JP4817387B2 - 流体薬剤送達装置 - Google Patents
流体薬剤送達装置 Download PDFInfo
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- JP4817387B2 JP4817387B2 JP2006527018A JP2006527018A JP4817387B2 JP 4817387 B2 JP4817387 B2 JP 4817387B2 JP 2006527018 A JP2006527018 A JP 2006527018A JP 2006527018 A JP2006527018 A JP 2006527018A JP 4817387 B2 JP4817387 B2 JP 4817387B2
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- Prior art keywords
- fluid
- delivery device
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- patient
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M35/00—Devices for applying media, e.g. remedies, on the human body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00544—Plasters form or structure
- A61F2013/00646—Medication patches, e.g. transcutaneous
- A61F2013/00651—Medication patches, e.g. transcutaneous tapered, bevelled or chamfered
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- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Materials Engineering (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Materials For Medical Uses (AREA)
Description
[発明の分野]
本発明は、概して流体送達装置に関し、より詳細には、患者の皮膚表面範囲に流体薬剤を供する流体薬剤送達装置に関する。
経皮パッチは、流体薬剤等の薬学的物質を患者の皮膚を通過させることにより、そのような流体を患者に送達する機構として既知である。経皮パッチは、例えば、ホルモン補充療法及び禁煙等の治療に使用されている。経皮パッチの種類のうち1つは、補充不可な(unreplenishable)薬学的物質の供給を含む。このパッチは、パッチを皮膚に接着しやすくするための、皮膚接触接着層を有する。一般に、そのような経皮パッチは、物質が患者に送達される期間、皮膚の適した範囲に接着される。
少なくとも1つの流体半透過層を含む。
ら患者の皮膚へ流れる流体の速度及び分布を制御するために、他の実施形態において、拡散シート20は、多孔不透過シート、コイル状バネ、コイル状ワイヤ/コード、あるいは別の類似装置により補強又は置換されてもよい。好ましい多孔質膜材料の1つは、Del Star Technologies, Inc製の商品名DELNETという開口部を備えたフィルム固体である。
お、流体25は、不透過シート18又は拡散シート20により圧力をかけられることなく、拡散シート20を通じて拡散することができる。望ましくは、拡散シート20は流体25の流速に影響を及ぼし、そして流体25を皮膚に均一に分布させる。具体的には、好適な構成において、拡散シート20の孔の大きさが流体25の装置10からの流速を決定する。
る特定のシートに依存して、流体送達装置90の操作は、装置10、装置30、又は装置40の操作と実質的に同様である。
04及び下部層106の間の外周シール108内に固定されてもよい。
、実質的に互いに平行に配列されている。
って流れることができる。接着片200は、流体25が患者に吸収されている間、流体送達装置190、224の外周202を患者の皮膚に固定する。
及び形状が定められてもよい。
Companyにより市販されている。この特定の材料はまた、創傷流体と接触するとゲル化又は膨潤して、患者と装置300との間のデッドスペース(dead space)を減少させる特徴も有する。抗菌性物質層330は、ゲル化材料内の細菌も閉じ込める。さらに、イオン化銀は、細菌及び他の病原を殺傷する。したがって、抗菌性物質層330の抗菌性により、流体送達装置300を、かなりの長時間にわたって取り外すことなく使用できる。したがって、装置300の真下の範囲を清潔にする目的での、不便でしばしば痛みを伴う装置300の取り外しが、治療過程の間、減少するか排除される。別の構成において、拡散シート320はイオン化銀で含浸されていてもよく、且つ追加層330が省略されてもよい。さらに、他の抗菌性物質が用いられてもよい。
と第二チャンバ336とに分割する。第一チャンバ334は、拡散シート320の上部表面と不透過シート318の下部表面との間に確定され、そして第二チャンバ336は、拡散シート320の下部表面と不透過下部シート332との上部表面の間に確定される。下部不透過シート332は、好ましくは、送達装置430のリザーバから患者の皮膚への流体通過を可能にする、1つ又は複数の通路335を含む。
Claims (7)
- 流体薬剤送達装置であって、
流体不透過層と、
流体半透過層と、
流体注入口とを含み、
前記流体半透過層及び前記流体不透過層は共同してそれらの間にある空間を確定し、該空間は前記送達装置の流体リザーバを確定し、前記流体半透過層及び前記流体不透過層はそれらの間に連続シールを有して前記流体リザーバの外周を確定し、
前記流体リザーバの外周内に少なくとも1つの内部壁をさらに含み、該内部壁は該流体リザーバ内に相互接続した複数の領域を形成するように構成され、
前記流体注入口は、流体リザーバと連絡し、流体が前記流体リザーバに入れるように形状が定められた弁を含み、前記流体注入口は前記送達装置が流体供給と選択的に接続することを可能にし、
前記弁は注入口通路を確定し、
流体が前記流体リザーバに入れるように形状が定められ、且つ流体が前記注入口通路を通じて該流体リザーバから出ることを防ぐ一方向弁を含み、
流体は、該流体により付与される圧力に応答して前記流体半透過層を通って拡散可能である、流体薬剤送達装置。 - 前記流体半透過層は、孔の大きさが0.25ミクロン未満である多孔質膜を含む、請求項1に記載の送達装置。
- 前記少なくとも1つの内部壁は、前記流体不透過層と前記流体半透過層との間のシールにより確定される、請求項1または2に記載の送達装置。
- 前記流体半透過層は、ポリエチレン、ポリスルホン、ポリエーテルスルホン、ポリビニリデンジフルオリド、ポリカーボネート、ナイロン、高密度ポリエチレン、及びポリテトラフルオロエチレンのうち1つから選択される材料を含む、請求項1〜3のいずれか一項に記載の送達装置。
- 流体は、流体圧力の外部源により流体にかけられる圧力に応答して、前記流体半透過層
を通って拡散可能である、請求項1〜4の何れか一項に記載の送達装置。 - 前記流体注入口は、送達装置がルアーコネクタを用いて流体の供給と選択的に接続することを可能にしている、請求項1〜5の何れか一項に記載の送達装置。
- 上記流体薬剤送達装置が制御された流速で流体を患者に連続的に送達するように、管及び/又は外部流体源が、上記弁に接続されたままであることを特徴とする、請求項1〜6の何れか一項に記載の送達装置。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/663,362 US7470266B2 (en) | 2003-09-16 | 2003-09-16 | Fluid medication delivery device |
US10/663,362 | 2003-09-16 | ||
PCT/US2004/030316 WO2005028018A1 (en) | 2003-09-16 | 2004-09-16 | Fluid medication delivery device |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010141039A Division JP5017426B2 (ja) | 2003-09-16 | 2010-06-21 | 流体薬剤送達装置 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2007505702A JP2007505702A (ja) | 2007-03-15 |
JP2007505702A5 JP2007505702A5 (ja) | 2007-07-26 |
JP4817387B2 true JP4817387B2 (ja) | 2011-11-16 |
Family
ID=34274361
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006527018A Expired - Fee Related JP4817387B2 (ja) | 2003-09-16 | 2004-09-16 | 流体薬剤送達装置 |
JP2010141039A Expired - Fee Related JP5017426B2 (ja) | 2003-09-16 | 2010-06-21 | 流体薬剤送達装置 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010141039A Expired - Fee Related JP5017426B2 (ja) | 2003-09-16 | 2010-06-21 | 流体薬剤送達装置 |
Country Status (6)
Country | Link |
---|---|
US (5) | US7470266B2 (ja) |
EP (2) | EP2407204B1 (ja) |
JP (2) | JP4817387B2 (ja) |
AU (1) | AU2004273898B2 (ja) |
CA (1) | CA2538527C (ja) |
WO (1) | WO2005028018A1 (ja) |
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- 2004-09-16 US US10/942,735 patent/US7771413B2/en active Active
- 2004-09-16 EP EP11008213.8A patent/EP2407204B1/en not_active Not-in-force
- 2004-09-16 JP JP2006527018A patent/JP4817387B2/ja not_active Expired - Fee Related
- 2004-09-16 AU AU2004273898A patent/AU2004273898B2/en not_active Ceased
- 2004-09-16 CA CA2538527A patent/CA2538527C/en not_active Expired - Fee Related
- 2004-09-16 EP EP04788782.3A patent/EP1673133B1/en not_active Not-in-force
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2008
- 2008-12-23 US US12/343,397 patent/US7854732B2/en not_active Expired - Lifetime
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2010
- 2010-06-21 JP JP2010141039A patent/JP5017426B2/ja not_active Expired - Fee Related
- 2010-08-10 US US12/853,774 patent/US8323266B2/en not_active Expired - Lifetime
- 2010-08-10 US US12/853,787 patent/US8241269B2/en not_active Expired - Lifetime
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Also Published As
Publication number | Publication date |
---|---|
AU2004273898A1 (en) | 2005-03-31 |
US20100305521A1 (en) | 2010-12-02 |
US20090105667A1 (en) | 2009-04-23 |
JP2007505702A (ja) | 2007-03-15 |
US20050106225A1 (en) | 2005-05-19 |
US8241269B2 (en) | 2012-08-14 |
JP5017426B2 (ja) | 2012-09-05 |
EP2407204B1 (en) | 2014-06-18 |
US20100305522A1 (en) | 2010-12-02 |
US7470266B2 (en) | 2008-12-30 |
WO2005028018A1 (en) | 2005-03-31 |
US8323266B2 (en) | 2012-12-04 |
US7854732B2 (en) | 2010-12-21 |
EP2407204A1 (en) | 2012-01-18 |
AU2004273898B2 (en) | 2011-09-01 |
US7771413B2 (en) | 2010-08-10 |
EP1673133B1 (en) | 2014-11-12 |
CA2538527C (en) | 2014-07-22 |
EP1673133A1 (en) | 2006-06-28 |
CA2538527A1 (en) | 2005-03-31 |
JP2010214136A (ja) | 2010-09-30 |
US20050058711A1 (en) | 2005-03-17 |
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