JP5004468B2 - Indoor dust mite repellent article - Google Patents
Indoor dust mite repellent article Download PDFInfo
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- JP5004468B2 JP5004468B2 JP2005373653A JP2005373653A JP5004468B2 JP 5004468 B2 JP5004468 B2 JP 5004468B2 JP 2005373653 A JP2005373653 A JP 2005373653A JP 2005373653 A JP2005373653 A JP 2005373653A JP 5004468 B2 JP5004468 B2 JP 5004468B2
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- JP
- Japan
- Prior art keywords
- indoor
- mite repellent
- mites
- repellent
- mite
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Catching Or Destruction (AREA)
- Cleaning Implements For Floors, Carpets, Furniture, Walls, And The Like (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Description
本発明は、屋内塵性ダニ忌避用物品に関するものである。 The present invention relates to an indoor dusty mite repellent article.
地球上には極めて多種のダニ類が生息し、例えば植物に寄生するミカンハダニ、ナミハダニ類等は農作物に多大な被害を与えている。これらの植物に寄生するダニの駆除を目的とした殺ダニ剤は古くから開発が進められており、また有望な新規化合物が次々と発見されている。
一方で、近年の居住環境の変化により、屋内にコナダニ、ヒョウヒダニ、ホコリダニ等の屋内塵性ダニ類が発生し、不快感を与えるばかりでなく、アレルギー性喘息や皮疹を惹起する等の問題を生じている。
そこで、カーペットや寝具等に処理するための屋内用殺ダニ剤が求められてきたが、植物に寄生するダニに対して有用な殺ダニ剤が必ずしも屋内塵性ダニ類に対して有効ではないという事情があった。これは、植物に寄生するダニ類が主に前気門類に属し、一方屋内に生息する塵性ダニ類が主に無気門類に属するという種属差に起因すると考えられている。また、屋内では直接肌に接触する使用場面が多いためにより安全性の高い薬剤の開発が必要とされ、更にアレルギー性喘息を引き起こすヒョウヒダニ類は、虫体の死骸そのものでもアレルギーの原因になることが明らかとなってきた。
A great variety of mites live on the earth. For example, citrus mites and nymph mites parasitizing plants cause great damage to crops. Acaricides aimed at controlling mites parasitic on these plants have been developed for a long time, and promising new compounds have been discovered one after another.
On the other hand, due to changes in the living environment in recent years, indoor dust mites such as mites, leopard mites, and dust mites are generated indoors, causing problems such as causing allergic asthma and skin rash as well as discomfort. ing.
Therefore, there has been a demand for an indoor acaricide for treating carpets, bedding, etc., but a useful acaricide against mites parasitic on plants is not necessarily effective against indoor dust mites. There was a situation. This is thought to be due to species differences in which mites parasitizing plants mainly belong to the anterior genus, while dust mites that live indoors mainly belong to the aerial genus. Also, because there are many use cases that directly contact the skin indoors, it is necessary to develop a safer drug. Further, leopard mites that cause allergic asthma can cause allergies even in the corpse of the worm body itself. It has become clear.
かかる状況を背景として、屋内塵性ダニ類を殺すのではなく、人や患者にダニを近づけないようにする技術も模索され、これまでにいくつかの提案がなされている。例えば、特開平３−２６４５０４号公報には、オイゲノールやｎ−ヘキシルベンゾエート等を有効成分とする殺ダニまたはダニ忌避剤が開示されている。また、特開平６−１６５１５号公報は、室内用ダニ防除剤の有効成分として、ベチバー油、パチョウリ油、クローブ油などの植物精油を、そして、特開２００１−３１５０８号公報は、１，８−シネオール、又はこの成分が多く含まれるユーカリオイルを開示し、天然産志向と安全性への配慮を謳っているが、屋内塵性ダニ類に対する忌避効果は満足するものとは言えない。
ところで、本願出願人は、以前に、酢酸シンナミルや桂皮酸メチル等（特開平３−８１２０２号公報）、ヘリオトロピンやアニスアルデヒド等（特開平３−９０００４号公報）、桂皮油（特開平３−１２３７１４号公報）を含有する屋内用殺ダニ剤を開示したが、この当時は殺ダニ剤を意図していたため、本発明の趣旨からいえば改良の余地を残したものであった。
更に、ダニアレルゲンを除去する方法として、例えば塩化ベンザルコニウム等の成分やセスキテルペンアルコール等を用いる方法が提案されている（それぞれ、特開２００１−３３５４７４号公報、特開２００３−２３８３９４号公報）。しかしながら、これらのアレルゲン低減化剤を施用するのみでは、アレルゲン低減化効果が十分でないうえ、ダニを遠ざける作用を有さないため、実用的な清潔環境をつくり得ないのが現状である。
By the way, the applicant of the present application previously mentioned cinnamyl acetate, methyl cinnamate and the like (Japanese Patent Laid-Open No. 3-81202), heliotropin and anisaldehyde (Japanese Patent Laid-Open No. No. 123714) was disclosed, but at that time it was intended to be an acaricide, so there was room for improvement in the spirit of the present invention.
