JP5474559B2 - 膵島細胞の長期培養のための骨髄細胞の使用 - Google Patents

膵島細胞の長期培養のための骨髄細胞の使用 Download PDF

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JP5474559B2
JP5474559B2 JP2009538403A JP2009538403A JP5474559B2 JP 5474559 B2 JP5474559 B2 JP 5474559B2 JP 2009538403 A JP2009538403 A JP 2009538403A JP 2009538403 A JP2009538403 A JP 2009538403A JP 5474559 B2 JP5474559 B2 JP 5474559B2
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cells
islet
bone marrow
cell
culture
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JP2010509936A5 (enExample
JP2010509936A (ja
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ルガング ルオ,
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ロジャー・ウィリアムズ・ホスピタル
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0676Pancreatic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1394Bone marrow stromal cells; whole marrow

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  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
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  • Diabetes (AREA)
  • Microbiology (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
JP2009538403A 2006-11-21 2007-11-20 膵島細胞の長期培養のための骨髄細胞の使用 Expired - Fee Related JP5474559B2 (ja)

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Application Number Priority Date Filing Date Title
US86063706P 2006-11-21 2006-11-21
US60/860,637 2006-11-21
PCT/US2007/024258 WO2008063640A2 (en) 2006-11-21 2007-11-20 Use of bone marrow cells for long term culture of pancreatic islet cells

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JP2010509936A JP2010509936A (ja) 2010-04-02
JP2010509936A5 JP2010509936A5 (enExample) 2011-01-20
JP5474559B2 true JP5474559B2 (ja) 2014-04-16

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JP2009538403A Expired - Fee Related JP5474559B2 (ja) 2006-11-21 2007-11-20 膵島細胞の長期培養のための骨髄細胞の使用

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US (1) US20100143306A1 (enExample)
EP (1) EP2092057B1 (enExample)
JP (1) JP5474559B2 (enExample)
CN (2) CN103992982A (enExample)
AU (1) AU2007321983B2 (enExample)
CA (1) CA2670289A1 (enExample)
WO (1) WO2008063640A2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102803475B (zh) 2010-03-17 2015-04-22 国立大学法人京都大学 通过胰脏衍生的非内分泌上皮细胞和血管内皮细胞的组织复合物培养胰岛样组织的方法
CA3104901A1 (en) * 2018-06-25 2020-01-02 Imagine Pharma, Llc Compositions and methods for propagating insulin-producing islet cells and therapeutic uses thereof
EP4288487A4 (en) * 2021-02-03 2024-12-11 Symbiocelltech, LLC CELL AGGREGATES COMPRISING STEM CELLS AND ISLETS OF LANGERHANS, METHODS OF PREPARATION, AND TREATMENT OF DIABETES MELLITUS WITH THEM

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001647A (en) * 1994-04-28 1999-12-14 Ixion Biotechnology, Inc. In vitro growth of functional islets of Langerhans and in vivo uses thereof
JPWO2003087349A1 (ja) * 2002-04-17 2005-08-18 大塚製薬株式会社 間葉系細胞から膵β細胞を形成する方法

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CN103992982A (zh) 2014-08-20
AU2007321983A1 (en) 2008-05-29
WO2008063640A3 (en) 2008-12-18
WO2008063640A2 (en) 2008-05-29
EP2092057A2 (en) 2009-08-26
EP2092057B1 (en) 2014-10-15
AU2007321983B2 (en) 2014-05-29
EP2092057A4 (en) 2011-04-20
CA2670289A1 (en) 2008-05-29
CN101652470A (zh) 2010-02-17
US20100143306A1 (en) 2010-06-10
JP2010509936A (ja) 2010-04-02

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