JP5438886B2 - ＩｇＡ１沈着症の治療 - Google Patents
ＩｇＡ１沈着症の治療 Download PDFInfo
- Publication number
- JP5438886B2 JP5438886B2 JP2006509132A JP2006509132A JP5438886B2 JP 5438886 B2 JP5438886 B2 JP 5438886B2 JP 2006509132 A JP2006509132 A JP 2006509132A JP 2006509132 A JP2006509132 A JP 2006509132A JP 5438886 B2 JP5438886 B2 JP 5438886B2
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- Prior art keywords
- iga1
- protease
- tag
- molecule
- iga1 protease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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| US8440191B2 (en) | 2005-11-18 | 2013-05-14 | Tufts Medical Center | Clearance of abnormal IGA1 in IGA1 deposition diseases |
| US20080027554A1 (en) * | 2006-07-31 | 2008-01-31 | Talmadge Karen D | Kit and methods of treatment of an intervertebral disc |
| WO2010118337A2 (en) * | 2009-04-10 | 2010-10-14 | Biomarin Pharmaceutical Inc. | Methods of enhancing yield of active iga protease |
| US8841109B2 (en) | 2009-04-20 | 2014-09-23 | The University Of Kansas | IGA1 protease polypeptide agents and uses thereof |
| CN104073474A (zh) * | 2014-06-27 | 2014-10-01 | 樊均明 | 一种IgA1酶及其制备方法和应用 |
| WO2017223534A2 (en) * | 2016-06-24 | 2017-12-28 | Anthera Pharmaceuticals, Inc. | Methods of treating iga nephropathy and henoch-schönlein purpura nephritis using a b-cell activating factor (baff) inhibitor |
| CN115197328B (zh) * | 2021-04-09 | 2025-05-16 | 北京大学第一医院 | 一种可清除体内免疫球蛋白A的重组融合蛋白酶及其制备方法和在治疗IgA肾病中的应用 |
| MX2024009171A (es) * | 2022-01-29 | 2024-08-09 | Univ Peking First Hospital | Formas truncadas de la iga proteasa, proteinas de fusion que comprenden una forma truncada de la iga proteasa y usos de estas. |
| KR20250114034A (ko) | 2022-11-11 | 2025-07-28 | 아이간 바이오사이언스 | Iga 프로테아제 폴리펩타이드 제제 |
| WO2025183146A1 (ja) * | 2024-02-29 | 2025-09-04 | 積水メディカル株式会社 | 免疫学的測定方法、免疫学的測定用試薬、免疫学的測定用検体前処理液、免疫学的測定用試薬キット、及び非特異反応抑制剤 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| DK130889A (da) * | 1989-03-17 | 1990-09-18 | Mogens Kilian | Immunoglobulin a1-proteaser (iga1-proteaser), fremgangsmaade til genteknologisk fremstilling af saadanne enzymer samt vaccine indeholdende enzymerne og fragmenter deraf til immunisering mod bakteriel meningitis og andre sygdomme fremkaldt af iga1-protease-producerende bakterier |
| ATE396399T1 (de) * | 1998-03-31 | 2008-06-15 | Asahi Kasei Pharma Corp | Verfahren zur untersuchung der iga-nephropathie |
| ATE421976T1 (de) | 1999-05-18 | 2009-02-15 | Dyax Corp | Fab fragmentbibliotheken und verfahren für deren verwendung |
| WO2004096157A2 (en) | 2003-03-07 | 2004-11-11 | New England Medical Center Hospitals, Inc. | Treatment of igai deposition diseases |
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- 2004-03-05 JP JP2006509132A patent/JP5438886B2/ja not_active Expired - Lifetime
- 2004-03-05 KR KR1020057016464A patent/KR20060015468A/ko not_active Ceased
- 2004-03-05 DE DE602004031199T patent/DE602004031199D1/de not_active Expired - Lifetime
- 2004-03-05 CN CN2004800062159A patent/CN1777673B/zh not_active Expired - Lifetime
- 2004-03-05 KR KR1020137005608A patent/KR20130026513A/ko not_active Ceased
- 2004-03-05 AT AT04749338T patent/ATE496992T1/de not_active IP Right Cessation
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2015096079A (ja) | 2015-05-21 |
| EP1603511A2 (en) | 2005-12-14 |
| ATE496992T1 (de) | 2011-02-15 |
| US20090041746A1 (en) | 2009-02-12 |
| EP1603511B1 (en) | 2011-01-26 |
| CN1777673A (zh) | 2006-05-24 |
| US7407653B2 (en) | 2008-08-05 |
| US8216568B2 (en) | 2012-07-10 |
| CA2558873C (en) | 2015-10-20 |
| JP2011101645A (ja) | 2011-05-26 |
| JP2013230157A (ja) | 2013-11-14 |
| CA2558873A1 (en) | 2004-11-11 |
| WO2004096157A3 (en) | 2005-10-20 |
| WO2004096157A2 (en) | 2004-11-11 |
| ES2360291T3 (es) | 2011-06-02 |
| US20090130084A1 (en) | 2009-05-21 |
| JP2006519619A (ja) | 2006-08-31 |
| CN1777673B (zh) | 2010-04-28 |
| DE602004031199D1 (de) | 2011-03-10 |
| EP1603511A4 (en) | 2007-06-06 |
| KR20130026513A (ko) | 2013-03-13 |
| US20050136062A1 (en) | 2005-06-23 |
| HK1090950A1 (zh) | 2007-01-05 |
| KR20060015468A (ko) | 2006-02-17 |
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