JP5417667B2 - 抗原ペプチドおよび化学療法薬を用いる膵癌のための併用療法 - Google Patents

抗原ペプチドおよび化学療法薬を用いる膵癌のための併用療法 Download PDF

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JP5417667B2
JP5417667B2 JP2010506728A JP2010506728A JP5417667B2 JP 5417667 B2 JP5417667 B2 JP 5417667B2 JP 2010506728 A JP2010506728 A JP 2010506728A JP 2010506728 A JP2010506728 A JP 2010506728A JP 5417667 B2 JP5417667 B2 JP 5417667B2
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seq
peptide
amino acid
cancer
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JP2010536714A5 (cg-RX-API-DMAC7.html
JP2010536714A (ja
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裕機 山上
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Oncotherapy Science Inc
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Oncotherapy Science Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/80Vaccine for a specifically defined cancer
    • A61K2039/852Pancreas

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
JP2010506728A 2007-08-24 2008-08-19 抗原ペプチドおよび化学療法薬を用いる膵癌のための併用療法 Expired - Fee Related JP5417667B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US95792307P 2007-08-24 2007-08-24
US60/957,923 2007-08-24
PCT/JP2008/002232 WO2009028150A1 (en) 2007-08-24 2008-08-19 Combination therapy for pancreatic cancer using an antigenic peptide and chemotherapeutic agent

Publications (3)

Publication Number Publication Date
JP2010536714A JP2010536714A (ja) 2010-12-02
JP2010536714A5 JP2010536714A5 (cg-RX-API-DMAC7.html) 2011-09-29
JP5417667B2 true JP5417667B2 (ja) 2014-02-19

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Family Applications (1)

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JP2010506728A Expired - Fee Related JP5417667B2 (ja) 2007-08-24 2008-08-19 抗原ペプチドおよび化学療法薬を用いる膵癌のための併用療法

Country Status (19)

Country Link
US (1) US8703713B2 (cg-RX-API-DMAC7.html)
EP (1) EP2195003A4 (cg-RX-API-DMAC7.html)
JP (1) JP5417667B2 (cg-RX-API-DMAC7.html)
KR (1) KR20100047899A (cg-RX-API-DMAC7.html)
CN (1) CN101883577A (cg-RX-API-DMAC7.html)
AR (1) AR068020A1 (cg-RX-API-DMAC7.html)
AU (1) AU2008292966C1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0815726A2 (cg-RX-API-DMAC7.html)
CA (1) CA2697501A1 (cg-RX-API-DMAC7.html)
IL (1) IL204143A (cg-RX-API-DMAC7.html)
MX (1) MX2010002178A (cg-RX-API-DMAC7.html)
MY (1) MY160406A (cg-RX-API-DMAC7.html)
NZ (1) NZ583578A (cg-RX-API-DMAC7.html)
RU (1) RU2472522C2 (cg-RX-API-DMAC7.html)
SG (1) SG183770A1 (cg-RX-API-DMAC7.html)
TW (1) TWI436775B (cg-RX-API-DMAC7.html)
UA (1) UA100702C2 (cg-RX-API-DMAC7.html)
WO (1) WO2009028150A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201001580B (cg-RX-API-DMAC7.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103073620B (zh) 2002-09-12 2014-12-10 肿瘤疗法科学股份有限公司 Kdr肽和包括该肽的疫苗
US20080034017A1 (en) * 2006-08-04 2008-02-07 Dominic Giampaolo Links to a common item in a data structure
TW201109029A (en) 2009-06-11 2011-03-16 Oncotherapy Science Inc Vaccine therapy for choroidal neovascularization
US20130149302A1 (en) * 2010-05-28 2013-06-13 Chugai Seiyaku Kabushiki Kaisha Therapeutic agents for pancreatic cancer
DE102013214023B4 (de) * 2013-07-17 2015-02-12 Siemens Aktiengesellschaft Verfahren zu einem Auswerten und Vergleichen von zeitlich aufeinander folgenden kombinierten medizinischen Bildgebungsuntersuchungen sowie ein medizinisches Bildgebungssystem, das zu einem Ausführen des erfindungsgemäßen Verfahrens ausgelegt ist
DK3597742T3 (da) * 2014-10-09 2022-10-03 Univ Yamaguchi Car-udtrykkende vektor og car-udtrykkende t-celler
AU2015333728B2 (en) * 2014-10-14 2020-07-30 Riptide Bioscience, Inc. Peptide-based methods for treating pancreatic cancer
EP3626260A4 (en) * 2017-05-19 2021-05-19 Keio University PEPTIDE VACCINE AND PEPTIDE VACCINE COMPOSITION FOR CRANIAL NERVOUS DISEASE
US10413584B1 (en) 2018-08-29 2019-09-17 Riptide Bioscience, Inc. Peptides having immunomodulatory properties
US10548944B1 (en) 2018-10-19 2020-02-04 Riptide Bioscience, Inc. Antimicrobial peptides and methods of using the same
CN114959031A (zh) * 2022-05-20 2022-08-30 上海交通大学医学院附属瑞金医院 胰腺腺癌预后评估的标志物组合及其应用

Family Cites Families (20)

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Publication number Priority date Publication date Assignee Title
GB213645A (en) 1922-12-22 1924-03-24 Frank Lincoln Morse Improvements in and relating to chain and sprocket wheel gearing
US3265572A (en) * 1961-09-20 1966-08-09 S B Penick And Company Process for preparing tyrociding and product produced thereby
US4526988A (en) * 1983-03-10 1985-07-02 Eli Lilly And Company Difluoro antivirals and intermediate therefor
JP3734262B2 (ja) 1993-03-25 2006-01-11 メルク エンド カンパニー インコーポレーテッド 血管内皮細胞増殖因子阻害剤
US6080728A (en) 1996-07-16 2000-06-27 Mixson; A. James Carrier: DNA complexes containing DNA encoding anti-angiogenic peptides and their use in gene therapy
DE19638745C2 (de) 1996-09-11 2001-05-10 Schering Ag Monoklonale Antikörper gegen die extrazelluläre Domäne des menschlichen VEGF - Rezeptorproteins (KDR)
WO1998031794A1 (fr) 1997-01-17 1998-07-23 Toa Gosei Co., Ltd. Polypeptide liant le facteur vegf
WO1999040118A1 (en) 1998-02-04 1999-08-12 Kyowa Hakko Kogyo Co., Ltd. Antibodies against human vegf receptor kdr
GB9804121D0 (en) 1998-02-26 1998-04-22 Cancer Res Campaign Tech Anti-angiogenic vaccines: materials and methods relating thereto
AU3850299A (en) 1998-05-20 1999-12-06 Kyowa Hakko Kogyo Co. Ltd. Vegf activity inhibitors
US7087411B2 (en) 1999-06-08 2006-08-08 Regeneron Pharmaceuticals, Inc. Fusion protein capable of binding VEGF
US7320793B2 (en) 2001-01-19 2008-01-22 Cytos Biotechnology Ag Molecular antigen array
CU23178A1 (es) * 2002-04-15 2006-09-22 Ct Ingenieria Genetica Biotech INMUNOTERAPIA ACTIVA ANTIANGIOGéNICA
CN103073620B (zh) * 2002-09-12 2014-12-10 肿瘤疗法科学股份有限公司 Kdr肽和包括该肽的疫苗
EP1567169A4 (en) 2002-11-04 2009-10-21 Xenoport Inc GEMCITABINE PROMOTERS, THEIR PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
DE602005027673D1 (de) * 2004-03-05 2011-06-09 Vegenics Pty Ltd Materialien und verfahren für wachstumsfaktorbindende konstrukte
CN1960732A (zh) * 2004-06-03 2007-05-09 霍夫曼-拉罗奇有限公司 用吉西他滨和egfr-抑制剂治疗
JP5022911B2 (ja) 2004-12-17 2012-09-12 イーライ リリー アンド カンパニー ゲムシタビンのアミドプロドラック、組成物、及びそれらの使用
US20060216288A1 (en) * 2005-03-22 2006-09-28 Amgen Inc Combinations for the treatment of cancer
WO2008099908A1 (ja) 2007-02-16 2008-08-21 Oncotherapy Science, Inc. 脈絡膜新生血管のワクチン療法

Also Published As

Publication number Publication date
MX2010002178A (es) 2010-03-18
CN101883577A (zh) 2010-11-10
US8703713B2 (en) 2014-04-22
ZA201001580B (en) 2011-02-23
UA100702C2 (ru) 2013-01-25
TWI436775B (zh) 2014-05-11
KR20100047899A (ko) 2010-05-10
NZ583578A (en) 2012-07-27
AU2008292966A1 (en) 2009-03-05
TW200914037A (en) 2009-04-01
JP2010536714A (ja) 2010-12-02
EP2195003A4 (en) 2011-07-06
WO2009028150A1 (en) 2009-03-05
IL204143A (en) 2013-04-30
EP2195003A1 (en) 2010-06-16
MY160406A (en) 2017-03-15
BRPI0815726A2 (pt) 2016-01-05
AU2008292966C1 (en) 2013-03-14
CA2697501A1 (en) 2009-03-05
US20110082088A1 (en) 2011-04-07
RU2010111139A (ru) 2011-09-27
AR068020A1 (es) 2009-10-28
AU2008292966B2 (en) 2012-07-19
SG183770A1 (en) 2012-09-27
RU2472522C2 (ru) 2013-01-20

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