JP4821606B2 - 効率的にＬ−グルタミン酸を生産するためのプロモーター変異による細菌のｓｕｃＡＢ発現の最適化 - Google Patents
効率的にＬ−グルタミン酸を生産するためのプロモーター変異による細菌のｓｕｃＡＢ発現の最適化 Download PDFInfo
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2003106551/15A RU2003106551A (ru) | 2003-03-12 | Способ получения l-аминокислот с использованием бактерий с оптимизированным уровнем генной экспрессии | |
| RU2003106551 | 2003-03-12 | ||
| RU2003136412 | 2003-12-18 | ||
| RU2003136412/13A RU2268305C2 (ru) | 2003-12-18 | 2003-12-18 | Способ получения l-аминокислот с использованием бактерий с оптимизированным уровнем генной экспрессии |
| PCT/JP2004/003377 WO2004080386A2 (en) | 2003-03-12 | 2004-03-12 | Optimization of bacterial sucab expression by promoter mutagenesis for efficient l-glutamic acid production |
Publications (3)
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| JP2006519613A JP2006519613A (ja) | 2006-08-31 |
| JP2006519613A5 JP2006519613A5 (https=) | 2007-05-10 |
| JP4821606B2 true JP4821606B2 (ja) | 2011-11-24 |
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| JP2006507666A Expired - Fee Related JP4821606B2 (ja) | 2003-03-12 | 2004-03-12 | 効率的にＬ−グルタミン酸を生産するためのプロモーター変異による細菌のｓｕｃＡＢ発現の最適化 |
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| US (1) | US7604979B2 (https=) |
| EP (1) | EP1604023A2 (https=) |
| JP (1) | JP4821606B2 (https=) |
| BR (1) | BRPI0407966A (https=) |
| WO (1) | WO2004080386A2 (https=) |
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| RU2229513C2 (ru) * | 2001-11-23 | 2004-05-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Способ получения l-аминокислот, штамм escherichia coli - продуцент l-аминокислоты (варианты) |
| RU2004124226A (ru) | 2004-08-10 | 2006-01-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | Использование фосфокетолазы для продукции полезных метаболитов |
| US7915018B2 (en) * | 2004-10-22 | 2011-03-29 | Ajinomoto Co., Inc. | Method for producing L-amino acids using bacteria of the Enterobacteriaceae family |
| WO2006088235A1 (en) | 2005-02-18 | 2006-08-24 | Ajinomoto Co., Inc. | A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family |
| DE602006015302D1 (de) | 2005-05-16 | 2010-08-19 | Ajinomoto Kk | Verfahren zur herstellung einer l-aminosäure unter verwendung eines bakteriums der familie enterobacteriaceae mit abgeschwächter expression des kefb-gens |
| EP1907529A1 (en) * | 2005-07-25 | 2008-04-09 | Ajinomoto Co., Inc. | A METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF THE cpxR GENE |
| DE602006004893D1 (de) * | 2005-08-09 | 2009-03-05 | Ajinomoto Kk | VERFAHREN ZUR HERSTELLUNG EINER L-AMINOSÄURE UNTER VERWENDUNG EINES BAKTERIUMS DER FAMILIE ENTEROBACTERIACEAE MIT ABGESCHWÄCHTER EXPRESSION DES ybiV-GENS |
| JP2009095237A (ja) * | 2006-02-02 | 2009-05-07 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| EP2351830B1 (en) * | 2006-03-23 | 2014-04-23 | Ajinomoto Co., Inc. | A method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with attenuated expression of a gene coding for small RNA |
| WO2007119890A1 (en) | 2006-04-18 | 2007-10-25 | Ajinomoto Co., Inc. | A METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF THE sfmACDFH-fimZ CLUSTER OR THE fimZ GENE |
| RU2006129690A (ru) | 2006-08-16 | 2008-02-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНА ydiN, ГЕНА ydiB ИЛИ ИХ КОМБИНАЦИИ |
| JP2010041920A (ja) * | 2006-12-19 | 2010-02-25 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| JP5837747B2 (ja) | 2007-05-17 | 2015-12-24 | ベーリンガー インゲルハイム エルツェーファウ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト | 組換えタンパク質を工業規模で製造する方法 |
| RU2396336C2 (ru) | 2007-09-27 | 2010-08-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПОЛУЧЕНИЯ АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia |
| RU2008105793A (ru) * | 2008-02-19 | 2009-08-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | Способ конструирования оперонов, содержащих трансляционно сопряженные гены, бактерия, содержащая такой оперон, способ продукции полезного метаболита и способ мониторинга экспрессии гена |
| RU2010101135A (ru) | 2010-01-15 | 2011-07-20 | Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) (RU) | Бактерия семейства enterobacteriaceae - продуцент l-аспартата или метаболитов, производных l-аспартата, и способ получения l-аспартата или метаболитов, производных l-аспартата |
| KR101547651B1 (ko) * | 2014-06-03 | 2015-08-26 | 씨제이제일제당 주식회사 | O-숙시닐호모세린 또는 숙신산의 생산능을 갖는 미생물 및 이를 이용한 숙신산 또는 o-숙시닐호모세린의 생산 방법 |
| JP7447810B2 (ja) | 2018-05-23 | 2024-03-12 | 味の素株式会社 | 腸内細菌科を用いたトリペプチドγ－ＧＬＵ－ＶＡＬ－ＧＬＹの製造方法 |
| CN110218691A (zh) * | 2019-05-21 | 2019-09-10 | 南京工业大学 | 一株合成l-天冬酰胺的基因工程菌及其构建方法与应用 |
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| WO1995034672A1 (en) * | 1994-06-14 | 1995-12-21 | Ajinomoto Co., Inc. | α-KETOGLUTARIC DEHYDROGENASE GENE |
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|---|---|---|---|---|
| BR9203053A (pt) * | 1991-08-07 | 1993-03-30 | Ajinomoto Kk | Processo para produzir acido l-glutamico pro fermentacao |
| JP3880636B2 (ja) | 1994-01-10 | 2007-02-14 | 味の素株式会社 | 発酵法によるｌ−グルタミン酸の製造法 |
| JPH09285294A (ja) | 1996-04-23 | 1997-11-04 | Ajinomoto Co Inc | 発酵法によるｌ−グルタミン酸の製造法 |
| EP2034021A1 (en) * | 1996-08-23 | 2009-03-11 | Peter Ruhdal Jensen | Artificial promoter libraries for selected organisms and promoters derived from such libraries |
| RU2212447C2 (ru) | 2000-04-26 | 2003-09-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Штамм escherichia coli - продуцент аминокислоты (варианты) и способ получения аминокислот (варианты) |
| EP1407028B1 (en) * | 2001-07-18 | 2009-06-24 | Evonik Degussa GmbH | Process for the preparation of l-threonine using strains of the enterobacteriaceae family which contain enhanced suca and sucb genes |
| RU2229513C2 (ru) | 2001-11-23 | 2004-05-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Способ получения l-аминокислот, штамм escherichia coli - продуцент l-аминокислоты (варианты) |
| RU2245919C2 (ru) | 2002-09-06 | 2005-02-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Способ получения l-аминокислоты, штамм escherichia coli tdh7δ mlc::cat/pprt614-продуцент l-треонина |
| US20050191684A1 (en) | 2004-02-25 | 2005-09-01 | Zimenkov Danila V. | Method for producing L-amino acids |
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- 2004-03-12 BR BRPI0407966-3A patent/BRPI0407966A/pt not_active Application Discontinuation
- 2004-03-12 EP EP04720229A patent/EP1604023A2/en not_active Withdrawn
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995034672A1 (en) * | 1994-06-14 | 1995-12-21 | Ajinomoto Co., Inc. | α-KETOGLUTARIC DEHYDROGENASE GENE |
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| EP1604023A2 (en) | 2005-12-14 |
| BRPI0407966A (pt) | 2006-03-07 |
| WO2004080386A3 (en) | 2004-12-02 |
| WO2004080386A2 (en) | 2004-09-23 |
| US20060063240A1 (en) | 2006-03-23 |
| US7604979B2 (en) | 2009-10-20 |
| JP2006519613A (ja) | 2006-08-31 |
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