JP4953477B2 - 改良されたビタミンｄ測定 - Google Patents

改良されたビタミンｄ測定 Download PDF

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Publication number
JP4953477B2
JP4953477B2 JP2009513585A JP2009513585A JP4953477B2 JP 4953477 B2 JP4953477 B2 JP 4953477B2 JP 2009513585 A JP2009513585 A JP 2009513585A JP 2009513585 A JP2009513585 A JP 2009513585A JP 4953477 B2 JP4953477 B2 JP 4953477B2
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JP
Japan
Prior art keywords
vitamin
sample
metabolite
metabolites
release
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JP2009513585A
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English (en)
Japanese (ja)
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JP2009540275A (ja
JP2009540275A5 (https=
Inventor
コーボルト，ウーヴェ
デュルフェル，トーマス
グロル，ミヒァエル
ヘルマン，ルーペルト
デル エルツ，ヘルベルト フォン
プロフ，レオポルト フォン
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/203332—Hydroxyl containing

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2009513585A 2006-06-06 2007-06-04 改良されたビタミンｄ測定 Active JP4953477B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06011605.0 2006-06-06
EP06011605 2006-06-06
PCT/EP2007/004924 WO2007140962A2 (en) 2006-06-06 2007-06-04 Improved measurement of vitamin d

Publications (3)

Publication Number Publication Date
JP2009540275A JP2009540275A (ja) 2009-11-19
JP2009540275A5 JP2009540275A5 (https=) 2010-05-20
JP4953477B2 true JP4953477B2 (ja) 2012-06-13

Family

ID=36646176

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009513585A Active JP4953477B2 (ja) 2006-06-06 2007-06-04 改良されたビタミンｄ測定

Country Status (9)

