JP4861326B2 - 埋め込み可能または移植可能な生体材料の製造のための滅菌方法 - Google Patents
埋め込み可能または移植可能な生体材料の製造のための滅菌方法 Download PDFInfo
- Publication number
- JP4861326B2 JP4861326B2 JP2007531586A JP2007531586A JP4861326B2 JP 4861326 B2 JP4861326 B2 JP 4861326B2 JP 2007531586 A JP2007531586 A JP 2007531586A JP 2007531586 A JP2007531586 A JP 2007531586A JP 4861326 B2 JP4861326 B2 JP 4861326B2
- Authority
- JP
- Japan
- Prior art keywords
- sterilization method
- microorganisms
- sterilization
- implantable
- combination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0205—Chemical aspects
- A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
- A01N1/0215—Disinfecting agents, e.g. antimicrobials for preserving living parts
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/915—Method or apparatus for preparing biological material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/92—Method or apparatus for preparing or treating prosthetic
Description
Claims (5)
- 下記:
1.微生物の成長を妨げ、該微生物を分離するための抗生物質溶液中における原材料の処理;
2.デオキシコール酸を除去し、表面からの分離された微生物をすすぎ流すための水溶液中における後続の第1の洗浄プロセスと組み合わせて、微生物の生育を妨げ、該微生物を分離するためのデオキシコール酸中における前記材料のさらなる処理;
3.水溶液中における後続の第2の洗浄プロセスと組み合わせて、溶血性、抗菌性、抗ウイルス性、および微生物の分離作用を有する、デオキシコール酸のさらなる除去のための界面活性リポタンパク質溶液中における前記材料のさらなる処理;および
4.水溶液中における後続の第3の洗浄プロセスと組み合わせて、殺真菌、殺菌および抗ウイルス作用を有し、さらなる分離と微生物の完全な破壊との組み合わせのための第一級アルコール中における前記材料のさらなる処理、
の順番で続き、組み合わされた化学的および物理的効果を有する4回の滅菌ステップを含むことを特徴とする、動物またはヒト起源の移植可能または埋め込み可能な生体物質の滅菌方法。 - 4つの滅菌ステップおよび洗浄ステップが、特定の時間間隔で行われる、請求項1記載の滅菌方法。
- 70%エタノールを第一級アルコールとして用いる、請求項1記載の滅菌方法。
- 1つの洗浄プロセスが多数の連続的なステップを含む、請求項1記載の滅菌方法。
- ナトリウム塩水溶液が、洗浄剤として用いられる、請求項1記載の滅菌方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004047247.5 | 2004-09-22 | ||
DE102004047247A DE102004047247B3 (de) | 2004-09-22 | 2004-09-22 | Sterilisationsverfahren zur Herstellung von implantierbarem oder transplantierbarem biologischem Material |
PCT/DE2005/001595 WO2006032240A1 (de) | 2004-09-22 | 2005-09-08 | Sterilisationsverfahren zur herstellung von implantierbarem oder transplantierbarem biologischem material |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2008513066A JP2008513066A (ja) | 2008-05-01 |
JP4861326B2 true JP4861326B2 (ja) | 2012-01-25 |
Family
ID=35447656
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007531586A Expired - Fee Related JP4861326B2 (ja) | 2004-09-22 | 2005-09-08 | 埋め込み可能または移植可能な生体材料の製造のための滅菌方法 |
Country Status (15)
Country | Link |
---|---|
US (1) | US7438850B2 (ja) |
EP (1) | EP1791422B1 (ja) |
JP (1) | JP4861326B2 (ja) |
CN (1) | CN101035430B (ja) |
AT (1) | ATE432006T1 (ja) |
AU (1) | AU2005287780B2 (ja) |
BR (1) | BRPI0515694A (ja) |
CA (1) | CA2597365C (ja) |
DE (2) | DE102004047247B3 (ja) |
DK (1) | DK1791422T3 (ja) |
ES (1) | ES2326183T3 (ja) |
PL (1) | PL1791422T3 (ja) |
PT (1) | PT1791422E (ja) |
RU (1) | RU2353092C2 (ja) |
WO (1) | WO2006032240A1 (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2951549B1 (fr) | 2009-10-15 | 2013-08-23 | Olivier Schussler | Procede d'obtention de bioprotheses medicales implantables |
WO2016116895A1 (en) | 2015-01-22 | 2016-07-28 | University Of The Free State | Detoxification and stabilization of implantable or transplantable biological material |
CN111202081B (zh) * | 2020-01-15 | 2021-09-21 | 四川大学 | 一种干燥胶原基生物材料的灭菌方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63190832A (ja) * | 1987-02-02 | 1988-08-08 | Norio Tada | 抗菌剤 |
WO2002049681A1 (de) * | 2000-12-20 | 2002-06-27 | Auto Tissue Gmbh | Verfahren zur dezellularisierung von fremdmaterial zur herstellung von bioprothesen |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4553974A (en) * | 1984-08-14 | 1985-11-19 | Mayo Foundation | Treatment of collagenous tissue with glutaraldehyde and aminodiphosphonate calcification inhibitor |
CN1052632C (zh) * | 1993-04-16 | 2000-05-24 | 成都科技大学 | 对胶原组织人工瓣膜材料缓钙化的方法 |
US5558875A (en) * | 1994-06-06 | 1996-09-24 | Wang; Su | Method of preparing collagenous tissue |
US5741782A (en) | 1996-03-29 | 1998-04-21 | Cryolife, Inc. | Antibiotic cocktail and method of use |
DE10060660A1 (de) | 2000-12-06 | 2002-06-20 | Frey Rainer | Verfahren zur Konservierung von biologischen Prothesen, konservierte biologische Prothese und Konservierungslösung |
GB2375771A (en) * | 2001-05-24 | 2002-11-27 | Univ Leeds | Decellularisation of tissue implant material |
DE10258121B3 (de) * | 2002-12-06 | 2004-03-18 | Auto Tissue Gmbh | Verfahren zur Herstellung von Bioprothesen |
-
2004
- 2004-09-22 DE DE102004047247A patent/DE102004047247B3/de not_active Expired - Fee Related
-
2005
- 2005-09-08 JP JP2007531586A patent/JP4861326B2/ja not_active Expired - Fee Related
- 2005-09-08 CN CN200580031968XA patent/CN101035430B/zh not_active Expired - Fee Related
- 2005-09-08 ES ES05789871T patent/ES2326183T3/es active Active
- 2005-09-08 US US11/663,443 patent/US7438850B2/en not_active Expired - Fee Related
- 2005-09-08 EP EP05789871A patent/EP1791422B1/de not_active Not-in-force
- 2005-09-08 AT AT05789871T patent/ATE432006T1/de active
- 2005-09-08 CA CA2597365A patent/CA2597365C/en not_active Expired - Fee Related
- 2005-09-08 WO PCT/DE2005/001595 patent/WO2006032240A1/de active Application Filing
- 2005-09-08 DE DE502005007365T patent/DE502005007365D1/de active Active
- 2005-09-08 DK DK05789871T patent/DK1791422T3/da active
- 2005-09-08 PT PT05789871T patent/PT1791422E/pt unknown
- 2005-09-08 RU RU2007115041/15A patent/RU2353092C2/ru not_active IP Right Cessation
- 2005-09-08 AU AU2005287780A patent/AU2005287780B2/en not_active Ceased
- 2005-09-08 PL PL05789871T patent/PL1791422T3/pl unknown
- 2005-09-08 BR BRPI0515694-7A patent/BRPI0515694A/pt not_active IP Right Cessation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63190832A (ja) * | 1987-02-02 | 1988-08-08 | Norio Tada | 抗菌剤 |
WO2002049681A1 (de) * | 2000-12-20 | 2002-06-27 | Auto Tissue Gmbh | Verfahren zur dezellularisierung von fremdmaterial zur herstellung von bioprothesen |
Also Published As
Publication number | Publication date |
---|---|
DE102004047247B3 (de) | 2006-03-16 |
WO2006032240A1 (de) | 2006-03-30 |
AU2005287780B2 (en) | 2008-11-27 |
BRPI0515694A (pt) | 2007-10-23 |
PT1791422E (pt) | 2009-08-07 |
EP1791422A1 (de) | 2007-06-06 |
JP2008513066A (ja) | 2008-05-01 |
DK1791422T3 (da) | 2009-08-24 |
ES2326183T3 (es) | 2009-10-02 |
CA2597365A1 (en) | 2006-03-30 |
US7438850B2 (en) | 2008-10-21 |
DE502005007365D1 (de) | 2009-07-09 |
CN101035430B (zh) | 2011-06-29 |
CN101035430A (zh) | 2007-09-12 |
ATE432006T1 (de) | 2009-06-15 |
PL1791422T3 (pl) | 2009-10-30 |
RU2353092C2 (ru) | 2009-04-27 |
EP1791422B1 (de) | 2009-05-27 |
RU2007115041A (ru) | 2008-10-27 |
US20080089806A1 (en) | 2008-04-17 |
CA2597365C (en) | 2010-12-14 |
AU2005287780A1 (en) | 2006-03-30 |
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