JP4782701B2 - 液体クロマトグラフィーのための試料注入システム - Google Patents

液体クロマトグラフィーのための試料注入システム Download PDF

Info

Publication number
JP4782701B2
JP4782701B2 JP2006551418A JP2006551418A JP4782701B2 JP 4782701 B2 JP4782701 B2 JP 4782701B2 JP 2006551418 A JP2006551418 A JP 2006551418A JP 2006551418 A JP2006551418 A JP 2006551418A JP 4782701 B2 JP4782701 B2 JP 4782701B2
Authority
JP
Japan
Prior art keywords
fluid
chamber
valve means
outlet
conduit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2006551418A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007519007A (ja
JP2007519007A5 (enExample
Inventor
ゲルハルト，ジエフ・シー
ジヨージエンソン，ジエームズ・ダブリユ
フアドゲン，キース
Original Assignee
ウオーターズ・テクノロジーズ・コーポレイシヨン
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ウオーターズ・テクノロジーズ・コーポレイシヨン filed Critical ウオーターズ・テクノロジーズ・コーポレイシヨン
Publication of JP2007519007A publication Critical patent/JP2007519007A/ja
Publication of JP2007519007A5 publication Critical patent/JP2007519007A5/ja
Application granted granted Critical
Publication of JP4782701B2 publication Critical patent/JP4782701B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/20—Injection using a sampling valve
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/22—Injection in high pressure liquid systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N2030/382—Flow patterns flow switching in a single column
    • G01N2030/385—Flow patterns flow switching in a single column by switching valves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/36—Control of physical parameters of the fluid carrier in high pressure liquid systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Fluid Mechanics (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
JP2006551418A 2004-01-23 2005-01-18 液体クロマトグラフィーのための試料注入システム Expired - Fee Related JP4782701B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53868304P 2004-01-23 2004-01-23
US60/538,683 2004-01-23
PCT/US2005/002401 WO2005071396A1 (en) 2004-01-23 2005-01-18 A sample injector system for liquid chromatography

Publications (3)

Publication Number Publication Date
JP2007519007A JP2007519007A (ja) 2007-07-12
JP2007519007A5 JP2007519007A5 (enExample) 2008-02-21
JP4782701B2 true JP4782701B2 (ja) 2011-09-28

Family

ID=34807210

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006551418A Expired - Fee Related JP4782701B2 (ja) 2004-01-23 2005-01-18 液体クロマトグラフィーのための試料注入システム

Country Status (5)

Country Link
US (1) US8173070B2 (enExample)
JP (1) JP4782701B2 (enExample)
DE (1) DE112005000128B4 (enExample)
GB (2) GB2426216B (enExample)
WO (1) WO2005071396A1 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008006266B4 (de) 2008-01-25 2011-06-09 Dionex Softron Gmbh Probengeber für die Flüssigkeitschromatographie, insbesondere für die Hochleistungsflüssigkeitschromatographie
US20100224543A1 (en) * 2009-03-05 2010-09-09 Ellis Scott J Connection assembly for ultra high pressure liquid chromatography
US9151734B2 (en) * 2009-03-05 2015-10-06 Idex Health & Science Llc Connection assembly for ultra high pressure liquid chromatography
AU2009347432B2 (en) 2009-06-03 2015-01-29 Agilent Technologies, Inc. Sample injector with metering device balancing pressure differences in an intermediate valve state
EP2445602A4 (en) * 2009-06-26 2013-11-13 Waters Technologies Corp CHROMATOGRAPHY DEVICE WITH INTEGRATED CORE
US8541493B2 (en) * 2010-02-19 2013-09-24 Arch Chemicals, Inc. Synthesis of zinc acrylate copolymer from acid functional copolymer, zinc pyrithione, and copper compound
WO2011106642A1 (en) * 2010-02-26 2011-09-01 Perkin Elmer Health Sciences, Inc. Fluid chromatography injectors and injector inserts
CN203244808U (zh) * 2010-02-26 2013-10-23 珀金埃尔默健康科技有限公司 喷射组件、喷射组件插入件、火焰检测器以及包括其的套件
US8569070B2 (en) 2010-07-16 2013-10-29 Idex Health & Science Llc Connection assembly for ultra high pressure liquid chromatography
EP3181208B1 (en) 2010-08-10 2022-06-15 Idex Health&Science LLC Biocompatible tubing for liquid chromatography systems
US8931808B2 (en) 2011-03-01 2015-01-13 Idex Health & Science Llc High pressure fitting with self-releasing ferrule
US9188569B2 (en) 2011-03-01 2015-11-17 Idex Health & Science Llc High pressure fitting with self-releasing ferrule
EP2626697B1 (en) 2012-02-07 2018-10-31 King Saud University Liquid chromatography device
US9791080B2 (en) 2012-03-12 2017-10-17 Idex Health & Science Llc Microfluidic interconnect
WO2014074499A1 (en) 2012-11-06 2014-05-15 Idex Health & Science Llc Torque limiting tool and methods
TWI579553B (zh) * 2013-11-24 2017-04-21 中央研究院 以紫外光－可見光檢測之高效能液相層析設備及方法
US10422452B2 (en) 2014-04-16 2019-09-24 IDEX Health & Sciences LLC High pressure fluidic connection assemblies
US11275063B2 (en) 2014-05-20 2022-03-15 Idex Health & Science Llc Frits for chromatography
EP3209920B1 (en) 2014-10-23 2021-04-21 Idex Health & Science LLC Face-sealing fluidic connection system
US10012620B1 (en) 2015-04-07 2018-07-03 Sielc Technologies Corporation Chromatography sample introduction device
US10371672B1 (en) 2015-04-15 2019-08-06 Yury Zelechonok Integrated chromatography column injector detector device
DE202016100451U1 (de) 2015-06-25 2016-02-16 Dionex Softron Gmbh Probengeber für die Flüssigkeitschromatographie, insbesondere für die Hochleistungsflüssigkeitschromatographie
US10520477B2 (en) 2016-12-09 2019-12-31 Idex Health & Science Llc High pressure valve with multi-piece stator assembly
US10384151B2 (en) 2016-12-09 2019-08-20 Idex Health & Science Llc High pressure valve with two-piece stator assembly
US11054054B2 (en) 2016-12-09 2021-07-06 Idex Health & Science Llc High pressure valve with multi-piece stator assembly
EP3561504B1 (en) 2018-04-25 2023-01-04 Idex Health & Science LLC High pressure valve with multi-piece stator assembly
US11085904B2 (en) 2018-09-28 2021-08-10 Idex Health And Science Llc Column having a compression-limited assembly

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0933502A (ja) * 1995-07-18 1997-02-07 Shimadzu Corp ガスクロマトグラフ装置

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US328910A (en) 1885-10-20 Corn and cane harvester
US3186234A (en) 1961-09-12 1965-06-01 Beckman Instruments Inc Sampling valve
US3621263A (en) * 1970-04-13 1971-11-16 Warren E Gilson Volumetric fraction supply apparatus
EP0327658B1 (en) 1988-02-11 1991-10-23 Hewlett-Packard GmbH Sample injector for a liquid chromatograph
US5795788A (en) 1993-06-05 1998-08-18 Glaxo Group Limited Liquid flow management means
DE4447333A1 (de) * 1994-12-31 1996-07-04 Bayer Ernst Prof Dr Gradienten - Injektions - Modul für Kapillar-HPLC, Kapillarelektrophorese und Elektrochromatographie
EP0990899B1 (en) 1998-05-25 2005-11-23 Agilent Technologies, Inc. (a Delaware corporation) Sample injector for a high-pressure liquid chromatograph
US6387234B1 (en) * 1998-08-31 2002-05-14 Iowa State University Research Foundation, Inc. Integrated multiplexed capillary electrophoresis system
US6190550B1 (en) * 1999-09-30 2001-02-20 Cohesive Technologies, Inc. Monitoring high performance liquid chromatography
US6290909B1 (en) 2000-04-13 2001-09-18 Sandia Corporation Sample injector for high pressure liquid chromatography
US6557575B1 (en) 2001-11-19 2003-05-06 Waters Investments Limited Fluid flow control freeze/thaw valve for narrow bore capillaries or microfluidic devices
WO2004025153A2 (en) 2002-09-16 2004-03-25 Waters Investments Limited Freeze-thaw valve limiting cryogenic usage

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0933502A (ja) * 1995-07-18 1997-02-07 Shimadzu Corp ガスクロマトグラフ装置

Also Published As

Publication number Publication date
GB2426216A (en) 2006-11-22
US20070283746A1 (en) 2007-12-13
GB2426216B (en) 2010-05-26
JP2007519007A (ja) 2007-07-12
DE112005000128T5 (de) 2007-05-03
GB0615960D0 (en) 2006-09-27
US8173070B2 (en) 2012-05-08
WO2005071396A1 (en) 2005-08-04
GB0615976D0 (en) 2006-09-20
DE112005000128B4 (de) 2024-12-19

Similar Documents

Publication Publication Date Title
JP4782701B2 (ja) 液体クロマトグラフィーのための試料注入システム
EP2362214B1 (en) Sample injection device, sample injection method, and liquid chromatography device
JP2007519007A5 (enExample)
CN104833745B (zh) 将样品加入液相色谱设备的分析支管的方法
JPH11511555A (ja) 分離媒質の置換手段を有する電気泳動システム
CN103448374B (zh) 流路内气泡减少装置以及方法、液体供给装置及色谱装置
JP4121455B2 (ja) Ｎｍｒフロープローブへのサンプル移送およびｎｍｒフロープローブからのサンプル移送を利用する装置および方法
US20060045810A1 (en) Sample injector for liquid analysis
GB2320569A (en) Preparing samples for gas chromatography
EP0563865A2 (en) Method and apparatus for analyzing hemoglobins and solution for suppressing column deterioration for use therein
US20050194298A1 (en) Pressurized fluid sample injector and method of injecting fluid samples
US20190314809A1 (en) Bubble eliminating structure, bubble eliminating method, and agitating method using the same
CA1303949C (en) Sample handling system
US20050129539A1 (en) Equipment and method for feeding liquid gradient in nano/micro liquid chromatography
AU596906B2 (en) Gas bubble generator
JP4150162B2 (ja) コンテナを充填する方法、装置及びシステム
US20030133843A1 (en) Set comprising a pipette and a cartridge, as well as a method for applying a sample to the cartridge and an analytical method
AU770513B2 (en) Device and method for treating a sample by overpressured layer chromatography a stationary phase, under controlled forced flow
US20100059549A1 (en) Apparatus and method for dosing of liquids in gas filled spaces
AU697318B2 (en) Sampling bottle arrangement
JP2001133445A (ja) 液体クロマトグラフ
JPH10339267A (ja) 送液機構、並びに該送液機構を用いたサンプリング機構及びカラムクロマトグラフ装置
US20070110628A1 (en) Apparatus and method for dispensing fractions of an analyte solution
WO2022112911A1 (en) Testing a sampling unit fluidically coupled to a source
WO2004081540A2 (en) Device for automatic and programmed sampling and dosingof liquid mediums

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20071225

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20071225

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A712

Effective date: 20090721

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100921

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20101215

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20101222

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20110628

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20110707

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20140715

Year of fee payment: 3

R150 Certificate of patent or registration of utility model

Ref document number: 4782701

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees