DE60043784D1 - Serpentinetransmembranrezeptoren exprimiert in menschlichem prostatakrebs und ihre verwendungen - Google Patents
Serpentinetransmembranrezeptoren exprimiert in menschlichem prostatakrebs und ihre verwendungenInfo
- Publication number
- DE60043784D1 DE60043784D1 DE60043784T DE60043784T DE60043784D1 DE 60043784 D1 DE60043784 D1 DE 60043784D1 DE 60043784 T DE60043784 T DE 60043784T DE 60043784 T DE60043784 T DE 60043784T DE 60043784 D1 DE60043784 D1 DE 60043784D1
- Authority
- DE
- Germany
- Prior art keywords
- steap
- family
- human
- prostate cancer
- expressed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/455,486 US6833438B1 (en) | 1999-06-01 | 1999-12-06 | Serpentine transmembrane antigens expressed in human cancers and uses thereof |
PCT/US2000/033040 WO2001040276A2 (en) | 1999-12-06 | 2000-12-06 | Serpentine transmembrane antigens expressed in human prostate cancers and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60043784D1 true DE60043784D1 (de) | 2010-03-18 |
Family
ID=23809010
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60043784T Expired - Lifetime DE60043784D1 (de) | 1999-12-06 | 2000-12-06 | Serpentinetransmembranrezeptoren exprimiert in menschlichem prostatakrebs und ihre verwendungen |
Country Status (12)
Country | Link |
---|---|
EP (2) | EP1642909A3 (de) |
JP (3) | JP4827357B2 (de) |
AT (1) | ATE456578T1 (de) |
AU (2) | AU775366B2 (de) |
CA (1) | CA2395053C (de) |
CY (1) | CY1111034T1 (de) |
DE (1) | DE60043784D1 (de) |
DK (1) | DK1244705T3 (de) |
ES (1) | ES2340249T3 (de) |
IL (3) | IL150018A0 (de) |
PT (1) | PT1244705E (de) |
WO (1) | WO2001040276A2 (de) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030149531A1 (en) | 2000-12-06 | 2003-08-07 | Hubert Rene S. | Serpentine transmembrane antigens expressed in human cancers and uses thereof |
US7037667B1 (en) | 1998-06-01 | 2006-05-02 | Agensys, Inc. | Tumor antigen useful in diagnosis and therapy of prostate and colon cancer |
US6833438B1 (en) | 1999-06-01 | 2004-12-21 | Agensys, Inc. | Serpentine transmembrane antigens expressed in human cancers and uses thereof |
US20060052321A1 (en) | 2002-04-05 | 2006-03-09 | Raitano Arthur B | Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer |
US20040141975A1 (en) | 1998-06-01 | 2004-07-22 | Raitano Arthur B. | Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer |
ES2329851T3 (es) | 1998-06-01 | 2009-12-01 | Agensys, Inc. | Nuevos antigenos transmembranables expresados en canceres humano y utilizacion de los mismos. |
WO2002016429A2 (en) * | 2000-08-24 | 2002-02-28 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
US7189565B2 (en) | 2001-03-23 | 2007-03-13 | Fahri Saatcioglu | Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods |
US7611892B2 (en) | 2000-03-24 | 2009-11-03 | President And Fellows Of Harvard College | Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods |
AU2002336446B2 (en) * | 2001-09-06 | 2008-03-06 | Agensys, Inc. | Nucleic acid and corresponding protein entitled STEAP-1 useful in treatment and detection of cancer |
US7494646B2 (en) | 2001-09-06 | 2009-02-24 | Agensys, Inc. | Antibodies and molecules derived therefrom that bind to STEAP-1 proteins |
WO2003087306A2 (en) * | 2002-04-05 | 2003-10-23 | Agensys, Inc. | Nucleic acid and corresponding protein entitled 98p4b6 useful in treatment and detection of cancer |
