JP5095894B2 - リポタンパク質リパーゼ（ｌｐｌ）変異体治療薬 - Google Patents
リポタンパク質リパーゼ（ｌｐｌ）変異体治療薬 Download PDFInfo
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/898,684 US20110201673A1 (en) | 1999-06-24 | 2010-10-05 | Lpl variant therapeutics |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99202048 | 1999-06-24 | ||
| EP99202048.7 | 1999-06-24 | ||
| PCT/CA2000/000762 WO2001000220A2 (en) | 1999-06-24 | 2000-06-23 | Lipoprotein lipase (lpl) variant therapeutics |
Publications (3)
| Publication Number | Publication Date |
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| JP2003503355A JP2003503355A (ja) | 2003-01-28 |
| JP2003503355A5 JP2003503355A5 (https=) | 2007-08-09 |
| JP5095894B2 true JP5095894B2 (ja) | 2012-12-12 |
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Family Applications (1)
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| US (1) | US20110201673A1 (https=) |
| EP (1) | EP1200117B1 (https=) |
| JP (1) | JP5095894B2 (https=) |
| AT (1) | ATE404217T1 (https=) |
| AU (1) | AU5799200A (https=) |
| CA (1) | CA2370081C (https=) |
| CY (1) | CY1108511T1 (https=) |
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| ES (1) | ES2311464T3 (https=) |
| PT (1) | PT1200117E (https=) |
| WO (1) | WO2001000220A2 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20070015518A (ko) * | 2004-03-02 | 2007-02-05 | 셀렉타, 엘엘씨 | 암의 진단 및 치료를 위한 포스포리피드 유사체 |
| SI1761273T1 (sl) * | 2004-06-21 | 2008-10-31 | Amsterdam Molecular Therapeutics Bv | Zdravljenje nealkoholnega steatoznega hepatitisa |
| EP2311967B1 (en) | 2005-10-20 | 2017-09-20 | UniQure IP B.V. | Improved AAV vectors produced in insect cells |
| KR101589259B1 (ko) | 2006-06-21 | 2016-02-01 | 유니큐어 아이피 비.브이. | 곤충세포 내 ａａｖ의 생산에 유용한 ａａｖ-ｒｅｐ78의 번역을 위한 변형된 개시 코돈을 갖는 벡터 |
| SI3093345T1 (sl) | 2007-07-26 | 2019-08-30 | Uniqure Ip B.V. | Bakulovirusni vektorji, ki vsebujejo ponavljajoča kodirna zaporedja z različnimi kodonskimi preferencami |
| WO2009030254A1 (en) * | 2007-09-04 | 2009-03-12 | Curevac Gmbh | Complexes of rna and cationic peptides for transfection and for immunostimulation |
| EP2432497A1 (en) * | 2009-05-18 | 2012-03-28 | Amsterdam Molecular Therapeutics (AMT) IP B.V. | Use of lipoprotein lipase (lpl) in therapy |
| SI3708192T1 (sl) | 2009-06-12 | 2023-12-29 | Cellectar, Inc. | Eter fosfolipidne spojine za zdravljenje raka in slikanje in detekcijo rakavih izvornih celic |
| WO2011112089A2 (en) | 2010-03-11 | 2011-09-15 | Amsterdam Molecular Therapeutics (Amt) Ip B.V. | Mutated rep encoding sequences for use in aav production |
| WO2011122950A1 (en) | 2010-04-01 | 2011-10-06 | Amsterdam Molecular Therapeutics (Amt) Ip B.V. | Monomeric duplex aav vectors |
| CA2863964C (en) | 2012-02-07 | 2021-10-26 | Global Bio Therapeutics Usa, Inc. | Compartmentalized method of nucleic acid delivery and compositions and uses thereof |
| US10023626B2 (en) | 2013-09-30 | 2018-07-17 | Modernatx, Inc. | Polynucleotides encoding immune modulating polypeptides |
| JP2016538829A (ja) | 2013-10-03 | 2016-12-15 | モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | 低密度リポタンパク質受容体をコードするポリヌクレオチド |
| WO2015137802A1 (en) | 2014-03-10 | 2015-09-17 | Uniqure Ip B.V. | Further improved aav vectors produced in insect cells |
| MA41035A (fr) | 2014-08-19 | 2017-08-15 | Shire Human Genetic Therapies | Lipoprotéine lipase pour le traitement d'affections liées à une hypertriglycéridémie, y compris la pancréatite aiguë |
| EP3458106A4 (en) | 2016-05-18 | 2020-03-18 | Modernatx, Inc. | POLYNUCLEOTIDS FOR CODING LIPOPROTEIN LIPASE FOR TREATING HYPERLIPIDEMIA |
| WO2018109207A1 (en) | 2016-12-16 | 2018-06-21 | Uniqure Ip B.V. | Immunoadsorption |
| PT3652326T (pt) | 2017-07-10 | 2024-12-26 | Uniqure Ip Bv | Meios e métodos para terapia génica de aav em humanos |
| JP7666922B2 (ja) | 2017-07-20 | 2025-04-22 | ユニキュアー アイピー ビー．ブイ． | 昆虫細胞における向上したａａｖカプシド産生 |
| CA3084452A1 (en) | 2017-12-29 | 2019-07-04 | Uniqure Ip B.V. | Modified viral vectors and methods of making and using the same |
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| EP0755268A1 (en) * | 1994-04-11 | 1997-01-29 | Baylor College Of Medicine | Compositions and methods for gene therapy to treat disease |
| US5658729A (en) * | 1994-10-11 | 1997-08-19 | The University Of British Columbia | Method, reagent and kit for evaluating susceptibility to premature atherosclerosis |
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2000
- 2000-06-23 AT AT00943499T patent/ATE404217T1/de active
- 2000-06-23 JP JP2001505929A patent/JP5095894B2/ja not_active Expired - Fee Related
- 2000-06-23 DK DK00943499T patent/DK1200117T3/da active
- 2000-06-23 PT PT00943499T patent/PT1200117E/pt unknown
- 2000-06-23 DE DE60039880T patent/DE60039880D1/de not_active Expired - Lifetime
- 2000-06-23 WO PCT/CA2000/000762 patent/WO2001000220A2/en not_active Ceased
- 2000-06-23 AU AU57992/00A patent/AU5799200A/en not_active Abandoned
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- 2000-06-23 ES ES00943499T patent/ES2311464T3/es not_active Expired - Lifetime
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- 2008-11-13 CY CY20081101305T patent/CY1108511T1/el unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| EP1200117B1 (en) | 2008-08-13 |
| CA2370081A1 (en) | 2001-01-04 |
| WO2001000220A3 (en) | 2001-07-12 |
| WO2001000220A2 (en) | 2001-01-04 |
| DK1200117T3 (da) | 2008-11-17 |
| ES2311464T3 (es) | 2009-02-16 |
| PT1200117E (pt) | 2008-11-26 |
| CY1108511T1 (el) | 2014-04-09 |
| DE60039880D1 (en) | 2008-09-25 |
| JP2003503355A (ja) | 2003-01-28 |
| ATE404217T1 (de) | 2008-08-15 |
| US20110201673A1 (en) | 2011-08-18 |
| CA2370081C (en) | 2014-06-03 |
| AU5799200A (en) | 2001-01-31 |
| EP1200117A2 (en) | 2002-05-02 |
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