JP5336888B2 - Method and apparatus for dissolving powder for dialysis - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a method and device of dissolving a powdered medicine for dialysis, capable of feeding the powdered medicine in a short period, easily adaptable to a large central dialysis system by reducing the dissolving time, capable of simplifying the whole device without requiring a high accuracy of a powder feeding mechanism, and capable of easily preventing adhesion and scattering, etc. of powder. <P>SOLUTION: In preparing a stock solution for dialysis of a prescribed concentration by mixing and dissolving the powdered medicine for dialysis and dilution water at a prescribe mixing ratio in a dissolution tub, the powdered medicine for dialysis is fed into the dissolution tub first, and the fed powdered medicine is measured for each dissolution tub. Next, in feeding the dilution water, the quantity of fed dilution water is controlled by measuring the quantity for each dissolution tub so that the dissolution water is mixed with the powdered medicine for dialysis at a prescribed mixing ratio to the measured quantity of fed powdered medicine for dialysis. The method and device of dissolving the powdered medicine for dialysis are characterized by the above control. <P>COPYRIGHT: (C)2010,JPO&amp;INPIT

Description

  The present invention relates to a dialysis powder solution dissolving method and apparatus for preparing a dialysate used for hemodialysis, particularly a dialysis stock solution having a predetermined concentration.

  In particular, in a so-called central dialysis system that allows centralized management of hemodialysis for a large number of people, the dialysate used for individual hemodialysis, in particular the dialysis stock solution of a predetermined concentration, is diluted with the dialysis powder. It is often prepared in a large amount by mixing water with a predetermined mixing ratio and dissolving the dialysis powder with diluted water. This stock solution for dialysis having a predetermined concentration is usually prepared in a batch system. For example, by having a hopper for storing a dialysis powder and a supply means capable of controlling the supply of a predetermined amount of dialysis powder from the hopper, mixing the supplied dialysis powder and dilution water 2. Description of the Related Art There is known a dialysis powder solution dissolving apparatus capable of preparing a dialysis stock solution having a predetermined concentration.

  In such a conventional dialysis powder solution dissolving apparatus, basically, dilution water is supplied to the dissolution tank, and the supply amount of the dialysis powder to be mixed is adjusted with respect to the dilution water amount, and fine powder injection of the powder is performed. The concentration of the dialysis stock solution to be prepared is finally adjusted.

  However, such conventional methods and apparatuses are used to adjust the final concentration in the dissolution tank by adding small amounts of powder to the end, and a lot of time is required for dissolving the dialysis stock solution and adjusting the concentration (especially the concentration). The feedback method requires a lot of time), and recovery when a failure occurs is extremely difficult. Moreover, high precision is required for the powder supply means for fine powder injection, and the mechanism becomes complicated. Further, the small-scale powder pouring causes the powder to remain halfway at the tip of the powder supply means at the final stage, which may cause a supply failure due to moisture absorption fixation of the powder or a concentration failure due to falling of the fixed lump.

  In addition, as a powder supply means, a load cell type weighing hopper is provided between the storage hopper and the dissolution tank, and the system that feeds back the weight of the powder received by this weighing hopper is known. It is necessary to provide a hopper specially, and there are problems such that the powder supply path and mechanism are complicated, and the powder easily adheres and scatters. Further, for example, in Patent Document 1, not a powder storage hopper, a plurality of containers containing powder are held in a container holding means and sequentially opened, and the powder is supplied from the opened container to the dissolution tank. However, the powder supply route and mechanism before the dissolution tank are complicated, and the powder tends to adhere particularly when the container is opened and when the powder is supplied from the opened container. There are problems such as becoming easier to scatter.

Japanese Patent No. 3965579

  Therefore, the object of the present invention is to pay attention to the problems in the conventional system as described above, and can supply powder in a short time, shorten the dissolution time, and can easily cope with a large central dialysis system. It is an object of the present invention to provide a dialysis powder solution dissolving method and apparatus that do not require accuracy, can simplify the entire apparatus, and can easily prevent adhesion and scattering of powder.

In the present invention, the entire amount of dialysis powder for batch processing is supplied to an empty dissolution tank or a dissolution tank in which a predetermined amount of dilution water is stored. Weigh in. Dilution water is supplied so as to have a predetermined mixing ratio corresponding to the supply amount of the measured powder for dialysis, and the supply amount is controlled by measuring the whole dissolution tank. In other words, when preparing a dialysis stock solution with a predetermined concentration by mixing dialysis powder and dilution water, the mixing ratio is uniquely determined by the target concentration, so the dialysis powder supplied first It is sufficient to add a predetermined ratio of dilution water to the supply amount of dialysis to prepare a dialysis stock solution having a predetermined concentration. In the preparation of the dialysis stock solution, the adjustment to the predetermined concentration is finally performed by controlling the supply amount of the dilution water. Therefore, the supply amount in the dialysis powder supply performed earlier is high. There is no need to control the accuracy, and a batch of powder for dialysis can be supplied to the dissolution tank in a short time, for example, at once, and the powder supply operation can be completed. Will not leave. The final adjustment of the concentration of the dialysis stock solution by supplying dilution water is performed by controlling the supply amount of water (diluted water). Therefore, compared to the conventional final adjustment of concentration by fine powder injection of powder, a simple supply amount control mechanism is achieved. Can be easily controlled, and high accuracy of the supply amount can be easily obtained. Therefore, the influence of residual powder in the conventional powder injection method, especially the occurrence of powder adhesion and scattering as described above, and poor concentration due to falling of the fixed mass, etc., can be prevented, and the entire device can be configured simply. However, adjustment to the target concentration of the dialysis stock solution can be performed with high accuracy within a short time.

  The dialysis powder solution dissolving apparatus according to the present invention includes a dialysis powder storage means for storing a dialysis powder, and a dialysis powder for supplying the dialysis powder in the dialysis powder storage means into a dissolution tank. By mixing and dissolving the supplied dialysis powder and dilution water at a predetermined mixing ratio, and a diluent supply means for supplying dilution water for diluting the dialysis powder into the dissolution tank. In a dialysis powder preparation dissolution apparatus having a dissolution tank for preparing a dialysis stock solution of a predetermined concentration, the supply amount of the dialysis powder supplied to the dissolution tank is measured together with the dissolution tank and then supplied to the dissolution tank. It comprises measuring means capable of measuring the diluted water together with the dissolution tank, and is configured such that the predetermined mixing ratio can be achieved through measurement by the measuring means.

  In the dialysis powder preparation dissolving apparatus according to the present invention, as described above, since the fine powder injection of the dialysis powder preparation is unnecessary, the dialysis powder preparation provided between the dialysis powder storage means and the dissolution tank. The supply means does not need a complicated mechanism as in the conventional fine powder injection means, and may be a simple mechanism means, so that the entire apparatus can be simplified, reduced in size, and reduced in cost. Further, since a relatively large amount of the dialysis powder may be supplied into the dissolution tank in a short time, the influence of residual powder in the apparatus by fine powder injection can be eliminated. And since the final concentration adjustment of the dialysis stock solution is performed by controlling the supply amount of dilution water, which is easier to control the supply amount than powder, the concentration can be adjusted with high accuracy while facilitating adjustment to a predetermined concentration. become. Therefore, compared to the conventional apparatus using fine powder injection, the entire apparatus can be configured simply while eliminating the influence of residual powder, and the concentration adjustment of the dialysis stock solution can be performed in a short time. become.

In the above-described dialysis powder solution dissolving apparatus according to the present invention, in order to make final fine adjustment to the predetermined mixing ratio, in addition to the dilution water supplied so far, the dilution water is added while measuring the supply amount. that having a dilution water additional supply means capable of supplying. This makes it possible to adjust the concentration of the dialysis stock solution with higher accuracy.

Further, dilution water added supply means for the final fine adjustment to the predetermined mixing ratio, ing from metering pump capable of feeding rate control of the dilution water with high accuracy. The metering pump as the diluting water additional supply means can be shared with, for example, a chemical solution supply metering pump for supplying a chemical solution into the dissolution tank.

According to dialysis powders soluble dismantlement location according to the present invention, does not take much time to supply the dialysis powder, and the supply of dilution water for concentration adjustment, and much more in comparison with the micronized Note Therefore, a dialysis stock solution having a predetermined concentration can be easily prepared with high accuracy in a short time. Moreover, since high precision is not required for supplying the dialysis powder, the powder supply means may be simple, and a relatively large amount of dialysis powder may be supplied to the dissolution tank in a short time. It is possible to prevent problems such as in the case of fine powder injection, simplify the entire device, reduce the size and reduce the cost, and achieve cleaning of the device and its surroundings, as well as maintenance and management work. Can be reduced. As a result, it is possible to provide an optimum dialysis powder soluble dismantlement location to correspond to the central dialysis system.

