JP5405307B2 - 改善された性質を有する再構成サーファクタント - Google Patents

改善された性質を有する再構成サーファクタント Download PDF

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Publication number
JP5405307B2
JP5405307B2 JP2009531932A JP2009531932A JP5405307B2 JP 5405307 B2 JP5405307 B2 JP 5405307B2 JP 2009531932 A JP2009531932 A JP 2009531932A JP 2009531932 A JP2009531932 A JP 2009531932A JP 5405307 B2 JP5405307 B2 JP 5405307B2
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surfactant
polypeptide
native
reconstituted
protein
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English (en)
Japanese (ja)
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JP2010505937A5 (enExample
JP2010505937A (ja
Inventor
ヨハンソン，ヤン
カーステッド，トーレ
ロバートソン，ベングト
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キエージ・フアルマチエウテイチ・エツセ・ピ・ア
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/395—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Fire-Extinguishing Compositions (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
JP2009531932A 2006-10-13 2007-09-28 改善された性質を有する再構成サーファクタント Active JP5405307B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06021521 2006-10-13
EP06021521.7 2006-10-13
PCT/IB2007/002841 WO2008044109A1 (en) 2006-10-13 2007-09-28 Reconstituted surfactants having improved properties

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013161238A Division JP2013241449A (ja) 2006-10-13 2013-08-02 改善された性質を有する再構成サーファクタント

Publications (3)

Publication Number Publication Date
JP2010505937A JP2010505937A (ja) 2010-02-25
JP2010505937A5 JP2010505937A5 (enExample) 2010-09-24
JP5405307B2 true JP5405307B2 (ja) 2014-02-05

Family

ID=39079026

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009531932A Active JP5405307B2 (ja) 2006-10-13 2007-09-28 改善された性質を有する再構成サーファクタント
JP2013161238A Pending JP2013241449A (ja) 2006-10-13 2013-08-02 改善された性質を有する再構成サーファクタント

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013161238A Pending JP2013241449A (ja) 2006-10-13 2013-08-02 改善された性質を有する再構成サーファクタント

Country Status (35)

Country Link
US (2) US8183210B2 (enExample)
EP (1) EP2078038B1 (enExample)
JP (2) JP5405307B2 (enExample)
KR (1) KR101328851B1 (enExample)
CN (2) CN103169947B (enExample)
AR (2) AR063263A1 (enExample)
AU (1) AU2007306075B2 (enExample)
BR (1) BRPI0715317B1 (enExample)
CA (1) CA2666344C (enExample)
CL (1) CL2007002931A1 (enExample)
CO (1) CO6400235A2 (enExample)
CY (1) CY1114716T1 (enExample)
DK (1) DK2078038T3 (enExample)
EA (1) EA015802B1 (enExample)
ES (1) ES2438727T3 (enExample)
GE (1) GEP20125531B (enExample)
HR (1) HRP20140052T1 (enExample)
IL (1) IL198075A (enExample)
JO (1) JO2963B1 (enExample)
MA (1) MA31062B1 (enExample)
ME (2) ME02326B (enExample)
MX (1) MX343064B (enExample)
MY (1) MY148127A (enExample)
NO (1) NO342038B1 (enExample)
NZ (1) NZ576189A (enExample)
PE (1) PE20081184A1 (enExample)
PL (1) PL2078038T3 (enExample)
PT (1) PT2078038E (enExample)
RS (1) RS53172B (enExample)
SI (1) SI2078038T1 (enExample)
TN (1) TN2009000099A1 (enExample)
TW (1) TWI388333B (enExample)
UA (1) UA94477C2 (enExample)
WO (1) WO2008044109A1 (enExample)
ZA (1) ZA200902481B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008011559A2 (en) 2006-07-20 2008-01-24 University Of Rochester Synthetic lung surfactant and use thereof
EP1997502A1 (en) * 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties
US8399406B2 (en) * 2009-06-05 2013-03-19 Chiesi Farmaceutici S.P.A. Reconstituted surfactant composition containing analogs of surfactant protein B (SP-B) and surfactant protein C (SP-C)
CN101948526B (zh) * 2010-09-02 2012-12-05 华东理工大学 一种肺泡表面活性蛋白质(sp-b和sp-c)的分离纯化方法
US9815869B2 (en) 2012-02-09 2017-11-14 University Of Rochester SP-B and SP-C peptides, synthetic lung surfactants, and use thereof
US20130303726A1 (en) * 2012-04-17 2013-11-14 Chiesi Farmaceutici S.P.A. Method for the preparation of surfactant peptides
BR112015009486B1 (pt) 2012-11-21 2022-06-14 Chiesi Farmaceutici S.P.A Surfactante reconstituído, formulação farmacêutica, kit e uso de surfactante reconstituído
EP3393489B1 (en) * 2015-12-17 2021-09-01 Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center Synthetic lung surfactant with enhanced stability and effectiveness
CA3016810C (en) 2016-03-07 2024-04-02 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Compositions and methods for administering ppar.gamma. agonists, surfactant peptides and phospholipids
CN109562139A (zh) 2016-08-24 2019-04-02 奇斯药制品公司 包含重构肺表面活性物质组合物的稳定药物制剂
US20230257446A1 (en) 2020-01-28 2023-08-17 Chiesi Farmaceutici S.P.A. Polypeptides having improved properties
EP4228691A4 (en) * 2020-10-16 2025-01-01 Biosuperior Technology, Inc. PULMONARY TREATMENT COMPOSITIONS
WO2025024609A1 (en) * 2023-07-25 2025-01-30 Biosuperior Technology, Inc. Polypeptides for lung surfactant compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0706374B1 (en) * 1993-06-30 1997-12-10 Genentech, Inc. Method for preparing liposomes
IT1308180B1 (it) * 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
US7065342B1 (en) * 1999-11-23 2006-06-20 Gofigure, L.L.C. System and mobile cellular telephone device for playing recorded music
ITMI20021058A1 (it) 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
EP1481665A1 (en) * 2003-05-30 2004-12-01 CHIESI FARMACEUTICI S.p.A. Novel lipid mixtures for synthetic surfactants
WO2008011559A2 (en) * 2006-07-20 2008-01-24 University Of Rochester Synthetic lung surfactant and use thereof
EP1997502A1 (en) 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties
EP2022798A1 (en) 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetic pulmonary surfactant peptides

Also Published As

Publication number Publication date
WO2008044109A1 (en) 2008-04-17
HK1134497A1 (en) 2010-04-30
PT2078038E (pt) 2013-12-12
JO2963B1 (en) 2016-03-15
EA200900373A1 (ru) 2009-10-30
US20130079275A1 (en) 2013-03-28
MA31062B1 (fr) 2010-01-04
ES2438727T3 (es) 2014-01-20
TW200824705A (en) 2008-06-16
ME02326B (me) 2016-06-20
US8183210B2 (en) 2012-05-22
CN103169947B (zh) 2014-10-29
CO6400235A2 (es) 2012-03-15
CY1114716T1 (el) 2016-10-05
CA2666344A1 (en) 2008-04-17
IL198075A0 (en) 2011-08-01
CN103169947A (zh) 2013-06-26
TN2009000099A1 (en) 2010-08-19
NZ576189A (en) 2011-09-30
CN101522711A (zh) 2009-09-02
AU2007306075A1 (en) 2008-04-17
AR063263A1 (es) 2009-01-14
PL2078038T3 (pl) 2014-05-30
KR20090083892A (ko) 2009-08-04
HRP20140052T1 (hr) 2014-02-28
MEP12109A (en) 2011-12-20
US9238058B2 (en) 2016-01-19
JP2013241449A (ja) 2013-12-05
AR113422A2 (es) 2020-04-29
EP2078038A1 (en) 2009-07-15
BRPI0715317A2 (pt) 2013-07-09
ZA200902481B (en) 2010-07-28
CA2666344C (en) 2017-04-18
CN101522711B (zh) 2013-11-13
EA015802B1 (ru) 2011-12-30
MY148127A (en) 2013-02-28
EP2078038B1 (en) 2013-11-20
JP2010505937A (ja) 2010-02-25
AU2007306075B2 (en) 2012-08-09
GEP20125531B (en) 2012-05-25
HK1185274A1 (en) 2014-02-14
TWI388333B (zh) 2013-03-11
SI2078038T1 (sl) 2014-02-28
RS53172B (sr) 2014-06-30
BRPI0715317B1 (pt) 2021-10-05
MX2009003638A (es) 2009-04-22
CL2007002931A1 (es) 2008-03-24
MX343064B (es) 2016-10-24
KR101328851B1 (ko) 2013-11-14
PE20081184A1 (es) 2008-09-26
NO20091441L (no) 2009-06-23
UA94477C2 (ru) 2011-05-10
US20100004173A1 (en) 2010-01-07
DK2078038T3 (da) 2013-12-02
IL198075A (en) 2016-04-21
NO342038B1 (no) 2018-03-19

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