JP4950028B2 - 質量分析計 - Google Patents

質量分析計 Download PDF

Info

Publication number
JP4950028B2
JP4950028B2 JP2007508963A JP2007508963A JP4950028B2 JP 4950028 B2 JP4950028 B2 JP 4950028B2 JP 2007508963 A JP2007508963 A JP 2007508963A JP 2007508963 A JP2007508963 A JP 2007508963A JP 4950028 B2 JP4950028 B2 JP 4950028B2
Authority
JP
Japan
Prior art keywords
ions
ion
ion mobility
voltage
transient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2007508963A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007534126A (ja
JP2007534126A5 (https=
Inventor
ベイトマン、ロバート、ハロルド
Original Assignee
マイクロマス ユーケー リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by マイクロマス ユーケー リミテッド filed Critical マイクロマス ユーケー リミテッド
Publication of JP2007534126A publication Critical patent/JP2007534126A/ja
Publication of JP2007534126A5 publication Critical patent/JP2007534126A5/ja
Application granted granted Critical
Publication of JP4950028B2 publication Critical patent/JP4950028B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/624—Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/062—Ion guides

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
JP2007508963A 2004-04-20 2005-04-20 質量分析計 Expired - Fee Related JP4950028B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0408751.6 2004-04-20
GBGB0408751.6A GB0408751D0 (en) 2004-04-20 2004-04-20 Mass spectrometer
US58447604P 2004-07-02 2004-07-02
US60/584,476 2004-07-02
PCT/GB2005/001488 WO2005104182A2 (en) 2004-04-20 2005-04-20 Mass spectrometer

Publications (3)

Publication Number Publication Date
JP2007534126A JP2007534126A (ja) 2007-11-22
JP2007534126A5 JP2007534126A5 (https=) 2012-02-23
JP4950028B2 true JP4950028B2 (ja) 2012-06-13

Family

ID=32344045

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007508963A Expired - Fee Related JP4950028B2 (ja) 2004-04-20 2005-04-20 質量分析計

Country Status (6)

Country Link
US (1) US9880129B2 (https=)
EP (1) EP1738398B8 (https=)
JP (1) JP4950028B2 (https=)
CA (1) CA2562802C (https=)
GB (3) GB0408751D0 (https=)
WO (1) WO2005104182A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102133334B1 (ko) * 2020-02-25 2020-07-14 영인에이스 주식회사 질량분석기

