JP5452843B2 - 夜間の経口インスリン治療 - Google Patents

夜間の経口インスリン治療 Download PDF

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Publication number
JP5452843B2
JP5452843B2 JP2006500813A JP2006500813A JP5452843B2 JP 5452843 B2 JP5452843 B2 JP 5452843B2 JP 2006500813 A JP2006500813 A JP 2006500813A JP 2006500813 A JP2006500813 A JP 2006500813A JP 5452843 B2 JP5452843 B2 JP 5452843B2
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JP
Japan
Prior art keywords
insulin
use according
oral administration
medicament
delivery
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2006500813A
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English (en)
Japanese (ja)
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JP2006515620A (ja
JP2006515620A5 (enExample
Inventor
マイケル ゴールドバーグ
イーハッド アービット
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Emisphere Technologies Inc
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Emisphere Technologies Inc
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Publication date
Application filed by Emisphere Technologies Inc filed Critical Emisphere Technologies Inc
Publication of JP2006515620A publication Critical patent/JP2006515620A/ja
Publication of JP2006515620A5 publication Critical patent/JP2006515620A5/ja
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Publication of JP5452843B2 publication Critical patent/JP5452843B2/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2006500813A 2003-01-06 2004-01-06 夜間の経口インスリン治療 Expired - Fee Related JP5452843B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US43845103P 2003-01-06 2003-01-06
US43819503P 2003-01-06 2003-01-06
US60/438,195 2003-01-06
US60/438,451 2003-01-06
US47896703P 2003-06-16 2003-06-16
US60/478,967 2003-06-16
PCT/US2004/000273 WO2004062587A2 (en) 2003-01-06 2004-01-06 Night-time oral insulin therapy

Publications (3)

Publication Number Publication Date
JP2006515620A JP2006515620A (ja) 2006-06-01
JP2006515620A5 JP2006515620A5 (enExample) 2007-03-01
JP5452843B2 true JP5452843B2 (ja) 2014-03-26

Family

ID=32719186

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006500813A Expired - Fee Related JP5452843B2 (ja) 2003-01-06 2004-01-06 夜間の経口インスリン治療

Country Status (8)

Country Link
US (1) US7384914B2 (enExample)
EP (1) EP1592438B1 (enExample)
JP (1) JP5452843B2 (enExample)
AU (1) AU2004204727B8 (enExample)
CA (1) CA2511530C (enExample)
ES (1) ES2465496T3 (enExample)
NZ (1) NZ541058A (enExample)
WO (1) WO2004062587A2 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2473340C (en) 2002-02-20 2014-12-09 Eli Lilly And Company Formulations comprising a glp-1 compound and a delivery agent, and uses thereof
AU2004220544B2 (en) * 2003-03-06 2010-06-17 Emisphere Technologies, Inc. Oral insulin therapies and protocol
US20050203001A1 (en) 2004-03-05 2005-09-15 Emisphere Technologies, Inc. Oral insulin therapies and protocol
US20060286129A1 (en) 2003-12-19 2006-12-21 Emisphere Technologies, Inc. Oral GLP-1 formulations
US8273794B2 (en) * 2004-05-14 2012-09-25 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
CN1968699B (zh) 2004-05-19 2010-12-15 爱密斯菲尔科技公司 阿昔洛韦制剂
CA2573856A1 (en) * 2004-08-03 2006-02-16 Emisphere Technologies, Inc. Antidiabetic oral insulin-biguanide combination
CA2591515C (en) 2004-12-29 2010-06-22 Emisphere Technologies, Inc. Pharmaceutical formulations of gallium salts
WO2006076692A1 (en) 2005-01-12 2006-07-20 Emisphere Technologies, Inc. Compositions for buccal delivery of parathyroid hormone
WO2006125763A1 (en) * 2005-05-25 2006-11-30 Novo Nordisk A/S Stabilized polypeptide formulations
EP1888117A1 (en) * 2005-05-25 2008-02-20 Novo Nordisk A/S Stabilized polypeptide formulations
WO2007121318A2 (en) 2006-04-12 2007-10-25 Emisphere Technologies, Inc. Formulations for delivering insulin
WO2007133944A2 (en) 2006-05-09 2007-11-22 Emisphere Technologies, Inc. Topical administration of acyclovir
US9364502B2 (en) 2006-06-28 2016-06-14 Emisphere Technologies, Inc. Gallium nitrate formulations
WO2008132731A2 (en) * 2007-04-26 2008-11-06 Oramed Pharmaceuticals, Inc Methods and compositions for rectal administration of insulin
IL188647A0 (en) * 2008-01-08 2008-11-03 Orina Gribova Adaptable structured drug and supplements administration system (for oral and/or transdermal applications)
CA2734442C (en) 2008-08-18 2016-08-16 Oramed Ltd Methods and compositions for oral administration of proteins
CN105997864A (zh) 2009-07-09 2016-10-12 奥莎迪药品管理有限公司 基质载体组合物、方法及用途
WO2011017346A2 (en) 2009-08-03 2011-02-10 Emisphere Technologies, Inc. Fast-acting naproxen composition with reduced gastrointestinal effects
WO2023286049A1 (en) 2021-07-12 2023-01-19 Zidkiyahu Simenhaus Protein containing bio-active compositions comprising cellulose microparticle carriers