Furthermore, as a method for removing mite allergens, for example, methods using components such as benzalkonium chloride and sesquiterpene alcohol have been proposed (JP 2001-335474 A and JP 2003-238394 A, respectively). . However, the application of these allergen reducing agents does not provide an allergen-reducing effect and does not have an action to keep ticks away, so that a practical clean environment cannot be created.
本発明は、居室、カーペットや寝具、畳やフロア等に安心して施用でき、しかも屋内塵性ダニ忌避成分の揮散作用ならびに接触作用により、コナダニ、ヒョウヒダニ、ホコリダニ、ツメダニ等などに対して優れた忌避効果を奏する屋内塵性ダニ忌避用物品を提供することを目的とする。 The present invention can be safely applied to living rooms, carpets, bedding, tatami mats, floors, etc., and has excellent repellent properties against dust mites, leopard mites, dust mites, claw mites, etc. due to the volatilizing action and contact action of indoor dust mite repellent ingredients. An object of the present invention is to provide an indoor dust mite repellent article that exhibits an effect.
上記目的を達成するため、本発明は以下の構成を採用する。
（１）屋内塵性ダニ忌避成分である酢酸シンナミル、桂皮酸ベンジル、桂皮酸メチル、桂皮酸エチル、桂皮アルデヒド、及び桂皮油から選ばれた１種又は２種以上を不織布製清掃シートに含浸させ、前記シート中の屋内塵性ダニ忌避成分もしくは清掃に伴い前記シートとの接触表面に移行した屋内塵性ダニ忌避成分の揮散作用ならびに接触作用により屋内塵性ダニを忌避させるようになした屋内塵性ダニ忌避用物品。
（２）屋内塵性ダニ忌避成分として、酢酸シンナミル、桂皮酸ベンジル、桂皮酸メチル、桂皮酸エチル、桂皮アルデヒド、及び桂皮油から選ばれた１種又は２種以上とともに、ベンズアルデヒド類、オイゲノール類、及び安息香酸ベンジルエステル類から選ばれた１種又は２種以上を含有する（１）記載の屋内塵性ダニ忌避用物品。
（３）屋内塵性ダニ忌避成分とともに、ダニアレルゲン低減化剤を含む（１）又は（２）の屋内塵性ダニ忌避用物品。
（４）不織布製清掃シートが、レーヨンを含むポリオレフィン繊維層と、その片面もしくは両面にポリエステル繊維層を交絡させてなる（１）記載の屋内塵性ダニ忌避用物品。
In order to achieve the above object, the present invention adopts the following configuration.
(1) A nonwoven cleaning sheet is impregnated with one or more selected from cinnamyl acetate, benzyl cinnamate, methyl cinnamate, ethyl cinnamate, cinnamate aldehyde, and cinnamon oil, which are indoor dust mite repellent ingredients. Indoor dust in which the indoor dust mites are repelled by the volatilization action and the contact action of the indoor dust mite repellent ingredient in the sheet or the indoor dust mite repellent ingredient transferred to the contact surface with the cleaning. Articles for repelling sex mites.
(2) As an indoor dusty mite repellent ingredient, cinnamyl acetate, benzyl cinnamate, methyl cinnamate, ethyl cinnamate, cinnamaldehyde, and cinnamon oil, as well as benzaldehydes, eugenols, and containing one or more selected from benzyl benzoate esters (1) Symbol placement of house dust mite repellent article.
(3) The indoor dust mite repellent article according to (1) or (2), which contains a mite allergen reducing agent together with an indoor dust mite repellent component.
