JP4994533B2 - コネキシンに対するアンチセンスヌクレオチドを含む配合物 - Google Patents

コネキシンに対するアンチセンスヌクレオチドを含む配合物 Download PDF

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JP4994533B2
JP4994533B2 JP2000595711A JP2000595711A JP4994533B2 JP 4994533 B2 JP4994533 B2 JP 4994533B2 JP 2000595711 A JP2000595711 A JP 2000595711A JP 2000595711 A JP2000595711 A JP 2000595711A JP 4994533 B2 JP4994533 B2 JP 4994533B2
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connexin
antisense
odn
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injury
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JP2002535377A (ja
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ベツカー,デイビツド・ローレンス
グリーン,コリン・リチヤード
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デイビツド・エル・ベツカー
コリン・アール・グリーン
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    • C07ORGANIC CHEMISTRY
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    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/12Keratolytics, e.g. wart or anti-corn preparations
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    • A61P17/16Emollients or protectives, e.g. against radiation
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
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    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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    • C12N2310/00Structure or type of the nucleic acid
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    • C12N2320/00Applications; Uses
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JP2000595711A 1999-01-27 2000-01-27 コネキシンに対するアンチセンスヌクレオチドを含む配合物 Expired - Lifetime JP4994533B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
NZ333928 1999-01-27
NZ33392899 1999-01-27
NZ500190 1999-10-07
NZ50019099 1999-10-07
PCT/GB2000/000238 WO2000044409A1 (en) 1999-01-27 2000-01-27 Formulations comprising antisense nucleotides to connexins

Related Child Applications (1)

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JP2011179832A Division JP2012041342A (ja) 1999-01-27 2011-08-19 コネキシンに対するアンチセンスヌクレオチドを含む配合物

Publications (2)

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JP2002535377A JP2002535377A (ja) 2002-10-22
JP4994533B2 true JP4994533B2 (ja) 2012-08-08

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JP2000595711A Expired - Lifetime JP4994533B2 (ja) 1999-01-27 2000-01-27 コネキシンに対するアンチセンスヌクレオチドを含む配合物
JP2011179832A Pending JP2012041342A (ja) 1999-01-27 2011-08-19 コネキシンに対するアンチセンスヌクレオチドを含む配合物
JP2013015172A Expired - Lifetime JP5736397B2 (ja) 1999-01-27 2013-01-30 コネキシンに対するアンチセンスヌクレオチドを含む配合物
JP2013015171A Expired - Lifetime JP5705890B2 (ja) 1999-01-27 2013-01-30 コネキシンに対するアンチセンスヌクレオチドを含む配合物

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JP2011179832A Pending JP2012041342A (ja) 1999-01-27 2011-08-19 コネキシンに対するアンチセンスヌクレオチドを含む配合物
JP2013015172A Expired - Lifetime JP5736397B2 (ja) 1999-01-27 2013-01-30 コネキシンに対するアンチセンスヌクレオチドを含む配合物
JP2013015171A Expired - Lifetime JP5705890B2 (ja) 1999-01-27 2013-01-30 コネキシンに対するアンチセンスヌクレオチドを含む配合物

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US (11) US7098190B1 (https=)
EP (3) EP2314321B1 (https=)
JP (4) JP4994533B2 (https=)
AT (2) ATE533515T1 (https=)
AU (1) AU776512B2 (https=)
CA (2) CA2730386C (https=)
CY (2) CY1112557T1 (https=)
DE (1) DE60021700T2 (https=)
DK (3) DK1621212T3 (https=)
ES (3) ES2377749T3 (https=)
NZ (1) NZ513154A (https=)
PT (3) PT1621212E (https=)
WO (1) WO2000044409A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012041342A (ja) * 1999-01-27 2012-03-01 Becker David L コネキシンに対するアンチセンスヌクレオチドを含む配合物

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