JP5349966B2 - 新規アクチビン受容体およびその使用 - Google Patents
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- JP5349966B2 JP5349966B2 JP2008539077A JP2008539077A JP5349966B2 JP 5349966 B2 JP5349966 B2 JP 5349966B2 JP 2008539077 A JP2008539077 A JP 2008539077A JP 2008539077 A JP2008539077 A JP 2008539077A JP 5349966 B2 JP5349966 B2 JP 5349966B2
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013027391A (ja) * | 2005-11-01 | 2013-02-07 | Amgen Inc | 新規アクチビン受容体およびその使用 |
| US9610327B2 (en) | 2007-03-06 | 2017-04-04 | Amgen Inc. | Variant activin receptor polypeptides, alone or in combination with chemotherapy, and uses thereof |
| US9809638B2 (en) | 2007-03-06 | 2017-11-07 | Amgen Inc. | Variant activin receptor |
| US10308704B2 (en) | 2008-11-26 | 2019-06-04 | Amgen Inc. | Isolated nucleic acid molecules encoding stabilized receptor polypeptides and uses thereof |
| US11541070B2 (en) | 2013-02-01 | 2023-01-03 | Atara Biotherapeutics, Inc. | Administration of an anti-activin-A compound to a subject |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS52815B (sr) | 2002-12-20 | 2013-10-31 | Amgen Inc. | Vezivna sredstva koja inhibiraju miostatin |
| EP1771470B1 (en) | 2004-07-23 | 2013-06-26 | Acceleron Pharma Inc. | Actrii receptor polypeptides, methods and compositions |
| RS58231B1 (sr) | 2005-11-23 | 2019-03-29 | Acceleron Pharma Inc | Antagonisti aktivin-actriia i primene za stimulaciju rasta kostiju |
| US8128933B2 (en) | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
| CA2693178C (en) * | 2006-11-29 | 2018-12-04 | Nationwide Children's Hospital, Inc. | Myostatin inhibition for enhancing muscle and/or improving muscle function |
| MX2009006651A (es) | 2006-12-18 | 2009-08-26 | Acceleron Pharma Inc | Antagonistas de activina-actrii y usos para incrementar los niveles de globulos rojo. |
| US8895016B2 (en) | 2006-12-18 | 2014-11-25 | Acceleron Pharma, Inc. | Antagonists of activin-actriia and uses for increasing red blood cell levels |
| KR101526613B1 (ko) | 2007-02-01 | 2015-06-26 | 악셀레론 파마 인코포레이티드 | 액티빈-ａｃｔｒⅱａ 길항제 및 유방암을 치료 또는 예방하기 위한 이들의 용도 |
| TW201940502A (zh) | 2007-02-02 | 2019-10-16 | 美商艾瑟勒朗法瑪公司 | 衍生自ＡｃｔＲＩＩＢ的變體與其用途 |
| TW201808334A (zh) | 2007-02-09 | 2018-03-16 | 艾瑟勒朗法瑪公司 | 包含ＡｃｔＲＩＩａ-Ｆｃ融合蛋白的醫藥組合物；ＡｃｔＲＩＩａ-Ｆｃ融合蛋白於治療或預防與癌症相關的骨質流失之用途；ＡｃｔＲＩＩａ-Ｆｃ融合蛋白於治療或預防多發性骨髓瘤之用途 |
| US8501678B2 (en) | 2007-03-06 | 2013-08-06 | Atara Biotherapeutics, Inc. | Variant activin receptor polypeptides and uses thereof |
| EP2207562B1 (en) | 2007-09-18 | 2017-05-31 | Acceleron Pharma, Inc. | Activin-actriia antagonists and uses for decreasing or inhibiting fsh secretion |
| US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
| HUE063136T2 (hu) | 2008-08-14 | 2023-12-28 | Acceleron Pharma Inc | GDF-Csapdák |
| AU2013216639B2 (en) * | 2008-11-26 | 2016-05-05 | Amgen Inc. | Variants of activin IIB receptor polypeptides and uses thereof |
| CA2749544A1 (en) | 2009-01-13 | 2010-07-22 | Acceleron Pharma Inc. | Methods for increasing adiponectin |
| EA027071B1 (ru) * | 2009-04-27 | 2017-06-30 | Новартис Аг | АНТИТЕЛО К ActRIIB И СОДЕРЖАЩАЯ ЕГО КОМПОЗИЦИЯ |
| KR20120049214A (ko) | 2009-06-08 | 2012-05-16 | 악셀레론 파마 인코포레이티드 | 발열성 지방세포를 증가시키는 방법 |
| US8293881B2 (en) | 2009-06-12 | 2012-10-23 | Acceleron Pharma Inc. | Isolated nucleic acid encoding a truncated ActRIIB fusion protein |
| KR102170682B1 (ko) | 2009-08-13 | 2020-10-28 | 악셀레론 파마 인코포레이티드 | 적혈구 수준을 증가시키기 위한 ｇｄｆ 트랩과 에리트로포이에틴 수용체 활성인자의 병용 |
| EP2496247B1 (en) | 2009-11-03 | 2017-08-23 | Acceleron Pharma, Inc. | Methods for treating fatty liver disease |
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| JP2013027391A (ja) * | 2005-11-01 | 2013-02-07 | Amgen Inc | 新規アクチビン受容体およびその使用 |
| JP2014195469A (ja) * | 2005-11-01 | 2014-10-16 | アムジェン インコーポレイテッド | 新規アクチビン受容体およびその使用 |
| JP2016187361A (ja) * | 2005-11-01 | 2016-11-04 | アムジェン インコーポレイテッド | 新規アクチビン受容体およびその使用 |
| US9610327B2 (en) | 2007-03-06 | 2017-04-04 | Amgen Inc. | Variant activin receptor polypeptides, alone or in combination with chemotherapy, and uses thereof |
| US9809638B2 (en) | 2007-03-06 | 2017-11-07 | Amgen Inc. | Variant activin receptor |
| US10407487B2 (en) | 2007-03-06 | 2019-09-10 | Amgen Inc. | Variant activin receptor |
| US10308704B2 (en) | 2008-11-26 | 2019-06-04 | Amgen Inc. | Isolated nucleic acid molecules encoding stabilized receptor polypeptides and uses thereof |
| US11685770B2 (en) | 2008-11-26 | 2023-06-27 | Amgen Inc. | Stabilized receptor polypeptides and uses thereof |
| US11541070B2 (en) | 2013-02-01 | 2023-01-03 | Atara Biotherapeutics, Inc. | Administration of an anti-activin-A compound to a subject |
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| US20070117130A1 (en) | 2007-05-24 |
| ES2385581T3 (es) | 2012-07-26 |
| ATE554101T1 (de) | 2012-05-15 |
| JP2014195469A (ja) | 2014-10-16 |
| CA2627200C (en) | 2013-09-10 |
| US8067562B2 (en) | 2011-11-29 |
| US9284364B2 (en) | 2016-03-15 |
| JP6072731B2 (ja) | 2017-02-01 |
| EP1943273A1 (en) | 2008-07-16 |
| US20110281796A1 (en) | 2011-11-17 |
| US8614292B2 (en) | 2013-12-24 |
| JP2016187361A (ja) | 2016-11-04 |
| CA2627200A1 (en) | 2007-05-10 |
| US20140088008A1 (en) | 2014-03-27 |
| JP2009513162A (ja) | 2009-04-02 |
| AU2006308614A1 (en) | 2007-05-10 |
| WO2007053775A1 (en) | 2007-05-10 |
| EP1943273B1 (en) | 2012-04-18 |
| JP2013027391A (ja) | 2013-02-07 |
| AU2006308614B2 (en) | 2011-11-17 |
| US20160152683A1 (en) | 2016-06-02 |
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