(4) The indoor dusty mite repellent article according to (1), wherein the nonwoven fabric cleaning sheet has a polyolefin fiber layer containing rayon entangled with a polyester fiber layer on one or both sides thereof.
本発明の屋内塵性ダニ忌避用物品は、居室、カーペットや寝具、畳やフロア等に安心して施用でき、しかも屋内塵性ダニ忌避成分の揮散作用ならびに接触作用により、コナダニ、ヒョウヒダニ、ホコリダニ、ツメダニ等などに対して優れた忌避効果を奏するので極めて実用的である。 The indoor dust mite repellent article of the present invention can be safely applied to living rooms, carpets, bedding, tatami mats, floors, etc., and further, due to the volatilization action and contact action of indoor dust mite repellent ingredients, It is extremely practical because it has an excellent repellent effect on the like.
本発明で用いられる屋内塵性ダニ忌避成分としては、桂皮酸類縁体、ベンズアルデヒド類、オイゲノール類、安息香酸ベンジルエステル類、サリチル酸エステル類、ジャスモン酸エステル類などがあげられるが、天然精油由来で安全性が高く、しかも忌避効果に優れた桂皮酸類縁体が好ましい。
例えば、桂皮酸類縁体が殺ダニ剤としてコナダニ、ヒョウヒダニ、ホコリダニ、ツメダニ等の屋内塵性ダニ類に有効であることは、特開平３−８１２０２号公報や特開平３−１２３７１４号公報などに開示されている。しかしながら、これらの公報に記載の屋内用殺ダニ剤は、有効成分の主に接触作用による殺ダニ効果に基づいていたため、製剤や施用方法に制約があり、実用化には至らなかった。
これに対し本発明では、屋内塵性ダニ類を殺すのではなく、人や患者にダニを近づけないようにする観点から、屋内塵性ダニ忌避成分の屋内塵性ダニ類に対する忌避効果を新たに揮散作用を含めて検討した結果、屋内塵性ダニ忌避成分を不織布製清掃シートに含浸させ、これを処理面に接触させるようになした屋内塵性ダニ忌避用物品が極めて有用であることを見出したものである。
Indoor dust mite repellent components used in the present invention include cinnamic acid analogues, benzaldehydes, eugenols, benzoic acid benzyl esters, salicylic acid esters, jasmonic acid esters, etc. Cinnamic acid analogs having high properties and excellent repellency are preferred.
For example, it is disclosed in JP-A-3-81202, JP-A-3-123714 and the like that cinnamic acid analogs are effective as acaricides for indoor dust mites such as mites, leopard mites, dust mites, and claw mites. Has been. However, the indoor acaricides described in these publications are based on the acaricidal effect mainly due to the contact action of the active ingredients, and thus have limited preparations and application methods and have not been put into practical use.
On the other hand, in the present invention, the indoor dust mite repellent component has a new repellent effect on indoor dust mites from the viewpoint of keeping mites away from people and patients rather than killing indoor dust mites. As a result of examination including volatilization action, it was found that indoor dust mite repellent articles made by impregnating a nonwoven fabric cleaning sheet with an indoor dust mite repellent component and bringing it into contact with the treated surface are extremely useful. It is a thing.
桂皮酸類縁体としては、例えば酢酸シンナミル、蟻酸シンナミル、桂皮酸ベンジル、桂皮酸シンナミル、桂皮酸メチル、桂皮酸エチル、ｐ−メチル桂皮酸メチル、桂皮アルデヒド、α−ヘキシル桂皮アルデヒド、及び桂皮油などから選ばれた１種又は２種以上があげられるが、これらの化合物のなかでは酢酸シンナミル、桂皮酸ベンジル、桂皮アルデヒド、あるいは桂皮油が好ましい。
なお、桂皮酸類縁体は、不織布製清掃シートに含浸させる原液中に０．２〜２０重量％程度配合し、不織布製清掃シートあたり０．００２〜２．０重量％になるように設定するのが適当である。
Cinnamic acid analogs include, for example, cinnamyl acetate, cinnamyl formate, benzyl cinnamate, cinnamyl cinnamate, methyl cinnamate, ethyl cinnamate, methyl p-methyl cinnamate, cinnamic aldehyde, α-hexyl cinnamaldehyde, and cinnamon oil Among these compounds, cinnamyl acetate, benzyl cinnamate, cinnamaldehyde, or cinnamon oil is preferable.
In addition, the cinnamic acid analog is mixed in the stock solution impregnated into the nonwoven fabric cleaning sheet in an amount of about 0.2 to 20% by weight, and is set to 0.002 to 2.0% by weight per nonwoven fabric cleaning sheet. Is appropriate.
本発明では、屋内塵性ダニ忌避成分として、前記桂皮酸類縁体に加え、ベンズアルデヒド類、オイゲノール類や安息香酸ベンジルエステル類を併用するのが好ましい。ヘリオトロピンやアニスアルデヒドのようなベンズアルデヒド類、オイゲノール類や安息香酸ベンジルエステル類についても殺ダニ剤として公知であるが、揮散作用に基づく忌避効果に着目したものはない。
このようなベンズアルデヒド類、オイゲノール類や安息香酸ベンジルエステル類としては、ヘリオトロピン、ｐ−アニスアルデヒド、ｍ−アニスアルデヒド、ペリラアルデヒド、オイゲノール、イソオイゲノール、ジヒドロオイゲノール、オイゲニルアセテート、安息香酸ベンジルなどがあげられるが、これらに限定されない。
ベンズアルデヒド類、オイゲノール類や安息香酸ベンジルエステル類の配合量は、桂皮酸類縁体に対して０．００１〜０．３倍程度が実用的である。
In the present invention, it is preferable to use benzaldehydes, eugenols, and benzoic acid benzyl esters in addition to the cinnamic acid analog as an indoor dusty mite repellent component. Benzaldehydes such as heliotropin and anisaldehyde, eugenols and benzoic acid benzyl esters are also known as acaricides, but none have focused on repellent effects based on volatilization.
Examples of such benzaldehydes, eugenols and benzyl benzoates include heliotropin, p-anisaldehyde, m-anisaldehyde, perilaldehyde, eugenol, isoeugenol, dihydroeugenol, eugenyl acetate, benzyl benzoate, etc. However, it is not limited to these.
The blending amount of benzaldehydes, eugenols and benzoic acid benzyl esters is practically about 0.001 to 0.3 times the cinnamic acid analog.
本発明では、安全性と忌避効果に支障を来たさない限りにおいて、前記桂皮酸類縁体、及びベンズアルデヒド類、オイゲノール類や安息香酸ベンジルエステル類に加え、他のテルペン系の忌避成分、例えばメントール、シトロネロール、テルピネオール、α―ピネン、ゲラニオール、カンファー、リナロール、カラン−３，４−ジオール、あるいはユーカリ、シトロネラ、ニーム、ラベンダー、レモングラス、クローバ、ベルガモット等由来の精油、抽出液、更にサリチル酸エステル類、ジャスモン酸エステル類等を添加してもよい。
また、「緑の香り」と呼ばれる青葉アルコールや青葉アルデヒド配合の香料成分を添加したり、あるいは、殺虫剤、殺菌剤、防黴剤、消臭剤など、他種の有効成分を適宜配合することによって多目的組成物とすることも可能である。
In the present invention, in addition to the cinnamic acid analog and benzaldehydes, eugenols and benzoic acid benzyl esters, other terpene-based repellent components such as menthol, as long as safety and repellent effects are not hindered. , Citronellol, terpineol, α-pinene, geraniol, camphor, linalool, caran-3,4-diol, or eucalyptus, citronella, neem, lavender, lemongrass, clover, bergamot, and other essential oils, extracts, and salicylic acid esters , Jasmonic acid esters and the like may be added.
Also, add a fragrance ingredient containing green leaf alcohol or green leaf aldehyde called "green fragrance", or add other kinds of active ingredients as appropriate, such as insecticides, fungicides, antifungal agents, and deodorants. Can also be used as a multi-purpose composition.
本発明の屋内塵性ダニ忌避用物品は、忌避成分を液状担体に担持させた原液を不織布製清掃シートに含浸させ、このシート中の忌避成分もしくは清掃に伴いこのシートとの接触表面に移行した忌避成分の揮散作用ならびに接触作用により屋内塵性ダニを忌避させるものである。また、本発明の屋内塵性ダニ忌避用物品は、使用感を考慮してドライタイプとし、清掃シートに対する原液の含浸量は、０．５〜１０重量％程度に設定するのが適当である。 The indoor dusty mite repellent article of the present invention impregnates a non-woven cleaning sheet with a stock solution in which the repellent component is supported on a liquid carrier, and moves to the contact surface with this sheet due to the repellent component in the sheet or cleaning. It repels indoor dust mites by the volatilization action and contact action of repellent components. In addition, the indoor dust mite repellent article of the present invention is a dry type considering the feeling of use, and the amount of impregnation of the stock solution to the cleaning sheet is suitably set to about 0.5 to 10% by weight.
ここで、不織布製清掃シートとは、レーヨン、ポリオレフィン、ポリエステル等の繊維集合体を積層もしくは交絡させて得られるシートで、好ましくは、レーヨンを含むポリオレフィン繊維層と、その片面もしくは両面にポリエステル繊維層を交絡させたものがよい。具体的には、繊維径が１０〜２０μの繊維素材を用い、水流交絡法により目付けを４０〜８０ｇ／ｍ2程度に製したシートが使いやすい。
これを用いて畳、フロア、家具等を拭き取ると、繊維集合体の空隙にゴミや埃が捕捉される。このため、シートに含浸される原液の処方としては、忌避成分の他、ゴミや埃の捕捉性の点から界面活性剤、鉱油、シリコーンオイル等を含むのが好ましく、更にダニアレルゲン低減化剤の配合がより好ましい。
市場には、ダニアレルゲンの除去と消臭・除菌を謳ったウェットタイプの清掃シートがいくつか市販されているが、ダニに対する忌避作用は備えていない。これに対し、本発明の屋内塵性ダニ忌避用物品は、忌避成分の揮散作用ならびに接触作用によるダニ忌避を特徴とし、またドライタイプであるため使いやすいというメリットを有する。
Here, the nonwoven fabric cleaning sheet is a sheet obtained by laminating or entangled a fiber assembly of rayon, polyolefin, polyester, etc., preferably a polyolefin fiber layer containing rayon and a polyester fiber layer on one or both sides thereof The thing which entangled is good. Specifically, a sheet made of a fiber material having a fiber diameter of 10 to 20 μm and having a basis weight of about 40 to 80 g / m 2 by a hydroentanglement method is easy to use.
When this is used to wipe tatami mats, floors, furniture, etc., dust and dirt are trapped in the gaps in the fiber assembly. For this reason, the prescription of the stock solution impregnated into the sheet preferably contains a surfactant, mineral oil, silicone oil, etc., in addition to the repellent components, from the viewpoint of dust and dust trapping properties, and further a mite allergen reducing agent. Blending is more preferred.
There are some wet-type cleaning sheets on the market that remove mite allergens and deodorize and disinfect them, but they do not have a repellent action against mites. On the other hand, the indoor dusty mite repellent article of the present invention is characterized by volatilizing action of the repellent component and tick repellent by contact action, and has the merit that it is easy to use because it is a dry type.
原液を調製するに際して、用いられる液状の担体としては、例えば、水、アルコール類（エタノール、イソプロパノール等）、多価アルコール類（ジエチレングリコール、プロピレングリコール、１，３−ブチレングリコール、グリセリン等）、ケトン類（アセトン、メチルエチルケトン、シクロヘキサノン等）、エーテル類（エチルエーテル、ジオキサン、ジエチレングリコールモノブチルエーテル、プロピレングリコールモノメチルエーテル等）、脂肪族炭化水素類（ケロシン、鉱油、灯油類等）、芳香族炭化水素類（キシレン、メチルナフタレン等）、エステル類、酸アミド類、ニトリル類等の溶剤が適当であり、そしてこれらの一種又は二種以上の混合物が使用される。
通常、ゴミや埃の捕捉性の点から鉱油をベースとし、ダニアレルゲン低減化剤の配合を考慮する場合には、エタノールや水を適宜添加すればよい。
In preparing the stock solution, liquid carriers used include, for example, water, alcohols (ethanol, isopropanol, etc.), polyhydric alcohols (diethylene glycol, propylene glycol, 1,3-butylene glycol, glycerin, etc.), ketones (Acetone, methyl ethyl ketone, cyclohexanone, etc.), ethers (ethyl ether, dioxane, diethylene glycol monobutyl ether, propylene glycol monomethyl ether, etc.), aliphatic hydrocarbons (kerosene, mineral oil, kerosene, etc.), aromatic hydrocarbons (xylene) , Methyl naphthalene, etc.), esters, acid amides, nitriles and the like are suitable, and one or a mixture of two or more of these is used.
Usually, from the viewpoint of dust and dust trapping properties, ethanol or water may be added as appropriate when considering the formulation of a mite allergen reducing agent based on mineral oil.
更に、必要に応じて、界面活性剤、分散剤、展着剤、浸透剤、安定剤、ｐＨ調整剤、着色剤等の添加剤を適宜使用してもよく、例えば、環状シリコーンを原液全体量に対して１〜８重量％、好ましくは３〜６重量％程度添加すると、カーペットや寝具等に処理した場合に繊維体の保護に有用である。 Furthermore, if necessary, additives such as surfactants, dispersants, spreading agents, penetrants, stabilizers, pH adjusters, colorants, etc. may be used as appropriate. When added to about 1 to 8% by weight, preferably about 3 to 6% by weight, it is useful for protecting the fibrous body when treated on carpets or bedding.
本発明では、カチオン系界面活性剤、アニオン系界面活性剤あるいはセスキテルペンアルコール等のダニアレルゲン低減化剤を配合するのが好ましい。すなわち、生存ダニを対象区域から遠ざける一方、残った死亡ダニやダニの糞等についてはアレルゲン活性を低減化し、ダニアレルゲンに悩まされない清潔環境を効率的に提供しえるものである。
カチオン系界面活性剤としては、ジ長鎖アルキルジ短鎖アルキル型４級アンモニウム塩（ジステアリルジメチルアンモニウム塩、ジステアリルメチルヒドロキシエチルアンモニウム塩、ジオレイルジメチルアンモニウム塩等）、モノ長鎖アルキルトリ短鎖アルキル型４級アンモニウム塩（ラウリルトリメチルアンモニウム塩、ステアリルジメチルベンジルアンモニウム塩等）、トリ長鎖アルキルモノ短鎖アルキル型４級アンモニウム塩（トリラウリルメチルアンモニウムクロライド、トリステアリルメチルアンモニウムクロライド等）があげられる。なお、適量のカチオン系界面活性剤の配合は、処理繊維体に柔軟性を付与できるというメリットも有する。
一方、アニオン系界面活性剤としては、ラウリルベンゼンスルホン酸塩、ラウリル硫酸塩、ラウリル硫酸トリエタノールアミン、ポリオキシエチレンラウリルエーテル硫酸塩などがあげられ、これらにフェノール系高分子を加えてダニアレルゲン低減化剤を構成してもよい。
ダニアレルゲン低減化剤の配合量は、原液中に０．２〜１０重量％が適当であり、過度の施用は繊維体の感触を損ねる恐れを有するので好ましくない。
In the present invention, it is preferable to incorporate a mite allergen reducing agent such as a cationic surfactant, an anionic surfactant or sesquiterpene alcohol. That is, while the live mites are kept away from the target area, the allergen activity is reduced for the remaining dead mites and mite feces and the like, and a clean environment free from mite allergens can be efficiently provided.
Cationic surfactants include dilong chain alkyldishort chain alkyl quaternary ammonium salts (distearyldimethylammonium salt, distearylmethylhydroxyethylammonium salt, dioleyldimethylammonium salt, etc.), monolong chain alkyltrishort chain Examples include alkyl type quaternary ammonium salts (such as lauryl trimethyl ammonium salt and stearyl dimethyl benzyl ammonium salt) and tri long chain alkyl mono short chain alkyl type quaternary ammonium salts (such as trilauryl methyl ammonium chloride and tristearyl methyl ammonium chloride). . In addition, the mixing | blending of a suitable quantity cationic surfactant also has the merit that a softness | flexibility can be provided to a process fiber body.
On the other hand, examples of anionic surfactants include lauryl benzene sulfonate, lauryl sulfate, lauryl sulfate triethanolamine, and polyoxyethylene lauryl ether sulfate. An agent may be configured.
The blending amount of the mite allergen reducing agent is suitably 0.2 to 10% by weight in the stock solution, and excessive application is not preferable because it may impair the feel of the fibrous body.
こうして得られた本発明の屋内塵性ダニ忌避用物品は、掃除用器具に装着させて居室、カーペットや寝具、畳やフロア等に安心して施用でき、そして人畜に対する安全性が高く、しかもコナダニ、ヒョウヒダニ、ホコリダニ、ツメダニ等などに対して優れた忌避効力を奏するものである。従って、アレルギーの原因となる屋内塵性ダニ類に接することがなくなり、更にダニアレルゲン低減化剤を配合すれば、死亡ダニやダニの糞に起因するアレルゲン活性も抑えることができるので、殺ダニ剤の代替としてその実用性は極めて高い。 The indoor dust mite repellent article of the present invention thus obtained can be applied to a living room, carpet, bedding, tatami mats, floor, etc. with safety by attaching it to a cleaning device, and is highly safe for human livestock. It has excellent repellent effect against leopard mites, dust mites, claw mites and the like. Therefore, it does not come into contact with indoor dust mites that cause allergies, and if a mite allergen reducing agent is further added, allergen activity caused by dead mites and mite feces can be suppressed. As an alternative, its practicality is extremely high.
次に具体的な実施例に基づき、本発明の屋内塵性ダニ忌避用物品について更に詳細に説明する。 Next, based on a specific Example, the indoor dusty mite repellent article of this invention is demonstrated in detail.
屋内塵性忌避成分としての酢酸シンナミル３．０重量％、ｍ−アニスアルデヒド０．０２重量％と、非イオン系界面活性剤（ポリオキシエチレンオレイルエーテル）０．９重量％、シリコーンオイル１．２重量％、カチオン系界面活性剤（ジステアリルジメチルアンモニウム塩）ならびにセスキテルペンアルコールを含有するダニアレルゲン低減化剤１．８重量％とを鉱油に溶解して本発明で用いる原液を調製した。
レーヨンを含むポリオレフィン繊維層の両面にポリエステル繊維集合体を交絡積層させて得られた不織布製清掃シート（目付け：６０ｇ／ｍ2）に、前記原液を当該清掃シートあたり１．５重量％含浸させて、ドライタイプの屋内塵性ダニ忌避用物品を作製した。
この清掃シートをフロア用柄付清掃具の清掃板に巻装して、フローリング床の清掃に供した。その結果、清掃シート中の屋内塵性忌避成分の揮散作用ならびに接触作用、ならびに清掃に伴いこの清掃シートとの接触床表面に移行した忌避成分の揮散作用ならびに接触作用によって、屋内塵性ダニ類が清掃面に寄りつかない効果を付与することができた。また、本発明の屋内塵性ダニ忌避用物品は、清掃中芳香が広がり、ホコリや埃の捕捉性にもすぐれるとともに、死亡ダニやダニの糞によるダニアレルゲン活性も抑えることができるので、極めて実用的であった。
Cinnamyl acetate as an indoor dust repellent component: 3.0% by weight, m-anisaldehyde 0.02% by weight, nonionic surfactant (polyoxyethylene oleyl ether) 0.9% by weight, silicone oil 1.2 A stock solution used in the present invention was prepared by dissolving 1% by weight of a cationic surfactant (distearyldimethylammonium salt) and 1.8% by weight of a mite allergen reducing agent containing sesquiterpene alcohol in mineral oil.
A nonwoven fabric cleaning sheet (weight per unit: 60 g / m 2 ) obtained by entangled and laminated polyester fiber aggregates on both surfaces of a polyolefin fiber layer containing rayon was impregnated with 1.5% by weight of the stock solution per cleaning sheet. A dry type indoor dusty mite repellent article was prepared.
This cleaning sheet was wound around a cleaning plate of a floor-use cleaning tool and used for cleaning the flooring floor. As a result, the volatilization and contact action of the indoor dust repellent component in the cleaning sheet, and the volatilization and contact action of the repellent component transferred to the contact floor surface with this cleaning sheet due to the cleaning, the indoor dust mite It was possible to give the effect of not getting close to the cleaning surface. In addition, the indoor dusty mite repellent article of the present invention spreads aroma during cleaning, has excellent dust and dust trapping properties, and can also suppress mite allergen activity due to dead mites and mite feces, which is extremely It was practical.
屋内塵性忌避成分としての桂皮酸ベンジル６．０重量％、香料３．０重量％と、非イオン系界面活性剤（ポリオキシエチレンアルキルエーテル）２５．０重量％とを鉱油に溶解して本発明で用いる原液を調製した。
ポリエステル繊維集合体を交絡積層させて得られた不織布製清掃シート（目付け：６０ｇ／ｍ2）に、前記原液を当該清掃シートあたり３．０重量％含浸させて、ドライタイプの屋内塵性ダニ忌避用物品を作製した。
この清掃シートをフロア用柄付清掃具の清掃板に巻装して、フローリング床の清掃に供した。その結果、本発明の屋内塵性ダニ忌避用物品は、実施例１と同様、清掃シート中の屋内塵性忌避成分の揮散作用ならびに接触作用、ならびに清掃に伴いこの清掃シートとの接触床表面に移行した忌避成分の揮散作用ならびに接触作用によって、屋内塵性ダニ類が清掃面に寄りつかない効果を付与することができた。また、清掃中芳香が広がり、ホコリや埃の捕捉性にもすぐれ、実用性の高いものであった。
As an indoor dust repellent component, benzyl cinnamate 6.0% by weight, fragrance 3.0% by weight, and nonionic surfactant (polyoxyethylene alkyl ether) 25.0% by weight are dissolved in mineral oil. Stock solutions used in the invention were prepared.
A nonwoven fabric cleaning sheet (weight per unit: 60 g / m 2 ) obtained by entanglement lamination of polyester fiber aggregates is impregnated with 3.0% by weight of the stock solution per cleaning sheet, thereby avoiding dry type indoor dust mites. Articles for manufacture were prepared.
This cleaning sheet was wound around a cleaning plate of a floor-use cleaning tool and used for cleaning the flooring floor. As a result, the indoor dusty mite repellent article of the present invention is the same as in Example 1, the volatilization action and contact action of the indoor dusty repellent component in the cleaning sheet, and the contact floor surface with this cleaning sheet along with cleaning. The volatilization action and contact action of the transferred repellent component provided the effect that indoor dust mites did not approach the cleaning surface. In addition, the fragrance spreads during cleaning, and it has excellent dust and dust trapping properties, making it highly practical.
試験の結果、本発明の屋内塵性ダニ忌避用物品は、忌避効果が高く、その結果としてダニアレルゲン活性の抑制作用の点でも効果的であった。なお、屋内塵性ダニ忌避成分としては、桂皮酸類縁体や、これとベンズアルデヒド類及び／又はオイゲノール類との併用がより好ましかった。更に、ダニアレルゲン低減化剤の配合は、死亡ダニやダニの糞によるダニアレルゲン活性を抑えるほか、忌避効果の向上の点でも有用であることが認められた。
これに対し、比較例１の如く、従来の殺ダニ剤を用いると死亡ダニとして残るため、ダニアレルゲン活性の低減に繋がらなかった。また、ダニアレルゲン低減化剤として提案されたセスキテルペンアルコール（比較例２）は忌避効果が低く、ダニアレルゲン低減化剤の施用のみではダニアレルゲン問題を総合的に解決するのは困難と考えられた。
As a result of the test, the indoor dusty mite repellent article of the present invention has a high repellent effect, and as a result, was effective in terms of the action of suppressing mite allergen activity. As the indoor dust mite repellent component, cinnamic acid analogs and combinations thereof with benzaldehydes and / or eugenols were more preferred. Furthermore, it was confirmed that the addition of the mite allergen reducing agent is useful in terms of suppressing the mite allergen activity caused by dead mites and mite feces, and improving the repellent effect.
On the other hand, when the conventional acaricide was used as in Comparative Example 1, it remained as a dead mite, and thus did not lead to a reduction in mite allergen activity. In addition, sesquiterpene alcohol (Comparative Example 2) proposed as a mite allergen reducing agent has a low repellent effect, and it was considered difficult to comprehensively solve the mite allergen problem only by applying the mite allergen reducing agent. .
本発明の屋内塵性ダニ忌避用物品は、有効成分を選択して、屋内塵性ダニ類だけでなく、ゴキブリ等の屋内害虫にも適用できる可能性がある。
The indoor dust mite repellent article of the present invention may be applicable not only to indoor dust mites but also to indoor pests such as cockroaches by selecting an active ingredient.
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