CA2609543C - Mutant il-10 - Google Patents

Mutant il-10 Download PDF

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Publication number
CA2609543C
CA2609543C CA2609543A CA2609543A CA2609543C CA 2609543 C CA2609543 C CA 2609543C CA 2609543 A CA2609543 A CA 2609543A CA 2609543 A CA2609543 A CA 2609543A CA 2609543 C CA2609543 C CA 2609543C
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Canada
Prior art keywords
aav
vector
gene
mutant
vectors
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CA2609543A
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English (en)
French (fr)
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CA2609543A1 (en
Inventor
Jurg M. Sommer
Raymond A. Chavez
Kirk W. Johnson
Linda May Rothblum Watkins
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University of Colorado Boulder
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University of Colorado Boulder
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2066—IL-10
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    • C—CHEMISTRY; METALLURGY
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    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
CA2609543A 2005-05-31 2006-05-26 Mutant il-10 Active CA2609543C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68627205P 2005-05-31 2005-05-31
US60/686,272 2005-05-31
PCT/US2006/020863 WO2006130580A2 (en) 2005-05-31 2006-05-26 Mutant il-10

Publications (2)

Publication Number Publication Date
CA2609543A1 CA2609543A1 (en) 2006-12-07
CA2609543C true CA2609543C (en) 2015-03-24

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2609543A Active CA2609543C (en) 2005-05-31 2006-05-26 Mutant il-10

Country Status (7)

Country Link
US (1) US7749490B2 (https=)
EP (1) EP1891103B1 (https=)
JP (2) JP4992025B2 (https=)
AT (1) ATE452908T1 (https=)
CA (1) CA2609543C (https=)
DE (1) DE602006011311D1 (https=)
WO (1) WO2006130580A2 (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7052686B2 (en) 2000-09-29 2006-05-30 Schering Corporation Pegylated interleukin-10
US7261882B2 (en) * 2003-06-23 2007-08-28 Reagents Of The University Of Colorado Methods for treating neuropathic pain by administering IL-10 polypeptides
LT2816118T (lt) * 2005-05-31 2018-12-10 The Regents Of The University Of Colorado, A Body Corporate Genų pristatymo būdai
CA2664304C (en) * 2006-09-28 2017-08-22 Schering Corporation Use of pegylated il-10 to treat cancer
EP3348281B1 (en) 2008-12-17 2023-07-05 Merck Sharp & Dohme Corp. Mono- and di-peg il-10 production; and uses
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WO2013103966A1 (en) * 2012-01-06 2013-07-11 The Regents Of The University Of Colorado, A Body Corporate Methods for the treatment of multiple sclerosis and other demyelinating disorders
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