JP5090928B2 - Ｎｋｔ細胞に対する抗原としての糖脂質及びその類似体 - Google Patents

Ｎｋｔ細胞に対する抗原としての糖脂質及びその類似体 Download PDF

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JP5090928B2
JP5090928B2 JP2007548576A JP2007548576A JP5090928B2 JP 5090928 B2 JP5090928 B2 JP 5090928B2 JP 2007548576 A JP2007548576 A JP 2007548576A JP 2007548576 A JP2007548576 A JP 2007548576A JP 5090928 B2 JP5090928 B2 JP 5090928B2
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cells
formula
compound
nkt
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JP2008525495A5 (enExample
JP2008525495A (ja
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チ−フイ ウォン
ダグ ウー
マサカズ フジオ
モリヤ ツジ
デーヴィッド ホー
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Rockefeller University
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/06—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical being a hydroxyalkyl group esterified by a fatty acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
JP2007548576A 2004-12-28 2005-12-27 Ｎｋｔ細胞に対する抗原としての糖脂質及びその類似体 Expired - Fee Related JP5090928B2 (ja)

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Application Number Priority Date Filing Date Title
US63940804P 2004-12-28 2004-12-28
US60/639,408 2004-12-28
PCT/US2005/047017 WO2006071848A2 (en) 2004-12-28 2005-12-27 Glycolipids and analogues thereof as antigens for nk t cells

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JP2008525495A JP2008525495A (ja) 2008-07-17
JP2008525495A5 JP2008525495A5 (enExample) 2009-02-19
JP5090928B2 true JP5090928B2 (ja) 2012-12-05

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JP2007548576A Expired - Fee Related JP5090928B2 (ja) 2004-12-28 2005-12-27 Ｎｋｔ細胞に対する抗原としての糖脂質及びその類似体

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US (2) US7534434B2 (enExample)
EP (1) EP1833489A4 (enExample)
JP (1) JP5090928B2 (enExample)
AU (1) AU2005322027B2 (enExample)
CA (1) CA2591232C (enExample)
WO (1) WO2006071848A2 (enExample)

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US10338069B2 (en) 2010-04-12 2019-07-02 Academia Sinica Glycan arrays for high throughput screening of viruses
ES2654382T3 (es) 2011-01-05 2018-02-13 National Taiwan University Método para la preparación de glucoesfingolípidos
US20120288525A1 (en) 2011-05-11 2012-11-15 Chakravarty Sumana Pharmaceutical compositions comprising attenuated plasmodium sporozoites and glycolipid adjuvants
US10130714B2 (en) 2012-04-14 2018-11-20 Academia Sinica Enhanced anti-influenza agents conjugated with anti-inflammatory activity
CN104736550B (zh) * 2012-07-26 2017-12-29 维多利亚联结有限公司 有机化合物
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TW201620939A (zh) 2014-01-16 2016-06-16 中央研究院 治療及檢測癌症之組合物及方法
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WO2006071848A3 (en) 2006-09-14
CA2591232A1 (en) 2006-07-06
WO2006071848A9 (en) 2006-08-17
AU2005322027A1 (en) 2006-07-06
US20090233875A1 (en) 2009-09-17
WO2006071848A2 (en) 2006-07-06
EP1833489A4 (en) 2011-08-03
EP1833489A2 (en) 2007-09-19
AU2005322027B2 (en) 2013-09-12
US7534434B2 (en) 2009-05-19
CA2591232C (en) 2014-10-21
JP2008525495A (ja) 2008-07-17
US20060211856A1 (en) 2006-09-21

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