JP5394249B2 - Ｉａｐ阻害剤とｆｌｔ３阻害剤の組合せ剤 - Google Patents
Ｉａｐ阻害剤とｆｌｔ３阻害剤の組合せ剤 Download PDFInfo
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- JP5394249B2 JP5394249B2 JP2009539434A JP2009539434A JP5394249B2 JP 5394249 B2 JP5394249 B2 JP 5394249B2 JP 2009539434 A JP2009539434 A JP 2009539434A JP 2009539434 A JP2009539434 A JP 2009539434A JP 5394249 B2 JP5394249 B2 JP 5394249B2
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- methylamino
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| CA2607940C (en) | 2005-05-18 | 2009-12-15 | Aegera Therapeutics Inc. | Bir domain binding compounds |
| WO2007048224A1 (en) | 2005-10-25 | 2007-05-03 | Aegera Therapeutics Inc. | Iap bir domain binding compounds |
| TWI543988B (zh) | 2006-03-16 | 2016-08-01 | 科學製藥股份有限公司 | 結合於細胞凋亡抑制蛋白（ｉａｐ）之桿狀病毒ｉａｐ重複序列（ｂｉｒ）區域之化合物 |
| MY159563A (en) | 2006-05-16 | 2017-01-13 | Pharmascience Inc | Iap bir domain binding compounds |
| US20100056495A1 (en) * | 2006-07-24 | 2010-03-04 | Tetralogic Pharmaceuticals Corporation | Dimeric iap inhibitors |
| ES2882855T3 (es) * | 2008-05-16 | 2021-12-02 | Dana Farber Cancer Inst Inc | Inmunomodulación por inhibidores de IAP |
| US20100317593A1 (en) * | 2009-06-12 | 2010-12-16 | Astrazeneca Ab | 2,3-dihydro-1h-indene compounds |
| NZ602368A (en) | 2010-02-12 | 2014-10-31 | Pharmascience Inc | Iap bir domain binding compounds |
| US20140243276A1 (en) | 2011-09-30 | 2014-08-28 | Tetralogic Pharmaceuticals Corporation | Smac mimetic (birinapant) for use in the treatment of proliferative diseases (cancer) |
| ES2982449T3 (es) | 2013-06-25 | 2024-10-16 | Walter & Eliza Hall Inst Medical Res | Miméticos Smac para su uso en el tratamiento de una infección persistente por VIH |
| CA2974651A1 (en) | 2014-01-24 | 2015-07-30 | Children's Hospital Of Eastern Ontario Research Institute Inc. | Smc combination therapy for the treatment of cancer |
| KR101954370B1 (ko) | 2018-07-25 | 2019-03-05 | 한미약품 주식회사 | 피리미딘 화합물 및 이를 포함하는 암의 예방 또는 치료용 약학 조성물 |
| PE20212153A1 (es) | 2019-02-22 | 2021-11-09 | Hanmi Pharm Ind Co Ltd | Composicion farmaceutica que comprende un inhibidor de flt3 y un agente hipometilante para tratar la leucemia mieloide aguda |
| CA3130244A1 (en) | 2019-02-22 | 2020-08-27 | Hanmi Pharm. Co., Ltd. | Pharmaceutical composition comprising flt3 inhibitor and hypomethylating agent for treating acute myeloid leukemia |
| KR20200102948A (ko) | 2019-02-22 | 2020-09-01 | 한미약품 주식회사 | Flt3 저해제 및 iap 길항제를 포함하는 급성 골수성 백혈병의 치료를 위한 약학적 조합물 |
| SG11202110742TA (en) | 2019-04-02 | 2021-10-28 | Aligos Therapeutics Inc | Compounds targeting prmt5 |
| KR20210002015A (ko) | 2019-06-27 | 2021-01-06 | 한미약품 주식회사 | Flt3 저해제 및 화학치료제를 포함하는 급성 골수성 백혈병 치료용 약학적 조성물 |
| HUP2200468A1 (hu) | 2020-04-29 | 2023-03-28 | X Chem Zrt | IAP antagonisták és gyógyászati alkalmazásuk |
