JP4992025B2 - 変異体il−10 - Google Patents

変異体il−10 Download PDF

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Publication number
JP4992025B2
JP4992025B2 JP2008514767A JP2008514767A JP4992025B2 JP 4992025 B2 JP4992025 B2 JP 4992025B2 JP 2008514767 A JP2008514767 A JP 2008514767A JP 2008514767 A JP2008514767 A JP 2008514767A JP 4992025 B2 JP4992025 B2 JP 4992025B2
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aav
vector
sequence
gene
polypeptide
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Japanese (ja)
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JP2008541759A (ja
JP2008541759A5 (https=
Inventor
イョルグ エム. ソマー,
レイモンド エー. チャベス,
カーク ダブリュー. ジョンソン,
リンダ メイ ロスブルーム ワトキンス,
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University of Colorado System
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/2066IL-10
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    • CCHEMISTRY; METALLURGY
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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
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  • Neurology (AREA)
  • Biomedical Technology (AREA)
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  • Diabetes (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
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  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
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JP2008514767A 2005-05-31 2006-05-26 変異体il−10 Active JP4992025B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68627205P 2005-05-31 2005-05-31
US60/686,272 2005-05-31
PCT/US2006/020863 WO2006130580A2 (en) 2005-05-31 2006-05-26 Mutant il-10

Related Child Applications (1)

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JP2012019756A Division JP2012130344A (ja) 2005-05-31 2012-02-01 変異体il−10

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JP2008541759A JP2008541759A (ja) 2008-11-27
JP2008541759A5 JP2008541759A5 (https=) 2009-05-07
JP4992025B2 true JP4992025B2 (ja) 2012-08-08

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JP2008514767A Active JP4992025B2 (ja) 2005-05-31 2006-05-26 変異体il−10
JP2012019756A Withdrawn JP2012130344A (ja) 2005-05-31 2012-02-01 変異体il−10

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US (1) US7749490B2 (https=)
EP (1) EP1891103B1 (https=)
JP (2) JP4992025B2 (https=)
AT (1) ATE452908T1 (https=)
CA (1) CA2609543C (https=)
DE (1) DE602006011311D1 (https=)
WO (1) WO2006130580A2 (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7052686B2 (en) 2000-09-29 2006-05-30 Schering Corporation Pegylated interleukin-10
US7261882B2 (en) * 2003-06-23 2007-08-28 Reagents Of The University Of Colorado Methods for treating neuropathic pain by administering IL-10 polypeptides
LT2816118T (lt) * 2005-05-31 2018-12-10 The Regents Of The University Of Colorado, A Body Corporate Genų pristatymo būdai
CA2664304C (en) * 2006-09-28 2017-08-22 Schering Corporation Use of pegylated il-10 to treat cancer
EP3348281B1 (en) 2008-12-17 2023-07-05 Merck Sharp & Dohme Corp. Mono- and di-peg il-10 production; and uses
CN104136457A (zh) 2011-11-08 2014-11-05 Umc乌德勒支控股有限公司 包括白细胞介素10和白细胞介素4的融合蛋白
WO2013103966A1 (en) * 2012-01-06 2013-07-11 The Regents Of The University Of Colorado, A Body Corporate Methods for the treatment of multiple sclerosis and other demyelinating disorders
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