WO2004016643A2 (en) * | 2002-08-16 | 2004-02-26 | Yeda Research And Development Co. Ltd. | Tumor associated antigen, peptides thereof, and use of same as anti-tumor vaccines |
JP5840351B2 (ja) | 2002-09-06 | 2016-01-06 | アジェンシス,インコーポレイテッド | 癌の処置および検出において有用な98p4b6と称される、核酸および対応タンパク質 |
WO2004078146A2 (en) * | 2003-03-05 | 2004-09-16 | Innexus Biotechnology International Limited | Trans-membrane-antibody induced inhibition of apoptosis |
KR101520209B1 (ko) | 2003-11-06 | 2015-05-13 | 시애틀 지네틱스, 인크. | 리간드에 접합될 수 있는 모노메틸발린 화합물 |
ES2443996T3 (es) | 2004-04-22 | 2014-02-21 | Agensys, Inc. | Anticuerpos y moléculas derivadas de los mismos que se unen a proteínas STEAP-1 |
AU2005246090A1 (en) * | 2005-02-22 | 2005-12-01 | Biomedisinsk Innovasjon As | STAMP2 nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods |
JP4191189B2 (ja) | 2005-12-08 | 2008-12-03 | 康生 梅津 | がん関連遺伝子活性化能を有するペプチド |
US8586006B2 (en) | 2006-08-09 | 2013-11-19 | Institute For Systems Biology | Organ-specific proteins and methods of their use |
SI2502938T1 (sl) | 2006-10-27 | 2015-05-29 | Genentech, Inc. | Protitelesa in imunokonjugati in njihove uporabe |
JP5394246B2 (ja) * | 2007-03-30 | 2014-01-22 | ジェネンテック, インコーポレイテッド | 抗体及びイムノコンジュゲートとこれらの使用方法 |
TW200918089A (en) | 2007-07-16 | 2009-05-01 | Genentech Inc | Humanized anti-CD79b antibodies and immunoconjugates and methods of use |
JP5469600B2 (ja) | 2007-07-16 | 2014-04-16 | ジェネンテック, インコーポレイテッド | 抗CD79b抗体及びイムノコンジュゲートとその使用方法 |
WO2009046739A1 (en) * | 2007-10-09 | 2009-04-16 | Curevac Gmbh | Composition for treating prostate cancer (pca) |
SI2657253T1 (sl) | 2008-01-31 | 2017-10-30 | Genentech, Inc. | Protitelesa proti CD79b in imunokonjugati in postopki za uporabo |
WO2010037408A1 (en) | 2008-09-30 | 2010-04-08 | Curevac Gmbh | Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof |
WO2014165818A2 (en) | 2013-04-05 | 2014-10-09 | T Cell Therapeutics, Inc. | Compositions and methods for preventing and treating prostate cancer |
PL3262071T3 (pl) | 2014-09-23 | 2020-08-10 | F. Hoffmann-La Roche Ag | Sposób stosowania immunokoniugatów anty-CD79b |
EP4183806A3 (de) | 2014-11-12 | 2023-08-02 | Seagen Inc. | Glycaninteragierende verbindungen und verfahren zur verwendung |
US9879087B2 (en) | 2014-11-12 | 2018-01-30 | Siamab Therapeutics, Inc. | Glycan-interacting compounds and methods of use |
IL258768B2 (en) | 2015-11-12 | 2023-11-01 | Siamab Therapeutics Inc | Compounds interacting with glycans and methods of use |
KR102520731B1 (ko) * | 2016-09-23 | 2023-04-14 | 리제너론 파아마슈티컬스, 인크. | 항-steap2 항체, 항체-약물 컨쥬게이트, 및 steap2 및 cd3에 결합하는 이중특이적 항원-결합 분자, 및 이의 용도 |
EP3541847A4 (de) | 2016-11-17 | 2020-07-08 | Seattle Genetics, Inc. | Glycaninteragierende verbindungen und verfahren zur verwendung |
MA47812A (fr) | 2017-03-03 | 2021-04-14 | Seagen Inc | Composés interagissant avec le glycane et méthodes d'utilisation |
BR112019018767A2 (pt) | 2017-04-03 | 2020-05-05 | Hoffmann La Roche | anticorpos, molécula de ligação ao antígeno biespecífica, um ou mais polinucleotídeos isolados, um ou mais vetores, célula hospedeira, método para produzir um anticorpo, composição farmacêutica, usos, método para tratar uma doença em um indivíduo e invenção |