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4863896A (en) 1984-05-03 1989-09-05 Technology Unlimited, Inc. Diabetic control by combined insulin forms
RU2066551C1 (ru) * 1994-03-23 1996-09-20 Институт нефтехимического синтеза РАН Способ получения инсулинсодержащих полимерных гидрогелей
US5780243A (en) * 1996-06-28 1998-07-14 Thaco Research, Ltd. Methods for the quantitative analysis of organic compounds
SE520392C2 (sv) * 1996-09-27 2003-07-01 Creative Peptides Sweden Ab C Specifika peptider för behandling av diabetes mellitus
US6197340B1 (en) * 1998-05-28 2001-03-06 Medical Research Institute Controlled release lipoic acid
PT1299348E (pt) 2000-06-29 2008-05-12 Emisphere Tech Inc Compostos e composições para administração de agentes activos
ES2321693T3 (es) * 2000-09-06 2009-06-10 Emisphere Technologies, Inc. Compuestos de acido cianofenoxi carboxilico y composiciones para la administracion de agentes activos.
US20020147135A1 (en) * 2000-12-21 2002-10-10 Oliver Schnell Method and device for producing an adapted travel treatment plan for administering a medicine in the event of a long-haul journey
US7060675B2 (en) * 2001-02-15 2006-06-13 Nobex Corporation Methods of treating diabetes mellitus
US6828297B2 (en) * 2001-06-04 2004-12-07 Nobex Corporation Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US20030198666A1 (en) * 2002-01-07 2003-10-23 Richat Abbas Oral insulin therapy
CA2471144C (en) 2002-01-09 2011-06-07 Emisphere Technologies, Inc. Polymorphs of sodium 4-[(4-chloro-2-hydroxybenzoyl)amino]butanoate
US7137951B2 (en) * 2002-10-23 2006-11-21 Joseph Pilarski Method of food and insulin dose management for a diabetic subject
US8273794B2 (en) 2004-05-14 2012-09-25 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents

Also Published As

Publication number Publication date
AU2004204727A1 (en) 2004-07-29
CA2511530A1 (en) 2004-07-29
HK1085133A1 (en) 2006-08-18
US7384914B2 (en) 2008-06-10
WO2004062587A3 (en) 2005-04-28
AU2004204727B2 (en) 2006-10-19
US20060178296A1 (en) 2006-08-10
JP2006515620A (ja) 2006-06-01
EP1592438A2 (en) 2005-11-09
NZ541058A (en) 2008-06-30
EP1592438B1 (en) 2014-02-26
ES2465496T3 (es) 2014-06-05
CA2511530C (en) 2013-07-09
EP1592438A4 (en) 2009-07-08
AU2004204727B8 (en) 2006-11-09
WO2004062587A2 (en) 2004-07-29

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