JP5078350B2 - 縮合ヘテロ環誘導体、それを含有する医薬組成物およびその医薬用途 - Google Patents
縮合ヘテロ環誘導体、それを含有する医薬組成物およびその医薬用途 Download PDFInfo
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- JP5078350B2 JP5078350B2 JP2006510804A JP2006510804A JP5078350B2 JP 5078350 B2 JP5078350 B2 JP 5078350B2 JP 2006510804 A JP2006510804 A JP 2006510804A JP 2006510804 A JP2006510804 A JP 2006510804A JP 5078350 B2 JP5078350 B2 JP 5078350B2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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Landscapes
- Health & Medical Sciences (AREA)
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- Hematology (AREA)
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- Cardiology (AREA)
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- Biotechnology (AREA)
- Biochemistry (AREA)
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- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006510804A JP5078350B2 (ja) | 2004-03-04 | 2005-03-03 | 縮合ヘテロ環誘導体、それを含有する医薬組成物およびその医薬用途 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004061429 | 2004-03-04 | ||
| JP2004061429 | 2004-03-04 | ||
| JP2006510804A JP5078350B2 (ja) | 2004-03-04 | 2005-03-03 | 縮合ヘテロ環誘導体、それを含有する医薬組成物およびその医薬用途 |
| PCT/JP2005/004152 WO2005085265A1 (ja) | 2004-03-04 | 2005-03-03 | 縮合ヘテロ環誘導体、それを含有する医薬組成物およびその医薬用途 |
Publications (2)
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| JPWO2005085265A1 JPWO2005085265A1 (ja) | 2008-01-17 |
| JP5078350B2 true JP5078350B2 (ja) | 2012-11-21 |
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| JP2006510804A Expired - Fee Related JP5078350B2 (ja) | 2004-03-04 | 2005-03-03 | 縮合ヘテロ環誘導体、それを含有する医薬組成物およびその医薬用途 |
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| Country | Link |
|---|---|
| US (1) | US7732596B2 (enExample) |
| EP (1) | EP1724277A4 (enExample) |
| JP (1) | JP5078350B2 (enExample) |
| KR (1) | KR101214433B1 (enExample) |
| CN (1) | CN1934122B (enExample) |
| AU (1) | AU2005219777B2 (enExample) |
| CA (1) | CA2557320C (enExample) |
| IL (1) | IL177513A (enExample) |
| MA (1) | MA28512B1 (enExample) |
| NO (1) | NO20064412L (enExample) |
| NZ (1) | NZ549219A (enExample) |
| PL (1) | PL381247A1 (enExample) |
| RU (1) | RU2387663C2 (enExample) |
| TW (1) | TW200540167A (enExample) |
| WO (1) | WO2005085265A1 (enExample) |
| ZA (1) | ZA200606792B (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2387881T3 (es) | 2004-03-16 | 2012-10-03 | Boehringer Ingelheim International Gmbh | Derivados de benceno sustituidos por glucopiranosilo, medicamentos que contienen estos compuestos, su uso y procedimiento para su preparación |
| CA2587639A1 (en) | 2004-12-16 | 2006-06-22 | Boehringer Ingelheim International Gmbh | Glucopyranosyl-substituted benzene derivatives, medicaments containing such compounds, their use and process for their manufacture |
| TW200637869A (en) | 2005-01-28 | 2006-11-01 | Chugai Pharmaceutical Co Ltd | The spiroketal derivatives and the use as therapeutical agent for diabetes of the same |
| DE602006009772D1 (de) | 2005-02-23 | 2009-11-26 | Boehringer Ingelheim Int | Glucopyranosylsubstituierte ((hetero)arylethynyl-benzyl)-benzenderivative und deren verwendung als inhibitoren des natriumabhängigen glucose-cotransporters typ 2 (sglt2) |
| ATE453656T1 (de) | 2005-04-15 | 2010-01-15 | Boehringer Ingelheim Int | Glucopyranosyl-substituierte (heteroaryloxy- benzyl)-benzen-derivate als sglt-inhibitoren |
| UA91546C2 (uk) | 2005-05-03 | 2010-08-10 | Бьорінгер Інгельхайм Інтернаціональ Гмбх | КРИСТАЛІЧНА ФОРМА 1-ХЛОР-4-(β-D-ГЛЮКОПІРАНОЗ-1-ИЛ)-2-[4-((S)-ТЕТРАГІДРОФУРАН-3-ІЛОКСИ)-БЕНЗИЛ]-БЕНЗОЛУ, СПОСІБ ЇЇ ОДЕРЖАННЯ ТА ЇЇ ЗАСТОСУВАННЯ ПРИ ПРИГОТУВАННІ ЛІКАРСЬКИХ ЗАСОБІВ |
| US7723309B2 (en) | 2005-05-03 | 2010-05-25 | Boehringer Ingelheim International Gmbh | Crystalline forms of 1-chloro-4-(β-D-glucopyranos-1-yl)-2-[4-((R)-tetrahydrofuran-3-yloxy)-benzyl]-benzene, a method for its preparation and the use thereof for preparing medicaments |
| US7772191B2 (en) | 2005-05-10 | 2010-08-10 | Boehringer Ingelheim International Gmbh | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein |
| WO2007014894A2 (en) | 2005-07-27 | 2007-02-08 | Boehringer Ingelheim International Gmbh | Glucopyranosyl-substituted ( (hetero) cycloalyklethynyl-benzyl) -benzene derivatives and use thereof as sodium-dependent glucose cotransporter (sglt) inhibitors |
| DE602006017566D1 (de) | 2005-08-30 | 2010-11-25 | Boehringer Ingelheim Pharma | Glucopyranosyl-substituierte benzyl-derivate, medikamente mit solchen verbindungen, ihre verwendung und herstellungsverfahren dafür |
| RU2008113050A (ru) | 2005-09-08 | 2009-10-20 | БЕРИНГЕР ИНГЕЛЬХАЙМ ИНТЕРНАЦИОНАЛЬ ГмбХ (DE) | КРИСТАЛЛИЧЕСКИЕ ФОРМЫ 1-ХЛОР-4-(β-D-ГЛЮКОПИРАНОЗ-1-ИЛ)-2-(4-ЭТИНИЛБЕНЗИН)-БЕНЗОЛА, СПОСОБ ЕГО ПОЛУЧЕНИЯ И ЕГО ПРИМЕНЕНИЕ ДЛЯ ПРИГОТОВЛЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ |
| AR056195A1 (es) | 2005-09-15 | 2007-09-26 | Boehringer Ingelheim Int | Procedimientos para preparar derivados de (etinil-bencil)-benceno sustituidos de glucopiranosilo y compuestos intermedios de los mismos |
| EA200801773A1 (ru) | 2006-02-15 | 2009-02-27 | Бёрингер Ингельхайм Интернациональ Гмбх | Глюкопиранозилзамещенные производные бензонитрила, фармацевтические композиции, содержащие такие соединения, их применение и способ их получения |
| PE20080697A1 (es) | 2006-05-03 | 2008-08-05 | Boehringer Ingelheim Int | Derivados de benzonitrilo sustituidos con glucopiranosilo, composiciones farmaceuticas que contienen compuestos de este tipo, su uso y procedimiento para su fabricacion |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| TWI432446B (zh) | 2006-07-27 | 2014-04-01 | Chugai Pharmaceutical Co Ltd | 稠環螺酮縮醇衍生物、及其做為糖尿病治療藥之使用 |
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- 2005-03-03 CA CA2557320A patent/CA2557320C/en not_active Expired - Fee Related
- 2005-03-03 US US10/591,403 patent/US7732596B2/en not_active Expired - Fee Related
- 2005-03-03 ZA ZA200606792A patent/ZA200606792B/xx unknown
- 2005-03-03 RU RU2006131552/04A patent/RU2387663C2/ru not_active IP Right Cessation
- 2005-03-03 AU AU2005219777A patent/AU2005219777B2/en not_active Ceased
- 2005-03-03 PL PL381247A patent/PL381247A1/pl not_active Application Discontinuation
- 2005-03-03 NZ NZ549219A patent/NZ549219A/en not_active IP Right Cessation
- 2005-03-03 EP EP05720423A patent/EP1724277A4/en not_active Withdrawn
- 2005-03-03 CN CN2005800062115A patent/CN1934122B/zh not_active Expired - Fee Related
- 2005-03-03 WO PCT/JP2005/004152 patent/WO2005085265A1/ja not_active Ceased
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- 2005-03-04 TW TW094106585A patent/TW200540167A/zh not_active IP Right Cessation
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- 2006-08-16 IL IL177513A patent/IL177513A/en not_active IP Right Cessation
- 2006-09-20 KR KR1020067019362A patent/KR101214433B1/ko not_active Expired - Fee Related
- 2006-09-29 NO NO20064412A patent/NO20064412L/no not_active Application Discontinuation
- 2006-10-02 MA MA29361A patent/MA28512B1/fr unknown
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| JP2003012686A (ja) * | 2001-07-02 | 2003-01-15 | Kyowa Hakko Kogyo Co Ltd | ピラゾール誘導体 |
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Also Published As
| Publication number | Publication date |
|---|---|
| MA28512B1 (fr) | 2007-04-03 |
| US7732596B2 (en) | 2010-06-08 |
| CN1934122A (zh) | 2007-03-21 |
| KR101214433B1 (ko) | 2012-12-21 |
| CA2557320C (en) | 2013-02-05 |
| PL381247A1 (pl) | 2007-05-14 |
| EP1724277A1 (en) | 2006-11-22 |
| HK1099556A1 (zh) | 2007-08-17 |
| AU2005219777B2 (en) | 2011-02-03 |
| RU2387663C2 (ru) | 2010-04-27 |
| AU2005219777A1 (en) | 2005-09-15 |
| RU2006131552A (ru) | 2008-03-10 |
| KR20060132737A (ko) | 2006-12-21 |
| ZA200606792B (en) | 2007-12-27 |
| TW200540167A (en) | 2005-12-16 |
| NO20064412L (no) | 2006-12-04 |
| IL177513A (en) | 2011-11-30 |
| CN1934122B (zh) | 2010-08-04 |
| CA2557320A1 (en) | 2005-09-15 |
| NZ549219A (en) | 2010-08-27 |
| EP1724277A4 (en) | 2012-05-02 |
| TWI361190B (enExample) | 2012-04-01 |
| IL177513A0 (en) | 2006-12-10 |
| US20070197449A1 (en) | 2007-08-23 |
| WO2005085265A1 (ja) | 2005-09-15 |
| JPWO2005085265A1 (ja) | 2008-01-17 |
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