JP5086988B2 - 乾粉エアロゾル化吸入器 - Google Patents

乾粉エアロゾル化吸入器 Download PDF

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Publication number
JP5086988B2
JP5086988B2 JP2008503352A JP2008503352A JP5086988B2 JP 5086988 B2 JP5086988 B2 JP 5086988B2 JP 2008503352 A JP2008503352 A JP 2008503352A JP 2008503352 A JP2008503352 A JP 2008503352A JP 5086988 B2 JP5086988 B2 JP 5086988B2
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JP
Japan
Prior art keywords
inner diameter
main body
drug
drug loading
mouthpiece
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Expired - Fee Related
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JP2008503352A
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English (en)
Japanese (ja)
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JP2008534091A (ja
JP2008534091A5 (Direct
Inventor
チェン，チンタン
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Individual
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Application filed by Individual filed Critical Individual
Publication of JP2008534091A publication Critical patent/JP2008534091A/ja
Publication of JP2008534091A5 publication Critical patent/JP2008534091A5/ja
Application granted granted Critical
Publication of JP5086988B2 publication Critical patent/JP5086988B2/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0013—Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0015—Details of inhalators; Constructional features thereof with inhalation check valves located upstream of the dispenser, i.e. not traversed by the product
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/14—Static flow deviators in tubes disturbing laminar flow in tubes, e.g. archimedes screws

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
JP2008503352A 2005-04-04 2006-03-13 乾粉エアロゾル化吸入器 Expired - Fee Related JP5086988B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN200510038681.1 2005-04-04
CNB2005100386811A CN100431634C (zh) 2005-04-04 2005-04-04 干粉气溶胶化吸入器
PCT/CN2006/000381 WO2006105709A1 (en) 2005-04-04 2006-03-13 Dry powder aerosolizing inhaler

Publications (3)

Publication Number Publication Date
JP2008534091A JP2008534091A (ja) 2008-08-28
JP2008534091A5 JP2008534091A5 (Direct) 2009-05-07
JP5086988B2 true JP5086988B2 (ja) 2012-11-28

Family

ID=35038170

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008503352A Expired - Fee Related JP5086988B2 (ja) 2005-04-04 2006-03-13 乾粉エアロゾル化吸入器

Country Status (6)

Country Link
US (1) US8978645B2 (Direct)
EP (1) EP1872817B1 (Direct)
JP (1) JP5086988B2 (Direct)
CN (1) CN100431634C (Direct)
AT (1) ATE539785T1 (Direct)
WO (1) WO2006105709A1 (Direct)

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US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
SI1494732T1 (sl) 2002-03-20 2008-08-31 Mannking Corp Inhalacijski aparat
AU2005277208B2 (en) 2004-08-20 2011-11-24 Mannkind Corporation Catalysis of diketopiperazine synthesis
DK1791542T3 (en) 2004-08-23 2015-06-15 Mannkind Corp Diketopiperazinsalte for pharmaceutical delivery
KR101486397B1 (ko) 2005-09-14 2015-01-28 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
AU2007216966C1 (en) 2006-02-22 2014-03-20 Mannkind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
EP2534958A1 (en) 2007-12-14 2012-12-19 AeroDesigns, Inc Delivering aerosolizable food products
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
CN109568740B (zh) 2008-06-13 2022-05-27 曼金德公司 干粉吸入器和用于药物输送的系统
BRPI0914308B8 (pt) * 2008-06-20 2021-06-22 Mannkind Corp sistema de inalação
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2405963B1 (en) 2009-03-11 2013-11-06 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
MY186975A (en) 2009-06-12 2021-08-26 Mannkind Corp Diketopiperazine microparticles with defined specific surface areas
WO2011013003A2 (en) 2009-07-31 2011-02-03 Shin Nippon Biomedical Laboratories, Ltd. Intranasal granisetron and nasal applicator
EP2496295A1 (en) 2009-11-03 2012-09-12 MannKind Corporation An apparatus and method for simulating inhalation efforts
IL223742A (en) 2010-06-21 2016-06-30 Mannkind Corp A dry powder inhaler and preparation for it
CN102553040B (zh) * 2010-12-17 2014-07-02 陈庆堂 滤出药粉吸入器
CA2825541C (en) 2011-01-31 2020-06-02 Tatsuo Tsutsui Intranasal delivery devices
DK2694402T3 (en) 2011-04-01 2017-07-03 Mannkind Corp BLISTER PACKAGE FOR PHARMACEUTICAL CYLINDER AMPULS
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
HK1201475A1 (en) 2011-10-24 2015-09-04 Mannkind Corporation Methods and compositions for treating pain
SG11201500218VA (en) 2012-07-12 2015-03-30 Mannkind Corp Dry powder drug delivery systems and methods
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
ES2754388T3 (es) 2013-03-15 2020-04-17 Mannkind Corp Composiciones y métodos de dicetopiperazina microcristalina
EP3021834A1 (en) 2013-07-18 2016-05-25 MannKind Corporation Heat-stable dry powder pharmaceutical compositions and methods
JP2016530930A (ja) 2013-08-05 2016-10-06 マンカインド コーポレイション 通気装置及び方法
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
CN106075677B (zh) * 2016-08-08 2022-06-10 中山市美捷时包装制品有限公司 一种干粉吸入装置的促动机构
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
CN109821118B (zh) * 2017-11-23 2025-12-23 正大天晴药业集团股份有限公司 新型肺部药物输送系统
US11925751B2 (en) * 2018-03-26 2024-03-12 Philip Morris Products S.A. Inhaler with aperatured porous support element
CN115702961A (zh) * 2021-08-03 2023-02-17 上海臣邦医药科技股份有限公司 一种单剂量可抛弃型粉雾剂装置

