JP5385274B2 - ホスファプラチン、ならびにシスプラチンおよびカルボプラチンに対し耐性を有する癌の治療におけるその使用 - Google Patents

ホスファプラチン、ならびにシスプラチンおよびカルボプラチンに対し耐性を有する癌の治療におけるその使用 Download PDF

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JP5385274B2
JP5385274B2 JP2010520294A JP2010520294A JP5385274B2 JP 5385274 B2 JP5385274 B2 JP 5385274B2 JP 2010520294 A JP2010520294 A JP 2010520294A JP 2010520294 A JP2010520294 A JP 2010520294A JP 5385274 B2 JP5385274 B2 JP 5385274B2
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platinum
isolated
cancer
composition
substituted
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JP2010535803A (ja
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ボース，ラシンドラ，エヌ．
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オハイオ ユニバーシティー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2010520294A 2007-08-06 2008-08-06 ホスファプラチン、ならびにシスプラチンおよびカルボプラチンに対し耐性を有する癌の治療におけるその使用 Active JP5385274B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US95412607P 2007-08-06 2007-08-06
US60/954,126 2007-08-06
US97392607P 2007-09-20 2007-09-20
US60/973,926 2007-09-20
PCT/US2008/072398 WO2009021082A2 (fr) 2007-08-06 2008-08-06 Phosphoplatines et leur utilisation dans le traitement de cancers résistant au cisplatine et carboplatine

Related Child Applications (1)

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JP2013120309A Division JP5647300B2 (ja) 2007-08-06 2013-06-07 ホスファプラチン、ならびにシスプラチンおよびカルボプラチンに対し耐性を有する癌の治療におけるその使用

Publications (2)

Publication Number Publication Date
JP2010535803A JP2010535803A (ja) 2010-11-25
JP5385274B2 true JP5385274B2 (ja) 2014-01-08

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JP2010520294A Active JP5385274B2 (ja) 2007-08-06 2008-08-06 ホスファプラチン、ならびにシスプラチンおよびカルボプラチンに対し耐性を有する癌の治療におけるその使用
JP2013120309A Active JP5647300B2 (ja) 2007-08-06 2013-06-07 ホスファプラチン、ならびにシスプラチンおよびカルボプラチンに対し耐性を有する癌の治療におけるその使用

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JP2013120309A Active JP5647300B2 (ja) 2007-08-06 2013-06-07 ホスファプラチン、ならびにシスプラチンおよびカルボプラチンに対し耐性を有する癌の治療におけるその使用

Country Status (13)

Country Link
US (4) US7700649B2 (fr)
EP (2) EP2668949A1 (fr)
JP (2) JP5385274B2 (fr)
CN (1) CN101801369B (fr)
CY (1) CY1115504T1 (fr)
DK (1) DK2173337T3 (fr)
ES (1) ES2495743T3 (fr)
HK (1) HK1143551A1 (fr)
HR (1) HRP20140808T1 (fr)
PL (1) PL2173337T3 (fr)
PT (1) PT2173337E (fr)
SI (1) SI2173337T1 (fr)
WO (2) WO2009021082A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2668949A1 (fr) 2007-08-06 2013-12-04 Ohio University Phosphoplatines et leur utilisation dans le traitement de cancers résistant au cisplatine et carboplatine
CN103037859A (zh) * 2010-06-04 2013-04-10 俄亥俄大学 磷铂及其在治疗癌症中的用途
EP2663301A1 (fr) * 2011-01-12 2013-11-20 Ohio University Phosphaplatines ayant des propriétés anti-angiogéniques, anti-métastatiques et pro-apoptotiques, et leurs utilisations
KR101901477B1 (ko) 2011-07-08 2018-09-21 다우 글로벌 테크놀로지스 엘엘씨 블로운 필름에 적합한 폴리에틸렌 배합 조성물, 그 제조 방법, 및 그로부터 제조된 필름
MX357865B (es) 2011-10-05 2018-07-25 N Bose Rathindra Procedimientos eficientes para preparación a gran escala de agentes antitumorales de fosfaplatinos.
CN104010508B (zh) * 2011-10-05 2017-03-15 理辛德拉·N·博斯 用于大规模制备磷铂类抗肿瘤剂的高效方法
CN110269940A (zh) 2011-10-20 2019-09-24 奈瑞姆生物技术公司 用于治疗癌症的治疗组合
HUE046327T2 (hu) * 2012-05-24 2020-03-30 Phosplatin Therapeutics Llc Tisztítási eljárás foszfaplatin vegyületekhez
JP6382231B2 (ja) * 2013-02-22 2018-08-29 ユニバーシティ オブ ヒューストンＵｎｉｖｅｒｓｉｔｙ Ｏｆ Ｈｏｕｓｔｏｎ 神経保護剤としてのホスファプラチン
EP3107534A4 (fr) * 2014-02-19 2017-09-06 The University Of Houston System Compositions et procédés pour le traitement de maladies neurodégénératives
JP7304128B2 (ja) 2014-06-11 2023-07-06 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム 白金耐性の克服における使用のためのテキサフィリン－白金（ｉｖ）コンジュゲート及び組成物
EP3397642A1 (fr) 2015-12-30 2018-11-07 Atilim Universitesi Complexes mononucléaires et hétérodinucléaires ciblés sur l'adn
CN110381952B (zh) * 2017-01-06 2023-10-20 弗斯普拉廷治疗有限公司 作为治疗剂用于治疗骨癌或血癌的磷铂化合物
CA3074020A1 (fr) * 2017-09-08 2019-03-14 Phosplatin Therapeutics Llc Composes de phosphaplatine utilises en tant qu'agents immunomodulateurs et leurs utilisations therapeutiques

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234500A (en) 1979-03-07 1980-11-18 Engelhard Minerals & Chemicals Corporation Ethylenediamine platinum(II) and 1,2-diamino-cyclohexane platinum(II) pyrophosphate complexes
US4291027A (en) 1979-03-07 1981-09-22 Engelhard Minerals & Chemicals Corp. Method for treating tumors with ethylenediamine platinum (II) and 1,2-diaminocyclohexane-platinum (II) pyrophosphate complexes
CA2017739A1 (fr) * 1989-07-18 1991-01-18 Leslie S. Hollis Complexes cis-diamineplatine avec ligands de methanediphosphonate et de methanediphosphonate substitue comme agents antitumoraux
JP4463274B2 (ja) * 2003-06-27 2010-05-19 明 小谷 ビスホスホネート錯体
EP2177525A1 (fr) * 2007-07-06 2010-04-21 TMRC Co., Ltd. Composé complexe métallique, composition thérapeutique contre le cancer comprenant le composé complexe métallique comme principe actif et intermédiaire pour la production du composé complexe métallique
EP2668949A1 (fr) 2007-08-06 2013-12-04 Ohio University Phosphoplatines et leur utilisation dans le traitement de cancers résistant au cisplatine et carboplatine

Also Published As

Publication number Publication date
HRP20140808T1 (hr) 2014-10-24
EP2668949A1 (fr) 2013-12-04
JP5647300B2 (ja) 2014-12-24
US8034964B2 (en) 2011-10-11
US8445710B2 (en) 2013-05-21
SI2173337T1 (sl) 2014-10-30
PL2173337T3 (pl) 2014-11-28
DK2173337T3 (da) 2014-09-15
EP2173337A4 (fr) 2010-10-27
HK1143551A1 (en) 2011-01-07
US20100233293A1 (en) 2010-09-16
CN101801369A (zh) 2010-08-11
WO2009021081A3 (fr) 2009-05-07
EP2173337B1 (fr) 2014-07-30
CN101801369B (zh) 2012-09-19
WO2009021082A2 (fr) 2009-02-12
US8653132B2 (en) 2014-02-18
US20090042838A1 (en) 2009-02-12
ES2495743T3 (es) 2014-09-17
WO2009021082A3 (fr) 2009-04-23
EP2173337A2 (fr) 2010-04-14
US20130237503A1 (en) 2013-09-12
US20110313182A1 (en) 2011-12-22
PT2173337E (pt) 2014-09-03
JP2010535803A (ja) 2010-11-25
JP2013227218A (ja) 2013-11-07
US7700649B2 (en) 2010-04-20
CY1115504T1 (el) 2017-01-04
WO2009021081A2 (fr) 2009-02-12

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