JP4813377B2 - 耐酸化性の高結晶性架橋ポリエチレン - Google Patents

耐酸化性の高結晶性架橋ポリエチレン Download PDF

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Publication number
JP4813377B2
JP4813377B2 JP2006552224A JP2006552224A JP4813377B2 JP 4813377 B2 JP4813377 B2 JP 4813377B2 JP 2006552224 A JP2006552224 A JP 2006552224A JP 2006552224 A JP2006552224 A JP 2006552224A JP 4813377 B2 JP4813377 B2 JP 4813377B2
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mpa
blend
pressure
temperature
highly crystalline
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JP2007520620A (ja
JP2007520620A5 (https=
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オルフン、ケイ．ムラトグル
エブル、オラル
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General Hospital Corp
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General Hospital Corp
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
    • B29C43/003—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor characterised by the choice of material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C71/00—After-treatment of articles without altering their shape; Apparatus therefor
    • B29C71/0009—After-treatment of articles without altering their shape; Apparatus therefor using liquids, e.g. solvents, swelling agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C71/00—After-treatment of articles without altering their shape; Apparatus therefor
    • B29C71/02—Thermal after-treatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C71/00—After-treatment of articles without altering their shape; Apparatus therefor
    • B29C71/04—After-treatment of articles without altering their shape; Apparatus therefor by wave energy or particle radiation, e.g. for curing or vulcanising preformed articles
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/28—Treatment by wave energy or particle radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B29C35/0866—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using particle radiation
    • B29C2035/0877—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using particle radiation using electron radiation, e.g. beta-rays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C71/00—After-treatment of articles without altering their shape; Apparatus therefor
    • B29C71/0009—After-treatment of articles without altering their shape; Apparatus therefor using liquids, e.g. solvents, swelling agents
    • B29C2071/0027—Removing undesirable residual components, e.g. solvents, unreacted monomers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C71/00—After-treatment of articles without altering their shape; Apparatus therefor
    • B29C71/02—Thermal after-treatment
    • B29C2071/022—Annealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
    • B29K2023/04—Polymers of ethylene
    • B29K2023/06—PE, i.e. polyethylene
    • B29K2023/0658—PE, i.e. polyethylene characterised by its molecular weight
    • B29K2023/0683—UHMWPE, i.e. ultra high molecular weight polyethylene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
    • B29K2023/04—Polymers of ethylene
    • B29K2023/08—Copolymers of ethylene
    • B29K2023/083—EVA, i.e. ethylene vinyl acetate copolymer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/7532—Artificial members, protheses
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2323/00—Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers
    • C08J2323/02—Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers not modified by chemical after treatment
    • C08J2323/04—Homopolymers or copolymers of ethene
    • C08J2323/06—Polyethene
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/4998—Combined manufacture including applying or shaping of fluent material

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Thermal Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
JP2006552224A 2004-02-03 2005-02-03 耐酸化性の高結晶性架橋ポリエチレン Expired - Lifetime JP4813377B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US54107304P 2004-02-03 2004-02-03
US60/541,073 2004-02-03
PCT/US2005/003305 WO2005074619A2 (en) 2004-02-03 2005-02-03 Highly crystalline cross-linked oxidation-resistant polyethylene

Publications (3)

Publication Number Publication Date
JP2007520620A JP2007520620A (ja) 2007-07-26
JP2007520620A5 JP2007520620A5 (https=) 2008-02-28
JP4813377B2 true JP4813377B2 (ja) 2011-11-09

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Country Link
US (2) US8426486B2 (https=)
EP (2) EP1720485B8 (https=)
JP (1) JP4813377B2 (https=)
AU (2) AU2005209868B8 (https=)
CA (1) CA2554777C (https=)
WO (1) WO2005074619A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010000221A (ja) * 2008-06-20 2010-01-07 Nakashima Medical Co Ltd 人工関節用摺動部材の成形方法及びこの方法によって成形された人工関節用摺動部材

