JP7006941B2 - 細胞凝集体及び組織片の移植の方法 - Google Patents
細胞凝集体及び組織片の移植の方法 Download PDFInfo
- Publication number
- JP7006941B2 JP7006941B2 JP2018544847A JP2018544847A JP7006941B2 JP 7006941 B2 JP7006941 B2 JP 7006941B2 JP 2018544847 A JP2018544847 A JP 2018544847A JP 2018544847 A JP2018544847 A JP 2018544847A JP 7006941 B2 JP7006941 B2 JP 7006941B2
- Authority
- JP
- Japan
- Prior art keywords
- gel
- pin
- tissue
- channel
- gelatin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 0 *CCC(*)C1CCCC1 Chemical compound *CCC(*)C1CCCC1 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0551—Spinal or peripheral nerve electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/222—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
- A61L27/3675—Nerve tissue, e.g. brain, spinal cord, nerves, dura mater
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/02—Inorganic materials
- A61L31/022—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2576/00—Medical imaging apparatus involving image processing or analysis
- A61B2576/02—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part
- A61B2576/026—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part for the brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4887—Locating particular structures in or on the body
- A61B5/4893—Nerves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/07—Proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/09—Body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3306—Optical measuring means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0693—Brain, cerebrum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/08—Other bio-electrical signals
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H30/00—ICT specially adapted for the handling or processing of medical images
- G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
Description
Claims (14)
- 生細胞の凝集体又は軟組織片を移植するために、水性ゲルで充填された軟組織における直線的なチャネルを形成するための装置であって、
前端及び後端を有する、軸線方向に延在する剛性ピンと、前記前端から遠位方向に延在するピン部分に配置され、前記部分を取り囲む乾燥ゲル形成薬剤を含む又はそれからなる層とを含み又はそれらからなり、
前記層は、20重量%未満の水を含有し、
前記ピンは、それが乾燥ゲル形成薬剤を含む又はそれからなるその層のない状態で神経組織の中に挿入されることを可能にするように充分に剛性であって、
前記ピンは、その前端とその後端との間に延在する通路を含み、
前記通路は、半径方向断面において長方形、菱形、若しくは台形、又は略長方形、略菱形、若しくは略台形である、装置。 - 所与の軸線方向位置における前記通路の半径方向の幅は、それに垂直な前記半径方向の幅より2倍又は3倍又は5倍以上大きい、請求項1に記載の装置。
- 前記ピンの断面は、円筒形、楕円形、長方形、菱形、若しくは台形、又は略円筒形、略楕円形、略長方形、略菱形、若しくは略台形である、請求項1又は2に記載の装置。
- 前記ピンは、金属である、若しくは金属を含む、又はポリマー材料である、請求項1~3の何れか一項に記載の装置。
- 電極手段、光ファイバ手段、センサ手段から選択される1つ以上の手段を含む、請求項1~4の何れか一項に記載の装置。
- 前記軸線方向に延在する通路は、水性体液において溶解可能又は分解可能なプラグによってその遠位開口において塞がれている、請求項1~5の何れか一項に記載の装置。
- 前記プラグは、ゲル形成薬剤からなる又はそれを含む、請求項6に記載の装置。
- 水性体液と接触してゲルを形成することができる前記薬剤が、ゲル形成タンパク質、炭水化物、糖タンパク質からなる群から選択される1つ以上の薬剤を含む、請求項1に記載の装置。
- 水性体液と接触してゲルを形成することができる前記薬剤が、ゼラチン、ヒアルロン酸、化学修飾ゼラチン、組換えゼラチン、化学修飾ヒアルロン酸、組換えヒアルロン酸、及びそれらの塩から選択される、請求項1に記載の装置。
- 前記層は、薬理学的に活性な薬剤を含む、請求項1~9の何れか一項に記載の装置。
- 前記薬理学的に活性な薬剤は、凝固剤、抗凝固剤、抗生物質、浸透圧調節薬剤、抗炎症薬剤、栄養剤、因子刺激成長剤、因子刺激細胞分化剤、ホルモン、免疫抑制薬剤からなる群から選択される、請求項10に記載の装置。
- 水性ゲルで充填された軟組織における直線的なチャネルを形成するためのシステムであって、
請求項1~11の何れか一項に記載の装置と、
前端及び遠位端を有する管状挿入ガイドであって、それを、前記装置の前記ピンが挿入される前記チャネルを形成するための位置に対して固定するための手段を含む管状挿入ガイドと
を含み、乾燥ゲル形成薬剤で覆われた前記装置の前記剛性ピンは、前記挿入ガイドの管腔に配置されている、又は変位可能に摺動に配置されることができる、システム。 - 前記管状挿入ガイドは、その遠位端において取り付けられた半径方向に延在するフランジを含む、請求項12に記載のシステム。
- 前記固定手段は、剛性の保持要素を含み、前記保持要素は、その一端において前記管状挿入ガイド又は前記フランジに取り付けられ、前記保持要素は、その他端において、人又は動物に対する組合せを固定するように、前記組織が属する人又は動物と直接的又は間接的に接続可能である、請求項12又は13に記載のシステム。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE1600070-5 | 2016-02-26 | ||
SE1600070 | 2016-02-26 | ||
PCT/SE2017/000014 WO2017146627A1 (en) | 2016-02-26 | 2017-02-23 | Method of implantation of cell aggregates and tissue fragments |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2019506250A JP2019506250A (ja) | 2019-03-07 |
JP7006941B2 true JP7006941B2 (ja) | 2022-01-24 |
Family
ID=59685420
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2018544847A Active JP7006941B2 (ja) | 2016-02-26 | 2017-02-23 | 細胞凝集体及び組織片の移植の方法 |
Country Status (8)
Country | Link |
---|---|
US (2) | US11724080B2 (ja) |
EP (1) | EP3419715B1 (ja) |
JP (1) | JP7006941B2 (ja) |
CN (1) | CN108778405B (ja) |
AU (3) | AU2017222108B2 (ja) |
CA (1) | CA3014549A1 (ja) |
SG (1) | SG11201806288YA (ja) |
WO (1) | WO2017146627A1 (ja) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP7370981B2 (ja) * | 2018-07-26 | 2023-10-30 | 株式会社カネカ | 生体内留置物の製造方法および留置システム |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006520663A (ja) | 2003-03-20 | 2006-09-14 | ボストン サイエンティフィック リミテッド | 治療用または診断用薬剤送出装置 |
JP2006527009A (ja) | 2002-06-13 | 2006-11-30 | ケンジー ナッシュ コーポレイション | 生体組織における欠損を治療するための装置および方法 |
US20100114069A1 (en) | 2008-10-30 | 2010-05-06 | Warsaw Orthopedic, Inc. | Methods, Systems, and Devices for Treating Intervertebral Discs Including Intradiscal Fluid Evacuation |
JP2012501229A (ja) | 2008-08-29 | 2012-01-19 | スメド−ティーエイ/ティーディー・エルエルシー | 整形外科インプラント |
JP5261398B2 (ja) | 2006-11-21 | 2013-08-14 | メドトロニック,インコーポレイテッド | 目標の生体組織部位に材料又は流体を繰り返し間欠的にデリバリーするための長期にわたって植え込み可能なガイドチューブ |
JP2014528332A (ja) | 2011-10-04 | 2014-10-27 | インキューブ ラブズ, エルエルシー | 固体薬物の送達装置、製剤および使用の方法 |
JP2015523895A (ja) | 2012-06-21 | 2015-08-20 | ニューロナノ アーベー | 医療用電極、電極束及び電極束アレー |
JP2015530904A (ja) | 2012-08-15 | 2015-10-29 | シンセス・ゲーエムベーハーSynthes GmbH | 薬物溶出外科用ねじ |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH677536A5 (ja) * | 1989-03-31 | 1991-05-31 | Ciba Geigy Ag | |
US5610753A (en) | 1991-12-12 | 1997-03-11 | Eastman Kodak Company | Optical design of laser scanner to reduce thermal sensitivity |
US6689608B1 (en) | 1993-02-01 | 2004-02-10 | Massachusetts Institute Of Technology | Porous biodegradable polymeric materials for cell transplantation |
US6171610B1 (en) * | 1998-04-24 | 2001-01-09 | University Of Massachusetts | Guided development and support of hydrogel-cell compositions |
US6613070B2 (en) * | 1998-08-04 | 2003-09-02 | Baxter International Inc. | System and method for sealing vascular penetrations with hemostatic gels |
US6205359B1 (en) * | 1998-10-26 | 2001-03-20 | Birinder Bob Boveja | Apparatus and method for adjunct (add-on) therapy of partial complex epilepsy, generalized epilepsy and involuntary movement disorders utilizing an external stimulator |
CA2282007C (en) * | 1999-09-09 | 2002-05-28 | Ivar Mendez | Neural transplantation delivery system |
TW591106B (en) | 2000-10-06 | 2004-06-11 | Ind Tech Res Inst | Carrier for cell attachment or fixation and its process for preparation |
AU773534B2 (en) * | 2001-08-15 | 2004-05-27 | Nch Corporation | Control agent delivery system and method of use |
US20040136968A1 (en) | 2002-09-27 | 2004-07-15 | Verigen Ag | Autologous cells on a support matrix for tissue repair |
DE10312144B4 (de) * | 2003-03-13 | 2006-12-14 | Technische Universität Dresden | Trägermaterial für die Gewebe- und Zellkultur und die Herstellung von Implantatmaterialien |
US8043614B2 (en) | 2004-03-09 | 2011-10-25 | Ahlfors Jan-Eric W | Autogenic living scaffolds and living tissue matrices: methods and uses thereof |
US7316822B2 (en) * | 2003-11-26 | 2008-01-08 | Ethicon, Inc. | Conformable tissue repair implant capable of injection delivery |
US20060129221A1 (en) * | 2004-12-10 | 2006-06-15 | Medtronic, Inc. | Tunneling guide |
FR2885512B1 (fr) | 2005-05-10 | 2007-08-10 | Biocoral Inc | Seringue pour bio-materiau |
JP4863655B2 (ja) * | 2005-06-17 | 2012-01-25 | 国立大学法人 東京医科歯科大学 | 細胞含有シート |
US8005526B2 (en) | 2005-08-31 | 2011-08-23 | The Regents Of The University Of Michigan | Biologically integrated electrode devices |
US9084546B2 (en) | 2005-08-31 | 2015-07-21 | The Regents Of The University Of Michigan | Co-electrodeposited hydrogel-conducting polymer electrodes for biomedical applications |
US8338402B2 (en) * | 2006-05-12 | 2012-12-25 | Smith & Nephew Plc | Scaffold |
KR20080009911A (ko) * | 2006-07-25 | 2008-01-30 | 경북대학교 산학협력단 | 세포 주입용 주사기 |
US20100041146A1 (en) | 2007-01-12 | 2010-02-18 | Nippon Sheet Glass Company, Limited | Three-dimensional cell culture carrier and method for cell culture using the same |
US9179850B2 (en) | 2007-10-30 | 2015-11-10 | Neuropace, Inc. | Systems, methods and devices for a skull/brain interface |
US20090112278A1 (en) * | 2007-10-30 | 2009-04-30 | Neuropace, Inc. | Systems, Methods and Devices for a Skull/Brain Interface |
CN102209574A (zh) * | 2008-11-10 | 2011-10-05 | Med-El电气医疗器械有限公司 | 植入型和再装填型的药物递送储存器 |
CA2745453C (en) * | 2008-11-10 | 2015-06-16 | Med-El Elektromedizinische Geraete Gmbh | Hydrogel-filled drug delivery reservoirs |
US9351882B2 (en) * | 2008-12-31 | 2016-05-31 | Kci Licensing, Inc. | System for providing fluid flow to nerve tissues |
US20120045487A1 (en) | 2009-04-29 | 2012-02-23 | The Regents Of The University Of Michigan | Multiphasic microfibers for spatially guided cell growth |
JP5850501B2 (ja) * | 2009-06-09 | 2016-02-03 | ニューロナノ アーベー | 微小電極 |
EP2388022A1 (en) | 2010-05-19 | 2011-11-23 | Stichting Dutch Polymer Institute | Cell culture and process for preparing the same |
DE102010052323A1 (de) * | 2010-11-25 | 2012-05-31 | Heraeus Medical Gmbh | Kartusche mit arretierbarem Förderkolben |
US9644177B2 (en) | 2012-07-12 | 2017-05-09 | Board Of Regents, The University Of Texas System | Extracellular matrix films and methods of making and using same |
CA3075578C (en) * | 2013-04-26 | 2022-07-26 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | A multi-component non-biodegradable implant, a method of making and a method of implantation |
IL246157B (en) * | 2013-12-20 | 2022-08-01 | Neuronano Ab | A medical device consisting of an electrode and a light source |
CN103767804A (zh) * | 2014-01-20 | 2014-05-07 | 清华大学 | 一种具有微流体通道的血管化组织结构及其制备方法 |
JP6621216B2 (ja) * | 2014-08-27 | 2019-12-18 | ニューロナノ アーベー | 神経組織への医療機器の植込み方法 |
-
2017
- 2017-02-23 WO PCT/SE2017/000014 patent/WO2017146627A1/en active Application Filing
- 2017-02-23 CA CA3014549A patent/CA3014549A1/en active Pending
- 2017-02-23 EP EP17756917.5A patent/EP3419715B1/en active Active
- 2017-02-23 AU AU2017222108A patent/AU2017222108B2/en active Active
- 2017-02-23 CN CN201780013517.6A patent/CN108778405B/zh active Active
- 2017-02-23 US US16/073,373 patent/US11724080B2/en active Active
- 2017-02-23 JP JP2018544847A patent/JP7006941B2/ja active Active
- 2017-02-23 SG SG11201806288YA patent/SG11201806288YA/en unknown
-
2019
