JP4782688B2 - 医薬品としての架橋環構造 - Google Patents
医薬品としての架橋環構造 Download PDFInfo
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- JP4782688B2 JP4782688B2 JP2006535596A JP2006535596A JP4782688B2 JP 4782688 B2 JP4782688 B2 JP 4782688B2 JP 2006535596 A JP2006535596 A JP 2006535596A JP 2006535596 A JP2006535596 A JP 2006535596A JP 4782688 B2 JP4782688 B2 JP 4782688B2
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- C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
- C07C39/15—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with all hydroxy groups on non-condensed rings, e.g. phenylphenol
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- C07C39/21—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing only six-membered aromatic rings as cyclic parts with unsaturation outside the rings with at least one hydroxy group on a non-condensed ring
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- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
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- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
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| US51145703P | 2003-10-14 | 2003-10-14 | |
| US60/511,457 | 2003-10-14 | ||
| PCT/US2004/033666 WO2005037755A2 (en) | 2003-10-14 | 2004-10-13 | Bridged ring structures as pharmaceutical agents |
Publications (3)
| Publication Number | Publication Date |
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| JP2007509847A JP2007509847A (ja) | 2007-04-19 |
| JP2007509847A5 JP2007509847A5 (https=) | 2007-11-29 |
| JP4782688B2 true JP4782688B2 (ja) | 2011-09-28 |
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| DE (1) | DE602004025261D1 (https=) |
| WO (1) | WO2005037755A2 (https=) |
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| SI1511740T1 (sl) * | 2002-05-29 | 2009-12-31 | Lilly Co Eli | Modulatorji vitamin d receptorja tipa fenil-tiofen |
| ES2291981T3 (es) * | 2003-11-20 | 2008-03-01 | Eli Lilly And Company | Moduladores del receptor de la vitamina d. |
| CA2544857A1 (en) * | 2003-11-20 | 2005-06-09 | Eli Lilly And Company | Vitamin d receptor modulators |
| TW200600494A (en) * | 2004-03-08 | 2006-01-01 | Chugai Pharmaceutical Co Ltd | Bisphenyl compounds useful as vitamin d3 receptor agonists |
| US7825265B2 (en) | 2004-05-04 | 2010-11-02 | Acadia Pharmaceuticals Inc. | Compounds with activity at estrogen receptors |
| TW200716536A (en) | 2005-06-09 | 2007-05-01 | Chugai Pharmaceutical Co Ltd | Vitamin D compounds |
| WO2009114540A2 (en) * | 2008-03-10 | 2009-09-17 | Wisconsin Alumni Research Foundation | Vitamin d compounds and methods for reducing ocular hypertension (oht) |
| WO2010082837A1 (en) * | 2009-01-16 | 2010-07-22 | Jan Anne Lyftogt | Medicament for the treatment of pain and inflammation |
| CA2981549A1 (en) | 2009-01-27 | 2010-08-05 | Berg Llc | Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy |
| CN106265695B (zh) | 2009-08-14 | 2021-05-07 | 博格有限责任公司 | 用于治疗脱发的维生素d3及其类似物 |
| JP5375502B2 (ja) * | 2009-10-06 | 2013-12-25 | 信越化学工業株式会社 | アルコール性水酸基含有化合物及びその製造方法 |
| CN112156097A (zh) | 2013-05-29 | 2021-01-01 | 博格有限责任公司 | 使用维生素d预防或减轻化疗诱发的脱发 |
| US10751315B2 (en) | 2017-08-29 | 2020-08-25 | National Jewish Health | Methods and compositions for treating infection and inflammation with selenocyanate |
Citations (2)
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| JP2002523388A (ja) * | 1998-08-24 | 2002-07-30 | リガンド・ファーマシューティカルズ・インコーポレイテッド | ビタミンd3模擬体 |
| JP2006507344A (ja) * | 2002-11-22 | 2006-03-02 | イーライ・リリー・アンド・カンパニー | ビタミンdレセプターモジュレーター |
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| DE1543908A1 (de) | 1966-07-05 | 1970-01-02 | Stecker Chemicals Inc | Verfahren zur Herstellung von keimtoetend wirkenden,durch zwei Fluormethylgruppen substituierten Methylen-bisphenolen |
| JPS4931651A (https=) | 1972-07-20 | 1974-03-22 | ||
| US4717760A (en) * | 1986-07-10 | 1988-01-05 | The Dow Chemical Company | Fluorinated tris-epoxides based on triphenyl methane |
| EP0285160B1 (en) * | 1987-04-03 | 1993-12-08 | Daikin Industries, Limited | Fluorine-containing aromatic compound, process for preparing the same and use thereof |
| DE3879113D1 (de) | 1987-11-24 | 1993-04-15 | Hoechst Ag | Teilfluorierte carbonsaeuren sowie derivate davon, verfahren zu ihrer herstellung und verwendung. |
| DE4001932A1 (de) | 1990-01-24 | 1991-07-25 | Bayer Ag | 1,1-bicyclo-substituierte fluorhaltige cyclopentane und verfahren zu deren herstellung |
| JPH03255067A (ja) | 1990-03-05 | 1991-11-13 | Nitto Denko Corp | 含フッ素ビスマレイミド及びその製造方法 |
| US5210353A (en) * | 1990-11-30 | 1993-05-11 | Amoco Corporation | Aromatic transformation process |
| JP2784882B2 (ja) * | 1994-04-28 | 1998-08-06 | 第一工業製薬株式会社 | 粉末状高融点2,2−ビス[4′−(2″,3″−ジブロモプロポキシ)−3′,5′−ジブロモフェニル]プロパンの製造方法 |
| EP1535610A4 (en) | 2002-06-10 | 2008-12-31 | Inst Med Molecular Design Inc | THERAPEUTIC CANCER |
| US20060035944A1 (en) * | 2002-06-11 | 2006-02-16 | Susumu Muto | Remedies for neurodegenerative diseases |
| EP1587906A2 (en) | 2003-01-10 | 2005-10-26 | Eli Lilly And Company | Vesicant treatment with phenyl-phenyl type vitamin d receptor modulators |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002523388A (ja) * | 1998-08-24 | 2002-07-30 | リガンド・ファーマシューティカルズ・インコーポレイテッド | ビタミンd3模擬体 |
| JP2006507344A (ja) * | 2002-11-22 | 2006-03-02 | イーライ・リリー・アンド・カンパニー | ビタミンdレセプターモジュレーター |
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| CA2542650A1 (en) | 2005-04-28 |
| JP2007509847A (ja) | 2007-04-19 |
| US7863298B2 (en) | 2011-01-04 |
| WO2005037755A3 (en) | 2005-08-18 |
| WO2005037755A2 (en) | 2005-04-28 |
| AU2004282162B2 (en) | 2012-01-19 |
| EP1675812A2 (en) | 2006-07-05 |
| US20070225377A1 (en) | 2007-09-27 |
| AU2004282162A1 (en) | 2005-04-28 |
| EP1675812B1 (en) | 2010-01-20 |
| DE602004025261D1 (de) | 2010-03-11 |
| CA2542650C (en) | 2013-04-23 |
| ATE455749T1 (de) | 2010-02-15 |
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