JP5465815B2 - 関節症治療剤 - Google Patents
関節症治療剤 Download PDFInfo
- Publication number
- JP5465815B2 JP5465815B2 JP2013542900A JP2013542900A JP5465815B2 JP 5465815 B2 JP5465815 B2 JP 5465815B2 JP 2013542900 A JP2013542900 A JP 2013542900A JP 2013542900 A JP2013542900 A JP 2013542900A JP 5465815 B2 JP5465815 B2 JP 5465815B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- phosphatidic acid
- formula
- arthropathy
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013542900A JP5465815B2 (ja) | 2011-11-11 | 2012-10-12 | 関節症治療剤 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011247047 | 2011-11-11 | ||
| JP2011247047 | 2011-11-11 | ||
| JP2013542900A JP5465815B2 (ja) | 2011-11-11 | 2012-10-12 | 関節症治療剤 |
| PCT/JP2012/076478 WO2013069404A1 (ja) | 2011-11-11 | 2012-10-12 | 関節症治療剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP5465815B2 true JP5465815B2 (ja) | 2014-04-09 |
| JPWO2013069404A1 JPWO2013069404A1 (ja) | 2015-04-02 |
Family
ID=48289788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013542900A Active JP5465815B2 (ja) | 2011-11-11 | 2012-10-12 | 関節症治療剤 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9085593B2 (https=) |
| EP (1) | EP2803359B1 (https=) |
| JP (1) | JP5465815B2 (https=) |
| KR (1) | KR101953181B1 (https=) |
| CN (1) | CN103906519B (https=) |
| AU (1) | AU2012337087B2 (https=) |
| BR (1) | BR112014011315B8 (https=) |
| CA (1) | CA2855660C (https=) |
| ES (1) | ES2634008T3 (https=) |
| IN (1) | IN2014CN04222A (https=) |
| MY (1) | MY168931A (https=) |
| PH (1) | PH12014501058B1 (https=) |
| RU (1) | RU2646457C2 (https=) |
| SG (1) | SG11201402226PA (https=) |
| WO (1) | WO2013069404A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022114058A1 (ja) | 2020-11-26 | 2022-06-02 | Ｓａｎｓｈｏ株式会社 | 肺線維症治療剤 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3483169B1 (en) | 2014-08-12 | 2021-05-26 | Otsuka Chemical Co., Ltd. | Crystal of cyclic phosphonic acid sodium salt and method for manufacturing same |
| JP6727596B1 (ja) | 2019-11-22 | 2020-07-22 | 国立大学法人お茶の水女子大学 | カルバリゾホスファチジン酸 |
| JP7566783B2 (ja) | 2019-12-23 | 2024-10-15 | 大塚化学株式会社 | カルバ環状ホスファチジン酸化合物 |
| JP7736256B2 (ja) * | 2020-11-13 | 2025-09-09 | 株式会社マツモト交商 | 環状ホスファチジン酸含有組成物及び美容方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07149772A (ja) * | 1993-11-26 | 1995-06-13 | Sagami Chem Res Center | タンパク質リン酸化酵素ｃの活性促進剤 |
| JP2004010582A (ja) * | 2002-06-11 | 2004-01-15 | Gencom Co | カルバ環状ホスファチジン酸誘導体 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2700350B2 (ja) | 1990-04-20 | 1998-01-21 | 小糸工業株式会社 | 車両感知器 |
| JP3195833B2 (ja) | 1991-09-30 | 2001-08-06 | きみ子 室伏 | 新規生理活性物質及びその製造法 |
| JPH07258278A (ja) | 1994-03-18 | 1995-10-09 | Sagami Chem Res Center | １−Ｏ−アシルグリセロール−２，３−ホスフェート誘導体を有効成分とするＤＮＡポリメラーゼαの阻害剤 |
| JPH0925235A (ja) | 1995-07-13 | 1997-01-28 | Sagami Chem Res Center | １−ｏ−アシルグリセロール−２，３−ホスフェート誘導体を有効成分とするがん転移抑制剤 |
| JP2001178489A (ja) | 1999-12-24 | 2001-07-03 | Kimiko Murofushi | 環状ホスファチジン酸の製造法 |
| JP4815063B2 (ja) * | 2001-04-13 | 2011-11-16 | きみ子 室伏 | 環状ホスファチジン酸を含むグリア細胞の増殖、分化及び／又は生存の促進のための薬剤 |
| JP4836345B2 (ja) * | 2001-04-13 | 2011-12-14 | きみ子 室伏 | 環状ホスファチジン酸誘導体を含む神経細胞の生存促進剤 |
| US20040214799A1 (en) * | 2001-05-21 | 2004-10-28 | Mutsuko Mukai | Cancerous metastasis inhibitors containing carbacyclic phosphatidic acid derivatives |
| RU2240131C1 (ru) * | 2003-04-04 | 2004-11-20 | Аладьев Сергей Иванович | Средство "артровит" для профилактики и лечения артритов и артрозов |
| CA2521189A1 (en) * | 2003-04-11 | 2004-10-28 | Gabor Tigyi | Lysophosphatidic acid analogs and inhibition of neointima formation |
| JP4873352B2 (ja) | 2005-02-16 | 2012-02-08 | シェーリング コーポレイション | Ｃｘｃｒ３アンタゴニスト活性を有する、複素環で置換されたピペラジン |
| EP2098237B1 (en) * | 2006-12-28 | 2012-08-29 | Ochanomizu University | Analgesic agent comprising cyclic phosphatidic acid derivative |
| JP2010189315A (ja) * | 2009-02-18 | 2010-09-02 | Unitika Ltd | 関節軟骨損傷治癒促進剤及びそれを含有する飲食品 |
-
2012
- 2012-10-12 JP JP2013542900A patent/JP5465815B2/ja active Active
- 2012-10-12 MY MYPI2014701211A patent/MY168931A/en unknown
- 2012-10-12 PH PH1/2014/501058A patent/PH12014501058B1/en unknown
- 2012-10-12 IN IN4222CHN2014 patent/IN2014CN04222A/en unknown
- 2012-10-12 AU AU2012337087A patent/AU2012337087B2/en active Active
- 2012-10-12 RU RU2014123690A patent/RU2646457C2/ru active
- 2012-10-12 BR BR112014011315A patent/BR112014011315B8/pt active IP Right Grant
- 2012-10-12 SG SG11201402226PA patent/SG11201402226PA/en unknown
- 2012-10-12 WO PCT/JP2012/076478 patent/WO2013069404A1/ja not_active Ceased
- 2012-10-12 ES ES12847890.6T patent/ES2634008T3/es active Active
- 2012-10-12 US US14/357,089 patent/US9085593B2/en active Active
- 2012-10-12 CN CN201280055135.7A patent/CN103906519B/zh active Active
- 2012-10-12 EP EP12847890.6A patent/EP2803359B1/en active Active
- 2012-10-12 KR KR1020147015608A patent/KR101953181B1/ko active Active
- 2012-10-12 CA CA2855660A patent/CA2855660C/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07149772A (ja) * | 1993-11-26 | 1995-06-13 | Sagami Chem Res Center | タンパク質リン酸化酵素ｃの活性促進剤 |
| JP2004010582A (ja) * | 2002-06-11 | 2004-01-15 | Gencom Co | カルバ環状ホスファチジン酸誘導体 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022114058A1 (ja) | 2020-11-26 | 2022-06-02 | Ｓａｎｓｈｏ株式会社 | 肺線維症治療剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103906519A (zh) | 2014-07-02 |
| BR112014011315A2 (pt) | 2017-05-09 |
| AU2012337087A1 (en) | 2014-06-05 |
| EP2803359A4 (en) | 2015-12-16 |
| BR112014011315B8 (pt) | 2020-09-15 |
| PH12014501058A1 (en) | 2014-06-23 |
| EP2803359B1 (en) | 2017-04-19 |
| NZ624870A (en) | 2016-01-29 |
| US20140309194A1 (en) | 2014-10-16 |
| HK1199406A1 (en) | 2015-07-03 |
| RU2646457C2 (ru) | 2018-03-05 |
| CN103906519B (zh) | 2017-10-10 |
| BR112014011315B1 (pt) | 2020-03-03 |
| IN2014CN04222A (https=) | 2015-07-17 |
| RU2014123690A (ru) | 2015-12-20 |
| CA2855660C (en) | 2019-04-16 |
| EP2803359A1 (en) | 2014-11-19 |
| SG11201402226PA (en) | 2014-10-30 |
| US9085593B2 (en) | 2015-07-21 |
| JPWO2013069404A1 (ja) | 2015-04-02 |
| AU2012337087B2 (en) | 2016-11-17 |
| WO2013069404A1 (ja) | 2013-05-16 |
| CA2855660A1 (en) | 2013-05-16 |
| MY168931A (en) | 2019-01-09 |
| ES2634008T3 (es) | 2017-09-26 |
| KR20140098778A (ko) | 2014-08-08 |
| KR101953181B1 (ko) | 2019-02-28 |
| PH12014501058B1 (en) | 2019-11-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5465815B2 (ja) | 関節症治療剤 | |
| EP1402894B1 (en) | Cancerous metastasis inhibitors containing carbacyclic phosphatidic acid derivatives | |
| US8017597B2 (en) | Analgesic agent comprising cyclic phosphatidic acid derivative | |
| EP4049724A1 (en) | Pharmaceutical composition for protecting cartilage | |
| JP6864899B2 (ja) | 損傷治療剤 | |
| EP3697412B1 (en) | A compound for treating osteoarthritis | |
| JP5747263B2 (ja) | 神経細胞死抑制剤 | |
| HK1199406B (en) | Therapeutic agent for joint diseases | |
| KR20060028630A (ko) | 이노시톨 폴리포스페이트 유도체 및 그의 사용 방법 | |
| WO2020058889A1 (en) | Amino acid derivative of glucosamine stimulating extracellular matrix synthesis and pharmaceutical composition comprising the same | |
| JPH09227386A (ja) | ストレス蛋白質発現増強剤 | |
| NZ624870B2 (en) | Therapeutic agent for arthrosis | |
| WO2022114058A1 (ja) | 肺線維症治療剤 | |
| Herrmanna et al. | Antitumor Activity of Ilmofosine (BM 41.440) in the 3Lewis-Lung Carcinoma Model1 | |
| JP2001064168A (ja) | 変形性関節症治療剤 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20140114 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20140122 |
|
| R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 Ref document number: 5465815 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313114 |
|
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| S531 | Written request for registration of change of domicile |
Free format text: JAPANESE INTERMEDIATE CODE: R313531 |
|
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313117 |
|
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |