JP5306986B2 - Ｐ２ｘ７調節因子としてのビシクロへテロアリール化合物およびその使用 - Google Patents
Ｐ２ｘ７調節因子としてのビシクロへテロアリール化合物およびその使用 Download PDFInfo
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- JP5306986B2 JP5306986B2 JP2009500517A JP2009500517A JP5306986B2 JP 5306986 B2 JP5306986 B2 JP 5306986B2 JP 2009500517 A JP2009500517 A JP 2009500517A JP 2009500517 A JP2009500517 A JP 2009500517A JP 5306986 B2 JP5306986 B2 JP 5306986B2
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| WO2009132136A1 (en) * | 2008-04-23 | 2009-10-29 | Rigel Pharmaceuticals, Inc. | Carboxamide compounds for the treatment of metabolic disorders |
| BRPI0921299A2 (pt) | 2008-11-21 | 2015-08-25 | High Point Pharmaceuticals Llc | Compostos de benzamida adamantila |
| DK2243772T3 (da) | 2009-04-14 | 2012-02-13 | Affectis Pharmaceuticals Ag | Hidtil ukendte P2X7R-antagonister og deres anvendelse |
| EP2386541A1 (en) | 2010-05-14 | 2011-11-16 | Affectis Pharmaceuticals AG | Novel methods for the preparation of P2X7R antagonists |
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| MX2014000894A (es) | 2011-07-22 | 2014-02-27 | Actelion Pharmaceuticals Ltd | Derivados de amidas heterociclicas como antagonistas de receptores p2x7. |
| TWI576347B (zh) | 2012-01-20 | 2017-04-01 | 艾克泰聯製藥有限公司 | 作為ｐ２ｘ受體拮抗劑之雜環醯胺衍生物 |
| KR102232742B1 (ko) | 2012-12-12 | 2021-03-26 | 이도르시아 파마슈티컬스 리미티드 | Ｐ２ｘ７ 수용체 길항제로서의 인돌 카르복사미드 유도체 |
| WO2014097140A1 (en) | 2012-12-18 | 2014-06-26 | Actelion Pharmaceuticals Ltd | Indole carboxamide derivatives as p2x7 receptor antagonists |
| JP6282016B2 (ja) | 2013-01-22 | 2018-02-21 | イドーシア ファーマシューティカルズ リミテッドＩｄｏｒｓｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ | Ｐ２ｘ７受容体アンタゴニストとしての複素環アミド誘導体 |
| JP6282017B2 (ja) | 2013-01-22 | 2018-02-21 | イドーシア ファーマシューティカルズ リミテッドＩｄｏｒｓｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ | Ｐ２ｘ７受容体アンタゴニストとしての複素環アミド誘導体 |
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| US20060223849A1 (en) | 2005-03-14 | 2006-10-05 | Mjalli Adnan M | Benzazole derivatives, compositions, and methods of use as beta-secretase inhibitors |
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| JP2009507855A (ja) | 2005-09-08 | 2009-02-26 | スミスクライン・ビーチャム・コーポレイション | 非環式１，４−ジアミンおよびその使用 |
| TWI412322B (zh) | 2005-12-30 | 2013-10-21 | 杜邦股份有限公司 | 控制無脊椎害蟲之異唑啉 |
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| EP1937643A2 (en) | 2008-07-02 |
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| MX2008011919A (es) | 2008-11-28 |
| WO2007109160A3 (en) | 2008-05-02 |
| US20110118287A1 (en) | 2011-05-19 |
| WO2007109160A9 (en) | 2007-11-15 |
| US8779144B2 (en) | 2014-07-15 |
| JP2009530302A (ja) | 2009-08-27 |
| CA2645551A1 (en) | 2007-09-27 |
| WO2007109160A2 (en) | 2007-09-27 |
| EP1937643A4 (en) | 2010-03-10 |
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