Family Cites Families (26)

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FI69963C (fi) * 1984-10-04 1986-09-12 Orion Yhtymae Oy Doseringsanordning
US5201308A (en) * 1990-02-14 1993-04-13 Newhouse Michael T Powder inhaler
GB9015522D0 (en) * 1990-07-13 1990-08-29 Braithwaite Philip W Inhaler
DE4211475A1 (de) 1991-12-14 1993-06-17 Asta Medica Ag Pulverinhalator
US5239993A (en) * 1992-08-26 1993-08-31 Glaxo Inc. Dosage inhalator providing optimized compound inhalation trajectory
US5349947A (en) * 1993-07-15 1994-09-27 Newhouse Michael T Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow
WO1995024183A1 (en) * 1994-03-07 1995-09-14 Inhale Therapeutic Systems Methods and compositions for pulmonary delivery of insulin
FR2718968B1 (fr) * 1994-04-20 1996-07-26 Valois Sa Insert délimitant une chambre de dosage d'un inhalateur.
JP3669710B2 (ja) * 1995-12-07 2005-07-13 ヤゴ リサーチ アクチェンゲゼルシャフト 薬理学的乾燥粉末を多数回投薬するための吸入器と吸い口
JP3328131B2 (ja) * 1996-03-15 2002-09-24 株式会社ユニシアジェックス 吸入式投薬器
GB9626263D0 (en) * 1996-12-18 1997-02-05 Innovata Biomed Ltd Powder inhaler
JP3530004B2 (ja) 1998-02-06 2004-05-24 株式会社日立ユニシアオートモティブ 吸入式投薬器
US6234169B1 (en) * 1998-08-14 2001-05-22 Arthur Slutsky Inhaler
JP2000217917A (ja) * 1999-01-27 2000-08-08 Unisia Jecs Corp 吸入式投薬器
JP2000217919A (ja) * 1999-01-28 2000-08-08 Unisia Jecs Corp 吸入式投薬器
GB2353222B (en) * 1999-06-23 2001-09-19 Cambridge Consultants Inhalers
US7464706B2 (en) * 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
CN2391625Y (zh) 1999-11-07 2000-08-16 范崇盛 新型多用途雾化吸入器
GB0015043D0 (en) 2000-06-21 2000-08-09 Glaxo Group Ltd Medicament dispenser
PE20020066A1 (es) * 2000-06-23 2002-02-23 Norton Healthcare Ltd Deposito de dosis medidas previamente para inhalador de polvo seco accionado por la respiracion
DE10040528A1 (de) * 2000-08-18 2002-02-28 Pari Gmbh Inhalationsvorrichtung und Verfahren zur Erzeugung eines Partikelnebels für Inhalationszwecke
EP1658872B2 (en) * 2002-07-31 2019-08-21 CHIESI FARMACEUTICI S.p.A. Powder inhaler
DE10244795A1 (de) * 2002-09-26 2004-04-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator
JP3590848B1 (ja) * 2003-05-09 2004-11-17 大塚製薬株式会社 粉末吸入器
JP3616877B2 (ja) * 2002-10-11 2005-02-02 大塚製薬株式会社 粉末吸入器
CN2794531Y (zh) * 2005-04-04 2006-07-12 陈庆堂 干粉气溶胶化吸入器

Also Published As

Publication number Publication date
US20090025720A1 (en) 2009-01-29
EP1872817A1 (en) 2008-01-02
CN100431634C (zh) 2008-11-12
WO2006105709A1 (en) 2006-10-12
ATE539785T1 (de) 2012-01-15
CN1666788A (zh) 2005-09-14
JP2008534091A (ja) 2008-08-28
EP1872817A4 (en) 2010-07-14
EP1872817B1 (en) 2012-01-04
US8978645B2 (en) 2015-03-17

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