PL3161154T3 - Zmodyfikowane polimerazy do ulepszonego włączania analogów nukleotydów - Google Patents

Zmodyfikowane polimerazy do ulepszonego włączania analogów nukleotydów

Info

Publication number
PL3161154T3
PL3161154T3 PL15739706T PL15739706T PL3161154T3 PL 3161154 T3 PL3161154 T3 PL 3161154T3 PL 15739706 T PL15739706 T PL 15739706T PL 15739706 T PL15739706 T PL 15739706T PL 3161154 T3 PL3161154 T3 PL 3161154T3
Authority
PL
Poland
Prior art keywords
nucleotide analogs
modified polymerases
improved engagement
engagement
improved
Prior art date
Application number
PL15739706T
Other languages
English (en)
Inventor
Cheng-Yao Chen
Erin BOMATI
Molly He
Original Assignee
Illumina, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina, Inc. filed Critical Illumina, Inc.
Publication of PL3161154T3 publication Critical patent/PL3161154T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07007—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL15739706T 2014-06-27 2015-06-25 Zmodyfikowane polimerazy do ulepszonego włączania analogów nukleotydów PL3161154T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462018470P 2014-06-27 2014-06-27
PCT/US2015/037785 WO2015200693A1 (en) 2014-06-27 2015-06-25 Modified polymerases for improved incorporation of nucleotide analogues
EP15739706.8A EP3161154B1 (en) 2014-06-27 2015-06-25 Modified polymerases for improved incorporation of nucleotide analogues

Publications (1)

Publication Number Publication Date
PL3161154T3 true PL3161154T3 (pl) 2020-10-19

Family

ID=53716556

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15739706T PL3161154T3 (pl) 2014-06-27 2015-06-25 Zmodyfikowane polimerazy do ulepszonego włączania analogów nukleotydów

Country Status (10)

Country Link
US (3) US9765309B2 (pl)
EP (2) EP3702471B1 (pl)
JP (3) JP6737710B2 (pl)
CN (1) CN106536728A (pl)
AU (2) AU2015279794B2 (pl)
DK (1) DK3161154T3 (pl)
ES (1) ES2788949T3 (pl)
PL (1) PL3161154T3 (pl)
PT (1) PT3161154T (pl)
WO (1) WO2015200693A1 (pl)

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US11591629B2 (en) * 2019-12-23 2023-02-28 Cheng-Yao Chen Method and kit for template-independent nucleic acid synthesis
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TWI869710B (zh) * 2021-09-29 2025-01-11 呈堯 陳 用於無模板ｒｎａ合成的核酸聚合酶變體、試劑套組及方法
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WO2024155578A1 (en) * 2023-01-16 2024-07-25 The Regents Of The University Of California Engineered polymerase for threose nucleic acid synthesis
CN116286720A (zh) * 2023-03-29 2023-06-23 赛纳生物科技(北京)有限公司 一种dna聚合酶
WO2025260380A1 (zh) * 2024-06-21 2025-12-26 华大工程生物学长荡湖研究所 重组型kod聚合酶

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Also Published As

Publication number Publication date
EP3702471C0 (en) 2025-12-24
ES2788949T3 (es) 2020-10-23
JP2020127415A (ja) 2020-08-27
CA2951416A1 (en) 2015-12-30
EP3702471A1 (en) 2020-09-02
DK3161154T3 (da) 2020-06-15
JP2017518750A (ja) 2017-07-13
AU2015279794B2 (en) 2021-09-30
CN106536728A (zh) 2017-03-22
US12110514B2 (en) 2024-10-08
US20170355970A1 (en) 2017-12-14
AU2021290289B2 (en) 2024-02-15
AU2021290289A1 (en) 2022-01-27
EP3702471B1 (en) 2025-12-24
JP6737710B2 (ja) 2020-08-12
PT3161154T (pt) 2020-06-08
US10870836B2 (en) 2020-12-22
WO2015200693A1 (en) 2015-12-30
HK1231517A1 (en) 2017-12-22
US9765309B2 (en) 2017-09-19
US20210246435A1 (en) 2021-08-12
EP3161154A1 (en) 2017-05-03
US20150376582A1 (en) 2015-12-31
AU2015279794A1 (en) 2016-12-22
EP3161154B1 (en) 2020-04-15
JP2022033882A (ja) 2022-03-02

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