AU2007321983B2 - Use of bone marrow cells for long term culture of pancreatic islet cells - Google Patents

Use of bone marrow cells for long term culture of pancreatic islet cells Download PDF

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Publication number
AU2007321983B2
AU2007321983B2 AU2007321983A AU2007321983A AU2007321983B2 AU 2007321983 B2 AU2007321983 B2 AU 2007321983B2 AU 2007321983 A AU2007321983 A AU 2007321983A AU 2007321983 A AU2007321983 A AU 2007321983A AU 2007321983 B2 AU2007321983 B2 AU 2007321983B2
Authority
AU
Australia
Prior art keywords
islet
cell
cells
bone marrow
culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2007321983A
Other languages
English (en)
Other versions
AU2007321983A1 (en
Inventor
Luguang Luo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roger Williams Medical Center
Original Assignee
Roger Williams Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roger Williams Medical Center filed Critical Roger Williams Medical Center
Publication of AU2007321983A1 publication Critical patent/AU2007321983A1/en
Application granted granted Critical
Publication of AU2007321983B2 publication Critical patent/AU2007321983B2/en
Priority to AU2014218470A priority Critical patent/AU2014218470A1/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1394—Bone marrow stromal cells; whole marrow

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
AU2007321983A 2006-11-21 2007-11-20 Use of bone marrow cells for long term culture of pancreatic islet cells Ceased AU2007321983B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2014218470A AU2014218470A1 (en) 2006-11-21 2014-08-29 Use of bone marrow cells for long term culture of pancreatic islet cells.

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86063706P 2006-11-21 2006-11-21
US60/860,637 2006-11-21
PCT/US2007/024258 WO2008063640A2 (en) 2006-11-21 2007-11-20 Use of bone marrow cells for long term culture of pancreatic islet cells

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2014218470A Division AU2014218470A1 (en) 2006-11-21 2014-08-29 Use of bone marrow cells for long term culture of pancreatic islet cells.

Publications (2)

Publication Number Publication Date
AU2007321983A1 AU2007321983A1 (en) 2008-05-29
AU2007321983B2 true AU2007321983B2 (en) 2014-05-29

Family

ID=39430369

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007321983A Ceased AU2007321983B2 (en) 2006-11-21 2007-11-20 Use of bone marrow cells for long term culture of pancreatic islet cells

Country Status (7)

Country Link
US (1) US20100143306A1 (enExample)
EP (1) EP2092057B1 (enExample)
JP (1) JP5474559B2 (enExample)
CN (2) CN103992982A (enExample)
AU (1) AU2007321983B2 (enExample)
CA (1) CA2670289A1 (enExample)
WO (1) WO2008063640A2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013521797A (ja) 2010-03-17 2013-06-13 国立大学法人京都大学 膵由来非内分泌上皮細胞と血管内皮細胞との組織複合体による膵島様組織の培養法
MX2020014242A (es) * 2018-06-25 2021-05-27 Imagine Pharma Llc Composiciones y métodos para propagar las células de islotes productoras de insulina y usos terapéuticos de las mismas.
US20240084261A1 (en) * 2021-02-03 2024-03-14 Symbiocelltech, Llc Cell Clusters Comprising Stem and Islet Cells, Methods of Making, and Treatment of Diabetes Mellitus Therewith

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001647A (en) * 1994-04-28 1999-12-14 Ixion Biotechnology, Inc. In vitro growth of functional islets of Langerhans and in vivo uses thereof
US20050208029A1 (en) * 2002-04-17 2005-09-22 Akihiro Umezawa Method of forming pancreatic beta cells from mesenchymal cells

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Liu, G. et al., Blood. 2003 vol. 102 no. 11 page 338A *

Also Published As

Publication number Publication date
EP2092057A4 (en) 2011-04-20
EP2092057A2 (en) 2009-08-26
CN103992982A (zh) 2014-08-20
JP5474559B2 (ja) 2014-04-16
WO2008063640A2 (en) 2008-05-29
WO2008063640A3 (en) 2008-12-18
EP2092057B1 (en) 2014-10-15
CA2670289A1 (en) 2008-05-29
CN101652470A (zh) 2010-02-17
AU2007321983A1 (en) 2008-05-29
US20100143306A1 (en) 2010-06-10
JP2010509936A (ja) 2010-04-02

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Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired