ATE452908T1 - Il-10 mutante - Google Patents
Il-10 mutanteInfo
- Publication number
- ATE452908T1 ATE452908T1 AT06771553T AT06771553T ATE452908T1 AT E452908 T1 ATE452908 T1 AT E452908T1 AT 06771553 T AT06771553 T AT 06771553T AT 06771553 T AT06771553 T AT 06771553T AT E452908 T1 ATE452908 T1 AT E452908T1
- Authority
- AT
- Austria
- Prior art keywords
- retain
- mutant
- hemoatopoeitic
- polypeptides
- wild
- Prior art date
Links
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000028709 inflammatory response Effects 0.000 abstract 1
- 208000004296 neuralgia Diseases 0.000 abstract 1
- 208000021722 neuropathic pain Diseases 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
Classifications
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2066—IL-10
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
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- C07K14/5428—IL-10
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
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- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pain & Pain Management (AREA)
- Tropical Medicine & Parasitology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68627205P | 2005-05-31 | 2005-05-31 | |
| PCT/US2006/020863 WO2006130580A2 (en) | 2005-05-31 | 2006-05-26 | Mutant il-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE452908T1 true ATE452908T1 (de) | 2010-01-15 |
Family
ID=37482214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06771553T ATE452908T1 (de) | 2005-05-31 | 2006-05-26 | Il-10 mutante |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7749490B2 (https=) |
| EP (1) | EP1891103B1 (https=) |
| JP (2) | JP4992025B2 (https=) |
| AT (1) | ATE452908T1 (https=) |
| CA (1) | CA2609543C (https=) |
| DE (1) | DE602006011311D1 (https=) |
| WO (1) | WO2006130580A2 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2295450B1 (en) | 2000-09-29 | 2015-01-28 | Merck Sharp & Dohme Corp. | Pegylated interleukin-10 |
| US7261882B2 (en) * | 2003-06-23 | 2007-08-28 | Reagents Of The University Of Colorado | Methods for treating neuropathic pain by administering IL-10 polypeptides |
| HUE041875T2 (hu) * | 2005-05-31 | 2019-06-28 | Univ Colorado Regents | Eljárás génbejuttatásra |
| EP2066336B1 (en) | 2006-09-28 | 2012-09-19 | Merck Sharp & Dohme Corp. | Use of pegylated il-10 to treat cancer |
| ES2655364T3 (es) | 2008-12-17 | 2018-02-19 | Merck Sharp & Dohme Corp. | Producción de IL-10 mono- y dipegilada y sus usos |
| WO2013070076A1 (en) | 2011-11-08 | 2013-05-16 | Umc Utrecht Holding B.V. | Fusion protein comprising an interleukin 4 and interleukin |
| US20150044281A1 (en) * | 2012-01-06 | 2015-02-12 | The Regents Of The University Of Colorado, A Body Corporate | Methods for the treatment of multiple sclerosis and other demyelinating disorders |
| MX2015014438A (es) | 2013-04-18 | 2016-05-18 | Armo Biosciences Inc | Metodos de uso de interleucina-10 para tratar enfermedades y trastornos. |
| EP2989240A4 (en) * | 2013-04-24 | 2016-10-19 | Armo Biosciences Inc | INTERLEUKIN-10 COMPOSITIONS AND USES THEREOF |
| EP3010527B1 (en) | 2013-06-17 | 2018-08-08 | Armo Biosciences, Inc. | Method for assessing protein identity and stability |
| PL3369435T3 (pl) * | 2013-07-18 | 2020-04-30 | Xalud Therapeutics, Inc. | Kompozycja do leczenia choroby zapalnej stawów |
| CN105658232A (zh) | 2013-08-30 | 2016-06-08 | 阿尔莫生物科技股份有限公司 | 使用白细胞介素-10治疗疾病和病症的方法 |
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| US6428985B1 (en) | 1998-12-02 | 2002-08-06 | The Regents Of The University Of Michigan | Immunosuppressive structural definition of IL-10 |
| WO2001058950A1 (en) * | 2000-02-11 | 2001-08-16 | Maxygen Aps | Improved interleukin 10 |
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| US20090035256A1 (en) | 2009-02-05 |
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| HK1114107A1 (en) | 2008-10-24 |
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| EP1891103A2 (en) | 2008-02-27 |
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