JP5174659B2 - リウマチ疾患の診断方法 - Google Patents
リウマチ疾患の診断方法 Download PDFInfo
- Publication number
- JP5174659B2 JP5174659B2 JP2008518703A JP2008518703A JP5174659B2 JP 5174659 B2 JP5174659 B2 JP 5174659B2 JP 2008518703 A JP2008518703 A JP 2008518703A JP 2008518703 A JP2008518703 A JP 2008518703A JP 5174659 B2 JP5174659 B2 JP 5174659B2
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- vimentin
- detection
- rheumatoid arthritis
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Rehabilitation Therapy (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005029845.1 | 2005-06-27 | ||
| DE102005029845.1A DE102005029845B4 (de) | 2005-06-27 | 2005-06-27 | Verfahren zur Diagnose von rheumatischen Erkrankungen |
| PCT/EP2006/006205 WO2007000320A2 (de) | 2005-06-27 | 2006-06-27 | Verfahren zur diagnose von rheumatischen erkrankungen |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012193246A Division JP2013032358A (ja) | 2005-06-27 | 2012-09-03 | リウマチ疾患の診断方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008543961A JP2008543961A (ja) | 2008-12-04 |
| JP2008543961A5 JP2008543961A5 (https=) | 2009-07-23 |
| JP5174659B2 true JP5174659B2 (ja) | 2013-04-03 |
Family
ID=37309237
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008518703A Active JP5174659B2 (ja) | 2005-06-27 | 2006-06-27 | リウマチ疾患の診断方法 |
| JP2012193246A Pending JP2013032358A (ja) | 2005-06-27 | 2012-09-03 | リウマチ疾患の診断方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012193246A Pending JP2013032358A (ja) | 2005-06-27 | 2012-09-03 | リウマチ疾患の診断方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8999921B2 (https=) |
| EP (1) | EP1896497B1 (https=) |
| JP (2) | JP5174659B2 (https=) |
| CN (1) | CN101282989A (https=) |
| AU (1) | AU2006263942B9 (https=) |
| CA (1) | CA2614103C (https=) |
| DE (2) | DE102005029845B4 (https=) |
| WO (1) | WO2007000320A2 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005029845B4 (de) | 2005-06-27 | 2017-03-23 | Orgentec Diagnostika Gmbh | Verfahren zur Diagnose von rheumatischen Erkrankungen |
| CA2690568A1 (en) * | 2007-06-20 | 2008-12-24 | Schering Corporation | Joint destruction biomarkers for anti-il-17a therapy of inflammatory joint disease |
| EP2204380A1 (en) | 2008-12-23 | 2010-07-07 | Charité-Universitätsmedizin Berlin | hnRNP A3 related peptides and use thereof for diagnosis of rheumatoid arthritis |
| NZ608489A (en) | 2009-03-30 | 2014-08-29 | Nestec Sa | Citrullinated peptides for diagnosing and prognosing rheumatiod arthritis |
| CN102229652B (zh) * | 2009-10-23 | 2012-05-23 | 山东省医药生物技术研究中心 | 抗类风湿性关节炎的多肽及其在制药中的应用 |
| US10011883B2 (en) | 2011-10-14 | 2018-07-03 | New York University | Causative agents and diagnostic methods relating to rheumatoid arthritis |
| WO2013151314A1 (ko) * | 2012-04-03 | 2013-10-10 | 연세대학교 산학협력단 | 비멘틴을 포함하는 탈모 억제 또는 발모 촉진용 조성물 |
| GB201214007D0 (en) | 2012-08-07 | 2012-09-19 | Scancell Ltd | Anti-tumour immune responses to modified self-epitopes |
| WO2016199964A1 (ko) * | 2015-06-10 | 2016-12-15 | 주식회사 이뮨메드 | 분리된 비멘틴 유래 펩타이드에 특이적으로 결합하는 항체 또는 상기 펩타이드의 결합 단편 |
| GB201512703D0 (en) | 2015-07-20 | 2015-08-26 | Scancell Ltd | Anti-tumour immune responses to modified self-epitopes |
| CN106950365B (zh) * | 2017-02-15 | 2018-11-27 | 中国医学科学院北京协和医院 | 一种acpa阴性的ra诊断标志物及其应用 |
| GB201815041D0 (en) | 2018-09-14 | 2018-10-31 | Scancell Ltd | Epitopes |
| WO2022108309A1 (ko) * | 2020-11-18 | 2022-05-27 | 한양대학교 에리카산학협력단 | 인산화된 비멘틴의 과도한 생성을 차단하여 암을 예방 또는 치료하는 방법 |
| KR102511660B1 (ko) * | 2020-11-18 | 2023-03-20 | 한양대학교 에리카산학협력단 | 비멘틴 돌연변이체 또는 이를 발현하는 벡터를 유효성분으로 포함하는 암 예방 또는 치료용 약학적 조성물 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9900473D0 (sv) * | 1999-02-12 | 1999-02-12 | Karolinska Innovations Ab | Inhibitor of endothelial cell proliferation |
| EP1207862A2 (en) * | 1999-06-07 | 2002-05-29 | The University Of Sheffield | Arthritis treatment |
| CA2518187A1 (en) * | 2003-03-07 | 2004-09-16 | London Health Sciences Centre Reseach, Inc. | Peptides associated with hla-dr mhc class ii molecules involved in autoimmune diseases |
| DE102005029845B4 (de) | 2005-06-27 | 2017-03-23 | Orgentec Diagnostika Gmbh | Verfahren zur Diagnose von rheumatischen Erkrankungen |
-
2005
- 2005-06-27 DE DE102005029845.1A patent/DE102005029845B4/de not_active Expired - Fee Related
-
2006
- 2006-06-27 EP EP06762214.2A patent/EP1896497B1/de active Active
- 2006-06-27 JP JP2008518703A patent/JP5174659B2/ja active Active
- 2006-06-27 CN CNA2006800312026A patent/CN101282989A/zh active Pending
- 2006-06-27 DE DE202006020682U patent/DE202006020682U1/de not_active Expired - Lifetime
- 2006-06-27 AU AU2006263942A patent/AU2006263942B9/en not_active Ceased
- 2006-06-27 US US11/597,515 patent/US8999921B2/en active Active
- 2006-06-27 WO PCT/EP2006/006205 patent/WO2007000320A2/de not_active Ceased
- 2006-06-27 CA CA2614103A patent/CA2614103C/en not_active Expired - Fee Related
-
2012
- 2012-09-03 JP JP2012193246A patent/JP2013032358A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1896497A2 (de) | 2008-03-12 |
| DE102005029845A1 (de) | 2007-01-11 |
| CA2614103C (en) | 2015-02-24 |
| DE202006020682U1 (de) | 2009-07-23 |
| AU2006263942B2 (en) | 2012-03-29 |
| US20090155822A1 (en) | 2009-06-18 |
| WO2007000320A2 (de) | 2007-01-04 |
| CA2614103A1 (en) | 2007-01-04 |
| CN101282989A (zh) | 2008-10-08 |
| JP2013032358A (ja) | 2013-02-14 |
| DE102005029845B4 (de) | 2017-03-23 |
| AU2006263942B9 (en) | 2012-08-02 |
| JP2008543961A (ja) | 2008-12-04 |
| WO2007000320A3 (de) | 2007-07-05 |
| EP1896497B1 (de) | 2017-07-12 |
| US8999921B2 (en) | 2015-04-07 |
| AU2006263942A1 (en) | 2007-01-04 |
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