JP5395669B2 - 血液試料中の第ｘａ因子インヒビターの電気化学測定のための方法および装置 - Google Patents

血液試料中の第ｘａ因子インヒビターの電気化学測定のための方法および装置 Download PDF

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JP5395669B2
JP5395669B2 JP2009533745A JP2009533745A JP5395669B2 JP 5395669 B2 JP5395669 B2 JP 5395669B2 JP 2009533745 A JP2009533745 A JP 2009533745A JP 2009533745 A JP2009533745 A JP 2009533745A JP 5395669 B2 JP5395669 B2 JP 5395669B2
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factor
reagent
activator
test element
sample
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JP2010508499A (ja
JP2010508499A5 (enExample
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ホルン，カリーナ
デルゲ，リーゼル
クルツィジウク，マルガレーテ
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F Hoffmann La Roche AG
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2009533745A 2006-10-31 2007-10-27 血液試料中の第ｘａ因子インヒビターの電気化学測定のための方法および装置 Active JP5395669B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06123234A EP1918718A1 (de) 2006-10-31 2006-10-31 Verfahren und Vorrichtungen zur elektrochemischen Bestimmung von Faktor Xa-Inhibitoren in Blutproben
EP06123234.4 2006-10-31
PCT/EP2007/009347 WO2008052718A1 (de) 2006-10-31 2007-10-27 Verfahren und vorrichtungen zur elektrochemischen bestimmung von faktor xa-inhibitoren in blutproben

Publications (3)

Publication Number Publication Date
JP2010508499A JP2010508499A (ja) 2010-03-18
JP2010508499A5 JP2010508499A5 (enExample) 2010-08-05
JP5395669B2 true JP5395669B2 (ja) 2014-01-22

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JP2009533745A Active JP5395669B2 (ja) 2006-10-31 2007-10-27 血液試料中の第ｘａ因子インヒビターの電気化学測定のための方法および装置

Country Status (7)

Country Link
US (2) US8636894B2 (enExample)
EP (2) EP1918718A1 (enExample)
JP (1) JP5395669B2 (enExample)
CN (1) CN101535498B (enExample)
CA (1) CA2667957C (enExample)
ES (1) ES2444011T3 (enExample)
WO (1) WO2008052718A1 (enExample)

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EP2471945A1 (de) * 2010-12-30 2012-07-04 Siemens Healthcare Diagnostics Products GmbH Verfahren zur Bestimmung von Inhibitoren der Gerinnung
WO2012124800A1 (ja) * 2011-03-16 2012-09-20 学校法人 芝浦工業大学 抗凝固薬測定用センサ
EP2818871A1 (en) * 2013-06-28 2014-12-31 Roche Diagniostics GmbH Means and methods for universal calibration of anti-Factor Xa tests
EP3198272B1 (en) 2014-09-26 2022-04-06 Abbott Point Of Care, Inc. Cartridge device identification for coagulation assays in fluid samples
EP3954457A3 (en) 2014-09-26 2022-05-18 Abbott Point Of Care Inc Microfabricated device with micro-environment sensors for assaying coagulation in fluid samples
WO2016049557A1 (en) 2014-09-26 2016-03-31 Abbott Point Of Care Inc. Ellagic acid formulations for use in coagulation assays
CN106999930B (zh) 2014-09-26 2020-09-08 雅培医护站股份有限公司 用于测定流体样本中的凝结的具有分段射流的盒设备
US10114031B2 (en) 2014-09-26 2018-10-30 Abbott Point Of Care Inc. Single channel cartridge device for coagulation assays in fluid samples
US10048282B2 (en) 2014-09-26 2018-08-14 Abbott Point Of Care Inc. Cartridge device with fluidic junctions for coagulation assays in fluid samples
CN107110874B (zh) 2014-09-26 2019-06-04 雅培医护站股份有限公司 用于测定流体样品中的凝固的传感器
CN104714036B (zh) * 2015-04-01 2016-06-01 成都协和生物技术有限责任公司 抗凝血酶iii活性测定试剂盒的制备方法
CN105203479A (zh) * 2015-09-21 2015-12-30 山东万邦赛诺康生化制药股份有限公司 用血凝仪测定肝素或低分子量肝素效价的方法
US10794896B2 (en) * 2016-01-29 2020-10-06 Sony Corporation Blood coagulation system examination module, blood coagulation system examination system, blood coagulation system examination method, and determination method of parameter for blood coagulation system examination module
US20190265185A1 (en) * 2016-10-20 2019-08-29 Universal Biosensors Pty Ltd Non-biohazardous solutions and methods for testing analysers
US12073926B2 (en) 2020-09-21 2024-08-27 Instrumentation Laboratory Company Detecting and monitoring oral anticoagulants or intravenous direct thrombin inhibitors in a blood sample
CN117309966A (zh) * 2022-06-22 2023-12-29 广州好芝生物科技有限公司 血液样本中Xa因子抑制剂的检测方法及装置
CN115032164B (zh) * 2022-08-10 2022-12-06 山东省食品药品检验研究院 一种肝素钠中是否含有凝血因子Xa直接抑制剂的检测方法
CN117191724A (zh) * 2023-08-25 2023-12-08 江苏瑞庆诊断技术有限公司 一种抗Xa测定试剂盒（发色底物法）LMWH和UFH2合1校准曲线的研制方法