It is an equipment system diagram of a powder preparation dissolution device for dialysis concerning one embodiment of the present invention.

Hereinafter, preferred embodiments of the present invention will be described with reference to the drawings.
FIG. 1 shows a dialysis powder solution dissolving apparatus according to an embodiment of the present invention for carrying out a dialysis powder solution dissolving method according to an embodiment of the present invention. In FIG. 1, reference numeral 1 denotes the entire dialysis powder solution dissolving apparatus. The dialysis powder solution dissolution apparatus 1 is a dialysis powder storage means for storing a dialysis powder 2 by receiving the dialysis powder 2. A hopper 3, a feeder 4 as a dialysis powder supply means for supplying the dialysis powder in the hopper 3 into the dissolution tank, and a dilution water 5 for diluting the dialysis powder in the dissolution tank. A dilution water supply means 6 and a dissolution tank 7 for preparing a target dialysis stock solution having a predetermined concentration by mixing and dissolving the supplied dialysis powder and dilution water at a predetermined mixing ratio. Yes.

  In this embodiment, the dilution water 5 is supplied into the dissolution tank 7 via the dilution water supply valve 8 so that the final mixing ratio with the powder for dialysis can be controlled to a predetermined mixing ratio. In the final stage, the solution is supplied into the dissolution tank 7 via the final mixing ratio adjusting valve 9. Moreover, in this embodiment, the disinfecting liquid 10 as a chemical | medical solution can also be supplied in the dissolution tank 7. FIG. The disinfecting liquid 10 is supplied into the dissolution tank 7 through the disinfecting liquid supply valve 11, and the supply amount thereof can be controlled with high accuracy by the chemical liquid supplying quantitative pump 12. And in this embodiment, this chemical | medical solution supply metering pump 12 is a dilution for controlling the final supply amount of the dilution water supplied in the dissolution tank 7 via the final mixing ratio adjusting valve 9 with higher accuracy. It can also function as a metering pump for controlling the final water supply.

  The dissolution tank 7 weighs the supply amount of the powder for dialysis supplied to the dissolution tank 7 together with the dissolution tank 7, and measures the dilution water supplied to the dissolution tank 7 next to the measurement. It is provided on the mass measuring means 13 as a weighing means capable of doing. A predetermined mixing ratio of the powder for dialysis and the dilution water can be achieved through the measurement by the mass measuring means 13.

  Mixing of the powder for dialysis and the dilution water in the dissolution tank 7 is performed by, for example, mixed liquid circulation through the circulation pump 14 and the circulation valve 15. In this embodiment, in order to confirm whether or not the dialysis stock solution prepared by mixing is adjusted to a predetermined concentration, the conductivity can be measured as necessary. A branch circuit having a conductivity sensor 16 and a conductivity measuring circulation valve 17 is added. Furthermore, in this embodiment, in order to drain water from the dissolution tank 7 as necessary, a drain circuit provided with a drain valve 18 is connected to the lower part of the dissolution tank 7, and the drainage 19 is sent to an appropriate drainage destination. It is done. The stock solution for dialysis prepared to a predetermined concentration in the dissolution tank 7 is sent to the stock solution storage tank 21 through the transfer valve 20 using the circulation pump 14.

In the dialysis powder solution dissolving apparatus 1 configured as described above, the dialysis powder solution dissolving method according to the present invention is carried out as follows.
First, in the empty dissolution tank 7 or in the dissolution tank 7 in which a predetermined small amount of dilution water is stored (in this case, the small amount of dilution water stored is previously measured by the mass measuring means 13). The dialysis powder is supplied by the feeder 4 in an amount necessary for one batch processing. The supply of the powder for dialysis does not require highly accurate supply amount control, and the amount for one batch process may be supplied substantially at once in a short time. Therefore, compared to conventional fine powder injection, the supply time may be short, the powder supply operation is completed in a short time, and no powder is left in the powder injection port, as in the case of fine powder injection, Occurrence of poor density due to powder adhesion and scattering, and dropping of fixed mass is easily prevented.

  With the dialysis powder supplied in the dissolution tank 7, the supply amount of the dialysis powder is weighed by the mass measuring means 13 together with the dissolution tank 7. That is, at this stage, it is only necessary to grasp the supply result (that is, the supply amount) of the powder for dialysis. Dilution water is supplied so as to obtain a target predetermined mixing ratio corresponding to the supply amount of the measured powder for dialysis. The supply amount of the dilution water is also measured together with the dissolution tank 7, and the supply amount is controlled through the measurement. When preparing a dialysis stock solution with a predetermined concentration by mixing dialysis powder and dilution water, the mixing ratio of dialysis powder and dilution water is uniquely determined by the target concentration, so it was supplied first. A predetermined ratio of dilution water is added to the supply amount of the powder for dialysis. Since the control of the supply amount of the dilution water is the control of the supply amount of water, it can be performed extremely easily and with high accuracy as compared with the conventional mixing ratio adjustment by fine powder injection of powder. In addition, since both the supply amount of the dialysis powder and the supply amount of the dilution water are measured together with the dissolution tank 7, the final mixing ratio can be easily and accurately grasped, and the dialysis stock solution with a predetermined concentration can be accurately detected. To be prepared.

  Furthermore, in this embodiment, in order to make final fine adjustment to the predetermined mixing ratio, in addition to the dilution water supplied so far, the dilution water can be additionally supplied little by little while finally measuring the supply amount. Therefore, final fine adjustment can be easily performed with higher accuracy. In addition, since the metering pump 12 is used for the additional supply of dilution water for final fine adjustment, the concentration of the dialysis stock solution can be adjusted with higher accuracy. In addition, since the metering pump 12 is shared with the metering pump for supplying chemicals, it is possible to reduce the cost while simplifying the entire apparatus.

  As described above, in the dialysis powder preparation dissolving method and apparatus according to this embodiment, since the powder supply does not take time, the time required for the dissolution can be greatly reduced, and it is possible to cope with a large-scale central dialysis system. In addition, since fine powder injection is not required, the powder supply means does not require high accuracy, and since no powder intermediate weighing hopper is required, the powder supply mechanism can be configured simply, improving the degree of cleanliness and maintenance work. It is possible to reduce it.

  The present invention can be applied to any dialysis powder dissolution method and apparatus, and is particularly suitable for application to a central dialysis system.

DESCRIPTION OF SYMBOLS 1 Dialysis powder solution dissolution apparatus 2 Dialysis powder 3 Hopper as dialysis powder storage means 4 Feeder as dialysis powder supply means 5 Dilution water 6 Dilution water supply means 7 Dissolution tank 8 Dilution water supply valve 9 Final Mixing ratio adjusting valve 10 Disinfecting liquid 11 as chemical liquid Disinfecting liquid supply valve 12 Metering pump 14 for supplying chemical liquid Mass measuring means 14 as measuring means Circulating pump 15 Circulating valve 16 Conductivity sensor 17 Conductivity measuring circulating valve 18 Drain valve 19 Wastewater 20 Transfer valve 21 Stock solution storage tank

Claims (2)

Dialysis powder storage means for storing the dialysis powder, dialysis powder supply means for supplying the dialysis powder in the dialysis powder storage means into the dissolution tank, and diluting the dialysis powder. Dilution water supply means for supplying dilution water into the dissolution tank, and a dissolution tank for preparing a dialysis stock solution having a predetermined concentration by mixing and dissolving the supplied dialysis powder and dilution water at a predetermined mixing ratio; In the dialysis powder solution dissolver, the amount of dialysis powder supplied to the dissolution tank can be measured together with the dissolution tank, and then the dilution water supplied to the dissolution tank can be measured together with the dissolution tank. Dilution means supplied so far for final fine-tuning to the predetermined mixing ratio. In addition to water, dilute while measuring supply volume The additional supply can have a dilution water additional supply means, dialysis powder dissolving device to which the dilution water added supply means is characterized in that it consists of a metering pump. The powder preparation dissolution apparatus for dialysis according to claim 1 , wherein the metering pump as the dilution water additional supply means is shared with a chemical supply quantitative pump for supplying the chemical into the dissolution tank.

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