JP4827357B2 - ヒト前立腺癌において発現されるヘビ状膜貫通抗原およびその使用方法 - Google Patents

ヒト前立腺癌において発現されるヘビ状膜貫通抗原およびその使用方法 Download PDF

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JP4827357B2
JP4827357B2 JP2001541031A JP2001541031A JP4827357B2 JP 4827357 B2 JP4827357 B2 JP 4827357B2 JP 2001541031 A JP2001541031 A JP 2001541031A JP 2001541031 A JP2001541031 A JP 2001541031A JP 4827357 B2 JP4827357 B2 JP 4827357B2
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steap
protein
cells
expression
cancer
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JP2003517306A (ja
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ダニエル イー． エイチ． アファー，
レネ エス． ハバート，
アーサー ビー． ライタノ，
ダグラス シー． サフラン，
スティーブ チャッペル ミッチェル，
メアリー ファリス，
アヤ ジャコボビッツ，
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アジェンシス，インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2600/154—Methylation markers
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

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  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • General Engineering & Computer Science (AREA)
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JP2001541031A 1999-12-06 2000-12-06 ヒト前立腺癌において発現されるヘビ状膜貫通抗原およびその使用方法 Expired - Lifetime JP4827357B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/455,486 1999-12-06
US09/455,486 US6833438B1 (en) 1999-06-01 1999-12-06 Serpentine transmembrane antigens expressed in human cancers and uses thereof
PCT/US2000/033040 WO2001040276A2 (en) 1999-12-06 2000-12-06 Serpentine transmembrane antigens expressed in human prostate cancers and uses thereof

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2005365540A Division JP2006204290A (ja) 1999-12-06 2005-12-19 ヒト前立腺癌において発現されるヘビ状膜貫通抗原およびその使用方法
JP2010212334A Division JP2011062201A (ja) 1999-12-06 2010-09-22 ヒト前立腺癌において発現されるヘビ状膜貫通抗原およびその使用方法

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JP2003517306A JP2003517306A (ja) 2003-05-27
JP4827357B2 true JP4827357B2 (ja) 2011-11-30

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JP2001541031A Expired - Lifetime JP4827357B2 (ja) 1999-12-06 2000-12-06 ヒト前立腺癌において発現されるヘビ状膜貫通抗原およびその使用方法
JP2005365540A Withdrawn JP2006204290A (ja) 1999-12-06 2005-12-19 ヒト前立腺癌において発現されるヘビ状膜貫通抗原およびその使用方法
JP2010212334A Pending JP2011062201A (ja) 1999-12-06 2010-09-22 ヒト前立腺癌において発現されるヘビ状膜貫通抗原およびその使用方法

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JP2005365540A Withdrawn JP2006204290A (ja) 1999-12-06 2005-12-19 ヒト前立腺癌において発現されるヘビ状膜貫通抗原およびその使用方法
JP2010212334A Pending JP2011062201A (ja) 1999-12-06 2010-09-22 ヒト前立腺癌において発現されるヘビ状膜貫通抗原およびその使用方法

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EP (2) EP1642909A3 (enExample)
JP (3) JP4827357B2 (enExample)
AT (1) ATE456578T1 (enExample)
AU (2) AU775366B2 (enExample)
CA (1) CA2395053C (enExample)
CY (1) CY1111034T1 (enExample)
DE (1) DE60043784D1 (enExample)
DK (1) DK1244705T3 (enExample)
ES (1) ES2340249T3 (enExample)
IL (3) IL150018A0 (enExample)
PT (1) PT1244705E (enExample)
WO (1) WO2001040276A2 (enExample)

Cited By (1)

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JP2010500568A (ja) * 2006-08-09 2010-01-07 ホームステッド クリニカル コーポレイション 器官特異的蛋白質およびその使用方法

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US20060052321A1 (en) 2002-04-05 2006-03-09 Raitano Arthur B Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer
US20030149531A1 (en) 2000-12-06 2003-08-07 Hubert Rene S. Serpentine transmembrane antigens expressed in human cancers and uses thereof
US20040141975A1 (en) 1998-06-01 2004-07-22 Raitano Arthur B. Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer
DE69941187D1 (de) 1998-06-01 2009-09-10 Agensys Inc Serpentintransmembranantigene exprimiert in menschlichem krebs und deren verwendungen
US6833438B1 (en) 1999-06-01 2004-12-21 Agensys, Inc. Serpentine transmembrane antigens expressed in human cancers and uses thereof
US7611892B2 (en) 2000-03-24 2009-11-03 President And Fellows Of Harvard College Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
WO2005114216A2 (en) * 2005-02-22 2005-12-01 Biomedisinsk Innovasjon As Stamp2 nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
US7189565B2 (en) 2001-03-23 2007-03-13 Fahri Saatcioglu Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
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US7494646B2 (en) 2001-09-06 2009-02-24 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
WO2003022995A2 (en) * 2001-09-06 2003-03-20 Agensys, Inc. Nucleic acid and corresponding protein entitled steap-1 useful in treatment and detection of cancer
MXPA04009728A (es) * 2002-04-05 2005-06-08 Agenysys Inc Acido nucleico y proteina correspondiente titulada 98p4b6 en el tratamiento y deteccion del cancer.
WO2004016643A2 (en) * 2002-08-16 2004-02-26 Yeda Research And Development Co. Ltd. Tumor associated antigen, peptides thereof, and use of same as anti-tumor vaccines
JP5840351B2 (ja) 2002-09-06 2016-01-06 アジェンシス，インコーポレイテッド 癌の処置および検出において有用な９８ｐ４ｂ６と称される、核酸および対応タンパク質
KR20060006775A (ko) * 2003-03-05 2006-01-19 이넥스 바이오테크놀로지 인크. 세포자살을 억제하는 유도된 막 횡단 항체
ES2605443T3 (es) 2003-11-06 2017-03-14 Seattle Genetics, Inc. Conjugados de auristatina con anticuerpos anti-HER2 o anti-CD22 y su uso en terapia
BRPI0418766B8 (pt) 2004-04-22 2021-05-25 Agensys Inc anticorpo ou seu fragmento, vetor, composição farmacêutica, ensaio e método para detectar a presença de proteína steap-1, bem como método para distribuir um agente citotóxico ou um agente de diagnóstico
JP4191189B2 (ja) 2005-12-08 2008-12-03 康生 梅津 がん関連遺伝子活性化能を有するペプチド
PT2845866T (pt) 2006-10-27 2017-08-09 Genentech Inc Anticorpos e imunoconjugados e utilizações dos mesmos
JP5394246B2 (ja) * 2007-03-30 2014-01-22 ジェネンテック， インコーポレイテッド 抗体及びイムノコンジュゲートとこれらの使用方法
PT2474557E (pt) 2007-07-16 2014-12-03 Genentech Inc Anticorpos e imunoconjugados anti-cd79b e métodos de utilização
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KR102520731B1 (ko) * 2016-09-23 2023-04-14 리제너론 파아마슈티컬스, 인크. 항-steap2 항체, 항체-약물 컨쥬게이트, 및 steap2 및 cd3에 결합하는 이중특이적 항원-결합 분자, 및 이의 용도
WO2018094143A1 (en) 2016-11-17 2018-05-24 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
KR20240044544A (ko) 2017-03-03 2024-04-04 씨젠 인크. 글리칸-상호작용 화합물 및 사용 방법
PE20200010A1 (es) 2017-04-03 2020-01-06 Hoffmann La Roche Anticuerpos que se unen a steap-1
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WO1998018489A1 (en) * 1996-10-30 1998-05-07 The Uab Research Foundation Enhancement of tumor cell chemosensitivity and radiosensitivity using single chain intracellular antibodies
WO1999061469A2 (en) * 1998-05-22 1999-12-02 Incyte Pharmaceuticals, Inc. Prostate growth-associated membrane proteins
WO1999062941A2 (en) * 1998-06-01 1999-12-09 Urogenesys, Inc. Serpentine transmembrane antigens expressed in human cancers and uses thereof

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Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
WO1994009150A1 (en) * 1992-10-08 1994-04-28 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Monoclonal antibodies to prostate cells
WO1998018489A1 (en) * 1996-10-30 1998-05-07 The Uab Research Foundation Enhancement of tumor cell chemosensitivity and radiosensitivity using single chain intracellular antibodies
WO1999061469A2 (en) * 1998-05-22 1999-12-02 Incyte Pharmaceuticals, Inc. Prostate growth-associated membrane proteins
WO1999062941A2 (en) * 1998-06-01 1999-12-09 Urogenesys, Inc. Serpentine transmembrane antigens expressed in human cancers and uses thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010500568A (ja) * 2006-08-09 2010-01-07 ホームステッド クリニカル コーポレイション 器官特異的蛋白質およびその使用方法

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PT1244705E (pt) 2010-05-04
EP1244705A2 (en) 2002-10-02
EP1642909A2 (en) 2006-04-05
AU2062901A (en) 2001-06-12
WO2001040276A3 (en) 2002-01-10
IL150018A (en) 2011-04-28
CA2395053C (en) 2012-05-29
JP2006204290A (ja) 2006-08-10
EP1642909A3 (en) 2006-04-12
DK1244705T3 (da) 2010-05-31
IL199275A0 (en) 2011-07-31
IL150018A0 (en) 2002-12-01
AU775366B2 (en) 2004-07-29
CA2395053A1 (en) 2001-06-07
WO2001040276A2 (en) 2001-06-07
JP2011062201A (ja) 2011-03-31
DE60043784D1 (de) 2010-03-18
AU2004224964B2 (en) 2008-10-02
ES2340249T3 (es) 2010-06-01
CY1111034T1 (el) 2015-08-05
JP2003517306A (ja) 2003-05-27
ATE456578T1 (de) 2010-02-15
EP1244705B1 (en) 2010-01-27
AU2004224964A1 (en) 2004-11-25

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