JP4944166B2 - 生物由来の天然カルシウムをナノ化状態で提供する方法 - Google Patents
生物由来の天然カルシウムをナノ化状態で提供する方法 Download PDFInfo
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- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title claims description 416
- 239000011575 calcium Substances 0.000 title claims description 416
- 229910052791 calcium Inorganic materials 0.000 title claims description 416
- 238000000034 method Methods 0.000 title claims description 30
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 76
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- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 24
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- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 22
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- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
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- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 2
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- WQNHWIYLCRZRLR-UHFFFAOYSA-N 2-(3-hydroxy-2,5-dioxooxolan-3-yl)acetic acid Chemical compound OC(=O)CC1(O)CC(=O)OC1=O WQNHWIYLCRZRLR-UHFFFAOYSA-N 0.000 description 1
- 206010006956 Calcium deficiency Diseases 0.000 description 1
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- 235000005979 Citrus limon Nutrition 0.000 description 1
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- 240000008790 Musa x paradisiaca Species 0.000 description 1
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 1
- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 1
- 235000011613 Pinus brutia Nutrition 0.000 description 1
- 241000018646 Pinus brutia Species 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 1
- 206010046980 Varicella Diseases 0.000 description 1
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- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 150000008064 anhydrides Chemical class 0.000 description 1
- 235000010208 anthocyanin Nutrition 0.000 description 1
- 229930002877 anthocyanin Natural products 0.000 description 1
- 239000004410 anthocyanin Substances 0.000 description 1
- 150000004636 anthocyanins Chemical class 0.000 description 1
- 229910052586 apatite Inorganic materials 0.000 description 1
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- 159000000007 calcium salts Chemical class 0.000 description 1
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- YGANSGVIUGARFR-UHFFFAOYSA-N dipotassium dioxosilane oxo(oxoalumanyloxy)alumane oxygen(2-) Chemical compound [O--].[K+].[K+].O=[Si]=O.O=[Al]O[Al]=O YGANSGVIUGARFR-UHFFFAOYSA-N 0.000 description 1
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- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
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- SZVJSHCCFOBDDC-UHFFFAOYSA-N iron(II,III) oxide Inorganic materials O=[Fe]O[Fe]O[Fe]=O SZVJSHCCFOBDDC-UHFFFAOYSA-N 0.000 description 1
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- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 description 1
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- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 1
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- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Substances [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 1
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- GFQYVLUOOAAOGM-UHFFFAOYSA-N zirconium(iv) silicate Chemical compound [Zr+4].[O-][Si]([O-])([O-])[O-] GFQYVLUOOAAOGM-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Non-Alcoholic Beverages (AREA)
Description
Claims (26)
- 岩石及び有機酸を含有する水に対して第一の振動処理を施し、さらに、生物由来のカルシウム含有物を加えて第二の振動処理を施す、天然カルシウム溶解溶液の製造方法。
- 前記岩石は火成岩である請求項1に記載の製造方法。
- 前記火成岩は花崗岩である請求項2に記載の製造方法。
- 前記有機酸はクエン酸又は酢酸である請求項1に記載の製造方法。
- 前記生物由来のカルシウム含有物は、貝殻、サンゴ又はこれらの化石から選択される請求項1に記載の製造方法。
- 前記貝殻は帆立貝の貝殻である請求項5に記載の製造方法。
- 前記第一および第二の振動処理は、超音波照射処理を1時間以上施されることを特徴とする請求項1乃至6のいずれか一項に記載の製造方法。
- 請求項1乃至7のいずれか一項に記載の製造方法を用いて作製した天然カルシウム溶解溶液。
- 天然カルシウム濃度が1%以上であり、溶解された天然カルシウムが溶液中に透明に溶解した状態ないしナノ化流動状態(溶液中にナノ化粒子として存在)で含有される、請求項1乃至7のいずれか一項に記載の製造方法を用いて作製した天然カルシウム溶解溶液。
- 天然カルシウム濃度が23%以上であり、溶解された天然カルシウムが溶液中に透明に溶解した状態ないしナノ化流動状態(溶液中にナノ化粒子として存在)で含有される、請求項1乃至7のいずれか一項に記載の製造方法を用いて作製した天然カルシウム溶解溶液。
- 天然カルシウム濃度が23%以下であり、溶解された天然カルシウムが溶液中に透明に溶解した状態で含有される、請求項1乃至7のいずれか一項に記載の製造方法を用いて作製した天然カルシウム溶解溶液。
- 天然カルシウム濃度が少なくとも28%以上であり、溶解された天然カルシウムが溶液中にナノ化流動状態(溶液中にナノ化粒子として存在)で含有される、請求項1乃至7のいずれか一項に記載の製造方法を用いて作製した天然カルシウム溶解溶液。
- 天然カルシウム濃度が50%以上であり、溶解された天然カルシウムが溶液中にナノ化流動状態(溶液中にナノ化粒子として存在)で含有される、請求項1乃至7のいずれか一項に記載の製造方法を用いて作製した天然カルシウム溶解溶液。
- 請求項1乃至7のいずれか一項に記載の製造方法を用いて作製した飽和状態の天然カルシウム溶解溶液に生物由来のカルシウム含有物をさらに加えて溶解し、溶解した天然カルシウム(ナノ粒子)を沈殿凝固及び乾燥させて得られるナノ化天然カルシウム粉末。
- 請求項8乃至13のいずれか一項に記載の天然カルシウム溶解溶液を用いる機能性飲料品。
- 天然カルシウム可溶化溶液100mlに対して可溶化した天然カルシウムを1g以上含有する請求項15に記載の機能性飲料品。
- 請求項15又は16の機能性飲料品を用いて固形化した機能性飲食品。
- 請求項14に記載のナノ化天然カルシウム粉末を用いる機能性食品。
- 前記機能性食品の総量(質量ないし重量)に対して少なくとも1質量%のナノ化天然カルシウム粉末を含有する請求項18に記載の機能性食品。
- 岩石及び有機酸を含有する水に第一の超音波照射処理を施し、さらに、生物由来のカルシウム含有物を加えて、第二の超音波照射処理を施すことで、該生物由来のカルシウム含有物の天然カルシウムを溶液中に安定化する、天然カルシウム安定化方法。
- 前記岩石は火成岩である請求項20に記載の天然カルシウム安定化方法。
- 前記火成岩は花崗岩である請求項21に記載の天然カルシウム安定化方法。
- 前記有機酸はクエン酸である請求項20に記載の天然カルシウム安定化方法。
- 前記生物由来のカルシウム含有物は貝類の貝殻、サンゴ、又はこれらの化石である請求項20に記載の天然カルシウム安定化方法。
- 前記貝殻は帆立貝の貝殻である請求項24に記載の天然カルシウム安定化方法。
- 前記第一の超音波照射処理は1時間以上であり、前記第二の超音波照射処理は1時間以上である請求項20乃至25のいずれか一項に記載の天然カルシウム安定化方法。
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