ATE398141T1 - Gegen den marburg i polymorphismus der faktor vii aktivierenden protease (fsap) gerichtete antikörper, ihre herstellung und verwendung - Google Patents
Gegen den marburg i polymorphismus der faktor vii aktivierenden protease (fsap) gerichtete antikörper, ihre herstellung und verwendungInfo
- Publication number
- ATE398141T1 ATE398141T1 AT05018249T AT05018249T ATE398141T1 AT E398141 T1 ATE398141 T1 AT E398141T1 AT 05018249 T AT05018249 T AT 05018249T AT 05018249 T AT05018249 T AT 05018249T AT E398141 T1 ATE398141 T1 AT E398141T1
- Authority
- AT
- Austria
- Prior art keywords
- fsap
- antibodies
- variant
- amino acids
- marburg
- Prior art date
Links
- 101001035951 Homo sapiens Hyaluronan-binding protein 2 Proteins 0.000 title abstract 12
- 102100039238 Hyaluronan-binding protein 2 Human genes 0.000 title abstract 12
- 108091005804 Peptidases Proteins 0.000 title 1
- 239000004365 Protease Substances 0.000 title 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 title 1
- 229940012413 factor vii Drugs 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 3
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 238000009175 antibody therapy Methods 0.000 abstract 1
- 238000003149 assay kit Methods 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 210000005260 human cell Anatomy 0.000 abstract 1
- 210000004408 hybridoma Anatomy 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 239000012873 virucide Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004041104 | 2004-08-24 | ||
| DE102005026163A DE102005026163A1 (de) | 2004-08-24 | 2005-06-06 | Gegen den Marburg I Polymorphismus der Faktor VII aktivierenden Protease (FSAP) gerichtete Antikörper, ihre Herstellung und Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE398141T1 true ATE398141T1 (de) | 2008-07-15 |
Family
ID=35448125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05018249T ATE398141T1 (de) | 2004-08-24 | 2005-08-23 | Gegen den marburg i polymorphismus der faktor vii aktivierenden protease (fsap) gerichtete antikörper, ihre herstellung und verwendung |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7622558B2 (enExample) |
| EP (1) | EP1630175B1 (enExample) |
| JP (1) | JP4944410B2 (enExample) |
| AT (1) | ATE398141T1 (enExample) |
| AU (1) | AU2005203794A1 (enExample) |
| CA (1) | CA2516876A1 (enExample) |
| DE (2) | DE102005026163A1 (enExample) |
| ES (1) | ES2308353T3 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060212176A1 (en) * | 2005-02-18 | 2006-09-21 | Corum James F | Use of electrical power multiplication for power smoothing in power distribution |
| DE502006005169D1 (de) * | 2005-12-22 | 2009-12-03 | Siemens Healthcare Diagnostics | Diagnostisches Verfahren zur Erkennung von Trägern der Marburg l-Variante der Faktor VII-aktivierenden Protease (FSAP) anhand differenzieller Modulation der FSAP-Aktivität |
| RU2395575C1 (ru) * | 2008-12-15 | 2010-07-27 | Федеральное государственное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФГУН ГНЦ ВБ "Вектор" Роспотребнадзора) | ШТАММ ГИБРИДНЫХ КЛЕТОК ЖИВОТНОГО Mus musculus L. - ПРОДУЦЕНТ МОНОКЛОНАЛЬНЫХ АНТИТЕЛ ДЛЯ ВЫЯВЛЕНИЯ БЕЛКА VP40 ВИРУСА МАРБУРГ (ШТАММ Рорр) (ВАРИАНТЫ), МОНОКЛОНАЛЬНОЕ АНТИТЕЛО, ПРОДУЦИРУЕМОЕ ШТАММОМ (ВАРИАНТЫ), НАБОР ДЛЯ ИММУНОФЕРМЕНТНОЙ ТЕСТ-СИСТЕМЫ ФОРМАТА "СЭНДВИЧ" ДЛЯ ВЫЯВЛЕНИЯ МАТРИКСНОГО БЕЛКА VP40 ВИРУСА МАРБУРГ (ШТАММ Рорр) |
| RU2393220C1 (ru) * | 2008-12-15 | 2010-06-27 | Федеральное государственное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФГУН ГНЦ ВБ "Вектор" Роспотребнадзора) | Штамм гибридных клеток животного mus musculus l. 3f9 - продуцент моноклональных антител, пригодных для использования в иммуноферментной системе формата "сэндвич" для выявления белка vp35 вируса марбург, и моноклональные антитела 3f9, продуцируемые указанным штаммом гибридных клеток |
| GB0916576D0 (en) * | 2009-09-22 | 2009-10-28 | Malmsten Nils M | Polypeptides and uses thereof |
| EP2386652A1 (de) | 2010-05-12 | 2011-11-16 | Siemens Healthcare Diagnostics Products GmbH | Homogenes Verfahren zur Bestimmung der Plasminogenaktivator-aktivierenden Aktivität der FSAP |
| US9075055B2 (en) | 2013-03-15 | 2015-07-07 | Hycor Biomedical, Inc. | Device and associated methods for performing luminescence and fluorescence measurements of a sample |
| JP6485854B2 (ja) * | 2014-09-24 | 2019-03-20 | 国立研究開発法人国立循環器病研究センター | 抗変異型プロテインｓ抗体、該抗体を含む診断用組成物、変異型ヒトプロテインｓの検出方法および該抗体を含むキット |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3996345A (en) * | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| DE3145082A1 (de) * | 1981-11-13 | 1983-05-19 | Behringwerke Ag, 3550 Marburg | "ein latex, biologisch aktive latexkonjugate und verfahren zu ihrer herstellung" |
| DE3545595A1 (de) * | 1985-12-21 | 1987-06-25 | Behringwerke Ag | Dispersionspolymere, verfahren zu ihrer herstellung und ihre verwendung |
| US5183766A (en) * | 1986-04-18 | 1993-02-02 | Behringwerke Aktiengesellschaft | Dispersion polymers, processes for their preparation and their use |
| DE3613111A1 (de) | 1986-04-18 | 1987-10-22 | Behringwerke Ag | Dispersionspolymere, verfahren zu ihrer herstellung und ihre verwendung |
| US5512659A (en) | 1989-08-04 | 1996-04-30 | Syntex (U.S.A.) Inc. | Compositions useful in heterogeneous immunoassays |
| AU657134B2 (en) | 1991-05-22 | 1995-03-02 | Dade Behring Marburg Gmbh | Assay methods utilizing induced luminescence |
| US5340716A (en) * | 1991-06-20 | 1994-08-23 | Snytex (U.S.A.) Inc. | Assay method utilizing photoactivated chemiluminescent label |
| CA2140661A1 (en) * | 1992-07-20 | 1994-02-03 | Sharat Singh | Novel chemiluminescent compounds and methods of use |
| JP3498960B2 (ja) | 1993-09-03 | 2004-02-23 | デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | 蛍光酸素チャンネリングイムノアッセイ |
| FR2717499B1 (fr) | 1994-03-17 | 1996-05-24 | Ulp | Fragments d'anticorps recombinants synthétisés et biotinylés dans E. coli, leur utilisation en immunodosages et en purification par immunoaffinité. |
| DE19903693A1 (de) | 1998-04-24 | 1999-10-28 | Centeon Pharma Gmbh | Protease zur Aktivierung des Gerinnungsfaktors VII |
| DE10023923A1 (de) | 1999-06-10 | 2000-12-14 | Aventis Behring Gmbh | Verfahren zur Bestimmung der Aktivität der Faktor VII-aktivierenden Protease aus Proteinlösungen |
| US7153679B2 (en) * | 2000-07-26 | 2006-12-26 | Aventis Behring Gmbh | Marburg I mutant of factor VII activating protease (FSAP) as risk factor for arterial thrombosis |
| EP1650305B1 (de) * | 2000-07-26 | 2009-08-12 | CSL Behring GmbH | Mutanten der den Faktor VII aktivierenden Protease und Nachweisverfahren mit spezifischen Antikörpern |
| GB0108491D0 (en) * | 2001-04-04 | 2001-05-23 | Gendaq Ltd | Engineering zinc fingers |
-
2005
- 2005-06-06 DE DE102005026163A patent/DE102005026163A1/de not_active Withdrawn
- 2005-08-23 AU AU2005203794A patent/AU2005203794A1/en not_active Abandoned
- 2005-08-23 US US11/208,881 patent/US7622558B2/en not_active Expired - Fee Related
- 2005-08-23 DE DE502005004379T patent/DE502005004379D1/de not_active Expired - Lifetime
- 2005-08-23 AT AT05018249T patent/ATE398141T1/de active
- 2005-08-23 EP EP05018249A patent/EP1630175B1/de not_active Expired - Lifetime
- 2005-08-23 JP JP2005240653A patent/JP4944410B2/ja not_active Expired - Fee Related
- 2005-08-23 ES ES05018249T patent/ES2308353T3/es not_active Expired - Lifetime
- 2005-08-24 CA CA002516876A patent/CA2516876A1/en not_active Abandoned
-
2009
- 2009-10-13 US US12/578,337 patent/US7951910B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP4944410B2 (ja) | 2012-05-30 |
| US7951910B2 (en) | 2011-05-31 |
| US7622558B2 (en) | 2009-11-24 |
| US20100145009A1 (en) | 2010-06-10 |
| US20060045879A1 (en) | 2006-03-02 |
| DE102005026163A1 (de) | 2006-03-02 |
| EP1630175B1 (de) | 2008-06-11 |
| EP1630175A1 (de) | 2006-03-01 |
| AU2005203794A1 (en) | 2006-03-16 |
| CA2516876A1 (en) | 2006-02-24 |
| JP2006083166A (ja) | 2006-03-30 |
| DE502005004379D1 (de) | 2008-07-24 |
| ES2308353T3 (es) | 2008-12-01 |
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