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EP0360871B2 (en) 1988-03-03 1999-06-30 Nippon Shoji Kabushiki Kaisha Method for measuring biological activity of antithrombin iii and reagent kit for the measurement
JP3094165B2 (ja) * 1990-11-05 2000-10-03 バクスター、ダイアグノスチックス、インコーポレイテッド 抗凝固剤濃度測定方法
US5308756A (en) * 1991-11-20 1994-05-03 Baxter Diagnostics Inc. Protein S chromogenic assay
EP0738389A1 (en) * 1992-09-04 1996-10-23 Gradipore Limited Apparatus and method for detecting coagulation/lysis of liquids
JPH08507148A (ja) * 1993-02-17 1996-07-30 カーディオヴァスキュラー ダイアグノスティクス，インク． 固相化学カスケードイムノアッセイおよびアフィニティアッセイ
US5762770A (en) 1994-02-21 1998-06-09 Boehringer Mannheim Corporation Electrochemical biosensor test strip
ZA953361B (en) * 1994-04-26 1996-01-12 Selectide Corp Factor Xa inhibitors
NL1006429C2 (nl) * 1997-06-27 1998-12-29 Univ Maastricht Werkwijze voor het bepalen van het heparinegehalte.
US5997817A (en) 1997-12-05 1999-12-07 Roche Diagnostics Corporation Electrochemical biosensor test strip
AU5062100A (en) * 1999-06-14 2001-01-02 Novo Nordisk A/S Fviia/tf activity inhibiting compounds
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EP1261861B1 (de) * 2000-02-21 2004-09-29 Roche Diagnostics GmbH Elektrochemischer sensor zur bestimmung der blutgerinnung, ein entsprechendes blutgerinnungsmesssystem sowie ein verfahren zur bestimmung der blutgerinnung
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EP1682863B1 (en) * 2003-09-22 2012-07-04 University Of North Carolina At Chapel Hill Soluble phospholipids for use in clotting factor assays

Also Published As

Publication number Publication date
EP2079849B1 (de) 2013-11-20
ES2444011T3 (es) 2014-02-21
HK1137783A1 (en) 2010-08-06
CN101535498B (zh) 2012-11-14
WO2008052718A1 (de) 2008-05-08
EP2079849A1 (de) 2009-07-22
JP2010508499A (ja) 2010-03-18
US9594042B2 (en) 2017-03-14
US20090236238A1 (en) 2009-09-24
EP1918718A1 (de) 2008-05-07
CA2667957A1 (en) 2008-05-08
US20140106383A1 (en) 2014-04-17
CN101535498A (zh) 2009-09-16
US8636894B2 (en) 2014-01-28
CA2667957C (en) 2013-03-05

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