WO2019125184A1 (en) | 2017-12-19 | 2019-06-27 | Auckland Uniservices Limited | Use of biomarker in cancer therapy |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5489525A (en) * | 1992-10-08 | 1996-02-06 | The United States Of America As Represented By The Department Of Health And Human Services | Monoclonal antibodies to prostate cells |
US5919652A (en) | 1994-11-09 | 1999-07-06 | The Regents Of The University Of California | Nucleic acid molecules comprising the prostate specific antigen (PSA) promoter and uses thereof |
WO1998018489A1 (en) * | 1996-10-30 | 1998-05-07 | The Uab Research Foundation | Enhancement of tumor cell chemosensitivity and radiosensitivity using single chain intracellular antibodies |
US6048970A (en) * | 1998-05-22 | 2000-04-11 | Incyte Pharmaceuticals, Inc. | Prostate growth-associated membrane proteins |
ES2329851T3 (es) * | 1998-06-01 | 2009-12-01 | Agensys, Inc. | Nuevos antigenos transmembranables expresados en canceres humano y utilizacion de los mismos. |
EP1140970A4 (de) * | 1998-12-17 | 2003-10-22 | Human Genome Sciences Inc | 47 menschliche sekretierte proteine |
US20020015950A1 (en) * | 1999-07-07 | 2002-02-07 | Karen Anne Jones | Atherosclerosis-associated genes |
WO2001012662A2 (en) * | 1999-08-17 | 2001-02-22 | Incyte Genomics, Inc. | Membrane associated proteins |
-
2000
- 2000-12-06 IL IL15001800A patent/IL150018A0/xx unknown
- 2000-12-06 PT PT00983938T patent/PT1244705E/pt unknown
- 2000-12-06 ES ES00983938T patent/ES2340249T3/es not_active Expired - Lifetime
- 2000-12-06 AU AU20629/01A patent/AU775366B2/en not_active Expired
- 2000-12-06 CA CA2395053A patent/CA2395053C/en not_active Expired - Lifetime
- 2000-12-06 EP EP05014435A patent/EP1642909A3/de not_active Withdrawn
- 2000-12-06 AT AT00983938T patent/ATE456578T1/de active
- 2000-12-06 EP EP00983938A patent/EP1244705B1/de not_active Expired - Lifetime
- 2000-12-06 JP JP2001541031A patent/JP4827357B2/ja not_active Expired - Lifetime
- 2000-12-06 DE DE60043784T patent/DE60043784D1/de not_active Expired - Lifetime
- 2000-12-06 DK DK00983938.2T patent/DK1244705T3/da active
- 2000-12-06 WO PCT/US2000/033040 patent/WO2001040276A2/en active Application Filing
-
2002
- 2002-06-04 IL IL150018A patent/IL150018A/en active IP Right Grant
-
2004
- 2004-10-29 AU AU2004224964A patent/AU2004224964B2/en not_active Expired
-
2005
- 2005-12-19 JP JP2005365540A patent/JP2006204290A/ja not_active Withdrawn
-
2009
- 2009-06-10 IL IL199275A patent/IL199275A0/en active IP Right Grant
-
2010
- 2010-04-26 CY CY20101100373T patent/CY1111034T1/el unknown
- 2010-09-22 JP JP2010212334A patent/JP2011062201A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2004224964B2 (en) | 2008-10-02 |
JP2006204290A (ja) | 2006-08-10 |
ATE456578T1 (de) | 2010-02-15 |
PT1244705E (pt) | 2010-05-04 |
JP2011062201A (ja) | 2011-03-31 |
AU775366B2 (en) | 2004-07-29 |
ES2340249T3 (es) | 2010-06-01 |
EP1642909A2 (de) | 2006-04-05 |
DK1244705T3 (da) | 2010-05-31 |
CA2395053A1 (en) | 2001-06-07 |
EP1244705A2 (de) | 2002-10-02 |
EP1642909A3 (de) | 2006-04-12 |
CY1111034T1 (el) | 2015-08-05 |
IL199275A0 (en) | 2011-07-31 |
EP1244705B1 (de) | 2010-01-27 |
IL150018A (en) | 2011-04-28 |
IL150018A0 (en) | 2002-12-01 |
AU2062901A (en) | 2001-06-12 |
AU2004224964A1 (en) | 2004-11-25 |
JP2003517306A (ja) | 2003-05-27 |
WO2001040276A2 (en) | 2001-06-07 |
WO2001040276A3 (en) | 2002-01-10 |
JP4827357B2 (ja) | 2011-11-30 |
CA2395053C (en) | 2012-05-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |