JP5349966B2 - 新規アクチビン受容体およびその使用 - Google Patents
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- JP5349966B2 JP5349966B2 JP2008539077A JP2008539077A JP5349966B2 JP 5349966 B2 JP5349966 B2 JP 5349966B2 JP 2008539077 A JP2008539077 A JP 2008539077A JP 2008539077 A JP2008539077 A JP 2008539077A JP 5349966 B2 JP5349966 B2 JP 5349966B2
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013027391A (ja) * | 2005-11-01 | 2013-02-07 | Amgen Inc | 新規アクチビン受容体およびその使用 |
| US9610327B2 (en) | 2007-03-06 | 2017-04-04 | Amgen Inc. | Variant activin receptor polypeptides, alone or in combination with chemotherapy, and uses thereof |
| US9809638B2 (en) | 2007-03-06 | 2017-11-07 | Amgen Inc. | Variant activin receptor |
| US10308704B2 (en) | 2008-11-26 | 2019-06-04 | Amgen Inc. | Isolated nucleic acid molecules encoding stabilized receptor polypeptides and uses thereof |
| US11541070B2 (en) | 2013-02-01 | 2023-01-03 | Atara Biotherapeutics, Inc. | Administration of an anti-activin-A compound to a subject |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| AU2003301195B2 (en) | 2002-12-20 | 2010-01-07 | Amgen Inc. | Binding agents which inhibit myostatin |
| JP2008507288A (ja) | 2004-07-23 | 2008-03-13 | アクセルロン ファーマ インコーポレーテッド | ＡｃｔＲＩＩ受容体ポリペプチド、方法、および組成物 |
| BRPI0618947B1 (pt) | 2005-11-23 | 2022-07-19 | Acceleron Pharma Inc | Polipeptídeo actriia que se liga à ativina, polinucleotídeo isolado, polinucleotídeo recombinante, métodopara preparar um polipeptídeo actriia que se liga à ativina, preparação farmacêutica e uso de uma proteína de fusão actriia-fc para promover o crescimento ósseo e inibir a ressorção óssea |
| US8128933B2 (en) | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
| WO2008067480A2 (en) * | 2006-11-29 | 2008-06-05 | Nationwide Children's Hospital | Myostatin inhibition for enhancing muscle and/or improving muscle function |
| CA2672758C (en) | 2006-12-18 | 2019-07-30 | Acceleron Pharma Inc. | Activin-actrii antagonists and uses for increasing red blood cell levels |
| US8895016B2 (en) | 2006-12-18 | 2014-11-25 | Acceleron Pharma, Inc. | Antagonists of activin-actriia and uses for increasing red blood cell levels |
| TWI584815B (zh) | 2007-02-01 | 2017-06-01 | 艾瑟勒朗法瑪公司 | 活化素-ＡｃｔＲＩＩａ拮抗劑及其治療或預防乳癌之用途 |
| TW201627320A (zh) | 2007-02-02 | 2016-08-01 | 艾瑟勒朗法瑪公司 | 衍生自ＡｃｔＲＩＩＢ的變體與其用途 |
| MX2009008510A (es) | 2007-02-09 | 2010-01-15 | Acceleron Pharma Inc | Antagonistas de activina-actriia y usos para promover el crecimiento de huesos en pacientes con cancer. |
| US8501678B2 (en) | 2007-03-06 | 2013-08-06 | Atara Biotherapeutics, Inc. | Variant activin receptor polypeptides and uses thereof |
| CA2699936A1 (en) | 2007-09-18 | 2009-03-26 | Acceleron Pharma Inc. | Activin-actriia antagonists and uses for decreasing or inhibiting fsh secretion |
| DK3750552T5 (da) | 2008-08-14 | 2024-08-26 | Acceleron Pharma Inc | Gdf-fælder |
| US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
| AU2013216639B2 (en) * | 2008-11-26 | 2016-05-05 | Amgen Inc. | Variants of activin IIB receptor polypeptides and uses thereof |
| AU2010204985A1 (en) | 2009-01-13 | 2011-08-04 | Acceleron Pharma Inc. | Methods for increasing adiponectin |
| ES2655877T3 (es) * | 2009-04-27 | 2018-02-22 | Novartis Ag | Composiciones y métodos para aumentar el crecimiento muscular |
| MX355042B (es) | 2009-06-08 | 2018-04-02 | Acceleon Pharma Inc | Metodos para aumentar adipositos termogenicos. |
| CN107267520A (zh) | 2009-06-12 | 2017-10-20 | 阿塞勒隆制药公司 | 截短的actriib‑fc融合蛋白 |
| KR102170682B1 (ko) | 2009-08-13 | 2020-10-28 | 악셀레론 파마 인코포레이티드 | 적혈구 수준을 증가시키기 위한 ｇｄｆ 트랩과 에리트로포이에틴 수용체 활성인자의 병용 |
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| JP2013027391A (ja) * | 2005-11-01 | 2013-02-07 | Amgen Inc | 新規アクチビン受容体およびその使用 |
| JP2014195469A (ja) * | 2005-11-01 | 2014-10-16 | アムジェン インコーポレイテッド | 新規アクチビン受容体およびその使用 |
| JP2016187361A (ja) * | 2005-11-01 | 2016-11-04 | アムジェン インコーポレイテッド | 新規アクチビン受容体およびその使用 |
| US9610327B2 (en) | 2007-03-06 | 2017-04-04 | Amgen Inc. | Variant activin receptor polypeptides, alone or in combination with chemotherapy, and uses thereof |
| US9809638B2 (en) | 2007-03-06 | 2017-11-07 | Amgen Inc. | Variant activin receptor |
| US10407487B2 (en) | 2007-03-06 | 2019-09-10 | Amgen Inc. | Variant activin receptor |
| US10308704B2 (en) | 2008-11-26 | 2019-06-04 | Amgen Inc. | Isolated nucleic acid molecules encoding stabilized receptor polypeptides and uses thereof |
| US11685770B2 (en) | 2008-11-26 | 2023-06-27 | Amgen Inc. | Stabilized receptor polypeptides and uses thereof |
| US12630608B2 (en) | 2008-11-26 | 2026-05-19 | Amgen Inc. | Stabilized receptor polypeptides and uses thereof |
| US11541070B2 (en) | 2013-02-01 | 2023-01-03 | Atara Biotherapeutics, Inc. | Administration of an anti-activin-A compound to a subject |
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| US8067562B2 (en) | 2011-11-29 |
| EP1943273B1 (en) | 2012-04-18 |
| US20070117130A1 (en) | 2007-05-24 |
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| US20110281796A1 (en) | 2011-11-17 |
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| US9284364B2 (en) | 2016-03-15 |
| ATE554101T1 (de) | 2012-05-15 |
| US8614292B2 (en) | 2013-12-24 |
| JP2014195469A (ja) | 2014-10-16 |
| EP1943273A1 (en) | 2008-07-16 |
| JP2013027391A (ja) | 2013-02-07 |
| CA2627200C (en) | 2013-09-10 |
| CA2627200A1 (en) | 2007-05-10 |
| JP2016187361A (ja) | 2016-11-04 |
| JP2009513162A (ja) | 2009-04-02 |
| AU2006308614B2 (en) | 2011-11-17 |
| ES2385581T3 (es) | 2012-07-26 |
| US20160152683A1 (en) | 2016-06-02 |
| AU2006308614A1 (en) | 2007-05-10 |
| US20140088008A1 (en) | 2014-03-27 |
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