JP5431323B2 - 炎症および免疫関連用途のためのピリジン化合物 - Google Patents

炎症および免疫関連用途のためのピリジン化合物 Download PDF

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JP5431323B2
JP5431323B2 JP2010519940A JP2010519940A JP5431323B2 JP 5431323 B2 JP5431323 B2 JP 5431323B2 JP 2010519940 A JP2010519940 A JP 2010519940A JP 2010519940 A JP2010519940 A JP 2010519940A JP 5431323 B2 JP5431323 B2 JP 5431323B2
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pyridin
phenyl
chloro
thiazol
disease
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JP2010535215A (ja
JP2010535215A5 (OSRAM
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チェン，ショウジュン
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シンタ ファーマシューティカルズ コーポレーション
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    • C07—ORGANIC CHEMISTRY
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
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  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
JP2010519940A 2007-08-01 2008-07-31 炎症および免疫関連用途のためのピリジン化合物 Expired - Fee Related JP5431323B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96278907P 2007-08-01 2007-08-01
US60/962,789 2007-08-01
PCT/US2008/009306 WO2009017819A1 (en) 2007-08-01 2008-07-31 Pyridine compounds for inflammation and immune-related uses

Publications (3)

Publication Number Publication Date
JP2010535215A JP2010535215A (ja) 2010-11-18
JP2010535215A5 JP2010535215A5 (OSRAM) 2011-09-15
JP5431323B2 true JP5431323B2 (ja) 2014-03-05

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JP2010519940A Expired - Fee Related JP5431323B2 (ja) 2007-08-01 2008-07-31 炎症および免疫関連用途のためのピリジン化合物

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Country Link
US (1) US20120064121A1 (OSRAM)
EP (1) EP2182808A4 (OSRAM)
JP (1) JP5431323B2 (OSRAM)
CA (1) CA2695148A1 (OSRAM)
TW (1) TW200911800A (OSRAM)
WO (1) WO2009017819A1 (OSRAM)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI444187B (zh) 2005-01-25 2014-07-11 Synta Pharmaceuticals Corp 用於炎症及免疫相關用途之噻吩化合物
JP5430943B2 (ja) 2006-01-25 2014-03-05 シンタ ファーマシューティカルズ コーポレーション 炎症及び免疫関連用途のための置換芳香族化合物
EP1984337B1 (en) 2006-01-25 2014-04-30 Synta Pharmaceuticals Corp. Vinyl-phenyl derivatives for inflammation and immune-related uses
US8623871B2 (en) 2006-01-25 2014-01-07 Synta Pharmaceuticals Corp. Substituted biaryl compounds for inflammation and immune-related uses
WO2007109362A2 (en) 2006-03-20 2007-09-27 Synta Pharmaceuticals Corp. Benzoimidazolyl-parazine compounds for inflammation and immune-related uses
US8779154B2 (en) 2006-09-26 2014-07-15 Qinglin Che Fused ring compounds for inflammation and immune-related uses
WO2010039237A1 (en) * 2008-10-01 2010-04-08 Synta Pharmaceuticals Corp. Compounds for inflammation and immune-related uses
US8993612B2 (en) 2009-10-08 2015-03-31 Rhizen Pharmaceuticals Sa Modulators of calcium release-activated calcium channel and methods for treatment of non-small cell lung cancer
US8377970B2 (en) 2009-10-08 2013-02-19 Rhizen Pharmaceuticals Sa Modulators of calcium release-activated calcium channel
US20120231006A1 (en) 2009-11-20 2012-09-13 Amgen Inc. Anti-orai1 antigen binding proteins and uses thereof
EP2632906B1 (en) * 2010-10-30 2016-04-06 Lupin Limited Oxazoline and isoxazoline derivatives as crac modulators
CA2871270A1 (en) 2012-05-02 2013-11-07 Lupin Limited Substituted pyridine compounds as crac modulators
IN2014MN02127A (OSRAM) 2012-05-02 2015-09-11 Lupin Ltd
WO2014203217A1 (en) 2013-06-21 2014-12-24 Lupin Limited Substituted heterocyclic compounds as crac modulators
EP3013810A1 (en) 2013-06-24 2016-05-04 Lupin Limited Chromane and chromene derivatives and their use as crac modulators
CN107847548B (zh) 2015-05-18 2022-06-14 贝思以色列女会吏医学中心公司 P物质、肥大细胞脱颗粒抑制剂和周围神经病
KR20210062023A (ko) 2018-09-14 2021-05-28 리젠 파마슈티컬스 아게 Crac 억제제 및 코르티코스테로이드를 포함하는 조성물 및 그의 사용 방법
CN115209952B (zh) 2020-01-13 2025-05-30 维基分析有限公司 经取代的吡唑并嘧啶及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1651232E (pt) * 2003-07-23 2011-02-16 Synta Pharmaceuticals Corp Compostos para inflamação e utilizações imunorelacionadas
TWI441819B (zh) * 2005-01-07 2014-06-21 Synta Pharmaceuticals Corp 用於炎症及免疫相關用途之化合物
US20070254926A1 (en) * 2006-01-31 2007-11-01 Jun Jiang Pyridylphenyl compounds for inflammation and immune-related uses

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Publication number Publication date
WO2009017819A1 (en) 2009-02-05
JP2010535215A (ja) 2010-11-18
EP2182808A1 (en) 2010-05-12
US20120064121A1 (en) 2012-03-15
CA2695148A1 (en) 2009-02-05
TW200911800A (en) 2009-03-16
EP2182808A4 (en) 2011-09-21

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