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4513488B2 (ja) * 2004-10-06 2010-07-28 株式会社日立製作所 イオンモビリティー分析装置及びイオンモビリティー分析方法
GB0424426D0 (en) 2004-11-04 2004-12-08 Micromass Ltd Mass spectrometer
GB0503010D0 (en) * 2005-02-14 2005-03-16 Micromass Ltd Mass spectrometer
US8440968B2 (en) 2005-02-14 2013-05-14 Micromass Uk Limited Ion-mobility analyser
US8785848B2 (en) * 2007-07-11 2014-07-22 Excellims Corporation Parallel ion mass and ion mobility analysis
US7700913B2 (en) * 2006-03-03 2010-04-20 Ionsense, Inc. Sampling system for use with surface ionization spectroscopy
US8026477B2 (en) 2006-03-03 2011-09-27 Ionsense, Inc. Sampling system for use with surface ionization spectroscopy
CN101063672A (zh) * 2006-04-29 2007-10-31 复旦大学 离子阱阵列
RU2327245C2 (ru) * 2006-05-03 2008-06-20 Евгений Васильевич Мамонтов Способ масс-селективного анализа ионов по времени пролета и устройство для его осуществления
GB0624679D0 (en) * 2006-12-11 2007-01-17 Shimadzu Corp A time-of-flight mass spectrometer and a method of analysing ions in a time-of-flight mass spectrometer
DE102008005281B4 (de) * 2008-01-19 2014-09-18 Airsense Analytics Gmbh Verfahren und Vorrichtung zur Detektion und Identifizierung von Gasen
RU2387043C2 (ru) * 2008-04-10 2010-04-20 Евгений Васильевич Мамонтов Способ формирования двумерного линейного поля и устройство для его осуществления
CN101738429B (zh) 2008-11-26 2013-04-03 岛津分析技术研发（上海）有限公司 离子分离、富集与检测装置
CA2759247C (en) * 2009-04-21 2018-05-08 Excellims Corporation Intelligently controlled spectrometer methods and apparatus
US8207497B2 (en) 2009-05-08 2012-06-26 Ionsense, Inc. Sampling of confined spaces
US8716655B2 (en) * 2009-07-02 2014-05-06 Tricorntech Corporation Integrated ion separation spectrometer
US8822949B2 (en) 2011-02-05 2014-09-02 Ionsense Inc. Apparatus and method for thermal assisted desorption ionization systems
US8901488B1 (en) 2011-04-18 2014-12-02 Ionsense, Inc. Robust, rapid, secure sample manipulation before during and after ionization for a spectroscopy system
WO2013067366A2 (en) 2011-11-02 2013-05-10 Leco Corporation Ion mobility spectrometer
RU2476870C1 (ru) * 2011-11-02 2013-02-27 Федеральное государственное унитарное предприятие "Научно-исследовательский технологический институт имени А.П. Александрова" Способ разделения и регистрации ионов в газе (варианты)
WO2013098598A1 (en) * 2011-12-30 2013-07-04 Dh Technologies Development Pte. Ltd Dc ion funnels
CN104508475B (zh) * 2012-07-31 2018-05-04 莱克公司 具有高吞吐量的离子迁移率谱仪
US10261048B2 (en) * 2012-08-31 2019-04-16 Sensit Ventures, Inc. Spatially alternating asymmetric field ion mobility spectrometer
WO2014059092A1 (en) * 2012-10-10 2014-04-17 Kirk Timothy C Portable evidentiary collection system
US9165744B2 (en) * 2012-10-24 2015-10-20 Varian Semiconductor Equipment Associates, Inc. Apparatus for treating ion beam
US8809769B2 (en) * 2012-11-29 2014-08-19 Bruker Daltonics, Inc. Apparatus and method for cross-flow ion mobility spectrometry
US9916969B2 (en) * 2013-01-14 2018-03-13 Perkinelmer Health Sciences Canada, Inc. Mass analyser interface
CN104112642B (zh) * 2013-04-18 2017-05-24 岛津分析技术研发（上海）有限公司 离子导引装置以及离子导引方法
US9939408B2 (en) 2013-12-24 2018-04-10 Micromass Uk Limited Travelling wave IMS with counterflow of gas
US9874543B2 (en) * 2014-01-14 2018-01-23 Shimadzu Corporation Ion mobility analyzer and mass spectrometer
US10371665B2 (en) * 2014-06-06 2019-08-06 Micromass Uk Limited Mobility selective attenuation
GB201410052D0 (en) * 2014-06-06 2014-07-16 Micromass Ltd Mobility selective attenuation
US9337007B2 (en) 2014-06-15 2016-05-10 Ionsense, Inc. Apparatus and method for generating chemical signatures using differential desorption
US9704700B2 (en) * 2014-06-16 2017-07-11 Purdue Research Foundation Sample analysis systems and methods of use thereof
GB2531292B (en) * 2014-10-14 2019-06-12 Smiths Detection Watford Ltd Method and apparatus
WO2016108126A1 (en) * 2014-12-31 2016-07-07 Dh Technologies Development Pte. Ltd. Differential mobility spectrometry method
WO2017019852A1 (en) * 2015-07-28 2017-02-02 The University Of Florida Research Foundation, Inc. Atmospheric pressure ion guide
WO2017042918A1 (ja) * 2015-09-09 2017-03-16 株式会社島津製作所 イオン移動度分析装置
US9607819B1 (en) * 2016-02-03 2017-03-28 The Charles Stark Draper Laboratory Inc. Non-radioactive, capacitive discharge plasma ion source and method
JP6702412B2 (ja) * 2016-05-13 2020-06-03 株式会社島津製作所 粒子荷電装置
GB201608653D0 (en) * 2016-05-17 2016-06-29 Micromass Ltd Ion mobility seperator
GB2562690B (en) * 2016-09-27 2022-11-02 Micromass Ltd Post-separation mobility analyser
WO2019060538A1 (en) 2017-09-20 2019-03-28 The Trustees Of Indiana University METHODS FOR LIPOPROTEIN RESOLUTION BY MASS SPECTROMETRY
JP7102733B2 (ja) 2018-01-04 2022-07-20 株式会社リコー イオン検出装置及び電界非対称波形イオン移動度分光分析システム
EP3738137A1 (en) 2018-01-12 2020-11-18 The Trustees of Indiana University Electrostatic linear ion trap design for charge detection mass spectrometry
US10741375B2 (en) 2018-05-14 2020-08-11 MOBILion Systems, Inc. Coupling of ion mobility spectrometer with mass spectrometer
JP6874906B2 (ja) * 2018-05-16 2021-05-19 株式会社島津製作所 飛行時間型質量分析装置
GB201808932D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808936D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808890D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
US11373849B2 (en) 2018-05-31 2022-06-28 Micromass Uk Limited Mass spectrometer having fragmentation region
GB201808949D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808893D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808912D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
WO2019229469A1 (en) 2018-05-31 2019-12-05 Micromass Uk Limited Mass spectrometer
GB201808894D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Mass spectrometer
GB201808892D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Mass spectrometer
WO2019236143A1 (en) 2018-06-04 2019-12-12 The Trustees Of Indiana University Apparatus and method for calibrating or resetting a charge detector
CA3100838A1 (en) 2018-06-04 2019-12-12 The Trustees Of Indiana University Charge detection mass spectrometry with real time analysis and signal optimization
EP4391015A3 (en) 2018-06-04 2024-10-09 The Trustees of Indiana University Ion trap array for high throughput charge detection mass spectrometry
WO2019236139A1 (en) 2018-06-04 2019-12-12 The Trustees Of Indiana University Interface for transporting ions from an atmospheric pressure environment to a low pressure environment
JP7398810B2 (ja) 2018-06-04 2023-12-15 ザ・トラスティーズ・オブ・インディアナ・ユニバーシティー 静電線形イオン・トラップにイオンを捕獲する装置および方法
US12089932B2 (en) 2018-06-05 2024-09-17 Trace Matters Scientific Llc Apparatus, system, and method for transferring ions
CN113574632B (zh) 2018-11-20 2024-07-30 印地安纳大学理事会 用于单粒子质谱分析的轨道阱
EP4443473A3 (en) 2018-12-03 2025-01-01 The Trustees of Indiana University Apparatus for simultaneously analyzing multiple ions with an electrostatic linear ion trap
US10651025B1 (en) 2018-12-21 2020-05-12 Thermo Finnigan Llc Orthogonal-flow ion trap array
EP3959741A1 (en) 2019-04-23 2022-03-02 The Trustees of Indiana University Identification of sample subspecies based on particle charge behavior under structural change-inducing sample conditions
EP3972726A4 (en) 2019-05-21 2023-05-10 Mobilion Systems, Inc. VOLTAGE CONTROL FOR ION MOBILITY SEPARATION
WO2021061650A1 (en) * 2019-09-25 2021-04-01 The Trustees Of Indiana University Apparatus and method for pulsed mode charge detection mass spectrometry
CN114728237B (zh) 2019-10-10 2026-02-24 印地安纳大学理事会 用于识别、选择和纯化粒子的系统和方法
US11543384B2 (en) 2019-11-22 2023-01-03 MOBILion Systems, Inc. Mobility based filtering of ions
JP7690209B2 (ja) 2019-12-18 2025-06-10 ザ・トラスティーズ・オブ・インディアナ・ユニバーシティー 電荷測定装置を有する質量分析計
CN111029241B (zh) * 2019-12-19 2024-10-01 中国科学院合肥物质科学研究院 一种离子迁移速度补偿的离子迁移谱仪及方法
EP4100991B1 (en) 2020-02-03 2025-01-29 The Trustees of Indiana University A charge detection mass spectrometer and related method
GB2593667A (en) 2020-02-10 2021-10-06 Thermo Electron Mfg Limited Method and apparatus for separating ions
US12163920B2 (en) 2020-04-06 2024-12-10 MOBILion Systems, Inc. Systems and methods for two-dimensional mobility based filtering of ions
WO2021207235A1 (en) 2020-04-06 2021-10-14 MOBILion Systems, Inc. Systems and methods for two-dimensional mobility based filtering of ions
US11114290B1 (en) 2020-05-07 2021-09-07 Thermo Finnigan Llc Ion funnels and systems incorporating ion funnels
US11581179B2 (en) 2020-05-07 2023-02-14 Thermo Finnigan Llc Ion funnels and systems incorporating ion funnels
US11953466B2 (en) 2020-05-22 2024-04-09 MOBILion Systems, Inc. Methods and apparatus for trapping and accumulation of ions
WO2021247820A1 (en) 2020-06-05 2021-12-09 MOBILion Systems, Inc. Apparatus and methods for ion manipulation having improved duty cycle
CN111710586B (zh) * 2020-06-15 2024-07-05 成都西奇仪器有限公司 一种循环式离子迁移区结构及高分辨率离子迁移谱仪
JP7498653B2 (ja) * 2020-12-09 2024-06-12 シャープ株式会社 イオン生成装置およびイオン移動度分析装置
WO2023203621A1 (ja) * 2022-04-18 2023-10-26 株式会社島津製作所 質量分析装置

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5033895A (https=) 1973-07-25 1975-04-01
US4855595A (en) * 1986-07-03 1989-08-08 Allied-Signal Inc. Electric field control in ion mobility spectrometry
US5420424A (en) 1994-04-29 1995-05-30 Mine Safety Appliances Company Ion mobility spectrometer
US6498342B1 (en) * 1997-06-02 2002-12-24 Advanced Research & Technology Institute Ion separation instrument
US6960761B2 (en) * 1997-06-02 2005-11-01 Advanced Research & Technology Institute Instrument for separating ions in time as functions of preselected ion mobility and ion mass
US5905258A (en) * 1997-06-02 1999-05-18 Advanced Research & Techology Institute Hybrid ion mobility and mass spectrometer
JP2002502086A (ja) * 1998-01-23 2002-01-22 アナリティカ オブ ブランフォード インコーポレーテッド 表面からの質量分光測定
EP1273029B8 (en) 2000-03-14 2006-01-11 National Research Council Canada Faims apparatus and method with laser-based ionization source
AU2001239076A1 (en) * 2000-03-14 2001-09-24 National Research Council Canada Tandem high field asymmetric waveform ion mobility spectrometry (faims)/ion mobility spectrometry
US6933496B2 (en) * 2000-06-23 2005-08-23 The Regents Of The University Of California Ion mobility sensor
US7074232B2 (en) 2000-09-01 2006-07-11 Medtronic Angiolink, Inc. Advanced wound site management systems and methods
US6744043B2 (en) * 2000-12-08 2004-06-01 Mds Inc. Ion mobilty spectrometer incorporating an ion guide in combination with an MS device
EP1405065B1 (en) 2001-06-30 2012-04-11 Dh Technologies Development Pte. Ltd. System for collection of data and identification of unknown ion species in an electric field
US6630662B1 (en) * 2002-04-24 2003-10-07 Mds Inc. Setup for mobility separation of ions implementing an ion guide with an axial field and counterflow of gas
GB2390478B (en) * 2002-05-17 2004-06-02 Micromass Ltd Mass spectrometer
JP3971958B2 (ja) * 2002-05-28 2007-09-05 株式会社日立ハイテクノロジーズ 質量分析装置
US6791078B2 (en) * 2002-06-27 2004-09-14 Micromass Uk Limited Mass spectrometer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102133334B1 (ko) * 2020-02-25 2020-07-14 영인에이스 주식회사 질량분석기