- 2019-06-14 AU AU2019204187A patent/AU2019204187B2/en active Active
-
2020
- 2020-04-30 AU AU2020202868A patent/AU2020202868B2/en active Active
-
2023
- 2023-06-28 US US18/215,210 patent/US20230338722A1/en active Pending
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006527009A (ja) | 2002-06-13 | 2006-11-30 | ケンジー ナッシュ コーポレイション | 生体組織における欠損を治療するための装置および方法 |
JP2006520663A (ja) | 2003-03-20 | 2006-09-14 | ボストン サイエンティフィック リミテッド | 治療用または診断用薬剤送出装置 |
JP5261398B2 (ja) | 2006-11-21 | 2013-08-14 | メドトロニック,インコーポレイテッド | 目標の生体組織部位に材料又は流体を繰り返し間欠的にデリバリーするための長期にわたって植え込み可能なガイドチューブ |
JP2012501229A (ja) | 2008-08-29 | 2012-01-19 | スメド−ティーエイ/ティーディー・エルエルシー | 整形外科インプラント |
US20100114069A1 (en) | 2008-10-30 | 2010-05-06 | Warsaw Orthopedic, Inc. | Methods, Systems, and Devices for Treating Intervertebral Discs Including Intradiscal Fluid Evacuation |
JP2014528332A (ja) | 2011-10-04 | 2014-10-27 | インキューブ ラブズ, エルエルシー | 固体薬物の送達装置、製剤および使用の方法 |
JP2015523895A (ja) | 2012-06-21 | 2015-08-20 | ニューロナノ アーベー | 医療用電極、電極束及び電極束アレー |
JP2015530904A (ja) | 2012-08-15 | 2015-10-29 | シンセス・ゲーエムベーハーSynthes GmbH | 薬物溶出外科用ねじ |
Also Published As
Publication number | Publication date |
---|---|
EP3419715A4 (en) | 2020-05-06 |
US20230338722A1 (en) | 2023-10-26 |
CA3014549A1 (en) | 2017-08-31 |
AU2020202868B2 (en) | 2022-08-04 |
JP2019506250A (ja) | 2019-03-07 |
SG11201806288YA (en) | 2018-08-30 |
WO2017146627A1 (en) | 2017-08-31 |
CN108778405A (zh) | 2018-11-09 |
AU2019204187A1 (en) | 2019-07-04 |
AU2017222108B2 (en) | 2019-04-04 |
EP3419715A1 (en) | 2019-01-02 |
CN108778405B (zh) | 2023-06-13 |
AU2020202868A1 (en) | 2020-07-30 |
US11724080B2 (en) | 2023-08-15 |
AU2017222108A1 (en) | 2018-08-09 |
AU2019204187B2 (en) | 2020-01-30 |
US20190030310A1 (en) | 2019-01-31 |
EP3419715B1 (en) | 2021-09-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR102560511B1 (ko) | 의료 기구의 신경 조직내 이식 방법 | |
Scheper et al. | Stem cell based drug delivery for protection of auditory neurons in a guinea pig model of cochlear implantation | |
US20230405181A1 (en) | Method of providing an implantation site in soft tissue | |
US20230338722A1 (en) | Method of implantation of cell aggregates and tissue fragments | |
Hügl et al. | Coating stability and insertion forces of an alginate-cell-based drug delivery implant system for the inner ear | |
TWI630934B (zh) | 移植醫藥設備到神經組織中的方法以及設備 | |
Hajosch et al. | A novel microsurgical nerve implantation technique preserving outer nerve layers | |
Hügl et al. | Journal of the Mechanical Behavior of Biomedical Materials | |
Lewitus | Biomaterial strategies towards the development of next generation neural prosthetic devices |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20181026 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20191126 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20201105 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20201112 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20210203 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20210330 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20210512 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20210707 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20211007 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20211130 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20211224 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 7006941 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |