JP5010683B2 - 心臓血管機能を調節する経皮神経刺激装置 - Google Patents
心臓血管機能を調節する経皮神経刺激装置 Download PDFInfo
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- JP5010683B2 JP5010683B2 JP2009532482A JP2009532482A JP5010683B2 JP 5010683 B2 JP5010683 B2 JP 5010683B2 JP 2009532482 A JP2009532482 A JP 2009532482A JP 2009532482 A JP2009532482 A JP 2009532482A JP 5010683 B2 JP5010683 B2 JP 5010683B2
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/36017—External stimulators, e.g. with patch electrodes with leads or electrodes penetrating the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
- A61N1/36031—Control systems using physiological parameters for adjustment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
- A61N1/36034—Control systems specified by the stimulation parameters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36114—Cardiac control, e.g. by vagal stimulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37252—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37252—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data
- A61N1/37288—Communication to several implantable medical devices within one patient
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Cardiology (AREA)
- Physiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/548,348 US7797046B2 (en) | 2006-10-11 | 2006-10-11 | Percutaneous neurostimulator for modulating cardiovascular function |
| US11/548,348 | 2006-10-11 | ||
| PCT/US2007/071283 WO2008045597A1 (en) | 2006-10-11 | 2007-06-15 | Percutaneous neurostimulator for modulating cardiovascular function |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010506617A JP2010506617A (ja) | 2010-03-04 |
| JP2010506617A5 JP2010506617A5 (enExample) | 2010-07-08 |
| JP5010683B2 true JP5010683B2 (ja) | 2012-08-29 |
Family
ID=38561725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009532482A Expired - Fee Related JP5010683B2 (ja) | 2006-10-11 | 2007-06-15 | 心臓血管機能を調節する経皮神経刺激装置 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US7797046B2 (enExample) |
| EP (2) | EP2094353A1 (enExample) |
| JP (1) | JP5010683B2 (enExample) |
| WO (1) | WO2008045597A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8396556B2 (en) | 2006-10-11 | 2013-03-12 | Cardiac Pacemakers, Inc. | Transcutaneous neurostimulator for treating hypertension |
| RU208292U1 (ru) * | 2021-08-27 | 2021-12-13 | Федеральное государственное автономное образовательное учреждение высшего образования «Российский национальный исследовательский медицинский университет имени Н.И. Пирогова» Министерства здравоохранения Российской Федерации | Электрораздражитель для исследования суправитальных реакций |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9050469B1 (en) | 2003-11-26 | 2015-06-09 | Flint Hills Scientific, Llc | Method and system for logging quantitative seizure information and assessing efficacy of therapy using cardiac signals |
| US10441780B2 (en) * | 2005-11-10 | 2019-10-15 | Electrocore, Inc. | Systems and methods for vagal nerve stimulation |
| US7797046B2 (en) | 2006-10-11 | 2010-09-14 | Cardiac Pacemakers, Inc. | Percutaneous neurostimulator for modulating cardiovascular function |
| US20080091255A1 (en) * | 2006-10-11 | 2008-04-17 | Cardiac Pacemakers | Implantable neurostimulator for modulating cardiovascular function |
| US8571643B2 (en) | 2010-09-16 | 2013-10-29 | Flint Hills Scientific, Llc | Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex |
| US8382667B2 (en) | 2010-10-01 | 2013-02-26 | Flint Hills Scientific, Llc | Detecting, quantifying, and/or classifying seizures using multimodal data |
| US8337404B2 (en) | 2010-10-01 | 2012-12-25 | Flint Hills Scientific, Llc | Detecting, quantifying, and/or classifying seizures using multimodal data |
| US8417344B2 (en) | 2008-10-24 | 2013-04-09 | Cyberonics, Inc. | Dynamic cranial nerve stimulation based on brain state determination from cardiac data |
| US9375571B2 (en) * | 2013-01-15 | 2016-06-28 | ElectroCore, LLC | Mobile phone using non-invasive nerve stimulation |
| US8239028B2 (en) | 2009-04-24 | 2012-08-07 | Cyberonics, Inc. | Use of cardiac parameters in methods and systems for treating a chronic medical condition |
| US8827912B2 (en) | 2009-04-24 | 2014-09-09 | Cyberonics, Inc. | Methods and systems for detecting epileptic events using NNXX, optionally with nonlinear analysis parameters |
| US8831732B2 (en) | 2010-04-29 | 2014-09-09 | Cyberonics, Inc. | Method, apparatus and system for validating and quantifying cardiac beat data quality |
| US8649871B2 (en) | 2010-04-29 | 2014-02-11 | Cyberonics, Inc. | Validity test adaptive constraint modification for cardiac data used for detection of state changes |
| US8562536B2 (en) | 2010-04-29 | 2013-10-22 | Flint Hills Scientific, Llc | Algorithm for detecting a seizure from cardiac data |
| US8679009B2 (en) | 2010-06-15 | 2014-03-25 | Flint Hills Scientific, Llc | Systems approach to comorbidity assessment |
| US9409036B2 (en) * | 2010-07-19 | 2016-08-09 | Wake Forest University Health Sciences | Implantable connector systems having magnetic portions thereon and related methods |
| US8641646B2 (en) | 2010-07-30 | 2014-02-04 | Cyberonics, Inc. | Seizure detection using coordinate data |
| US9750945B2 (en) * | 2010-08-02 | 2017-09-05 | St. Jude Medical Luxembourg Holdings SMI S.A.R.L. | Neurostimulation programmers with improved RF antenna radiation patterns |
| US8684921B2 (en) | 2010-10-01 | 2014-04-01 | Flint Hills Scientific Llc | Detecting, assessing and managing epilepsy using a multi-variate, metric-based classification analysis |
| EP2665457B1 (en) * | 2011-01-21 | 2019-06-12 | Carewave Medical, Inc. | Modular stimulus applicator system |
| US9504390B2 (en) | 2011-03-04 | 2016-11-29 | Globalfoundries Inc. | Detecting, assessing and managing a risk of death in epilepsy |
| US8725239B2 (en) | 2011-04-25 | 2014-05-13 | Cyberonics, Inc. | Identifying seizures using heart rate decrease |
| US9402550B2 (en) | 2011-04-29 | 2016-08-02 | Cybertronics, Inc. | Dynamic heart rate threshold for neurological event detection |
| US9114261B2 (en) * | 2011-10-20 | 2015-08-25 | Ams Research Corporation | Electrical stimulation device having remote access |
| US10448839B2 (en) | 2012-04-23 | 2019-10-22 | Livanova Usa, Inc. | Methods, systems and apparatuses for detecting increased risk of sudden death |
| WO2013162709A1 (en) | 2012-04-26 | 2013-10-31 | Medtronic, Inc. | Trial stimulation systems |
| WO2013162708A2 (en) | 2012-04-26 | 2013-10-31 | Medtronic, Inc. | Trial stimulation systems |
| US9878168B2 (en) | 2012-04-26 | 2018-01-30 | Medtronic, Inc. | Trial stimulation systems |
| US11771888B2 (en) | 2012-06-26 | 2023-10-03 | Exoneural Network Ab | Medical therapy arrangement for applying an electrical stimulation to a human or animal subject |
| SE1250685A1 (sv) * | 2012-06-26 | 2013-12-27 | Inerventions Ab | Medicinskt terapiarrangemang |
| US10987508B2 (en) | 2012-06-26 | 2021-04-27 | Inerventions Ab | Medical therapy arrangement for applying an electrical stimulation to a human or animal subject |
| US10220211B2 (en) | 2013-01-22 | 2019-03-05 | Livanova Usa, Inc. | Methods and systems to diagnose depression |
| WO2014186621A1 (en) * | 2013-05-15 | 2014-11-20 | Ripple Llc | Systems and methods for electrical stimulation of neural tissue |
| WO2016025909A1 (en) | 2014-08-15 | 2016-02-18 | Axonics Modulation Technologies, Inc. | External pulse generator device and associated methods for trial nerve stimulation |
| WO2016038713A1 (ja) * | 2014-09-11 | 2016-03-17 | オリンパス株式会社 | 神経刺激装置、神経刺激システム及び神経刺激方法 |
| EP3204112A1 (en) | 2014-10-07 | 2017-08-16 | Boston Scientific Neuromodulation Corporation | Systems, devices, and methods for electrical stimulation using feedback to adjust stimulation parameters |
| CN107073262B (zh) * | 2014-10-31 | 2021-01-05 | 阿文特公司 | 非侵入式神经刺激系统 |
| US20220062621A1 (en) | 2015-02-24 | 2022-03-03 | Elira, Inc. | Electrical Stimulation-Based Weight Management System |
| US10143840B2 (en) | 2015-02-24 | 2018-12-04 | Elira, Inc. | Systems and methods for enabling appetite modulation and/or improving dietary compliance using an electro-dermal patch |
| US9956393B2 (en) | 2015-02-24 | 2018-05-01 | Elira, Inc. | Systems for increasing a delay in the gastric emptying time for a patient using a transcutaneous electro-dermal patch |
| US10335302B2 (en) | 2015-02-24 | 2019-07-02 | Elira, Inc. | Systems and methods for using transcutaneous electrical stimulation to enable dietary interventions |
| US10864367B2 (en) | 2015-02-24 | 2020-12-15 | Elira, Inc. | Methods for using an electrical dermal patch in a manner that reduces adverse patient reactions |
| US10765863B2 (en) | 2015-02-24 | 2020-09-08 | Elira, Inc. | Systems and methods for using a transcutaneous electrical stimulation device to deliver titrated therapy |
| WO2016137926A1 (en) * | 2015-02-24 | 2016-09-01 | Creasey Graham H | Topical nerve stimulator and sensor for control of autonomic function |
| US10376145B2 (en) | 2015-02-24 | 2019-08-13 | Elira, Inc. | Systems and methods for enabling a patient to achieve a weight loss objective using an electrical dermal patch |
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| WO2017208168A2 (en) * | 2016-05-31 | 2017-12-07 | Lab Schöpfergeist Ag | Strap arrangement for a nerve stimulator |
| CN112533561B (zh) | 2018-03-07 | 2023-10-27 | Soovu实验室公司 | 用于通过刺激热觉纤维改善疼痛缓解的系统和方法 |
| US10471251B1 (en) | 2018-07-31 | 2019-11-12 | Manicka Institute Llc | Subcutaneous device for monitoring and/or providing therapies |
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| US11660444B2 (en) | 2018-07-31 | 2023-05-30 | Manicka Institute Llc | Resilient body component contact for a subcutaneous device |
| US11433233B2 (en) | 2020-11-25 | 2022-09-06 | Calyan Technologies, Inc. | Electrode contact for a subcutaneous device |
| US11717674B2 (en) | 2018-07-31 | 2023-08-08 | Manicka Institute Llc | Subcutaneous device for use with remote device |
| US10576291B2 (en) | 2018-07-31 | 2020-03-03 | Manicka Institute Llc | Subcutaneous device |
| US11179571B2 (en) | 2018-07-31 | 2021-11-23 | Manicka Institute Llc | Subcutaneous device for monitoring and/or providing therapies |
| US10716511B2 (en) | 2018-07-31 | 2020-07-21 | Manicka Institute Llc | Subcutaneous device for monitoring and/or providing therapies |
| US11266834B2 (en) * | 2018-09-28 | 2022-03-08 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Electro-acupuncture (EA) system having a wearable electro-acupuncture neurostimulator for enhanced clinical and scientific outcomes, and a method |
| US20240131324A1 (en) * | 2019-03-18 | 2024-04-25 | Exoneural Network Ab | Medical therapy arrangement for applying an electrical stimulation to a human or animal subject |
| US10987060B1 (en) | 2020-09-14 | 2021-04-27 | Calyan Technologies, Inc. | Clip design for a subcutaneous device |
| EP4291294A1 (en) | 2021-04-27 | 2023-12-20 | Boston Scientific Neuromodulation Corporation | Systems and methods for automated programming of electrical stimulation |
| US12403313B2 (en) | 2021-06-15 | 2025-09-02 | Boston Scientific Neuromodulation Corporation | Methods and systems for estimating neural activation by stimulation using a stimulation system |
| EP4415809A2 (en) | 2021-12-10 | 2024-08-21 | Boston Scientific Neuromodulation Corporation | Systems and methods for generating and using response maps for electrical stimulation |
| EP4501397A4 (en) * | 2022-03-28 | 2025-10-15 | Beijing Leading Innovation Medical Valley Co Ltd | Nerve electrostimulation system with capacitive coupling energy transfer, in-vivo nerve electrostimulator and in-vitro energy control therefor |
Family Cites Families (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE346468B (enExample) | 1969-02-24 | 1972-07-10 | Lkb Medical Ab | |
| US3938526A (en) * | 1974-05-20 | 1976-02-17 | Anderson Weston A | Electrical acupuncture needle heater |
| US4690144A (en) * | 1982-04-02 | 1987-09-01 | Medtronic, Inc. | Wireless transcutaneous electrical tissue stimulator |
| GB8406509D0 (en) * | 1984-03-13 | 1984-04-18 | Bio Medical Res Ltd | Electrical stimulation of muscle |
| JPH0626593B2 (ja) * | 1985-09-19 | 1994-04-13 | オムロン株式会社 | 低周波治療器 |
| US5211175A (en) * | 1988-11-07 | 1993-05-18 | Regents Of The University Of California | Method for implanting electra-acupuncture needle |
| US5335657A (en) * | 1991-05-03 | 1994-08-09 | Cyberonics, Inc. | Therapeutic treatment of sleep disorder by nerve stimulation |
| US5193539A (en) * | 1991-12-18 | 1993-03-16 | Alfred E. Mann Foundation For Scientific Research | Implantable microstimulator |
| US5487759A (en) * | 1993-06-14 | 1996-01-30 | Bastyr; Charles A. | Nerve stimulating device and associated support device |
| US5540734A (en) * | 1994-09-28 | 1996-07-30 | Zabara; Jacob | Cranial nerve stimulation treatments using neurocybernetic prosthesis |
| US5571150A (en) * | 1994-12-19 | 1996-11-05 | Cyberonics, Inc. | Treatment of patients in coma by nerve stimulation |
| US5707400A (en) | 1995-09-19 | 1998-01-13 | Cyberonics, Inc. | Treating refractory hypertension by nerve stimulation |
| US6449507B1 (en) * | 1996-04-30 | 2002-09-10 | Medtronic, Inc. | Method and system for nerve stimulation prior to and during a medical procedure |
| US6246912B1 (en) * | 1996-06-27 | 2001-06-12 | Sherwood Services Ag | Modulated high frequency tissue modification |
| JPH1133126A (ja) * | 1997-07-14 | 1999-02-09 | Ryuzo Nagayama | 心搏同期刺激電気治療器 |
| US6057758A (en) * | 1998-05-20 | 2000-05-02 | Hewlett-Packard Company | Handheld clinical terminal |
| US6594527B2 (en) | 1998-09-18 | 2003-07-15 | Nexmed Holdings, Inc. | Electrical stimulation apparatus and method |
| US6269270B1 (en) * | 1998-10-26 | 2001-07-31 | Birinder Bob Boveja | Apparatus and method for adjunct (add-on) therapy of Dementia and Alzheimer's disease utilizing an implantable lead and external stimulator |
| US6208902B1 (en) * | 1998-10-26 | 2001-03-27 | Birinder Bob Boveja | Apparatus and method for adjunct (add-on) therapy for pain syndromes utilizing an implantable lead and an external stimulator |
| US6106477A (en) | 1998-12-28 | 2000-08-22 | Medtronic, Inc. | Chronically implantable blood vessel cuff with sensor |
| US6169924B1 (en) * | 1999-04-27 | 2001-01-02 | T. Stuart Meloy | Spinal cord stimulation |
| US6178352B1 (en) * | 1999-05-07 | 2001-01-23 | Woodside Biomedical, Inc. | Method of blood pressure moderation |
| US6445955B1 (en) | 1999-07-08 | 2002-09-03 | Stephen A. Michelson | Miniature wireless transcutaneous electrical neuro or muscular-stimulation unit |
| US6516227B1 (en) | 1999-07-27 | 2003-02-04 | Advanced Bionics Corporation | Rechargeable spinal cord stimulator system |
| US6553263B1 (en) * | 1999-07-30 | 2003-04-22 | Advanced Bionics Corporation | Implantable pulse generators using rechargeable zero-volt technology lithium-ion batteries |
| US6450942B1 (en) | 1999-08-20 | 2002-09-17 | Cardiorest International Ltd. | Method for reducing heart loads in mammals |
| DE10053118A1 (de) * | 1999-10-29 | 2001-05-31 | Medtronic Inc | Apparat und Verfahren zur Selbstidentifizierung aus der Ferne von Komponenten in medizinischen Vorrichtungssystemen |
| US6539264B1 (en) * | 1999-12-01 | 2003-03-25 | Vertis Neuroscience, Inc. | Percutaneous electrical therapy system with sharp point protection |
| US6493592B1 (en) * | 1999-12-01 | 2002-12-10 | Vertis Neuroscience, Inc. | Percutaneous electrical therapy system with electrode position maintenance |
| US6522927B1 (en) * | 1999-12-01 | 2003-02-18 | Vertis Neuroscience, Inc. | Electrode assembly for a percutaneous electrical therapy system |
| US6556869B1 (en) * | 1999-12-01 | 2003-04-29 | Vertis Neuroscience, Inc. | Electrode introducer for a percutaneous electrical therapy system |
| US7403821B2 (en) * | 2000-02-17 | 2008-07-22 | Neurodan A/S | Method and implantable systems for neural sensing and nerve stimulation |
| EP1330287B1 (en) * | 2000-10-26 | 2009-07-29 | Medtronic, Inc. | Apparatus to minimize the effects of a cardiac insult |
| CA2432540C (en) * | 2000-11-07 | 2008-06-10 | Research In Motion Limited | Communication device with multiple detachable communication modules |
| US6567695B1 (en) * | 2000-11-24 | 2003-05-20 | Woodside Biomedical, Inc. | Electro-acupuncture device with stimulation electrode assembly |
| US6577898B2 (en) * | 2001-04-26 | 2003-06-10 | Pacesetter, Inc. | Bi-directional telemetry system and method for transmitting data at high transmission rate |
| US6735480B2 (en) * | 2001-06-29 | 2004-05-11 | Abbott Laboratories | Electro-acupuncture device with D-shaped stimulation electrodes |
| US6622047B2 (en) * | 2001-07-28 | 2003-09-16 | Cyberonics, Inc. | Treatment of neuropsychiatric disorders by near-diaphragmatic nerve stimulation |
| US6842645B2 (en) * | 2001-11-09 | 2005-01-11 | Pacesetter, Inc. | Presentation architecture for network supporting implantable cardiac therapy device |
| US7191012B2 (en) * | 2003-05-11 | 2007-03-13 | Boveja Birinder R | Method and system for providing pulsed electrical stimulation to a craniel nerve of a patient to provide therapy for neurological and neuropsychiatric disorders |
| US20060004423A1 (en) * | 2002-05-09 | 2006-01-05 | Boveja Birinder R | Methods and systems to provide therapy or alleviate symptoms of chronic headache, transformed migraine, and occipital neuralgia by providing rectangular and/or complex electrical pulses to occipital nerves |
| US7041061B2 (en) * | 2002-07-19 | 2006-05-09 | Cardiac Pacemakers, Inc. | Method and apparatus for quantification of cardiac wall motion asynchrony |
| US7089061B2 (en) * | 2002-08-27 | 2006-08-08 | Abbott Laboratories | Device and method for nausea suppression |
| US20040102818A1 (en) | 2002-11-26 | 2004-05-27 | Hakky Said I. | Method and system for controlling blood pressure |
| JP2006509593A (ja) * | 2002-12-16 | 2006-03-23 | メーガン メディカル アイエヌシー | 深経皮的利用に関するデプス制御のための方法及び器具 |
| JP2006509605A (ja) * | 2002-12-16 | 2006-03-23 | メーガン メディカル アイエヌシー | 電気的なカップリングを備えた深経皮的な装置 |
| US7321792B1 (en) * | 2003-03-19 | 2008-01-22 | Pacesetter, Inc. | Pacing therapy and acupuncture |
| US7155278B2 (en) * | 2003-04-21 | 2006-12-26 | Medtronic, Inc. | Neurostimulation to treat effects of sleep apnea |
| US7444184B2 (en) * | 2003-05-11 | 2008-10-28 | Neuro And Cardial Technologies, Llc | Method and system for providing therapy for bulimia/eating disorders by providing electrical pulses to vagus nerve(s) |
| US7263405B2 (en) * | 2003-08-27 | 2007-08-28 | Neuro And Cardiac Technologies Llc | System and method for providing electrical pulses to the vagus nerve(s) to provide therapy for obesity, eating disorders, neurological and neuropsychiatric disorders with a stimulator, comprising bi-directional communication and network capabilities |
| WO2005079295A2 (en) * | 2004-02-12 | 2005-09-01 | Ndi Medical, Llc | Portable assemblies, systems and methods for providing functional or therapeutic neuromuscular stimulation |
| WO2005084389A2 (en) | 2004-03-02 | 2005-09-15 | Cvrx, Inc. | External baroreflex activation |
| US7239918B2 (en) * | 2004-06-10 | 2007-07-03 | Ndi Medical Inc. | Implantable pulse generator for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue |
| US20070067000A1 (en) * | 2004-06-10 | 2007-03-22 | Ndi Medical, Llc | Implantable pulse generator systems and methods for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue |
| US20050283202A1 (en) * | 2004-06-22 | 2005-12-22 | Gellman Barry N | Neuromodulation system |
| US7672733B2 (en) * | 2004-10-29 | 2010-03-02 | Medtronic, Inc. | Methods and apparatus for sensing cardiac activity via neurological stimulation therapy system or medical electrical lead |
| US9089691B2 (en) * | 2004-12-07 | 2015-07-28 | Cardiac Pacemakers, Inc. | Stimulator for auricular branch of vagus nerve |
| DE102005014586A1 (de) * | 2005-02-08 | 2006-08-10 | Ns Welltec Gmbh | System zur Stimulation von Akupunkturpunkten |
| US7231256B2 (en) * | 2005-03-11 | 2007-06-12 | Medtronic, Inc. | Neurostimulation site screening |
| US8078278B2 (en) * | 2006-01-10 | 2011-12-13 | Remon Medical Technologies Ltd. | Body attachable unit in wireless communication with implantable devices |
| US20070265674A1 (en) * | 2006-04-27 | 2007-11-15 | Olson John C | Fault tolerant implantable sensors having redundant electrical grounding connections |
| US7797046B2 (en) | 2006-10-11 | 2010-09-14 | Cardiac Pacemakers, Inc. | Percutaneous neurostimulator for modulating cardiovascular function |
| US7797041B2 (en) | 2006-10-11 | 2010-09-14 | Cardiac Pacemakers, Inc. | Transcutaneous neurostimulator for modulating cardiovascular function |
-
2006
- 2006-10-11 US US11/548,348 patent/US7797046B2/en not_active Expired - Fee Related
-
2007
- 2007-06-15 EP EP07798601A patent/EP2094353A1/en not_active Withdrawn
- 2007-06-15 EP EP12153741A patent/EP2457616A1/en not_active Withdrawn
- 2007-06-15 WO PCT/US2007/071283 patent/WO2008045597A1/en not_active Ceased
- 2007-06-15 JP JP2009532482A patent/JP5010683B2/ja not_active Expired - Fee Related
-
2010
- 2010-08-26 US US12/869,579 patent/US8688211B2/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8396556B2 (en) | 2006-10-11 | 2013-03-12 | Cardiac Pacemakers, Inc. | Transcutaneous neurostimulator for treating hypertension |
| US8571687B2 (en) | 2006-10-11 | 2013-10-29 | Cardiac Pacemakers, Inc. | Transcutaneous neurostimulator for modulating cardiovascular function |
| RU208292U1 (ru) * | 2021-08-27 | 2021-12-13 | Федеральное государственное автономное образовательное учреждение высшего образования «Российский национальный исследовательский медицинский университет имени Н.И. Пирогова» Министерства здравоохранения Российской Федерации | Электрораздражитель для исследования суправитальных реакций |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008045597A1 (en) | 2008-04-17 |
| US20100324620A1 (en) | 2010-12-23 |
| EP2094353A1 (en) | 2009-09-02 |
| JP2010506617A (ja) | 2010-03-04 |
| US8688211B2 (en) | 2014-04-01 |
| EP2457616A1 (en) | 2012-05-30 |
| US20080091248A1 (en) | 2008-04-17 |
| US7797046B2 (en) | 2010-09-14 |
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