Also Published As

Publication number Publication date
GB2428875A (en) 2007-02-07
GB2413433B (en) 2007-03-21
WO2005104182A2 (en) 2005-11-03
GB2428875B (en) 2008-09-03
GB2413433A (en) 2005-10-26
US20110095175A1 (en) 2011-04-28
EP1738398B8 (en) 2015-07-22
JP2007534126A (ja) 2007-11-22
EP1738398B1 (en) 2015-06-03
WO2005104182A3 (en) 2006-11-02
US9880129B2 (en) 2018-01-30
CA2562802C (en) 2014-06-03
CA2562802A1 (en) 2005-11-03
GB0408751D0 (en) 2004-05-26
GB0619276D0 (en) 2006-11-08
GB0508007D0 (en) 2005-05-25
EP1738398A2 (en) 2007-01-03

Similar Documents

Publication Publication Date Title
JP4950028B2 (ja) 質量分析計
JP2007534126A5 (https=)
US7838826B1 (en) Apparatus and method for parallel flow ion mobility spectrometry combined with mass spectrometry
US20230343575A1 (en) Ion separator
JP5178730B2 (ja) 質量分析計及び質量分析方法
EP2455963B1 (en) Mass spectrometer
JP4467786B2 (ja) 二重イオンガイドインターフェースを有する質量分光計装置およびその作動方法
US6504149B2 (en) Apparatus and method for desolvating and focussing ions for introduction into a mass spectrometer
EP1946354B1 (en) Mass spectrometer
EP2989454B1 (en) Improved ion mobility spectrometer
US10371665B2 (en) Mobility selective attenuation
US11114291B2 (en) Method of separating different ions having similar mass to charge ratios
US11282690B2 (en) Ion guide exit transmission control
US20170076929A1 (en) Multi-Dimensional Ion Separation
GB2515617A (en) Improved ion mobility spectrometer

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20080317

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20110216

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110222

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110516

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20110516

A072 Dismissal of procedure [no reply to invitation to correct request for examination]

Free format text: JAPANESE INTERMEDIATE CODE: A073

Effective date: 20110906

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20111011

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20120104

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20120209

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20120308

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20150316

Year of fee payment: 3

R150 Certificate of patent or registration of utility model

Ref document number: 4950028

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees