CN103766339B - The composition that contains trans-cinnamic aldehyde - Google Patents

The composition that contains trans-cinnamic aldehyde Download PDF

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Publication number
CN103766339B
CN103766339B CN201310567966.9A CN201310567966A CN103766339B CN 103766339 B CN103766339 B CN 103766339B CN 201310567966 A CN201310567966 A CN 201310567966A CN 103766339 B CN103766339 B CN 103766339B
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composition
cinnamic aldehyde
quality percentage
trans
percentage composition
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CN103766339A (en
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宋瑜丽
于录
唐旭东
申凤鸽
许剑怡
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Shenzhen songzhile Biotechnology Co., Ltd
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SHENZHEN SONGLE BIOTECHNOLOGY CO Ltd
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Abstract

A kind of miticide composition, it contains trans-cinnamic aldehyde, surfactant, solvent, and wherein the quality percentage composition of trans-cinnamic aldehyde is 0.0084%-0.268%, and the quality percentage composition of surfactant is 0.5%-2%. This miticide composition can effectively kill the acarid in environment, reduces the harm that human body is caused; Or this miticide composition can be used as food preservative use, can be effectively anticorrosion. The present invention also provides the skin care compositions and the oral care composition that contain trans-cinnamic aldehyde.

Description

The composition that contains trans-cinnamic aldehyde
Technical field
The present invention relates to a kind of miticide composition that contains trans-cinnamic aldehyde, skin care compositions,And oral care composition.
Background technology
Acarid belongs to arthropod, is the miniature insect that a kind of naked eyes are difficult for seeing, kind veryMany, find that at present the acarid of living has more than 40 to plant in room. Modal comprise dirt mite,Flour mite, wriggle mite, itch mite etc. are all important pests common in room, and the health of human body is producedRaw greatly harm.
Dirt mite is to occupy indoor distribution the most extensive, and they are distributed in carpet, curtain, sofa, hairSuede toy, bed clothes, cushion, mattress and pillow etc. are located to grow, with people's sweat, secretion,Exuviae bits are food, and reproduction speed is exceedingly fast. Corpse, secretion and the excreta of dirt mite are allBe can be pathogenic anaphylactogen. Dirt mite can, along with people's activity, be folded quilt as made the bed, sweep and defendThe dust of kicking up in life etc. flies in the air, is inhaled in lung. At this moment, allergic constitution person willProduce the changes such as allergic asthma, bronchitis, ephritis, allergic rhinitis and allergic dermatitisState reactive disorder. Flour mite mainly resides in food, human body use after can cause diarrhoea,Become thin and the illness such as anaemia. The mite main parasitic of wriggling in people's hair follicle and sebaceous glands, as nose,The places such as ear, scalp, shirtfront, back, duct. The existence of mite of wriggling can be stopped up skin pore,And destroy pilosebaceous follicle, cause the skin such as pore is thick, pachylosis, acne, acneProblem, heavy develop into chronic skin disease, as acne rosacea. Itch mite parasitizes people and lactationThe skin surface of animal, its activity, swallowing all can chafe with excreta, and night is moreAcutely, thus patient scratch skin and secondary bacterium infect, occur running sore, folliculitis or furuncleSwollen.
Summary of the invention
In view of this, be necessary to provide a kind of composition that can kill mite.
A kind of miticide composition, it contains trans-cinnamic aldehyde, surfactant, solvent, itsThe quality percentage composition of middle trans-cinnamic aldehyde is 0.0084%-0.268%, the matter of surfactantAmount percentage composition is 0.5%-2%.
This miticide composition can effectively kill the acarid in environment, reduces the danger that human body is causedEvil; Or this miticide composition can be used as food preservative use, can be effectively anticorrosion.
A kind of skin care compositions, it contains trans-cinnamic aldehyde, salicylic acid, curcumin, solvent,In said composition, the quality percentage composition of trans-cinnamic aldehyde is 0.0084%-0.268%, salicylic acidQuality percentage composition be 0.5%-3%, the quality percentage composition of curcumin is 0.1%-0.2%.
This skin care compositions can be used for the acne that mite infection causes, the treatment of whelk, effectFruit significantly.
A kind of oral care composition, it contains trans-cinnamic aldehyde, polyvinyl acetate, moltenAgent, wherein in said composition, the concentration of trans-cinnamic aldehyde is 0.008-0.256mg/ml, poly-vinegarThe quality percentage composition of vinyl acetate is 2%-10%.
This oral care composition can effectively keep the pure and fresh of oral cavity and promote healing of canker soreClose.
Detailed description of the invention
Trans-cinnamic aldehyde is to have strong canellaceous weak yellow liquid, and they can be by original inhabitantsCinnamon bark or other cinnamon extract acquisition or chemical synthesis makes. Trans-cinnamic aldehydeMolecular formula is C9H8O, molecular weight is 132.16g/mol, and density is 1.05g/ml, and fusing point is-7.5 DEG C, boiling point is 248 DEG C, water insoluble, is dissolved in ethanol and ether etc. Trans Chinese cassia treeThe structural formula of aldehyde is:
Trans-cinnamic aldehyde has antibacterial activity, antibiont film activity, and acaricidal activity, kills mosquito and livesProperty, antipathogen activity, anti-inflammatory activity, anti-red fire ant activity, anti-hyperuricemia is livedProperty etc.
A kind of miticide composition, it is mainly in order to kill the acarid in environment or to prevent as foodRotten agent is used. This miticide composition contains trans-cinnamic aldehyde, surfactant (poly-mountain multitude's ester80), solvent (distilled water). In said composition, the quality percentage composition of trans-cinnamic aldehyde is0.0084%-0.268%, the quality percentage composition of surfactant is 0.5%-2%.
In this miticide composition, also alternative is added glycerine, in order to increase the thickness of compositionDegree. The quality percentage composition of this glycerine is 5%-10%.
In this miticide composition, also alternative is added jamaicin, in order to further enhancing combinationThe antibiotic and sterilizing effect of thing. The quality percentage composition of this jamaicin is 0.0011%-0.003%.
In addition, in this miticide composition, also alternative is added in salicylic acid and curcuminAt least one. Wherein, salicylic acid plays effect of anti-inflammatory, and salicylic quality percentage containsAmount is 0.5%-3%; Curcumin plays oxidation resistant effect, the quality percentage composition of curcuminFor 0.001-0.002%.
Below by embodiment, the present invention is specifically described.
Embodiment 1-3
Join three kinds of miticide compositions of the recipe configuration embodiment 1-3 of form below. Be speciallyFollowing each component is uniformly mixed.
Table one
The miticide composition that embodiment 1-3 makes can effectively kill the acarid in environment, reducesThe harm (as allergic reaction) that human body is caused.
A kind of skin care compositions, it is mainly used in, and Propiobacterium infects or acarid is bred and causesThe treatment of all kinds of whelks. This skin care compositions contains trans-cinnamic aldehyde, salicylic acid, gingerFlavine, solvent (distilled water). In said composition, the quality percentage composition of trans-cinnamic aldehyde is0.0084%-0.268%, salicylic quality percentage composition is 0.5%-3%, the matter of curcuminAmount percentage composition is 0.1%-0.2%.
In this skin care compositions, also alternative is added glycerine, in order to increase the thickness of compositionDegree. The quality percentage composition of this glycerine is 5%-10%.
In this miticide composition, also alternative is added jamaicin, in order to further enhancing combinationThe antibiotic and sterilizing effect of thing. The quality percentage composition of this jamaicin is 0.11%-0.3%.
In addition, in this miticide composition, also alternative is added carbomer, Cobastab, secondAt least one in alcohol, reed fragrant plant glue, hyaluronic acid and triethanolamine. Wherein, carbomerPlay effect of gel, the quality percentage composition of carbomer is less than or equal to 2% for being greater than 0;The quality percentage composition of ethanol is 2%-8%; Reed fragrant plant glue plays moisture-keeping function, and plays improvementThe rheological behavior of composition, the quality percentage composition of reed fragrant plant glue is 0.5%-5%; Hyaluronic acidPlay effect of nourishes rough skin with Cobastab, wherein hyaluronic quality percentage composition is0.5%-1%, the quality percentage composition of Cobastab is less than or equal to 0.002% for being greater than 0; ThreeMonoethanolamine plays effect of pH adjusting agent, in order to regulate the pH to 6-8 of composition.
Below by embodiment, the present invention is specifically described.
Embodiment 4-6
Join three kinds of skin care compositions of the recipe configuration embodiment 4-6 of form below. Be speciallyAfter first salicylic acid, jamaicin, curcumin proportionally being dissolved with distilled water, add again cardRipple nurse, to 6-8, finally adds trans-cinnamic aldehyde with triethanolamine fine setting pH value of solution,Formation gel stirs.
Table two
Project Embodiment 4 Embodiment 5 Embodiment 6
Trans-cinnamic aldehyde 0.0084% 0.168% 0.268%
Salicylic acid 0.5% 2% 3%
Jamaicin 0.11% 0.22% 0.3%
Curcumin 0.1% 0.15% 0.2%
Carbomer 1% 1.5% 2.0%
Triethanolamine In right amount In right amount In right amount
Distilled water Surplus Surplus Surplus
The skin care compositions that embodiment 4-6 makes can be used for acne, the green grass or young crops that mite infection causesThe treatment of spring acne, effect is remarkable.
A kind of oral care composition, it is mainly in order to the pure and fresh of effective maintenance oral cavity and promotionThe healing of canker sore. This oral care composition contains trans-cinnamic aldehyde, polyvinyl acetateEster (degree of polymerization is 200~700), solvent (distilled water). Trans-cinnamic aldehyde in said compositionConcentration be that quality percentage composition is 0.0084%-0.268%, the quality hundred of polyvinyl acetateDividing content is 2%-10%.
That this trans-cinnamic aldehyde plays is antibacterial, promote the effect of canker sore healing.
Polyvinyl acetate, as polymer, is the basic colloid of composition, plays solid and doesWith.
In this skin care compositions, also alternative is added xylitol, dibutyl hydroxy toluene(BHT), at least one in flavorant. Wherein, xylitol is as the seasoning of compositionAgent, its quality percentage composition is 8%-15%; Dibutyl hydroxy toluene (BHT) is as groupThe antioxidant of compound, its quality percentage composition is less than or equal to 0.01% for being greater than 0; EdibleThe quality percentage composition of spices is 0.001%-0.01%.
Below by embodiment, the present invention is specifically described.
Embodiment 7-9
Join three kinds of oral care compositions of the recipe configuration embodiment 7-9 of form below. ToolBody is for to be uniformly mixed following each component.
Table three
Three kinds of oral care compositions of embodiment 7-9 can effectively keep the pure and fresh and short of oral cavityThe healing of snout cavity ulcer.
In addition, those skilled in the art also can be in the claims in the present invention scope of disclosure and essenceIn god, make various amendments, interpolation and replacement in other form and details. Certainly, these are complied withThe variations such as various amendments, interpolation and the replacement of making according to spirit of the present invention, all should be included in thisWithin inventing scope required for protection.

Claims (2)

1. a miticide composition, is characterized in that: this miticide composition by trans-cinnamic aldehyde,Surfactant, distilled water, glycerine, jamaicin, salicylic acid and curcumin composition, this tableSurface-active agent is polyoxyethylene sorbitan monoleate, and wherein the quality percentage composition of trans-cinnamic aldehyde is0.0084%-0.268%, the quality percentage composition of surfactant is 0.5%-1.2%.
2. miticide composition as claimed in claim 1, is characterized in that: the matter of this glycerineAmount percentage composition is 5%-10%, and the quality percentage composition of jamaicin is 0.0011%-0.003%,Salicylic quality percentage composition is 0.5%-3%, and the quality percentage composition of curcumin is0.001-0.002%。
CN201310567966.9A 2013-11-13 2013-11-13 The composition that contains trans-cinnamic aldehyde Active CN103766339B (en)

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CN108478478A (en) * 2018-03-09 2018-09-04 佛山市三水区嘉华化学研究院(普通合伙) A kind of hydrogel microcapsule and its application in preparing cosmetics
CN109221207A (en) * 2018-09-04 2019-01-18 徐州光环新能源科技有限公司 A kind of indoor flower pesticide and preparation method thereof
BR112022015597A2 (en) * 2020-02-21 2022-09-27 Firmenich & Cie ANTIMICROBIAL COMPOSITIONS
CN113491685B (en) * 2021-09-09 2021-12-10 广东工业大学 Composition for inhibiting macrophage activation and application thereof in preparation of anti-inflammatory product

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JP2775488B2 (en) * 1989-10-06 1998-07-16 大日本除蟲菊株式会社 How to control indoor dust mites
US5536501A (en) * 1994-12-30 1996-07-16 Proguard, Inc. Use of flavenoid aldehydes as insecticides and for killing arachnids
DE69929233T2 (en) * 1998-10-23 2006-09-07 The Procter & Gamble Company, Cincinnati COMPOSITION AND METHOD OF TEXTILE CARE
KR100350391B1 (en) * 2000-12-23 2002-08-28 주식회사 내츄로바이오텍 Composition contained acaricidal activity derived from plant
JP4641773B2 (en) * 2004-09-27 2011-03-02 大日本除蟲菊株式会社 Indoor dust mite repellent
JP5004468B2 (en) * 2005-02-15 2012-08-22 大日本除蟲菊株式会社 Indoor dust mite repellent article
CN101589729B (en) * 2009-07-03 2013-06-12 中国热带农业科学院环境与植物保护研究所 Cinnamomum zeylanicum extract and use thereof in acaricide
CN102084867A (en) * 2011-03-03 2011-06-08 王超 Germicidal disinfectant

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Address after: 518057 research building C411, Research Institute of Tsinghua University, Shenzhen, Nanshan District, Guangdong

Patentee after: Shenzhen songzhile Biotechnology Co., Ltd

Address before: 518055 Nanshan District science and Technology Park, Guangdong, South seven road, Shenzhen Institute of Tsinghua University, Shenzhen, C411

Patentee before: SHENZHEN SONGLE BIOTECHNOLOGY Co.,Ltd.