2011-07-28
EA201170695A1 (ru) 2011-12-30
CY1114885T1 (el) 2016-12-14
BRPI0921599B1 (pt) 2020-08-18
BRPI0921599B8 (pt) 2021-05-25
PT2358374E (pt) 2013-12-09
CN102215847B (zh) 2014-07-16
ES2437851T3 (es) 2014-01-14
ZA201103421B (en) 2012-10-31
MX2011004744A (es) 2011-05-30
EA021707B1 (ru) 2015-08-31
HRP20131084T1 (hr) 2013-12-20
CN102215847A (zh) 2011-10-12
US20110287098A1 (en) 2011-11-24
BRPI0921599A2 (pt) 2016-02-10
IL212442A0 (en) 2011-06-30
SI2358374T1 (sl) 2014-01-31
EP2358374B1 (en) 2013-09-18
PL2358374T3 (pl) 2014-03-31

Similar Documents

Publication Publication Date Title
US10357460B2 (en) Particulate comprising a calcium-containing compound and a sugar alcohol
JP5523467B2 (ja) 炭酸カルシウム錠剤の改善された溶解安定性
US8808735B2 (en) Fast wet-massing method for the preparation of calcium-containing compositions
JP2014051506A (ja) 予備圧縮されたカルシウム含有組成物
HK1162354B (en) Improved dissolution stability of calcium carbonate tablets
HK1103009B (en) Particulate comprising a calcium-containing compound and a sugar alcohol

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20121109

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20121109

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20131217

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20131220

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140311

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20140401

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20140408

R150 Certificate of patent or registration of utility model

Ref document number: 5523467

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

S533 Written request for registration of change of name

Free format text: JAPANESE INTERMEDIATE CODE: R313533

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees