JP5336160B2 - Antibacterial composition - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide an antimicrobial agent composition exhibiting an excellent antimicrobial action on a textile product and a product having a hard surface. <P>SOLUTION: The antimicrobial agent composition includes a compound (A) represented by general formula (I), R-OH (wherein R is 8-14C straight-chain or branched-chain alkyl or alkenyl), a surfactant (B) and hypochlorous acid and/or a hypochlorite and/or a compound (C) releasing hypochlorous acid in water in the weight ratio of the component (A) to the component (B) of the weight of the component (A)/the weight of the component (B) of &le;2. <P>COPYRIGHT: (C)2010,JPO&amp;INPIT

Description

  The present invention relates to an antibacterial agent composition.

Even if textile products and products with hard surfaces around us are washed, for example, if they are textile products, odors will occur after a short time, and sinks, baths, washstands with hard surfaces, etc. In these areas and so on, slimy and nasty odors will be generated in less time. Many of these slimes and odors are derived from fungi, and even if you perform regular washing and washing activities, even if you use a detergent containing bleach or sterilizing ingredients, you will not be able to remove them sufficiently. Occur. Patent Document 1 discloses an antibacterial cleaning composition containing a bleaching agent and a nonionic surfactant, which is suitable for cleaning medical devices.
JP 2001-72996 A

  The slime and odor generated over time on textiles and hard surfaces are thought to be caused by chemical substances produced by metabolism in the process where fungi remain on the fiber surface, inside, or hard surface and proliferate. Conventionally, various surfactants are used against various soils. In Patent Document 1, it is considered that a surfactant is effective for removing dirt and a bleaching agent is effective for sterilizing bacteria floating in the washing water. It is considered that it is difficult to achieve an effect on fungi adhering to a product having a hard surface having a relatively complicated shape.

  An object of the present invention is to exhibit an excellent antibacterial action against fungi adhering to fibers in a fiber product or a relatively complicated part of a product having a hard surface in the washing process of a fiber product or a hard surface product. It is to provide an antibacterial composition.

The present invention relates to a compound (A) represented by the following general formula (I) [hereinafter referred to as component (A)], a surfactant (B) [hereinafter referred to as component (B)], and hypochlorous acid. Containing at least one compound (C) selected from hypochlorous acid and a compound that releases hypochlorous acid in water (hereinafter referred to as component (C)), component (A) and component (B) The weight ratio of (A) is 2 or less by weight of (A) component / (B) component.
R-OH (I)
(In the formula, R represents a linear or branched alkyl group or alkenyl group having 8 to 14 carbon atoms.)

  ADVANTAGE OF THE INVENTION According to this invention, the antimicrobial agent composition which can reduce the microbe which causes slime and odor, and shows the outstanding antimicrobial effect with respect to a textiles or a hard surface is provided.

<(A) component>
The component (A) is a compound represented by the above general formula (I), and the carbon number of R is preferably 8-14. R is preferably a straight chain among straight and branched chains. In this invention, it discovered that the outstanding antimicrobial effect was acquired by using (A) component and (B) component by specific ratio in presence of (C) component.

<(B) component>
Examples of the surfactant (B) used in the present invention include one or more selected from the group consisting of an anionic surfactant, a nonionic surfactant and an amphoteric surfactant. These surfactants can be used in combination of two or more.

  Although it does not specifically limit as an anionic surfactant, The following can be mentioned.

(1) Alkylbenzene sulfonates having a linear or branched alkyl group, wherein the alkyl group has an average carbon number of 8 to 18.

(2) An anionic surfactant having a polyoxyalkylene group, polyoxyalkylene ether sulfate, polyoxyalkylene alkenyl ether sulfate, polyoxyalkylene alkylaryl ether sulfate, polyoxyalkylene alkenyl aryl ether sulfate Salt, polyoxyalkylene mono- or dialkyl ether phosphate, polyoxyalkylene mono- or dialkenyl ether phosphate, polyoxyalkylene mono- or diphenyl ether phosphate, polyoxyalkylene alkyl ether carboxylate, polyoxyalkylene Alkenyl ether carboxylate, polyoxyalkylene alkyl ether acetate, polyoxyalkylene alkenyl ether acetate, polyoxyalkylene alkyl amide ether catalyst Bonn salts, polyoxyalkylene alkenyl ether carboxylic acid salts and the like.

  As the alkyl group or alkenyl group in these anionic surfactants, those having 4 to 26 carbon atoms are preferred, and those having 8 to 24 carbon atoms are particularly preferred. These alkyl groups or alkenyl groups may be linear or branched. In addition, examples of the polyoxyalkylene group in the anionic surfactant include a polyoxyethylene group, a polyoxypropylene group, and a polyoxybutylene group, and a polyoxyethylene group and a polyoxypropylene group are preferable. Moreover, the number of added moles of the polyoxyalkylene group is preferably 1 to 20, and particularly preferably 1 to 10. Furthermore, as the salt in the anionic surfactant, alkali metal salts such as sodium and potassium, alkaline earth metal salts such as calcium and magnesium, ammonium salts, alkanolamines such as mono-, di- and triethanolamine Etc.

(3) Alkyl or alkenyl sulfate, wherein the alkyl group or alkenyl group has an average carbon number of 8 to 20.

(4) Olefin sulfonates having an average of 10 to 20 carbon atoms.

(5) Alkane sulfonates having an average of 10 to 20 carbon atoms.

(6) Saturated or unsaturated fatty acid salts having an average of 10 to 24 carbon atoms.

(7) α-sulfo fatty acid salts or α-sulfo fatty acid esters represented by the following general formula (II):

[Wherein Y represents an alkyl group having 1 to 3 carbon atoms or a counter ion, Z represents a counter ion, and R ¹ represents an alkyl group or alkenyl group having 10 to 20 carbon atoms. ]
Examples of the counter ion of the anionic surfactant include alkali metal ions such as sodium and potassium.

(8) A diphenyl ether disulfonic acid type anionic surfactant represented by the general formula (III).

[Wherein R ² and R ³ represent a linear or branched alkyl group or alkenyl group having 6 to 22 carbon atoms or a hydrogen atom (provided that R ² and R ³ are both hydrogen atoms) And M and M ′ represent a hydrogen atom, an alkali metal, an ammonium group, or an alkanol-substituted ammonium group]

  Among the above-mentioned anionic surfactants, (1), (2), (3), (6) and (8) are preferable from the viewpoints of detergency and finish after washing. Among (2), polyoxyalkylene alkyl ether sulfate, polyoxyalkylene alkenyl ether sulfate, polyoxyalkylene alkyl ether acetate, polyoxyalkylene alkenyl ether acetate, polyoxyalkylene alkylamide ether carboxylate, Polyoxyalkylene alkenyl amide ether carboxylates are particularly preferred. Here, examples of the polyoxyalkylene alkyl amide ether carboxylate and the polyoxyalkylene alkenyl amide ether carboxylate include amide ether carboxylates represented by the following general formula (IV).

[Wherein, R ⁴ represents a linear or branched alkyl group or alkenyl group having 5 to 21 carbon atoms, x and y each independently represent an average addition mole number of 0 to 20, and 1 ≦ x + y ≦ 20, and A is (C ₂ H ₄ O) _k (C ₃ H ₆ O) _j CH ₂ COOM, (C ₂ H ₄ O) _k (C ₃ H ₆ O) _j CH ₂ CH ₂ OH, A hydrogen atom or an alkyl group having 1 to 3 carbon atoms, k and j each independently have an average addition mole number of 0 to 20 and 0 ≦ k + j ≦ 20, and M and M ′ are alkali metals , An alkaline earth metal, an ammonium group or an alkanol-substituted ammonium group. ]

In addition, the above amide ether carboxylate may contain a slight amount of a compound that is a production intermediate and does not have —CH ₂ COOM added to the general formula (IV). May be used.

  More preferable examples of the anionic surfactant include polyoxyethylene (ethylene oxide average addition mole number 1 to 10) alkyl (carbon number 8 to 24) ether sulfate, polyoxyethylene (ethylene oxide average addition mole number 1). -10) alkyl (carbon number 8 to 24) ether acetate, polyoxyethylene (ethylene oxide average addition mole number 1 to 10) alkyl (carbon number 8 to 24) amide ether carboxylate, alkyl (carbon number 8 to 20) ) Sulfates can be mentioned.

  Although it does not specifically limit as a nonionic surfactant, Polyoxyethylene alkyl or alkenyl ether, polyoxyethylene alkyl phenyl ether, polyoxypropylene alkyl or alkenyl ether, polyoxybutylene alkyl or alkenyl ether, alkylene oxide addition alkyl group or Alkenyl group-containing nonionic surfactant mixture, sucrose fatty acid ester, aliphatic alkanolamide, fatty acid glycerin monoester, polyglycerin fatty acid ester, polyoxyethylene sorbitan fatty acid ester, ethylene oxide condensed surfactant and alkyl glycoside 1 type or 2 types or more selected are preferable. Specific examples of such a nonionic surfactant include the following (1) to (11).

(1) Polyoxyethylene alkyl or alkenyl ethers having an alkyl group or alkenyl group having an average carbon number of 10 to 20 and an average number of moles of ethylene oxide added of 1 to 30 mol.

(2) Polyoxyethylene alkylphenyl ethers having an alkyl group having an average carbon number of 6 to 12 and an average number of moles of ethylene oxide added of 1 to 25 mol.

(3) Polyoxypropylene alkyls or alkenyl ethers having an alkyl group or alkenyl group having an average carbon number of 10 to 20, and an average number of moles of propylene oxide added of 1 to 20 moles.

(4) Polyoxybutylene alkyls or alkenyl ethers, wherein the alkyl group or alkenyl group has an average carbon number of 10 to 20, and the number of moles of butylene oxide added is 1 to 20 mol on average.

(5) It has an alkyl group or an alkenyl group, and ethylene oxide and propylene oxide (molar ratio: 0.1 / 9.9 to 9.9 / 0.1) and / or ethylene oxide and butylene oxide (molar ratio: 0.00). 1 / 9.9 to 9.9 / 0.1) is added, and the average carbon number of the alkyl group or alkenyl group is 10 to 20, and per one molecule The total added mole number of alkylene oxide is 1 to 30 moles on average.

(6) Higher fatty acid alkanolamides represented by the following general formula (V) or alkylene oxide adducts thereof.

[Wherein, R ⁵ represents an alkyl group or alkenyl group having 10 to 20 carbon atoms, R ⁶ and R ⁷ represent the same or different hydrogen atoms or CH ₃ , p is a number of 1 to 3, q is 0 to 0, The number of 3 is shown. ]

(7) Sucrose fatty acid esters, wherein the fatty acid moiety has an average carbon number of 10-20.

(8) Polyglycerol fatty acid esters and fatty acid glycerol monoesters, wherein the fatty acid moiety has an average carbon number of 10 to 20, and the glycerol unit is 1 to 20.

(9) A nonionic surfactant having a trade name of “Pluronic” (Asahi Denka Co., Ltd.) obtained by condensing ethylene oxide and propylene oxide.

(10) Alkyl polysaccharides. For example, an alkyl polysaccharide represented by the following general formula (VI).
R ⁸ (OR ⁹ ) _x1 G _y1 (VI)
[Wherein R ⁸ represents a linear or branched alkyl group having 8 to 18 carbon atoms in total, an alkenyl group or an alkylphenyl group, R ⁹ represents an alkylene group having 2 to 4 carbon atoms, and G represents carbon. The residue derived from the reducing sugar which has number 5-6 is shown, x1 (average value) shows 0-5, y1 (average value) shows 1-5. ]

  The average value of x1 in the formula (VI) is 0 to 5, but by changing this value, the water solubility and crystallinity of the cleaning composition can be adjusted. That is, the larger the value of x1, the higher the water solubility and the lower the crystallinity. A preferable value of x1 is 0 to 2, particularly preferably 0.

  In the formula (VI), when y1 has an average value larger than 1, that is, when a sugar chain of 2 or more sugars is used as a hydrophilic group, the binding mode of the sugar chain is 1-2, 1-3, 1-4. , 1-6 linkages, as well as α-, β-pyranoside linkages or furanoside linkages and any mixtures having these mixed modes of binding. Moreover, the average value of y1 in general formula (VI) is 1-5, Preferably it is 1-1.5, More preferably, it is 1.1-1.4. In addition, the measured value of y1 is based on a proton NMR method.

R ⁸ in formula (VI) is preferably an alkyl group having 10 to 14 carbon atoms from the viewpoint of solubility and detergency. R ⁹ is preferably an alkylene group having 2 to 3 carbon atoms from the viewpoint of water solubility.

  The structure of G in the formula (VI) is determined by the raw material of monosaccharide or disaccharide or more. As the raw material of G, glucose, fructose, galactose, xylose, mannose, lyxose, arabinose, sorbitan Sorbitol and a mixture thereof, and may include maltose, xylobiose, isomaltose, cellobiose, gentibiose, lactose, sucrose, nigerose, tulanose, raffinose, gentianose, merezitose and a mixture thereof. it can. Among these, preferable raw materials are glucose and fructose for monosaccharides and maltose and sucrose for disaccharides or more from the viewpoint of availability and cost. Among these, glucose is particularly preferable from the viewpoint of easy availability.

  Furthermore, the following general formula (VII)

[Wherein R ¹⁰ is an alkyl group having 6 to 24 carbon atoms. ]
1 mol adduct of pentaerythritol and isostearyl glycidyl ether, 1 mol adduct of sorbitol and isostearyl glycidyl ether, 1 mol adduct of mannitol and 2-octyldodecyl glycidyl ether, methyl glucoside 1 mol adduct of isostearyl glycidyl ether, 1 mol adduct of diglycerinisostearyl glycidyl ether, phytantriol, etc., and at least 1 long-chain branched alkyl group or alkenyl group and at least 3 Nonionic surfactants having a hydroxyl group can be mentioned.

  Among these nonionic surfactants, the nonionic surfactants (1), (8), and (10) are preferable, and the nonionic surfactants (1) and (10) are particularly preferable.

  Although it does not specifically limit as an amphoteric surfactant, 1 type, or 2 or more types chosen from amine oxides and betaines can be mentioned.

(1) Amine oxides. For example, the alkyl or alkenylamine oxide which has a C1-C24 linear or branched alkyl group or alkenyl group can be mentioned. More preferable amine oxides include alkylamine oxides represented by the following general formula (VIII).

[Wherein R ¹¹ represents an alkyl group or alkenyl group having 8 to 24 carbon atoms, R ¹² and R ¹³ represent the same or different alkyl groups having 1 to 3 carbon atoms, and D represents —NHC (═O) — A group or —C (═O) NH— group, E represents an alkylene group having 1 to 5 carbon atoms, a and b represent a = 0 and b = 0 or a = 1 and b = 1. ]

In the general formula (VII), R ¹¹ is an alkyl group or alkenyl group having 8 to 24 carbon atoms, and an alkyl group having 12 to 18 carbon atoms is particularly preferable. R ¹² and R ¹³ are each an alkyl group having 1 to 3 carbon atoms, and a methyl group having 1 carbon atom is particularly preferable.

(2) Betaines. In this invention, the 1 type (s) or 2 or more types chosen from the betaines represented by the following general formula (IX), (X), (XI) and (XII) can be mentioned.

[Wherein, R ¹⁴ represents a linear or branched alkyl group or alkenyl group having 8 to 22 carbon atoms, and R ¹⁵ and R ¹⁶ may be the same or different and may be substituted with a hydroxyl group. R ¹⁷ represents a linear or branched alkyl group or alkenyl group having 7 to ²¹ carbon atoms, Y represents a hydrogen atom or a hydroxyl group, and r, s, and t each represent a number of 1 to 3. U represents a number of 1 to 5, v represents a number of 1 or more, and w and x represent numbers satisfying 0 ≦ w + x ≦ 4. ]

In the general formula (IX), R ¹⁴ is preferably a saturated alkyl group having 8 to 18 carbon atoms in terms of detergency, particularly preferably a saturated alkyl group having 10 to 16 carbon atoms. For the same reason, R ¹⁵ and R ¹⁶ are each preferably a methyl group, an ethyl group or a hydroxyethyl group, and r is preferably 1.

In the general formula (X), R ¹⁴ is preferably a saturated alkyl group having 8 to 18 carbon atoms in terms of detergency, particularly preferably a saturated alkyl group having 10 to 16 carbon atoms. For the same reason, R ¹⁵ and R ¹⁶ are each preferably a methyl group, an ethyl group or a hydroxyethyl group, s is preferably 1, and t is preferably 1.

In the general formulas (XI) and (XII), R ¹⁷ is preferably a saturated alkyl group having 9 to 15 carbon atoms in terms of detergency. For the same reason, R ¹⁵ and R ¹⁶ are each preferably a methyl group, an ethyl group or a hydroxyethyl group, u is preferably 2 or 3, v is preferably 1, w is preferably 1, and x is preferably 1. Specific examples thereof include alkylamidopropyl-N, N-dimethylacetic acid betaine, alkylamidopropyl-N, N-dimethyl-2-hydroxypropylsulfobetaine, alkylamidopropyl-N, N-dimethyl-propylsulfobetaine, and the like. Can be mentioned. Among these, in terms of detergency and foaming power, lauric acid amidopropyl-N, N-dimethylacetic acid betaine, myristic acid amidopropyl-N, N-dimethylacetic acid betaine, cocamidoamidopropyl-N, N-dimethyl Preferred are betaine acetate, lauryl hydroxysulfo betaine, amidopropyl laurate-N, N-dimethyl-2-hydroxypropyl betaine, and the like.

  Among these amphoteric surfactants, the amphoteric surfactant (1) is preferable.

  As the component (B), nonionic surfactants and anionic surfactants are preferable from the viewpoint of detergency, and nonionic surfactants are particularly preferable.

<(C) component>
The component (C) of the present invention is one or more compounds selected from hypochlorous acid, hypochlorite, and compounds that release hypochlorous acid in water. Examples of hypochlorite include alkali metal salts such as sodium salt and potassium salt, among which sodium salt is preferable. A compound that releases hypochlorous acid in water includes dichloroisocyanuric acid. (C) As a component, hypochlorite and also sodium hypochlorite are preferable.

<Antimicrobial agent composition>
In the antibacterial agent composition of the present invention, the weight ratio of the component (A) to the component (B) is 2 or less in terms of the weight of the component (A) / the weight of the component (B). Preferably it is 0.01-2, More preferably, it is 0.05-2, More preferably, it is 0.05-1, Most preferably, it is 0.05-0.5. An excellent antibacterial effect is obtained within this range.

  As described above, the component (A) can be present in the polyoxyethylene alkyl or alkenyl ether which is the nonionic surfactant of the component (B), but the component (A) is included as the component (B). When a nonionic surfactant is used, a compound corresponding to the component (A) in the nonionic surfactant is handled as the component (A). Therefore, the weight ratio of the compound corresponding to the component (A) in the polyoxyethylene alkyl or alkenyl ether and the weight ratio of the other compounds satisfy the weight ratio of the components (A) and (B). A thing can be used as it is as a mixture of (A) component and (B) component.

  After satisfying the above weight ratio, the antibacterial agent composition of the present invention comprises (A) component in an amount of 0.01 to 10% by weight, further 0.1 to 10% by weight, and further 0.5 to 5% by weight It is preferable to contain. Moreover, it is preferable to contain (B) component 0.01 to 30 weight%, Furthermore, 0.01 to 20 weight%, Furthermore, 1 to 20 weight% is contained. Moreover, it is preferable to contain (C) component 0.1 to 10 weight% as hypochlorous acid, Furthermore, 0.01 to 5 weight%, Furthermore, 0.5 to 5 weight% is contained.

  The weight ratio of the component (A) to the component (C) (but as hypochlorous acid) is preferably 0.01 to 1 in terms of the weight of the component (A) / the weight of the component (C), and more preferably 0.02. To 1, more preferably 0.03 to 1.

  The antibacterial agent composition of the present invention can be used in a powder state in which the components (A) to (C) are mixed, in a molded pellet state, or in a paste state, but preferably a liquid composition further containing water as a balance, preferably It can be an aqueous solution. In view of storage stability, ion-exchanged water or distilled water from which metal ions and the like that are present in a trace amount are removed is preferable. In the case of a liquid composition, the content of water is preferably 50 to 99% by weight, more preferably 70 to 99% by weight in the antibacterial agent composition.

  The antibacterial agent composition of the present invention can contain the following components in addition to the components (A) to (C).

  Other antibacterial agents and antibacterial agents can be used in combination with the antibacterial agent composition of the present invention. On textile products and hard surfaces, the fungicide may not be effective due to secretions produced by fungi. The antibacterial agent composition of the present invention exhibits the effect of the component (A) sufficiently by washing or suppressing production of such secretions, and is excellent even when other antibacterial agents and antibacterial agents are used in combination. Sterilization, antibacterial effect can be obtained.

  The above bactericides and antibacterials include benzalkonium chloride, benzethonium chloride, didecyldimethylammonium chloride, cetylpyridinium chloride, chlorhexidine hydrochloride, chlorhexidine gluconate, polyhexamethylenebiguanidine hydrochloride, triclosan, isopropyl Examples include methylphenol, trichlorocarbanilide, ethanol, isopropyl alcohol and the like.

  In the antibacterial agent composition of the present invention, it is also possible to use a thickener in order to increase the viscosity and improve the adhesion to an object.

  Further, a chelating agent may be added to the antibacterial agent composition of the present invention. Examples of the chelating agent include ethylenediaminetetraacetic acid (EDTA), succinic acid, salicylic acid, oxalic acid, malic acid, lactic acid, fumaric acid, tartaric acid, citric acid, gluconic acid, tripolyphosphoric acid, 1-hydroxyethane-1,1-diphosphone. Examples include acids, polyacrylic acid, acrylic acid / maleic acid copolymers, and salts thereof.

  The antibacterial agent composition of the present invention is preferably used as an aqueous solution, that is, an aqueous composition. In an aqueous composition, it is preferable to make it the aqueous solution whose weight concentration of (A) component is 0.1 to 10 weight%.

  The pH at 20 ° C. of the aqueous antibacterial agent composition of the present invention is preferably 6 to 14, and more preferably 8 to 13.5. The pH of the aqueous antibacterial agent composition of the present invention can be measured by using the composition at 20 ° C. using a pH meter F52 manufactured by Horiba, Ltd. and a pH electrode 6367-S004. The pH of the composition can be adjusted using a pH adjuster. As the pH adjuster, hydrochloric acid, sulfuric acid, phosphoric acid, organic acid or the like can be used as an acid agent, and sodium hydroxide, potassium hydroxide, sodium carbonate, potassium carbonate or the like can be used as an alkali agent.