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8845672B2 (en) 2002-05-09 2014-09-30 Reshape Medical, Inc. Balloon system and methods for treating obesity
EP1686932B1 (en) 2003-06-27 2010-01-06 ABS Corporation System for ankle arthroplasty
EP1720485B8 (en) * 2004-02-03 2016-10-12 The General Hospital Corporation Highly crystalline cross-linked oxidation-resistant polyethylene
EP1750614B1 (en) * 2004-05-11 2017-09-27 The General Hospital Corporation Methods for making oxidation resistant polymeric material
US8262976B2 (en) * 2004-10-07 2012-09-11 Biomet Manufacturing Corp. Solid state deformation processing of crosslinked high molecular weight polymeric materials
US7344672B2 (en) * 2004-10-07 2008-03-18 Biomet Manufacturing Corp. Solid state deformation processing of crosslinked high molecular weight polymeric materials
US7462318B2 (en) 2004-10-07 2008-12-09 Biomet Manufacturing Corp. Crosslinked polymeric material with enhanced strength and process for manufacturing
EP2277560B1 (en) 2005-08-18 2013-10-09 Zimmer GmbH Ultra high molecular weight polyethylene articles and methods od forming ultra high molecular weight polyethylene articles
EP2441781A1 (en) 2005-08-22 2012-04-18 The General Hospital Corporation d/b/a Massachusetts General Hospital Highly crystalline polyethylene
AU2013200195B2 (en) * 2005-08-22 2014-12-04 The General Hospital Corporation Highly crystalline polyethylene
ATE529464T1 (de) * 2005-08-22 2011-11-15 Gen Hospital Corp Dba Massachusetts General Hospital Oxidationsbeständiges homogenisiertes polymermaterial
US20070100368A1 (en) 2005-10-31 2007-05-03 Quijano Rodolfo C Intragastric space filler
US7635725B2 (en) 2006-02-21 2009-12-22 The Brigham And Women's Hospital, Inc. Crosslinked polymers
US7998404B2 (en) 2006-07-13 2011-08-16 Advanced Cardiovascular Systems, Inc. Reduced temperature sterilization of stents
EP2083981B1 (en) * 2006-10-30 2021-10-06 Smith & Nephew Orthopaedics AG Processes comprising crosslinking polyethylene or using crosslinked polyethylene
CN103223702B (zh) * 2006-10-30 2018-06-22 施乐辉骨科用品股份公司 包括交联聚乙烯或使用已交联聚乙烯的方法
CA2679274C (en) * 2007-03-02 2018-02-20 The General Hospital Corporation Cross-linking of antioxidant-containing polymers
EP2150285B1 (en) * 2007-04-10 2012-02-08 Zimmer, Inc. An antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
US8664290B2 (en) 2007-04-10 2014-03-04 Zimmer, Inc. Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
US8142469B2 (en) 2007-06-25 2012-03-27 Reshape Medical, Inc. Gastric space filler device, delivery system, and related methods
US8641959B2 (en) 2007-07-27 2014-02-04 Biomet Manufacturing, Llc Antioxidant doping of crosslinked polymers to form non-eluting bearing components
WO2009032909A2 (en) 2007-09-04 2009-03-12 Smith & Nephew Orthopaedics Ag Ultra high molecular weight polyethylene for bearing surfaces
CA2712559C (en) * 2008-01-30 2015-03-31 Zimmer, Inc. Orthopedic component of low stiffness
RU2495054C2 (ru) 2008-05-13 2013-10-10 Смит Энд Нефью Ортопедикс Аг Устойчивый к окислению высокосшитый сверхвысокомолекулярный полиэтилен
GB0812890D0 (en) * 2008-07-11 2008-08-20 Smith & Nephew Orthopaedics Ag Compositions and methods of making compositions
DE102008053793A1 (de) 2008-10-21 2010-04-22 Aesculap Ag Antioxidativ wirksames, synthetisches Polymermaterial
WO2010057644A1 (en) * 2008-11-20 2010-05-27 Zimmer Gmbh Polyethylene materials
US8933145B2 (en) 2009-02-20 2015-01-13 The General Hospital Corporation High temperature melting
US9174031B2 (en) 2009-03-13 2015-11-03 Reshape Medical, Inc. Device and method for deflation and removal of implantable and inflatable devices
CA2757547A1 (en) * 2009-04-03 2010-10-07 Reshape Medical, Inc. Improved intragastric space fillers and methods of manufacturing including in vitro testing
US20120070600A1 (en) * 2009-05-20 2012-03-22 Muratoglu Orhun K Metods of preventing oxidation
JP4806717B2 (ja) * 2009-06-25 2011-11-02 株式会社沖データ 画像処理システム
EP2456507A4 (en) 2009-07-22 2013-07-03 Reshape Medical Inc RETENTION MECHANISMS FOR IMPLANTABLE MEDICAL DEVICES
WO2011011743A2 (en) 2009-07-23 2011-01-27 Reshape Medical, Inc. Deflation and removal of implantable medical devices