Country Link
US (1) US8003400B2 (https=)
EP (1) EP2030026B1 (https=)
JP (1) JP4953477B2 (https=)
CN (1) CN101467048B (https=)
AT (1) ATE452343T1 (https=)
CA (1) CA2649338C (https=)
DE (1) DE602007003833D1 (https=)
ES (1) ES2336382T3 (https=)
WO (1) WO2007140962A2 (https=)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
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US7745226B2 (en) 2005-04-06 2010-06-29 Quest Diagnostics Investments Incorporated Methods for detecting vitamin D metabolites
US7972868B2 (en) 2007-11-28 2011-07-05 Quest Diagnostics Investments Incorporated Methods for detecting dihydroxyvitamin D metabolites by mass spectrometry
US8409865B2 (en) * 2008-02-25 2013-04-02 Waters Technologies Corp. Methods and kits for the determination of the presence and quantity of vitamin D analogs in samples
WO2009123199A1 (ja) * 2008-03-31 2009-10-08 積水化学工業株式会社 液体クロマトグラフィー用部材
US8399829B2 (en) 2008-12-18 2013-03-19 Quest Diagnostics Investments Incorporated Vitamin B2 detection by mass spectrometry
GB0903469D0 (en) * 2009-03-02 2009-04-08 Axis Shield Diagnostics Ltd Assay
US7977117B2 (en) 2009-12-03 2011-07-12 Quest Diagnostics Investments Incorprated Vitamin D metabolite determination utilizing mass spectrometry following derivatization
CN102812356B (zh) 2009-12-11 2017-08-08 奎斯特诊断投资公司 多重样品中的甾族化合物的质谱法
US20110240840A1 (en) 2009-12-11 2011-10-06 Quest Diagnostics Investments Incorporated Mass spectrometric determination of cookson-derivatized, non-metabolized vitamin d
JP5351076B2 (ja) * 2010-02-26 2013-11-27 杏林製薬株式会社 オンライン固相抽出による生体試料液中薬剤成分の定量方法
EP2372365A1 (en) * 2010-04-01 2011-10-05 Future Diagnostics B.V. Direct immunoassay for vitamin D
KR101494952B1 (ko) * 2010-05-20 2015-02-23 에프. 호프만-라 로슈 아게 비타민 d 화합물용 방출 시약
EP2635611B1 (en) * 2010-12-28 2017-01-11 Future Diagnostics B.V. Release reagent for vitamin d
WO2014179737A2 (en) 2013-05-03 2014-11-06 The General Hospital Corporation Assays and methods of treatment relating to vitamin d insufficiency
US9052308B2 (en) 2011-01-07 2015-06-09 The General Hospital Corporation Assays and methods of treatment relating to vitamin D insufficiency
EP2661632B1 (en) * 2011-01-07 2018-03-07 The General Hospital Corporation Assays and methods of treatment relating to vitamin d insufficiency
US8785603B2 (en) 2011-05-20 2014-07-22 Siemens Healthcare Diagnostics Inc. Antibodies to 25-hydroxyvitamin D2 and D3 and uses thereof
JP6038945B2 (ja) * 2011-11-18 2016-12-07 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ビタミンｄ化合物に関する遊離試薬
CN102692514A (zh) * 2012-06-21 2012-09-26 厦门大学 血液25-羟基维生素d3腺癌检测试剂盒及其制备方法
US9244083B2 (en) 2012-11-30 2016-01-26 Siemens Healthcare Diagnostics Inc. Compositions and methods for detecting vitamin D
JP6171333B2 (ja) * 2012-12-26 2017-08-02 東ソー株式会社 安定化したビタミンｄ類標準液
KR101840525B1 (ko) 2013-02-06 2018-03-20 후지레비오 가부시키가이샤 비타민 d 의 측정 방법 및 측정용 키트
US9618523B2 (en) 2013-02-28 2017-04-11 Siemens Healthcare Diagnostics Inc. Methods and reagents for determining isomeric analytes
US20140273021A1 (en) * 2013-03-14 2014-09-18 Enzo Biochem, Inc. Vitamin d assays
DE102013205055A1 (de) * 2013-03-21 2014-09-25 Orgentec Diagnostika Gmbh Verfahren und Reagenz zur Bestimmung von Vitamin D Metaboliten
DE102013215580A1 (de) 2013-08-07 2015-02-12 Orgentec Diagnostika Gmbh 25-OH Vitamin D Derivate zur Bestimmung von Vitamin D Metaboliten
CN103467382A (zh) * 2013-09-16 2013-12-25 浙江丽晶化学有限公司 含硫氰酸根离子液体的制备方法及其在聚丙烯腈纺丝加工中的应用
WO2015061598A1 (en) 2013-10-24 2015-04-30 Quidel Corporation Systems and methods for whole blood assays
EP3168619B1 (en) 2014-07-10 2021-10-20 Shenzhen New Industries Biomedical Engineering Co., Ltd. Detection agent for detecting 25-hydroxy vitamin d, preparation method and use
CN104076155B (zh) * 2014-07-10 2016-08-31 深圳市新产业生物医学工程股份有限公司 用于检测25-羟基维生素d的检测剂及制备方法和应用
CN105372337B (zh) * 2014-08-07 2017-11-10 山东达因海洋生物制药股份有限公司 一种检测维生素d滴剂中维生素d含量的方法
WO2017039574A1 (en) * 2015-08-28 2017-03-09 Enzo Life Sciences, Inc. Vitamin d assays
MX379918B (es) * 2015-11-25 2025-03-11 Del Mar Pharmaceuticals Bc Ltd Metodos para analisis y resolucion de preparaciones de dianhidrogalactitol y derivados o analogos del mismo.
CA3005084A1 (en) * 2015-12-11 2017-06-15 Opko Diagnostics, Llc Fluidic systems involving incubation of samples and/or reagents
CN106199015B (zh) * 2016-06-27 2018-08-17 江苏拜明生物技术有限公司 用于血清样品检测的维生素d释放剂、制备方法及应用
CN110068641A (zh) * 2018-01-22 2019-07-30 上海可力梅塔生物医药科技有限公司 25-羟基维生素d2和25-羟基维生素d3的hplc-ms/ms非衍生检测法
CN108982882A (zh) * 2018-06-22 2018-12-11 卢氏实验室公司 一种数字化信息化维生素d快速检测系统和方法
CN110794065A (zh) * 2018-08-03 2020-02-14 郑州泰丰制药有限公司 利用双三元检测骨化三醇软胶囊含量的方法
CN108663461B (zh) * 2018-08-06 2021-03-19 通标标准技术服务(上海)有限公司 一种测定奶粉中维生素d的方法
CN109358148A (zh) * 2018-09-20 2019-02-19 杭州和合医学检验实验室有限公司 血液中维生素d的检验方法
EP4222502A1 (en) * 2020-09-29 2023-08-09 F. Hoffmann-La Roche AG A method for determining the level of vitamin d and metabolites thereof
CN119322137A (zh) * 2024-12-17 2025-01-17 凯莱谱科技股份有限公司 血清维生素d代谢通路代谢物的液相色谱串联质谱检测方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5821020A (en) * 1995-07-14 1998-10-13 Nhh Biologics Vitamin D assay
DE873126T1 (de) 1995-12-29 2000-11-02 A And D Assay, Inc. Markierte vitamin d-verbindungen und deren verwendung
WO1999067211A1 (de) * 1998-06-25 1999-12-29 Immundiagnostik Gesellschaft Für Produktion Und Vertrieb Von Labordiagnostika Mbh FUNKTIONELLE VITAMIN-D-DERIVATE UND VERFAHREN ZUR BESTIMMUNG VON 25-HYDROXY- UND 1α,25-DIHYDROXY-VITAMIN-D
GB0029729D0 (en) * 2000-12-06 2001-01-17 Ids Ltd Method for detection of vitamin D metabolites
US7087395B1 (en) * 2001-01-16 2006-08-08 Quest Diagnostics Investments Incorporated Vitamin D assay
US20040132104A1 (en) 2003-01-07 2004-07-08 Sackrison James L. Vitamin D assay
JP4852614B2 (ja) * 2005-09-29 2012-01-11 エフ．ホフマン−ラ ロシュ アーゲー ビタミンｄ化合物のための放出試薬

Also Published As

Publication number Publication date
JP2009540275A (ja) 2009-11-19
DE602007003833D1 (de) 2010-01-28
US8003400B2 (en) 2011-08-23
ES2336382T3 (es) 2010-04-12
CN101467048B (zh) 2014-04-02
US20100285603A1 (en) 2010-11-11
WO2007140962A3 (en) 2008-01-31
CA2649338C (en) 2011-07-12
CA2649338A1 (en) 2007-12-13
EP2030026B1 (en) 2009-12-16
WO2007140962A2 (en) 2007-12-13
CN101467048A (zh) 2009-06-24
ATE452343T1 (de) 2010-01-15
EP2030026A2 (en) 2009-03-04

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