  The viscosity at 20 ° C. of the aqueous antibacterial agent composition of the present invention is preferably 3 to 100 mPa · s, more preferably 3 to 50 mPa · s. The viscosity of the aqueous antibacterial composition of the present invention is such that the composition at 20 ° C. is manufactured by Tokyo Keiki Co., Ltd. B-type viscometer (type BM), rotor No. 1 can be used for measurement. The viscosity of the composition can be adjusted by appropriately setting the weight concentration of the component (A) in the range of 0.1 to 10% by weight.

  The antibacterial agent composition of the present invention is suitable for hard surfaces and textile products. Hard surfaces include fixed objects such as plastic, rubber, metal, tile, brick, concrete, cement, glass, wood, etc., staircases, walls, etc., as well as various instruments, instruments, tools, furniture, tableware, etc. Hard surfaces in general in contact with humans. For example, it can be applied to hard surfaces such as toilets, baths, washstands, and kitchens. The antibacterial agent composition of the present invention includes an antibacterial agent for kitchens, an antibacterial agent for bathrooms, an antibacterial agent for floors, an antibacterial agent for tableware, an antibacterial agent for a fully automatic washing machine washing tub, an antibacterial agent for a drain pipe, a kitchen and a bathroom. It can be used as an antibacterial agent for small items. Further, in the case of textile products, the present invention can be applied to various textile products (including products that partially include fibers) such as clothing, bedding, shoes including fabrics, and cloth-making bags including fabrics.

The antibacterial agent composition of the present invention is used in contact with an object by spraying, coating, dipping, or the like. The method of using the antibacterial agent composition of the present invention is as follows: (1) A method of spraying a composition or a diluted composition obtained by diluting the composition with water using a sprayer (sprayer) such as a trigger onto an object (2 ) A method of impregnating a water-absorbing flexible material with a composition or a diluted composition obtained by diluting the composition with water, and rubbing the target; and (3) a target obtained by diluting the composition or the composition with water. A method of immersing an object is preferable, and the method (1) is particularly preferable from the viewpoint of simplicity. Thereby, the antimicrobial agent with a container formed by filling the antimicrobial agent composition of this invention into a spray container is obtained. The spray amount is preferably, for example, a ratio of 0.5 to 5 g with respect to the object 1 m ² .

  It is effective to use the antibacterial agent composition of the present invention as a diluted composition (water diluted solution) diluted with water. A predetermined amount of the diluted solution of water in the composition is accumulated and used by immersing the object. When the object covers a wide range, the mist may be sprayed using a spray device, or the foamed material may be sprayed using a foaming machine. Further, the composition may be applied by pouring a water-diluted solution or brushing. Alternatively, the object may be wiped off by impregnating the towel with a water-diluted solution. If the conditions for contact with microorganisms are satisfied, it is possible to attach or apply a water dilution of the composition to the surface where microorganisms may be present. In the water dilution of the composition, the weight concentration of the component (A) when used is preferably 1 to 10,000 ppm, more preferably 5 to 10,000 ppm. Therefore, the present invention provides an antibacterial method in which the water-diluted solution of the antibacterial agent composition of the present invention is brought into contact with a hard surface or a fiber product (usually microorganisms are present on these surfaces).

<Ingredients used>
[1] Component (A-1): Alcohol having 8 carbon atoms [Calcal 0898, manufactured by Kao Corporation, R is a compound having an alkyl group having 8 carbon atoms in general formula (I)]
(A-2): Alcohol having 10 carbons [Calcoal 1098, manufactured by Kao Corporation, compound of general formula (I), wherein R is an alkyl group having 10 carbons]
(A-3): Alcohol having 12 carbons [Calcoal 2098, manufactured by Kao Corporation, in general formula (I), R is a compound having an alkyl group having 12 carbons]
(A-4): C14 alcohol [Calcoal 4098, manufactured by Kao Corporation, in general formula (I), R is a compound having a C14 alkyl group]
(A-5): C12 unsaturated alcohol [trans-2-dodecen-1-ol, manufactured by Wako Pure Chemical Industries, Ltd., in general formula (I), wherein R is a alkenyl group compound having 12 carbons ]
(A-6): C12 alcohol (secondary) [2-dodecanol, Wako Pure Chemical Industries, Ltd., general formula (I), wherein R is a C12 alkyl group (secondary) compound]
(A-7): C12 branched chain alcohol [2-butyl-1-octanol, Sigma-Aldrich Inc. Manufactured, compound of general formula (I), wherein R is a branched alkyl group having 12 carbon atoms]
(A′-8): C 4 alcohol [1-butanol, manufactured by Wako Pure Chemical Industries, Ltd., in general formula (I), R is a compound having a C 4 alkyl group]
(A′-9): Alcohol having 16 carbon atoms [Calcoal 6098, manufactured by Kao Corporation, in general formula (I), R is a compound having an alkyl group having 16 carbon atoms]

[2] Component (B) <Anionic surfactant>
(B-1): Sodium lauryl sulfate [Emar 0, manufactured by Kao Corporation]
(B-2): Polyoxyethylene (2) sodium lauryl ether sulfate [Emar 20C, manufactured by Kao Corporation; effective content 25% by weight]
(B-3): Polyoxyethylene (4.5) sodium lauryl ether acetate [Kao Akipo RLM45-NV, manufactured by Kao Corporation; effective 24% by weight]
<Nonionic surfactant>
(B-4): Polyoxyethylene (6) lauryl ether [Emulgen 106, manufactured by Kao Corporation]
(B-5): Polyoxyethylene (12) lauryl ether [Emulgen 120, manufactured by Kao Corporation]
(B-6): Lauryl glucoside [Mydoll 12, manufactured by Kao Corporation]
(B-7): Decylglycerin monocaprylate [SY Glister MCA750, manufactured by Sakamoto Pharmaceutical Co., Ltd.]
(B-8): Sorbitan monolaurate [Leodol SP-L10, manufactured by Kao Corporation]
(B-9): Polyoxyethylene (6) sorbitan monolaurate [Leodol TW-L106, manufactured by Kao Corporation]
(B-10): Polyoxyethylene (20) sorbitan monolaurate [Leodol TW-L120, manufactured by Kao Corporation]
In addition, the number in () shows an ethylene oxide average addition mole number. The table also shows the effective amount.

[3] Component (C) Sodium hypochlorite; manufactured by Nankai Chemical Industry Co., Ltd.

<Evaluation>
[1] Preparation of antibacterial agent solution (evaluation sample) The antibacterial agent compositions shown in Tables 1 and 2 were prepared so that the component (A) was 100 ppm. And diluted with water to prepare an antibacterial agent solution. Each antibacterial agent composition (stock solution) had a pH of 12 to 13 at 20 ° C. and a viscosity of 3 to 20 mPa · s at 20 ° C. In the table, (a) / (B) weight ratio is shown with (a′-8) and (a′-9) as the component (A).

[2] Preparation of Bacterial Solution Using Pseudomonas aeruginosa NBRC13275, soybean-Casein Digest Agar (SCD agar medium: Nippon Pharmaceutical Co., Ltd.) A very small amount of the bacterial mass from the colony formed by pre-culture for an hour is put into sterile physiological saline using a sterilized disposable loop (manufactured by AS ONE Corp., type 10), and becomes approximately 10 ⁵ cfu / 50 μl. The thing adjusted so was prepared.

[3] Disinfection test with textile products In a 50 ml sterilized centrifuge tube container, 200 μl of the liquid medium was dropped onto a sterilized knitted cloth (3 cm × 3 cm), and then 50 μl of the bacterial solution was dropped and cultured at 37 ° C. for 24 hours. . Thereafter, the prepared antibacterial agent solution is sprayed in a spray vial (No. 6 manufactured by Maruemu Co., Ltd.) with a discharge amount of 0.02 g and left to stand for 10 minutes. Then, 20 ml LP diluted solution is put in the centrifuge tube, and the bacteria are extracted from the cloth by stirring with a stirrer for 1 minute. The extract was appropriately diluted, inoculated on the same agar medium as described above, cultured at 37 ° C. for 24 hours, counted for the number of bacteria, and compared with the number of bacteria in the untreated sample. The treated cloth was extracted again with the LP solution to confirm that no bacteria remained. The sterilization performance was evaluated according to the following criteria. In the following evaluation criteria, 2 is judged to have a sterilizing effect, and 1 has the highest sterilizing effect.

Evaluation criteria for sterilization performance 1: The number of bacteria decreased by 10 ³ or more compared to the untreated sample 2: The number of bacteria decreased by 10 ² or more and less than 10 ³ compared to the untreated sample 3: The number of bacteria compared to the untreated sample Is less than 10 ²

[4] Sterilization test on hard surface On a 50 ml sterile centrifuge tube surface (hard surface), 200 μl of liquid medium is dropped, and then 50 μl of bacterial liquid is dropped and cultured at 37 ° C. for 24 hours. Thereafter, the prepared antibacterial agent solution is sprayed at a discharge amount of 0.1 g in a spray vial (manufactured by Maruemu Co., Ltd., No. 6) and allowed to stand for 10 minutes. Then, add 20 ml LP diluent to the centrifuge tube, stir with a stirrer for 1 minute, dilute appropriately, inoculate the same agar medium as above, incubate at 37 ° C for 24 hours, count the number of bacteria, untreated sample And compared. The sterilization performance was evaluated according to the following criteria. In the following evaluation criteria, 2 is judged to have a sterilizing effect, and 1 has the highest sterilizing effect.

Evaluation criteria for sterilization performance 1: The number of bacteria decreased by 10 ³ or more compared to the untreated sample 2: The number of bacteria decreased by 10 ² or more and less than 10 ³ compared to the untreated sample 3: The number of bacteria compared to the untreated sample Is less than 10 ²

[5] Discoloration test for textile products Prepare a two-tank washing machine (Toshiba Galaxy 3.6 VH-360S1), put 40 liters of 20 ° C tap water into the washing tub, and make 1.4 kg of cotton Of underwear and 0.6 kg of cotton / polyester unweared shirt. Prepare one piece of 30cm x 30cm cotton cloth with 5 pieces sewn at the center and four corners of the test cloth (black T-shirt (made by UNIQLO CO., LTD.) Cut into 10cm x 10cm). The test cloth was sprayed to 1 g / sheet of antibacterial agent solution and allowed to stand for 10 minutes, then placed in a washing tub and attack (powder type) Lot. Put W153137 in standard working concentration and wash normally for 10 minutes. Then dehydrate for 1 minute and repeat rinse twice for 4 minutes. Then dehydrate for 5 minutes and let it air dry indoors. This process was regarded as one process, and cumulative cleaning was performed 5 times. For colorimetry, the L value, a value, and b value are measured using a color difference meter (Nippon Denshoku Industries Co., Ltd .: ND (F) -300A), the ΔE value is obtained by the following formula, and evaluated according to the following criteria: did. It means that the smaller the ΔE value, the less discoloration color in the cumulative cleaning. When the ΔE value is greater than 2, fading can be confirmed by visual observation.
ΔE = {(ΔL) ² + (Δa) ² + (Δb) ² } ^1/2
ΔL; (L value of the cloth after washing) − (L value of the cloth before washing)
Δa; (a value of cloth after washing) − (a value of cloth before washing)
Δb; (b value of the cloth after washing) − (b value of the cloth before washing)
Evaluation criteria 1: ΔE value is 2 or less 2: ΔE value is greater than 2

[6] Discoloration test of hard surface JISG4305 (SUS316) manufactured by Nippon Test Panel Co., Ltd. was used as the test piece for the discoloration test. The antibacterial agent solution was sprayed on SUS316 at a rate of 1 g / times in the spray vial and allowed to stand for 10 minutes. Then rinsed with tap water and wiped with a dry cloth. This process was repeated 30 times, and the discoloration color was visually observed and judged according to the following criteria. In the following evaluation criteria, it is determined that 2 is a level at which quality problems occur, and 1 is determined that such problems do not occur.
Evaluation criteria 1: No discoloration 2: Dullness or discoloration is observed

Claims (5)

Compound (A) represented by the following general formula (I) [hereinafter referred to as component (A)], surfactant (B) [hereinafter referred to as component (B)], hypochlorous acid, hypochlorous acid Containing at least one compound (C) selected from compounds that release hypochlorous acid in acid salts and water (hereinafter referred to as component (C)), wherein the weight ratio of component (A) to component (B) is The antibacterial agent composition which is 2 or less by weight of the component (A) / weight of the component (B).
R-OH (I)
(Wherein, R represents an alkyl or alkenyl group of a straight chain of 8 to 14 carbon atoms.) The antibacterial agent composition according to claim 1 , wherein component (A) is a compound in which R in general formula (I) is a linear alkyl group or alkenyl group having 10 to 12 carbon atoms . The antibacterial composition according to claim 1 or 2 , wherein the component (B) is at least one selected from the group consisting of an anionic surfactant, a nonionic surfactant, and an amphoteric surfactant. The antibacterial agent composition according to any one of claims 1 to 3, comprising 0.1 to 10% by weight of component (A) and 0.1 to 10% by weight of component (C) as hypochlorous acid. The weight ratio of (A) component (C) (except as hypochlorous acid), from 0.01 to 1 by weight of the weight / the component (C) of the component (A), according to claim 1-4 The antibacterial agent composition of any one of Claims.