JP4861178B2 - 生体適合性および生物学的安定性を有する医療用品表面コーティング - Google Patents

生体適合性および生物学的安定性を有する医療用品表面コーティング Download PDF

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Publication number
JP4861178B2
JP4861178B2 JP2006527276A JP2006527276A JP4861178B2 JP 4861178 B2 JP4861178 B2 JP 4861178B2 JP 2006527276 A JP2006527276 A JP 2006527276A JP 2006527276 A JP2006527276 A JP 2006527276A JP 4861178 B2 JP4861178 B2 JP 4861178B2
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Japan
Prior art keywords
layer
polysulfone
medical product
polymer
active agent
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Expired - Fee Related
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JP2006527276A
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English (en)
Japanese (ja)
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JP2007508039A5 (https=
JP2007508039A (ja
Inventor
ホレス，ローラント
ホフマン，ミヒャエル
ファウスト，フォルカー
ホフマン，エーリカ
ビアーゼ，ドナート ディ
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Hemoteq AG
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Hemoteq AG
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Publication date
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Priority claimed from PCT/DE2004/002184 external-priority patent/WO2005032611A2/de
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Publication of JP2007508039A5 publication Critical patent/JP2007508039A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D181/00—Coating compositions based on macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing sulfur, with or without nitrogen, oxygen, or carbon only; Coating compositions based on polysulfones; Coating compositions based on derivatives of such polymers
    • C09D181/06—Polysulfones; Polyethersulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/06—Use of macromolecular materials
    • A61L33/068—Use of macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Materials For Medical Uses (AREA)
JP2006527276A 2003-09-29 2004-09-29 生体適合性および生物学的安定性を有する医療用品表面コーティング Expired - Fee Related JP4861178B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
DE10345132 2003-09-29
DE10345132.3 2003-09-29
US51629503P 2003-11-03 2003-11-03
US60/516,295 2003-11-03
DE102004020856A DE102004020856A1 (de) 2003-09-29 2004-04-28 Biokompatible, biostabile Beschichtung von medizinischen Oberflächen
DE102004020856.5 2004-04-28
US57158204P 2004-05-17 2004-05-17
US60/571,582 2004-05-17
PCT/DE2004/002184 WO2005032611A2 (de) 2003-09-29 2004-09-29 Biokompatible, biostabile beschichtung von medizinischen oberflächen

Publications (3)

Publication Number Publication Date
JP2007508039A JP2007508039A (ja) 2007-04-05
JP2007508039A5 JP2007508039A5 (https=) 2010-08-26
JP4861178B2 true JP4861178B2 (ja) 2012-01-25

Family

ID=34306136

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006527276A Expired - Fee Related JP4861178B2 (ja) 2003-09-29 2004-09-29 生体適合性および生物学的安定性を有する医療用品表面コーティング

Country Status (3)

Country Link
JP (1) JP4861178B2 (https=)
DE (1) DE102004020856A1 (https=)
OA (1) OA13261A (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009523489A (ja) * 2006-01-12 2009-06-25 ボストン サイエンティフィック リミテッド 被覆医療用具及びその製造方法

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2046410B1 (de) * 2006-07-03 2019-04-10 Hemoteq AG Herstellung, verfahren und verwendung von wirkstofffreisetzenden medizinprodukten zur permanenten offenhaltung von blutgefässen
CA2673991C (en) * 2007-01-21 2012-02-07 Hemoteq Ag Methods for coating catheter balloons with a defined quantity of active agent
US9192697B2 (en) 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
DE102008043724A1 (de) 2008-11-13 2010-05-20 Biotronik Vi Patent Ag Erhöhung der Effizienz pharmazeutische Wirkstoffe-freisetzender Medizinprodukte durch Kombination mit einem Inhibitor des Transportproteins P-Glycoprotein
ES2550634T3 (es) 2009-07-10 2015-11-11 Boston Scientific Scimed, Inc. Uso de nanocristales para un balón de suministro de fármaco
EP2453938B1 (en) 2009-07-17 2015-08-19 Boston Scientific Scimed, Inc. Nucleation of drug delivery balloons to provide improved crystal size and density
CN102274550B (zh) * 2010-06-13 2014-11-26 上海微创医疗器械（集团）有限公司 一种介入医疗器械
US8889211B2 (en) 2010-09-02 2014-11-18 Boston Scientific Scimed, Inc. Coating process for drug delivery balloons using heat-induced rewrap memory
WO2013022458A1 (en) 2011-08-05 2013-02-14 Boston Scientific Scimed, Inc. Methods of converting amorphous drug substance into crystalline form
WO2013028208A1 (en) 2011-08-25 2013-02-28 Boston Scientific Scimed, Inc. Medical device with crystalline drug coating
US12569655B2 (en) 2017-04-24 2026-03-10 Longeviti Neuro Solutions, Inc. Cerebral spinal fluid shunt plug
US11045632B2 (en) 2017-04-24 2021-06-29 Longeviti Neuro Solutions Llc Cerebral spinal fluid shunt plug
US11439798B2 (en) 2017-04-24 2022-09-13 Longeviti Neuro Solutions Llc Cerebral spinal fluid shunt plug
DE102018110582A1 (de) * 2018-05-03 2019-11-07 Biotronik Ag Verminderung der Rissbildung in Polymerschichten von abbaubaren Scaffolds

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0564657A (ja) * 1991-02-27 1993-03-19 Mitsui Toatsu Chem Inc 外科用フイラメントの製造方法
WO1999019381A1 (en) * 1997-10-09 1999-04-22 Teijin Limited Medical material containing fluorinated polysulfone having excellent antithrombotic activity
JP2002504842A (ja) * 1997-06-24 2002-02-12 シェリング アクチェンゲゼルシャフト フルオロアルキル基でコートされたステント、その製造法、及び再狭窄防止への利用
JP2002527534A (ja) * 1998-10-13 2002-08-27 ガンブロ アクチボラグ 生体適合性ポリマーフィルム
JP2002534165A (ja) * 1998-12-31 2002-10-15 アンジオテック ファーマシューティカルズ，インコーポレイテッド 生物活性被覆を備えたステント移植片
JP2004131566A (ja) * 2002-10-09 2004-04-30 Asahi Kasei Corp 分岐ポリエチレンオキシド−合成高分子ブロック共重合体
JP2007505704A (ja) * 2003-09-16 2007-03-15 アンジオテック バイオコーティングズ コーポレイション 複数層ポリマーコーティングを有する薬物添加ステント
JP2007515199A (ja) * 2003-05-08 2007-06-14 アドヴァンスド カーディオヴァスキュラー システムズ， インコーポレイテッド 親水性添加剤を含むステント用コーティング

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EP0432141A3 (en) * 1984-03-30 1991-08-21 Osteonics Biomaterials, Inc. A femoral stem for permanent implantation into the natural femur
US5192326A (en) * 1990-12-21 1993-03-09 Pfizer Hospital Products Group, Inc. Hydrogel bead intervertebral disc nucleus
US20020055710A1 (en) * 1998-04-30 2002-05-09 Ronald J. Tuch Medical device for delivering a therapeutic agent and method of preparation
IL115321A (en) * 1994-09-16 2000-08-31 Univ Ramot Thromboresistant surface treatment for biomaterials
DE19539449A1 (de) * 1995-10-24 1997-04-30 Biotronik Mess & Therapieg Verfahren zur Herstellung intraluminaler Stents aus bioresorbierbarem Polymermaterial
WO2002041931A2 (en) * 2000-11-27 2002-05-30 Medtronic, Inc. Stents and methods for preparing stents
KR100679990B1 (ko) * 2001-10-15 2007-02-08 헤모텍 게엠베하 재협착증의 방지를 위한 스텐트의 코팅

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0564657A (ja) * 1991-02-27 1993-03-19 Mitsui Toatsu Chem Inc 外科用フイラメントの製造方法
JP2002504842A (ja) * 1997-06-24 2002-02-12 シェリング アクチェンゲゼルシャフト フルオロアルキル基でコートされたステント、その製造法、及び再狭窄防止への利用
WO1999019381A1 (en) * 1997-10-09 1999-04-22 Teijin Limited Medical material containing fluorinated polysulfone having excellent antithrombotic activity
JP2002527534A (ja) * 1998-10-13 2002-08-27 ガンブロ アクチボラグ 生体適合性ポリマーフィルム
JP2002534165A (ja) * 1998-12-31 2002-10-15 アンジオテック ファーマシューティカルズ，インコーポレイテッド 生物活性被覆を備えたステント移植片
JP2004131566A (ja) * 2002-10-09 2004-04-30 Asahi Kasei Corp 分岐ポリエチレンオキシド−合成高分子ブロック共重合体
JP2007515199A (ja) * 2003-05-08 2007-06-14 アドヴァンスド カーディオヴァスキュラー システムズ， インコーポレイテッド 親水性添加剤を含むステント用コーティング
JP2007505704A (ja) * 2003-09-16 2007-03-15 アンジオテック バイオコーティングズ コーポレイション 複数層ポリマーコーティングを有する薬物添加ステント

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009523489A (ja) * 2006-01-12 2009-06-25 ボストン サイエンティフィック リミテッド 被覆医療用具及びその製造方法

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Publication number Publication date
OA13261A (en) 2007-01-31
DE102004020856A1 (de) 2005-04-14
JP2007508039A (ja) 2007-04-05

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