JP5349966B2 - 新規アクチビン受容体およびその使用 - Google Patents
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- JP5349966B2 JP5349966B2 JP2008539077A JP2008539077A JP5349966B2 JP 5349966 B2 JP5349966 B2 JP 5349966B2 JP 2008539077 A JP2008539077 A JP 2008539077A JP 2008539077 A JP2008539077 A JP 2008539077A JP 5349966 B2 JP5349966 B2 JP 5349966B2
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013027391A (ja) * | 2005-11-01 | 2013-02-07 | Amgen Inc | 新規アクチビン受容体およびその使用 |
| US9610327B2 (en) | 2007-03-06 | 2017-04-04 | Amgen Inc. | Variant activin receptor polypeptides, alone or in combination with chemotherapy, and uses thereof |
| US9809638B2 (en) | 2007-03-06 | 2017-11-07 | Amgen Inc. | Variant activin receptor |
| US10308704B2 (en) | 2008-11-26 | 2019-06-04 | Amgen Inc. | Isolated nucleic acid molecules encoding stabilized receptor polypeptides and uses thereof |
| US11541070B2 (en) | 2013-02-01 | 2023-01-03 | Atara Biotherapeutics, Inc. | Administration of an anti-activin-A compound to a subject |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2272864A3 (en) | 2002-12-20 | 2011-02-16 | Amgen Inc. | Binding agents which inhibit myostatin |
| ES2551852T3 (es) | 2004-07-23 | 2015-11-24 | Acceleron Pharma Inc. | Polipéptidos del receptor ActRII |
| EA201692543A1 (ru) | 2005-11-23 | 2017-08-31 | Акселерон Фарма Инк. | Антагонисты активина-actriia и их применение для стимулирования роста кости |
| US8128933B2 (en) | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
| ES2569365T3 (es) * | 2006-11-29 | 2016-05-10 | Nationwide Children's Hospital | Inhibición de miostatina para la potenciación de músculo y/o la mejora de la función muscular |
| EP2468291B1 (en) | 2006-12-18 | 2017-11-22 | Acceleron Pharma, Inc. | Activin-actrii antagonists and uses for increasing red blood cell levels |
| US8895016B2 (en) | 2006-12-18 | 2014-11-25 | Acceleron Pharma, Inc. | Antagonists of activin-actriia and uses for increasing red blood cell levels |
| CA2677007A1 (en) | 2007-02-01 | 2008-08-07 | Acceleron Pharma Inc. | Activin-actriia antagonists and uses for treating or preventing breast cancer |
| TWI782836B (zh) | 2007-02-02 | 2022-11-01 | 美商艾瑟勒朗法瑪公司 | 衍生自ActRIIB的變體與其用途 |
| CA3039330C (en) | 2007-02-09 | 2021-11-09 | Acceleron Pharma Inc. | Activin-actriia antagonists and uses for promoting bone growth in cancer patients |
| US8501678B2 (en) | 2007-03-06 | 2013-08-06 | Atara Biotherapeutics, Inc. | Variant activin receptor polypeptides and uses thereof |
| CN103877564A (zh) | 2007-09-18 | 2014-06-25 | 阿塞勒隆制药公司 | 活化素-actriia拮抗剂和减少或抑制fsh分泌的用途 |
| JP5922928B2 (ja) | 2008-08-14 | 2016-05-24 | アクセルロン ファーマ， インコーポレイテッド | 赤血球レベルを高めるためのｇｄｆトラップの使用 |
| US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
| AU2013216639B2 (en) * | 2008-11-26 | 2016-05-05 | Amgen Inc. | Variants of activin IIB receptor polypeptides and uses thereof |
| EP2387412A4 (en) | 2009-01-13 | 2013-04-03 | Acceleron Pharma Inc | PROCESS FOR INCREASING THE ADIPONECTIN MIRROR |
| NO2424895T3 (enExample) * | 2009-04-27 | 2018-02-03 | ||
| CN102482339B (zh) | 2009-06-08 | 2015-06-17 | 阿塞勒隆制药公司 | 用于增加产热脂肪细胞的方法 |
| EP2440577A4 (en) | 2009-06-12 | 2013-01-23 | Acceleron Pharma Inc | SHORTEN ACTRIIB FC FUSION PROTEINS |
| ES2796121T3 (es) * | 2009-08-13 | 2020-11-25 | Acceleron Pharma Inc | Uso combinado de trampas de GDF y activadores del receptor de la eritropoyetina para aumentar los niveles de glóbulos rojos |
| CA2779472C (en) * | 2009-11-03 | 2021-03-16 | Acceleron Pharma Inc. | The use of a composition comprising an activin type iib receptor polypeptide in the treatment of fatty liver disease |
| ES2658292T3 (es) | 2009-11-17 | 2018-03-09 | Acceleron Pharma, Inc. | Proteínas ActRIIB y variantes y usos de las mismas con respecto a la inducción de la utrofina para el tratamiento de la distrofia muscular |
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| CN103298832A (zh) | 2010-11-08 | 2013-09-11 | 阿塞勒隆制药公司 | Actriia结合剂及其用途 |
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| JP2013027391A (ja) * | 2005-11-01 | 2013-02-07 | Amgen Inc | 新規アクチビン受容体およびその使用 |
| JP2014195469A (ja) * | 2005-11-01 | 2014-10-16 | アムジェン インコーポレイテッド | 新規アクチビン受容体およびその使用 |
| JP2016187361A (ja) * | 2005-11-01 | 2016-11-04 | アムジェン インコーポレイテッド | 新規アクチビン受容体およびその使用 |
| US9610327B2 (en) | 2007-03-06 | 2017-04-04 | Amgen Inc. | Variant activin receptor polypeptides, alone or in combination with chemotherapy, and uses thereof |
| US9809638B2 (en) | 2007-03-06 | 2017-11-07 | Amgen Inc. | Variant activin receptor |
| US10407487B2 (en) | 2007-03-06 | 2019-09-10 | Amgen Inc. | Variant activin receptor |
| US10308704B2 (en) | 2008-11-26 | 2019-06-04 | Amgen Inc. | Isolated nucleic acid molecules encoding stabilized receptor polypeptides and uses thereof |
| US11685770B2 (en) | 2008-11-26 | 2023-06-27 | Amgen Inc. | Stabilized receptor polypeptides and uses thereof |
| US11541070B2 (en) | 2013-02-01 | 2023-01-03 | Atara Biotherapeutics, Inc. | Administration of an anti-activin-A compound to a subject |
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| US8614292B2 (en) | 2013-12-24 |
| CA2627200A1 (en) | 2007-05-10 |
| JP2013027391A (ja) | 2013-02-07 |
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| EP1943273B1 (en) | 2012-04-18 |
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| CA2627200C (en) | 2013-09-10 |
| JP2016187361A (ja) | 2016-11-04 |
| US20110281796A1 (en) | 2011-11-17 |
| US20070117130A1 (en) | 2007-05-24 |
| JP2009513162A (ja) | 2009-04-02 |
| JP6072731B2 (ja) | 2017-02-01 |
| ES2385581T3 (es) | 2012-07-26 |
| AU2006308614B2 (en) | 2011-11-17 |
| ATE554101T1 (de) | 2012-05-15 |
| JP2014195469A (ja) | 2014-10-16 |
| US20160152683A1 (en) | 2016-06-02 |
| WO2007053775A1 (en) | 2007-05-10 |
| EP1943273A1 (en) | 2008-07-16 |
| US20140088008A1 (en) | 2014-03-27 |
| AU2006308614A1 (en) | 2007-05-10 |
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