JP4990886B2 - 改良ポリメラーゼ - Google Patents

改良ポリメラーゼ Download PDF

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Publication number
JP4990886B2
JP4990886B2 JP2008510637A JP2008510637A JP4990886B2 JP 4990886 B2 JP4990886 B2 JP 4990886B2 JP 2008510637 A JP2008510637 A JP 2008510637A JP 2008510637 A JP2008510637 A JP 2008510637A JP 4990886 B2 JP4990886 B2 JP 4990886B2
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polymerase
dna
nucleotide
amino acid
nucleotides
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Japanese (ja)
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JP2008539750A5 (enExample
JP2008539750A (ja
Inventor
トバイアス, ウィリアム, バー オスト,
ジオフレー, ポール スミス,
シャンカー バラスブラマニアン,
ロベルト リガッティー,
ラクエル, マリア サンチェス,
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ソレックサ リミテッド
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)
    • C12N9/1252DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07Nucleotidyltransferases (2.7.7)
    • C12Y207/07007DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2008510637A 2005-05-10 2006-05-10 改良ポリメラーゼ Expired - Fee Related JP4990886B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0509508A GB0509508D0 (en) 2005-05-10 2005-05-10 Improved polymerases
GB0509508.8 2005-05-10
US75799706P 2006-01-11 2006-01-11
US60/757,997 2006-01-11
PCT/GB2006/001700 WO2006120433A1 (en) 2005-05-10 2006-05-10 Improved polymerases

Publications (3)

Publication Number Publication Date
JP2008539750A JP2008539750A (ja) 2008-11-20
JP2008539750A5 JP2008539750A5 (enExample) 2009-06-25
JP4990886B2 true JP4990886B2 (ja) 2012-08-01

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US (4) US8623628B2 (enExample)
EP (1) EP1888743B1 (enExample)
JP (1) JP4990886B2 (enExample)
WO (1) WO2006120433A1 (enExample)

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