JP4972549B2 - Ｔ細胞レセプターを改善する方法 - Google Patents

Ｔ細胞レセプターを改善する方法 Download PDF

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JP4972549B2
JP4972549B2 JP2007517396A JP2007517396A JP4972549B2 JP 4972549 B2 JP4972549 B2 JP 4972549B2 JP 2007517396 A JP2007517396 A JP 2007517396A JP 2007517396 A JP2007517396 A JP 2007517396A JP 4972549 B2 JP4972549 B2 JP 4972549B2
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tcr
sequence
affinity
tcrs
chain
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JP2007537743A5 (enExample
JP2007537743A (ja
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ダン，スティーヴン，マーク
リー，イ
ブルター，ジョナサン，マイケル
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イムノコア リミテッド
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Priority claimed from GB0419646A external-priority patent/GB0419646D0/en
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    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2007517396A 2004-05-19 2005-05-10 Ｔ細胞レセプターを改善する方法 Expired - Lifetime JP4972549B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0411125A GB0411125D0 (en) 2004-05-19 2004-05-19 Method of improving T-cell receptors
GB0411125.8 2004-05-19
GB0419646A GB0419646D0 (en) 2004-09-03 2004-09-03 Method of improving t cell receptors
GB0419646.5 2004-09-03
PCT/GB2005/001781 WO2005114215A2 (en) 2004-05-19 2005-05-10 Method of improving t cell receptors

Publications (3)

Publication Number Publication Date
JP2007537743A JP2007537743A (ja) 2007-12-27
JP2007537743A5 JP2007537743A5 (enExample) 2008-06-26
JP4972549B2 true JP4972549B2 (ja) 2012-07-11

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JP2007517396A Expired - Lifetime JP4972549B2 (ja) 2004-05-19 2005-05-10 Ｔ細胞レセプターを改善する方法

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US (1) US7608410B2 (enExample)
EP (1) EP1756278B1 (enExample)
JP (1) JP4972549B2 (enExample)
AT (1) ATE408684T1 (enExample)
AU (1) AU2005246073B2 (enExample)
CA (1) CA2567349C (enExample)
DE (1) DE602005009825D1 (enExample)
NZ (1) NZ550815A (enExample)
WO (1) WO2005114215A2 (enExample)
ZA (1) ZA200609462B (enExample)

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Publication number Publication date
ZA200609462B (en) 2008-04-30
NZ550815A (en) 2009-04-30
DE602005009825D1 (de) 2008-10-30
EP1756278A2 (en) 2007-02-28
WO2005114215A2 (en) 2005-12-01
US7608410B2 (en) 2009-10-27
US20090054257A1 (en) 2009-02-26
HK1105995A1 (en) 2008-02-29
ATE408684T1 (de) 2008-10-15
CA2567349C (en) 2012-11-27
WO2005114215A9 (en) 2006-07-20
CA2567349A1 (en) 2005-12-01
AU2005246073A1 (en) 2005-12-01
EP1756278B1 (en) 2008-09-17
JP2007537743A (ja) 2007-12-27
AU2005246073B2 (en) 2010-10-28
WO2005114215A3 (en) 2006-03-16

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