JP5507464B2 - ベンジルフェニルシクロヘキサン誘導体およびその使用方法 - Google Patents

ベンジルフェニルシクロヘキサン誘導体およびその使用方法 Download PDF

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Publication number
JP5507464B2
JP5507464B2 JP2010538165A JP2010538165A JP5507464B2 JP 5507464 B2 JP5507464 B2 JP 5507464B2 JP 2010538165 A JP2010538165 A JP 2010538165A JP 2010538165 A JP2010538165 A JP 2010538165A JP 5507464 B2 JP5507464 B2 JP 5507464B2
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chloro
phenyl
alkyl
hydroxymethyl
compound
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Japanese (ja)
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JP2011506469A (ja
JP2011506469A5 (enExample
Inventor
ユアンウェイ・チェン
ペン・クン
チャン・リリ
エルブイ・ビンフア
スー・バイフア
ドン・ジアジア
ドゥ・ジヤン
フェン・ヤン
スー・ゲ
バサンサクマール・ラジャッパン
ブライアン・シード
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Theracos Inc
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Theracos Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04—Carbocyclic radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
JP2010538165A 2007-12-13 2008-12-11 ベンジルフェニルシクロヘキサン誘導体およびその使用方法 Expired - Fee Related JP5507464B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1351707P 2007-12-13 2007-12-13
US61/013,517 2007-12-13
PCT/US2008/086472 WO2009076550A1 (en) 2007-12-13 2008-12-11 Benzylphenyl cyclohexane derivatives and methods of use

Publications (3)

Publication Number Publication Date
JP2011506469A JP2011506469A (ja) 2011-03-03
JP2011506469A5 JP2011506469A5 (enExample) 2012-02-02
JP5507464B2 true JP5507464B2 (ja) 2014-05-28

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JP2010538165A Expired - Fee Related JP5507464B2 (ja) 2007-12-13 2008-12-11 ベンジルフェニルシクロヘキサン誘導体およびその使用方法

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Country Link
US (1) US8129434B2 (enExample)
EP (1) EP2230907B1 (enExample)
JP (1) JP5507464B2 (enExample)
KR (1) KR101567969B1 (enExample)
CN (1) CN101938902B (enExample)
AR (2) AR071268A1 (enExample)
AU (1) AU2008335080B2 (enExample)
BR (1) BRPI0819930A2 (enExample)
CA (1) CA2707909C (enExample)
IL (1) IL206234A0 (enExample)
NZ (1) NZ586639A (enExample)
RU (1) RU2505521C2 (enExample)
TW (1) TWI426081B (enExample)
UA (1) UA101004C2 (enExample)
WO (1) WO2009076550A1 (enExample)
ZA (1) ZA201004400B (enExample)

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CN104909997B (zh) * 2011-05-26 2017-04-12 Tf化学公司 芳基、杂芳基、o‑芳基和o‑杂芳基碳环糖家族
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WO2013045413A1 (en) 2011-09-27 2013-04-04 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
CN103570671B (zh) * 2012-09-26 2016-03-30 上海天慈生物谷生物工程有限公司 一种降糖化合物及其制法和应用
WO2015051484A1 (en) 2013-10-12 2015-04-16 Theracos, Inc. Preparation of hydroxy-benzylbenzene derivatives
PL3082829T3 (pl) 2013-12-17 2021-09-06 Boehringer Ingelheim Vetmedica Gmbh Inhibitory sglt2 do leczenia zaburzeń metabolicznych u zwierząt kotowatych
US10759729B2 (en) * 2016-11-07 2020-09-01 The Chinese University Of Hong Kong Compounds for treating diabetes
CN116785268A (zh) * 2022-03-14 2023-09-22 江苏万邦生化医药集团有限责任公司 一种sglt-2抑制剂的药物组合物

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Also Published As

Publication number Publication date
CA2707909C (en) 2016-10-18
WO2009076550A1 (en) 2009-06-18
TW200932755A (en) 2009-08-01
AR071268A1 (es) 2010-06-09
KR20100098690A (ko) 2010-09-08
EP2230907A1 (en) 2010-09-29
UA101004C2 (en) 2013-02-25
AU2008335080B2 (en) 2014-06-05
RU2505521C2 (ru) 2014-01-27
JP2011506469A (ja) 2011-03-03
CA2707909A1 (en) 2009-06-18
RU2010128940A (ru) 2012-01-20
EP2230907A4 (en) 2015-04-08
US8129434B2 (en) 2012-03-06
KR101567969B1 (ko) 2015-11-10
AU2008335080A1 (en) 2009-06-18
IL206234A0 (en) 2010-12-30
TWI426081B (zh) 2014-02-11
CN101938902A (zh) 2011-01-05
BRPI0819930A2 (pt) 2016-05-17
US20090156516A1 (en) 2009-06-18
EP2230907B1 (en) 2018-05-09
CN101938902B (zh) 2014-07-02
AR113211A2 (es) 2020-02-19
NZ586639A (en) 2011-06-30
ZA201004400B (en) 2014-10-29

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