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| US20060128632A1 (en) | 2002-07-02 | 2006-06-15 | Sharma Sushil K | Peptide inhibitors of smac protein binding to inhibitor of apoptosis proteins (iap) |
| WO2005097791A1 (en) | 2004-04-07 | 2005-10-20 | Novartis Ag | Inhibitors of iap |
| CN101340947B (zh) | 2005-12-20 | 2012-09-05 | 诺瓦提斯公司 | Iap-抑制剂和紫杉烷7的组合 |
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- 2007-11-27 KR KR1020097013350A patent/KR20090087094A/ko not_active Abandoned
- 2007-11-27 JP JP2009539434A patent/JP5394249B2/ja not_active Expired - Fee Related
- 2007-11-27 EP EP07868853A patent/EP2089024B1/en active Active
- 2007-11-27 WO PCT/US2007/085579 patent/WO2008067280A2/en not_active Ceased
- 2007-11-27 AT AT07868853T patent/ATE509629T1/de active
- 2007-11-27 AU AU2007325280A patent/AU2007325280B2/en not_active Ceased
- 2007-11-27 MX MX2009005621A patent/MX2009005621A/es active IP Right Grant
- 2007-11-27 RU RU2009124590/15A patent/RU2456983C2/ru not_active IP Right Cessation
- 2007-11-27 PT PT07868853T patent/PT2089024E/pt unknown
- 2007-11-27 PL PL07868853T patent/PL2089024T3/pl unknown
- 2007-11-27 US US12/516,062 patent/US8492429B2/en not_active Expired - Fee Related
- 2007-11-27 CA CA002670498A patent/CA2670498A1/en not_active Abandoned
- 2007-11-27 BR BRPI0719543-5A patent/BRPI0719543A2/pt not_active IP Right Cessation
-
2009
- 2009-05-04 IL IL198551A patent/IL198551A0/en unknown
- 2009-05-22 TN TNP2009000206A patent/TN2009000206A1/fr unknown
- 2009-05-27 GT GT200900142A patent/GT200900142A/es unknown
- 2009-06-03 MA MA31946A patent/MA30966B1/fr unknown
- 2009-06-24 NO NO20092417A patent/NO20092417L/no not_active Application Discontinuation
- 2009-06-25 CO CO09066298A patent/CO6210722A2/es not_active Application Discontinuation
- 2009-06-26 EC EC2009009472A patent/ECSP099472A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2009005621A (es) | 2009-06-12 |
| AU2007325280A1 (en) | 2008-06-05 |
| EP2089024B1 (en) | 2011-05-18 |
| EP2089024A2 (en) | 2009-08-19 |
| MA30966B1 (fr) | 2009-12-01 |
| BRPI0719543A2 (pt) | 2014-02-25 |
| AU2007325280B2 (en) | 2011-03-10 |
| NO20092417L (no) | 2009-08-25 |
| WO2008067280A3 (en) | 2008-08-07 |
| ATE509629T1 (de) | 2011-06-15 |
| RU2009124590A (ru) | 2011-01-10 |
| IL198551A0 (en) | 2010-02-17 |
| ECSP099472A (es) | 2009-10-30 |
| US8492429B2 (en) | 2013-07-23 |
| CO6210722A2 (es) | 2010-10-20 |
| PL2089024T3 (pl) | 2011-10-31 |
| US20100056467A1 (en) | 2010-03-04 |
| TN2009000206A1 (en) | 2010-10-18 |
| KR20090087094A (ko) | 2009-08-14 |
| WO2008067280A2 (en) | 2008-06-05 |
| PT2089024E (pt) | 2011-08-31 |
| CA2670498A1 (en) | 2008-06-05 |
| RU2456983C2 (ru) | 2012-07-27 |
| JP2010511059A (ja) | 2010-04-08 |
| GT200900142A (es) | 2010-06-24 |
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