EP2456487A4 (en) 2009-07-23 2017-05-17 ReShape Medical, Inc. Inflation and deflation mechanisms for inflatable medical devices
WO2011038270A2 (en) 2009-09-24 2011-03-31 Reshape Medical, Inc. Normalization and stabilization of balloon surfaces for deflation
US20110111359A1 (en) * 2009-11-09 2011-05-12 Weathers Jr Arthur Kitchings Dental extracted tooth replacement method
GB0922339D0 (en) 2009-12-21 2010-02-03 Mcminn Derek J W Acetabular cup prothesis and introducer thereof
EP2533846B1 (en) 2010-02-08 2018-08-22 ReShape Medical LLC Materials and methods for improved intragastric balloon devices
EP2533845A4 (en) 2010-02-08 2016-04-06 Reshape Medical Inc IMPROVED AND REINFORCED EXTRACTION METHOD AND MECHANISMS FOR INTRAGASTRAL DEVICES
EP2539011A4 (en) 2010-02-25 2014-03-26 Reshape Medical Inc Improved and enhanced explant processes and mechanisms for intragastric devices
WO2011127205A1 (en) 2010-04-06 2011-10-13 Reshape Medical , Inc. Inflation devices for intragastric devices with improved attachment and detachment and associated systems and methods
US8399535B2 (en) 2010-06-10 2013-03-19 Zimmer, Inc. Polymer [[s]] compositions including an antioxidant
CN103003056B (zh) * 2010-07-16 2015-06-17 积水化学工业株式会社 高分子制品及高分子制品的制造方法
US8966868B2 (en) * 2011-05-09 2015-03-03 Abbott Cardiovascular Systems Inc. Methods of stabilizing molecular weight of polymer stents after sterilization
WO2013174782A1 (en) * 2012-05-22 2013-11-28 Total Research & Technology Feluy Process for preparing a polymeric product
US9586370B2 (en) * 2013-08-15 2017-03-07 Biomet Manufacturing, Llc Method for making ultra high molecular weight polyethylene
WO2015050851A1 (en) 2013-10-01 2015-04-09 Zimmer, Inc. Polymer compositions comprising one or more protected antioxidants
JP2016536391A (ja) 2013-10-17 2016-11-24 ザ ジェネラル ホスピタル コーポレイション 過酸化物架橋および高温溶融
WO2015095790A1 (en) * 2013-12-20 2015-06-25 The Brigham And Women's Hospital, Inc. Ductile crosslinked polymers and methods of making the same
US10184031B2 (en) 2014-03-12 2019-01-22 Zimmer, Inc. Melt-stabilized ultra high molecular weight polyethylene and method of making the same
US20150368375A1 (en) 2014-06-24 2015-12-24 Biomet Manufacturing, Llc Methods For Making Crosslinked Ultra High Molecular Weight Polyethylene
CA2969751C (en) 2014-12-03 2020-09-22 Zimmer, Inc. Antioxidant-infused ultra high molecular weight polyethylene
CN107667137A (zh) * 2015-03-25 2018-02-06 捷迈有限公司 熔融稳定的超高分子量聚乙烯
CN108348306B (zh) 2015-11-02 2021-01-15 3M创新有限公司 具有连续形状记忆的正畸器具
EP3373990A1 (en) 2015-11-12 2018-09-19 The General Hospital Corporation Methods of making therapeutic polymeric material
EP3411422A1 (en) 2016-02-05 2018-12-12 The General Hospital Corporation Drug eluting polymer composed of biodegradable polymers applied to surface of medical device
AU2017261160A1 (en) 2016-05-02 2018-11-22 The General Hospital Corporation Implant surfaces for pain control
WO2019046243A2 (en) 2017-08-29 2019-03-07 The General Hospital Corporation UV-INITIATED REACTIONS IN POLYMERIC MATERIALS
US12201734B2 (en) * 2017-10-13 2025-01-21 Edwards Lifesciences Corporation Method for sterilizing heart valves
WO2020118175A1 (en) * 2018-12-07 2020-06-11 Massachusetts Institute Of Technology Irradiated polymers in building materials for concrete forming
US11376128B2 (en) 2018-12-31 2022-07-05 Depuy Ireland Unlimited Company Acetabular orthopaedic prosthesis and method
WO2020172269A1 (en) * 2019-02-20 2020-08-27 Dps Joint Coatings, Llc Lubricious coatings for medical devices
CN110564035A (zh) * 2019-08-02 2019-12-13 浙江晟祺实业有限公司 一种超高分子量聚乙烯复合材料及其制备方法
US11319417B2 (en) 2019-08-16 2022-05-03 Exxonmobil Upstream Research Company Methods of manufacturing highly crosslinked polymer particulate
US12171666B2 (en) 2019-12-10 2024-12-24 Depuy Ireland Unlimited Company Metal reinforced acetabular shell liner
US11628066B2 (en) 2019-12-11 2023-04-18 Depuy Ireland Unlimited Company Ceramic acetabular shell liner with a metal ring having a lead-in surface
US11291549B2 (en) 2019-12-11 2022-04-05 Depuy Ireland Unlimited Company Ceramic acetabular shell liners with augments
DE102021103016A1 (de) 2021-02-09 2022-08-11 Aesculap Ag Verfahren zur Herstellung eines Gleitflächenelements, Gleitflächenelement und Kniegelenkendoprothese
US11970600B2 (en) 2021-03-31 2024-04-30 The General Hospital Corporation Di-cumyl peroxide crosslinking of UHMWPE
US12376964B2 (en) 2021-04-30 2025-08-05 Depuy Ireland Unlimited Company Apparatus and method for locking an acetabular liner to an acetabular cup
US12042389B2 (en) 2021-04-30 2024-07-23 Depuy Ireland Unlimited Company Apparatus and method for installing an acetabular liner on an acetabular cup
DE102021117155A1 (de) 2021-07-02 2023-01-05 Aesculap Ag Verfahren und System zur Herstellung von Formkörpern auf Basis von vernetztem UHMWPE sowie Formkörper auf Basis von vernetztem UHMWPE
CN119842136B (zh) * 2025-03-21 2025-06-13 成都友一包装材料有限公司 一种缠绕膜及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07502290A (ja) * 1991-11-27 1995-03-09 デピユイ・オーソピーデイクス・インコーポレーテツド 超高分子量のリニアポリエチレン，製品および製造方法
WO2003059200A1 (en) * 2002-01-04 2003-07-24 Massachusetts General Hospital A high modulus crosslinked polyethylene with reduced residual free radical concentration prepared below the melt
JP2003530957A (ja) * 2000-04-27 2003-10-21 ザ オーソピーディック ホスピタル 人工関節用の耐酸化性及び耐摩耗性ポリエチレン及び該ポリエチレンの製造方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6371985B1 (en) 1995-03-09 2002-04-16 Robert S. Goldberg Prostheses restrained by immediate attachment while ingrowth proceeds naturally over time
CA2246342C (en) 1996-02-13 2008-04-22 Massachusetts Institute Of Technology Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices
US5879400A (en) 1996-02-13 1999-03-09 Massachusetts Institute Of Technology Melt-irradiated ultra high molecular weight polyethylene prosthetic devices
US5827904A (en) 1996-09-27 1998-10-27 Hahn; David Medical implant composition
US6017975A (en) * 1996-10-02 2000-01-25 Saum; Kenneth Ashley Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance
EP1028760B1 (en) * 1996-10-15 2004-04-14 Orthopaedic Hospital Wear resistant surface-gradient cross-linked polyethylene
FI110063B (fi) 1998-12-11 2002-11-29 Antti Yli-Urpo Uusi bioaktiivinen tuote ja sen käyttö
SE9900519D0 (sv) * 1999-02-17 1999-02-17 Lars Lidgren A method for the preparation of UHMWPE doped with an antioxidant and an implant made thereof
US6620198B2 (en) 1999-10-07 2003-09-16 Exactech, Inc. Composite bearing inserts for total knee joints
US6818172B2 (en) * 2000-09-29 2004-11-16 Depuy Products, Inc. Oriented, cross-linked UHMWPE molding for orthopaedic applications
US20030208278A1 (en) 2000-09-29 2003-11-06 Robert Richard Supercritical fluid treatment of irradiated polyethylene
AU2003245420A1 (en) 2002-06-21 2004-01-06 Massachusetts General Hospital Metal back or mesh crosslinking
AU2004206826B8 (en) 2003-01-16 2009-03-26 Cambridge Polymer Group, Inc. Methods for making oxidation resistant polymeric material
EP1720485B8 (en) 2004-02-03 2016-10-12 The General Hospital Corporation Highly crystalline cross-linked oxidation-resistant polyethylene
EP2441781A1 (en) 2005-08-22 2012-04-18 The General Hospital Corporation d/b/a Massachusetts General Hospital Highly crystalline polyethylene
AU2008207807B2 (en) * 2007-01-25 2013-05-16 Cambridge Polymer Group, Inc. Methods for making oxidation-resistant cross-linked polymeric materials
US8872847B2 (en) 2008-08-28 2014-10-28 Google Inc. Architectures and methods for creating and representing time-dependent imagery
WO2013126592A2 (en) 2012-02-21 2013-08-29 Cameron International Corporation Well tree hub and interface for retrievable processing modules

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07502290A (ja) * 1991-11-27 1995-03-09 デピユイ・オーソピーデイクス・インコーポレーテツド 超高分子量のリニアポリエチレン，製品および製造方法
JP2003530957A (ja) * 2000-04-27 2003-10-21 ザ オーソピーディック ホスピタル 人工関節用の耐酸化性及び耐摩耗性ポリエチレン及び該ポリエチレンの製造方法
WO2003059200A1 (en) * 2002-01-04 2003-07-24 Massachusetts General Hospital A high modulus crosslinked polyethylene with reduced residual free radical concentration prepared below the melt

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010000221A (ja) * 2008-06-20 2010-01-07 Nakashima Medical Co Ltd 人工関節用摺動部材の成形方法及びこの方法によって成形された人工関節用摺動部材

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