JP5261398B2 - 目標の生体組織部位に材料又は流体を繰り返し間欠的にデリバリーするための長期にわたって植え込み可能なガイドチューブ - Google Patents
目標の生体組織部位に材料又は流体を繰り返し間欠的にデリバリーするための長期にわたって植え込み可能なガイドチューブ Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/02—Access sites
- A61M39/0208—Subcutaneous access sites for injecting or removing fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/02—Access sites
- A61M39/0247—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M2039/0036—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use characterised by a septum having particular features, e.g. having venting channels or being made from antimicrobial or self-lubricating elastomer
- A61M2039/0081—Means for facilitating introduction of a needle in the septum, e.g. guides, special construction of septum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/02—Access sites
- A61M39/0247—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body
- A61M2039/0285—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body with sterilisation means, e.g. antibacterial coatings, disinfecting pads, UV radiation LEDs or heating means in the port
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/02—Access sites
- A61M39/0247—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body
- A61M2039/0294—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body having a specific shape matching the shape of a tool to be inserted therein, e.g. for easy introduction, for sealing purposes, guide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/32—General characteristics of the apparatus with radio-opaque indicia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0693—Brain, cerebrum
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Materials For Medical Uses (AREA)
Description
(b)第2停止を有する第1のデリバリー・カニューレをガイドチューブの近位端に挿入する、
(c)前記第1停止が前記第2停止に接触するまで前記第1のデリバリー・カニューレを前記ガイドチューブに送り込む、
(d)前記第1のデリバリー・カニューレに第1の薬剤をデリバリーする、そして、
(e)前記第1のデリバリー・カニューレを抜き取る。
(a)ガイドチューブから引き出され、
(b)第3の停止を有する第2のデリバリー・カニューレがガイドチューブの近位端に挿入され、
(c)第1停止が第3の停止に接するまで、第2のデリバリー・カニューレがガイドチューブに送られ、
(d)第1の薬剤と同じである第2の薬剤がデリバリーされ、そして、
(e)第2のデリバリー・カニューレが抜き取られる。
Claims (14)
- 近位端と遠位端を有するガイド・カニューレ、当該ガイド・カニューレの近位端に設けられ、かつ、患者に長期的に植え込むように設けられたアクセス・ポート、及び、前記ガイド・カニューレの遠位端近傍に設けられた第1停止、を備えた長期にわたって植え込み可能なガイドチューブと、
前記第1停止と機械的に相互作用するように設けられた第2停止を有し、前記アクセス・ポートを通って前記ガイド・カニューレに挿入可能なデリバリー・カニューレと、
を有する治療デリバリーシステムであって、
前記第1停止と第2停止の相対的な位置は、前記デリバリー・カニューレの遠位端が前記ガイド・カニューレの遠位端から、予め定められた距離を越えて遠位への伸延を防止し、
前記デリバリー・カニューレの遠位端は、生体組織−穿刺チップを有する治療デリバリーシステム。 - 近位端と遠位端を有するガイド・カニューレ、当該ガイド・カニューレの近位端に設けられ、かつ、患者に長期的に植え込むように設けられたアクセス・ポート、及び、前記ガイド・カニューレの遠位端近傍に設けられた第1停止、を備えた長期にわたって植え込み可能なガイドチューブと、
前記第1停止と機械的に相互作用するように設けられた第2停止を有し、前記アクセス・ポートを通って前記ガイド・カニューレに挿入可能なデリバリー・カニューレと、
少なくとも前記ガイド・カニューレの遠位端領域を閉塞するように設けられた、前記ガイド・カニューレに挿入可能なスタイレットと、
を有する治療デリバリーシステムであって、
前記第1停止と第2停止の相対的な位置は、前記デリバリー・カニューレの遠位端が前記ガイド・カニューレの遠位端から、予め定められた距離を越えて遠位への伸延を防止し、
前記スタイレットは、抗生物質、抗菌性又は殺菌性を有する化学薬品を含む治療デリバリーシステム。 - 前記化学薬品は、抗生物質又は抗炎症からなる薬学的な薬剤を有する請求項2に記載の治療デリバリーシステム。
- 前記化学薬品は、銅ケイ酸塩、銀シリカ、コロイド状の銀、白金黒、トブラマイシン、及び、骨セメントを有する抗菌性又は殺菌性の薬剤、あるいはアルキル化されたポリエチレンイミン又はこのような材料のあらゆる組み合わせを有する請求項2に記載の治療デリバリーシステム。
- 前記スタイレットの遠位端と近位端は、異なる生体組織互換性材料で形成されている請求項2に記載の治療デリバリーシステム。
- 前記スタイレットの遠位端は、生体組織互換性材料で形成され、生体組織互換性材料の近位端は、抗菌性を有する請求項2に記載の治療デリバリーシステム。
- 近位端と遠位端を有するガイド・カニューレ、当該ガイド・カニューレの近位端に設けられ、かつ、患者に長期的に植え込むように設けられたアクセス・ポート、及び、前記ガイド・カニューレの遠位端近傍に設けられた第1停止、を備えた長期にわたって植え込み可能なガイドチューブと、
前記第1停止と機械的に相互作用するように設けられた第2停止を有し、前記アクセス・ポートを通って前記ガイド・カニューレに挿入可能なデリバリー・カニューレと、
を有する治療デリバリーシステムであって、
前記第1停止と第2停止の相対的な位置は、前記デリバリー・カニューレの遠位端が前記ガイド・カニューレの遠位端から、予め定められた距離を越えて遠位への伸延を防止し、
前記ガイド・カニューレは、前記ガイド・カニューレの遠位端に設けられた第1のX線不透過マーカーを有する治療デリバリーシステム。 - さらに複数の前記第1のX線不透過マーカーを有し、前記ガイド・カニューレ経路のX線透視又はX線確認のため、前記ガイド・カニューレの全長に沿って配置されている請求項7に記載の治療デリバリーシステム。
- 近位端と遠位端を有するガイド・カニューレ、当該ガイド・カニューレの近位端に設けられ、かつ、患者に長期的に植え込むように設けられアクセス・ポート、及び、前記ガイド・カニューレの遠位端近傍に設けられた第1停止、を備えた長期にわたって植え込み可能なガイドチューブと、
前記第1停止と機械的に相互作用するように設けられた第2停止を有し、前記アクセス・ポートを通って前記ガイド・カニューレに挿入可能なデリバリー・カニューレと、
を有する治療デリバリーシステムであって、
前記第1停止と第2停止の相対的な位置は、前記デリバリー・カニューレの遠位端が前記ガイド・カニューレの遠位端から、予め定められた距離を越えて遠位への伸延を防止し、
前記デリバリー・カニューレは、前記ガイド・カニューレの遠位端に設けられた第1停止を越える前進を防止するような可撓性材料から形成されている治療デリバリーシステム。 - 前記デリバリー・カニューレは、第2のX線不透過マーカーを有する請求項9に記載の治療デリバリーシステム。
- 前記第2のX線不透過マーカーは、前記デリバリー・カニューレの遠位端に配置されている請求項10に記載の治療デリバリーシステム。
- さらに複数の前記第2のX線不透過マーカーが前記デリバリー・カニューレ経路のX線透視又はX線確認のため、前記デリバリー・カニューレの全長に沿って配置されている請求項10に記載の治療デリバリーシステム。
- 前記第1停止は、フランジを有する請求項1〜12のいずれか1つに記載の治療デリバリーシステム。
- 前記フランジは、前記ガイド・カニューレの遠位端に設けられている請求項13に記載の治療デリバリーシステム。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/562,304 US7819842B2 (en) | 2006-11-21 | 2006-11-21 | Chronically implantable guide tube for repeated intermittent delivery of materials or fluids to targeted tissue sites |
US11/562,304 | 2006-11-21 | ||
PCT/US2007/084803 WO2008064069A2 (en) | 2006-11-21 | 2007-11-15 | A chronically implantable guide tube for repeated intermittent delivery of materials or fluids to targeted tissue sites |
Publications (2)
Publication Number | Publication Date |
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JP2010510030A JP2010510030A (ja) | 2010-04-02 |
JP5261398B2 true JP5261398B2 (ja) | 2013-08-14 |
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JP2009538455A Expired - Fee Related JP5261398B2 (ja) | 2006-11-21 | 2007-11-15 | 目標の生体組織部位に材料又は流体を繰り返し間欠的にデリバリーするための長期にわたって植え込み可能なガイドチューブ |
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Country | Link |
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US (1) | US7819842B2 (ja) |
EP (1) | EP2104530B1 (ja) |
JP (1) | JP5261398B2 (ja) |
CN (1) | CN101652157B (ja) |
WO (1) | WO2008064069A2 (ja) |
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JP2019506250A (ja) * | 2016-02-26 | 2019-03-07 | ニューロナノ アーベー | 細胞凝集体及び組織片の移植の方法 |
JP7006941B2 (ja) | 2016-02-26 | 2022-01-24 | ニューロナノ アーベー | 細胞凝集体及び組織片の移植の方法 |
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WO2008064069A2 (en) | 2008-05-29 |
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CN101652157A (zh) | 2010-02-17 |
EP2104530A2 (en) | 2009-09-30 |
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