JP5037343B2 - 核酸分析方法 - Google Patents

核酸分析方法 Download PDF

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Publication number
JP5037343B2
JP5037343B2 JP2007527745A JP2007527745A JP5037343B2 JP 5037343 B2 JP5037343 B2 JP 5037343B2 JP 2007527745 A JP2007527745 A JP 2007527745A JP 2007527745 A JP2007527745 A JP 2007527745A JP 5037343 B2 JP5037343 B2 JP 5037343B2
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nucleic acid
template
complex
reaction mixture
nucleotide
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Japanese (ja)
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JP2008502369A5 (https=
JP2008502369A (ja
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フラー，カール・ダブリュ
ネルソン，ジョン・アール
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Global Life Sciences Solutions USA LLC
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Amersham Biosciences Corp
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2007527745A 2004-06-10 2005-06-09 核酸分析方法 Expired - Lifetime JP5037343B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57878904P 2004-06-10 2004-06-10
US60/578,789 2004-06-10
PCT/US2005/020378 WO2005123957A2 (en) 2004-06-10 2005-06-09 Method for nucleic acid analysis

Publications (3)

Publication Number Publication Date
JP2008502369A JP2008502369A (ja) 2008-01-31
JP2008502369A5 JP2008502369A5 (https=) 2008-08-21
JP5037343B2 true JP5037343B2 (ja) 2012-09-26

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JP2007527745A Expired - Lifetime JP5037343B2 (ja) 2004-06-10 2005-06-09 核酸分析方法

Country Status (9)

Country Link
US (1) US7871771B2 (https=)
EP (1) EP1766075B1 (https=)
JP (1) JP5037343B2 (https=)
CN (1) CN101120098A (https=)
AT (1) ATE461293T1 (https=)
AU (1) AU2005254984B2 (https=)
CA (1) CA2567591C (https=)
DE (1) DE602005020011D1 (https=)
WO (1) WO2005123957A2 (https=)

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US20100036110A1 (en) * 2008-08-08 2010-02-11 Xiaoliang Sunney Xie Methods and compositions for continuous single-molecule nucleic acid sequencing by synthesis with fluorogenic nucleotides
WO2010141391A2 (en) 2009-06-05 2010-12-09 Life Technologies Corporation Mutant dna polymerases
US9399217B2 (en) 2010-10-04 2016-07-26 Genapsys, Inc. Chamber free nanoreactor system
NZ610129A (en) 2010-10-04 2014-08-29 Genapsys Inc Systems and methods for automated reusable parallel biological reactions
US9184099B2 (en) 2010-10-04 2015-11-10 The Board Of Trustees Of The Leland Stanford Junior University Biosensor devices, systems and methods therefor
US8585973B2 (en) 2011-05-27 2013-11-19 The Board Of Trustees Of The Leland Stanford Junior University Nano-sensor array
KR101940833B1 (ko) * 2011-05-27 2019-01-21 제납시스 인크. 유전자 및 생물학적 분석을 위한 시스템 및 방법
US9926596B2 (en) 2011-05-27 2018-03-27 Genapsys, Inc. Systems and methods for genetic and biological analysis
US10093975B2 (en) 2011-12-01 2018-10-09 Genapsys, Inc. Systems and methods for high efficiency electronic sequencing and detection
WO2013096692A1 (en) 2011-12-21 2013-06-27 Illumina, Inc. Apparatus and methods for kinetic analysis and determination of nucleic acid sequences
EP2844774B1 (en) 2012-05-02 2018-07-18 Ibis Biosciences, Inc. Dna sequencing
EP2844775B1 (en) 2012-05-02 2018-07-18 Ibis Biosciences, Inc. Dna sequencing
WO2013166303A1 (en) 2012-05-02 2013-11-07 Ibis Biosciences, Inc. Dna sequencing
EP2971141B1 (en) 2013-03-15 2018-11-28 Genapsys, Inc. Systems for biological analysis
WO2015089238A1 (en) 2013-12-11 2015-06-18 Genapsys, Inc. Systems and methods for biological analysis and computation
US9822401B2 (en) 2014-04-18 2017-11-21 Genapsys, Inc. Methods and systems for nucleic acid amplification
US10077470B2 (en) 2015-07-21 2018-09-18 Omniome, Inc. Nucleic acid sequencing methods and systems
KR102254451B1 (ko) * 2016-04-22 2021-05-20 옴니옴 인코포레이티드 뉴클레오타이드-특이적 삼원 복합체 형성의 향상된 검출을 사용하는 핵산 서열 결정 방법 및 시스템
CA3022431C (en) 2016-04-29 2023-03-21 Omniome, Inc. Method of nucleic acid sequence determination
EP3449012B1 (en) 2016-04-29 2020-12-23 Omniome, Inc. Sequencing method employing ternary complex destabilization to identify cognate nucleotides
WO2018017884A1 (en) 2016-07-20 2018-01-25 Genapsys, Inc. Systems and methods for nucleic acid sequencing
US10428378B2 (en) 2016-08-15 2019-10-01 Omniome, Inc. Sequencing method for rapid identification and processing of cognate nucleotide pairs
KR102230444B1 (ko) 2016-08-15 2021-03-23 옴니옴 인코포레이티드 핵산을 시퀀싱하기 위한 방법 및 시스템
WO2018065299A1 (en) * 2016-10-05 2018-04-12 F. Hoffmann-La Roche Ag Nucleic acid sequencing using nanotransistors
EP3564387A4 (en) * 2016-12-27 2020-10-07 EGI Tech (Shen Zhen) Co., Limited UNIQUE FLUORESCENT DYE SEQUENCING PROCESS
US11248254B2 (en) 2016-12-30 2022-02-15 Omniome, Inc. Method and system employing distinguishable polymerases for detecting ternary complexes and identifying cognate nucleotides
US10975427B2 (en) 2017-01-20 2021-04-13 Omniome, Inc. Process for cognate nucleotide detection in a nucleic acid sequencing workflow
US10737267B2 (en) 2017-04-04 2020-08-11 Omniome, Inc. Fluidic apparatus and methods useful for chemical and biological reactions
US9951385B1 (en) 2017-04-25 2018-04-24 Omniome, Inc. Methods and apparatus that increase sequencing-by-binding efficiency
US10161003B2 (en) 2017-04-25 2018-12-25 Omniome, Inc. Methods and apparatus that increase sequencing-by-binding efficiency
WO2019060628A1 (en) 2017-09-21 2019-03-28 Genapsys, Inc. SYSTEMS AND METHODS FOR NUCLEIC ACID SEQUENCING
WO2019079593A1 (en) 2017-10-19 2019-04-25 Omniome, Inc. BACKGROUND NOISE REDUCTION AND STABILIZATION OF SIMULTANEOUS COMPLEXES IN LINKED ASSAY WORKFLOWS
CN112567048B (zh) 2018-07-24 2026-01-23 加利福尼亚太平洋生物科学股份有限公司 三元复合物种类的连续形成
EP3853358A1 (en) 2018-09-17 2021-07-28 Omniome, Inc. Engineered polymerases for improved sequencing
GB2613480B (en) 2018-11-15 2023-11-22 Element Biosciences Inc Methods for generating circular nucleic acid molecules
US12391929B2 (en) 2019-05-24 2025-08-19 Element Biosciences, Inc. Polymerase-nucleotide conjugates for sequencing by trapping
US20220251638A1 (en) * 2019-05-27 2022-08-11 Universal Sequencing Technology Corporation Methods to Identify Components in Nucleic Acid Sequences
WO2021092431A1 (en) 2019-11-08 2021-05-14 Omniome, Inc. Engineered polymerases for improved sequencing by binding
CA3178970A1 (en) * 2020-05-20 2021-11-25 Sinan ARSLAN Methods for paired-end sequencing library preparation

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WO1998045474A1 (en) * 1997-04-04 1998-10-15 Innogenetics N.V. Isothermal polymerase chain reaction by cycling the concentration of divalent metal ions
ATE371022T1 (de) * 1998-06-17 2007-09-15 Ge Healthcare Bio Sciences Fy7 polymerase
CN1197975C (zh) * 1998-08-19 2005-04-20 生物风险公司 测定多核苷酸序列变异的方法
GB9901475D0 (en) * 1999-01-22 1999-03-17 Pyrosequencing Ab A method of DNA sequencing
US20030108867A1 (en) 1999-04-20 2003-06-12 Chee Mark S Nucleic acid sequencing using microsphere arrays
US6274320B1 (en) * 1999-09-16 2001-08-14 Curagen Corporation Method of sequencing a nucleic acid
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US6613523B2 (en) * 2001-06-29 2003-09-02 Agilent Technologies, Inc. Method of DNA sequencing using cleavable tags
US7169560B2 (en) * 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
US7264934B2 (en) * 2004-06-10 2007-09-04 Ge Healthcare Bio-Sciences Corp. Rapid parallel nucleic acid analysis

Also Published As

Publication number Publication date
EP1766075A2 (en) 2007-03-28
WO2005123957A3 (en) 2006-05-18
CN101120098A (zh) 2008-02-06
DE602005020011D1 (de) 2010-04-29
CA2567591A1 (en) 2005-12-29
CA2567591C (en) 2011-08-02
US7871771B2 (en) 2011-01-18
WO2005123957A2 (en) 2005-12-29
ATE461293T1 (de) 2010-04-15
US20080287305A1 (en) 2008-11-20
EP1766075B1 (en) 2010-03-17
AU2005254984A1 (en) 2005-12-29
JP2008502369A (ja) 2008-01-31
EP1766075A4 (en) 2008-05-21
AU2005254984B2 (en) 2008-10-16

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