JP4944410B2 - Ｖｉｉ因子活性化プロテアーゼ（ｆｓａｐ）のマールブルクｉ多型性に向けられる抗体並びにそれらの製造及び使用 - Google Patents

Ｖｉｉ因子活性化プロテアーゼ（ｆｓａｐ）のマールブルクｉ多型性に向けられる抗体並びにそれらの製造及び使用 Download PDF

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JP4944410B2
JP4944410B2 JP2005240653A JP2005240653A JP4944410B2 JP 4944410 B2 JP4944410 B2 JP 4944410B2 JP 2005240653 A JP2005240653 A JP 2005240653A JP 2005240653 A JP2005240653 A JP 2005240653A JP 4944410 B2 JP4944410 B2 JP 4944410B2
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ハーラルト・アルトハウス
ヘルベルト・シュヴァルツ
ボードー・フィッシャー
トーマス・ヴィッセル
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シーメンス・ヘルスケア・ダイアグノスティックス・プロダクツ・ゲーエムベーハー
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2005240653A 2004-08-24 2005-08-23 Ｖｉｉ因子活性化プロテアーゼ（ｆｓａｐ）のマールブルクｉ多型性に向けられる抗体並びにそれらの製造及び使用 Expired - Fee Related JP4944410B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE102004041104.2 2004-08-24
DE102004041104 2004-08-24
DE102005026163.9 2005-06-06
DE102005026163A DE102005026163A1 (de) 2004-08-24 2005-06-06 Gegen den Marburg I Polymorphismus der Faktor VII aktivierenden Protease (FSAP) gerichtete Antikörper, ihre Herstellung und Verwendung

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JP2006083166A JP2006083166A (ja) 2006-03-30
JP2006083166A5 JP2006083166A5 (enExample) 2008-09-04
JP4944410B2 true JP4944410B2 (ja) 2012-05-30

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JP2005240653A Expired - Fee Related JP4944410B2 (ja) 2004-08-24 2005-08-23 Ｖｉｉ因子活性化プロテアーゼ（ｆｓａｐ）のマールブルクｉ多型性に向けられる抗体並びにそれらの製造及び使用

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US (2) US7622558B2 (enExample)
EP (1) EP1630175B1 (enExample)
JP (1) JP4944410B2 (enExample)
AT (1) ATE398141T1 (enExample)
AU (1) AU2005203794A1 (enExample)
CA (1) CA2516876A1 (enExample)
DE (2) DE102005026163A1 (enExample)
ES (1) ES2308353T3 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060212176A1 (en) * 2005-02-18 2006-09-21 Corum James F Use of electrical power multiplication for power smoothing in power distribution
DE502006005169D1 (de) * 2005-12-22 2009-12-03 Siemens Healthcare Diagnostics Diagnostisches Verfahren zur Erkennung von Trägern der Marburg l-Variante der Faktor VII-aktivierenden Protease (FSAP) anhand differenzieller Modulation der FSAP-Aktivität
RU2395575C1 (ru) * 2008-12-15 2010-07-27 Федеральное государственное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФГУН ГНЦ ВБ "Вектор" Роспотребнадзора) ШТАММ ГИБРИДНЫХ КЛЕТОК ЖИВОТНОГО Mus musculus L. - ПРОДУЦЕНТ МОНОКЛОНАЛЬНЫХ АНТИТЕЛ ДЛЯ ВЫЯВЛЕНИЯ БЕЛКА VP40 ВИРУСА МАРБУРГ (ШТАММ Рорр) (ВАРИАНТЫ), МОНОКЛОНАЛЬНОЕ АНТИТЕЛО, ПРОДУЦИРУЕМОЕ ШТАММОМ (ВАРИАНТЫ), НАБОР ДЛЯ ИММУНОФЕРМЕНТНОЙ ТЕСТ-СИСТЕМЫ ФОРМАТА "СЭНДВИЧ" ДЛЯ ВЫЯВЛЕНИЯ МАТРИКСНОГО БЕЛКА VP40 ВИРУСА МАРБУРГ (ШТАММ Рорр)
RU2393220C1 (ru) * 2008-12-15 2010-06-27 Федеральное государственное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФГУН ГНЦ ВБ "Вектор" Роспотребнадзора) Штамм гибридных клеток животного mus musculus l. 3f9 - продуцент моноклональных антител, пригодных для использования в иммуноферментной системе формата "сэндвич" для выявления белка vp35 вируса марбург, и моноклональные антитела 3f9, продуцируемые указанным штаммом гибридных клеток
GB0916576D0 (en) * 2009-09-22 2009-10-28 Malmsten Nils M Polypeptides and uses thereof
EP2386652A1 (de) 2010-05-12 2011-11-16 Siemens Healthcare Diagnostics Products GmbH Homogenes Verfahren zur Bestimmung der Plasminogenaktivator-aktivierenden Aktivität der FSAP
US9075055B2 (en) 2013-03-15 2015-07-07 Hycor Biomedical, Inc. Device and associated methods for performing luminescence and fluorescence measurements of a sample
JP6485854B2 (ja) * 2014-09-24 2019-03-20 国立研究開発法人国立循環器病研究センター 抗変異型プロテインｓ抗体、該抗体を含む診断用組成物、変異型ヒトプロテインｓの検出方法および該抗体を含むキット

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US3996345A (en) * 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
DE3145082A1 (de) * 1981-11-13 1983-05-19 Behringwerke Ag, 3550 Marburg "ein latex, biologisch aktive latexkonjugate und verfahren zu ihrer herstellung"
DE3545595A1 (de) * 1985-12-21 1987-06-25 Behringwerke Ag Dispersionspolymere, verfahren zu ihrer herstellung und ihre verwendung
US5183766A (en) * 1986-04-18 1993-02-02 Behringwerke Aktiengesellschaft Dispersion polymers, processes for their preparation and their use
DE3613111A1 (de) 1986-04-18 1987-10-22 Behringwerke Ag Dispersionspolymere, verfahren zu ihrer herstellung und ihre verwendung
US5512659A (en) 1989-08-04 1996-04-30 Syntex (U.S.A.) Inc. Compositions useful in heterogeneous immunoassays
AU657134B2 (en) 1991-05-22 1995-03-02 Dade Behring Marburg Gmbh Assay methods utilizing induced luminescence
US5340716A (en) * 1991-06-20 1994-08-23 Snytex (U.S.A.) Inc. Assay method utilizing photoactivated chemiluminescent label
CA2140661A1 (en) * 1992-07-20 1994-02-03 Sharat Singh Novel chemiluminescent compounds and methods of use
JP3498960B2 (ja) 1993-09-03 2004-02-23 デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 蛍光酸素チャンネリングイムノアッセイ
FR2717499B1 (fr) 1994-03-17 1996-05-24 Ulp Fragments d'anticorps recombinants synthétisés et biotinylés dans E. coli, leur utilisation en immunodosages et en purification par immunoaffinité.
DE19903693A1 (de) 1998-04-24 1999-10-28 Centeon Pharma Gmbh Protease zur Aktivierung des Gerinnungsfaktors VII
DE10023923A1 (de) 1999-06-10 2000-12-14 Aventis Behring Gmbh Verfahren zur Bestimmung der Aktivität der Faktor VII-aktivierenden Protease aus Proteinlösungen
US7153679B2 (en) * 2000-07-26 2006-12-26 Aventis Behring Gmbh Marburg I mutant of factor VII activating protease (FSAP) as risk factor for arterial thrombosis
EP1650305B1 (de) * 2000-07-26 2009-08-12 CSL Behring GmbH Mutanten der den Faktor VII aktivierenden Protease und Nachweisverfahren mit spezifischen Antikörpern
GB0108491D0 (en) * 2001-04-04 2001-05-23 Gendaq Ltd Engineering zinc fingers

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Publication number Publication date
US7951910B2 (en) 2011-05-31
ATE398141T1 (de) 2008-07-15
US7622558B2 (en) 2009-11-24
US20100145009A1 (en) 2010-06-10
US20060045879A1 (en) 2006-03-02
DE102005026163A1 (de) 2006-03-02
EP1630175B1 (de) 2008-06-11
EP1630175A1 (de) 2006-03-01
AU2005203794A1 (en) 2006-03-16
CA2516876A1 (en) 2006-02-24
JP2006083166A (ja) 2006-03-30
DE502005004379D1 (de) 2008-07-24
ES2308353T3 (es) 2008-12-01

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