JP4778230B2 - アシルアミノ−置換複素芳香族化合物および医薬としてのそれらの使用 - Google Patents

アシルアミノ−置換複素芳香族化合物および医薬としてのそれらの使用 Download PDF

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JP4778230B2
JP4778230B2 JP2004526764A JP2004526764A JP4778230B2 JP 4778230 B2 JP4778230 B2 JP 4778230B2 JP 2004526764 A JP2004526764 A JP 2004526764A JP 2004526764 A JP2004526764 A JP 2004526764A JP 4778230 B2 JP4778230 B2 JP 4778230B2
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alkyl
group
phenyl
heteroaryl
alkoxy
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JP2005538123A5 (fr
JP2005538123A (ja
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ハルトムート・シュトローベル
パウルス・ヴォールファルト
ペーター・ベロウ
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サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング
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    • C07—ORGANIC CHEMISTRY
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    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
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    • A61P9/08—Vasodilators for multiple indications
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    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
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    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
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    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
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  • Hospice & Palliative Care (AREA)
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  • Neurology (AREA)
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  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2004526764A 2002-08-07 2003-07-24 アシルアミノ−置換複素芳香族化合物および医薬としてのそれらの使用 Expired - Fee Related JP4778230B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02017585A EP1388341A1 (fr) 2002-08-07 2002-08-07 Dérivés héteroaromatiques acylamino substitués et leur utilisation en tant que medicaments
EP02017585.7 2002-08-07
PCT/EP2003/008102 WO2004014369A1 (fr) 2002-08-07 2003-07-24 Composes heteroaromatiques acylamino-substitues et leur utilisation en tant que produits pharmaceutiques

Publications (3)

Publication Number Publication Date
JP2005538123A JP2005538123A (ja) 2005-12-15
JP2005538123A5 JP2005538123A5 (fr) 2006-09-07
JP4778230B2 true JP4778230B2 (ja) 2011-09-21

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Country Status (10)

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EP (2) EP1388341A1 (fr)
JP (1) JP4778230B2 (fr)
AT (1) ATE388702T1 (fr)
AU (1) AU2003260325A1 (fr)
BR (1) BR0313294A (fr)
CA (1) CA2494298A1 (fr)
DE (1) DE60319711T2 (fr)
IL (1) IL166493A0 (fr)
MX (1) MXPA05000697A (fr)
WO (1) WO2004014369A1 (fr)

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AU2003260325A1 (en) 2004-02-25
BR0313294A (pt) 2005-07-12
DE60319711D1 (de) 2008-04-24
WO2004014369A1 (fr) 2004-02-19
EP1388341A1 (fr) 2004-02-11
JP2005538123A (ja) 2005-12-15
ATE388702T1 (de) 2008-03-15
EP1534275B1 (fr) 2008-03-12
MXPA05000697A (es) 2005-04-08
CA2494298A1 (fr) 2004-02-19
EP1534275A1 (fr) 2005-06-01
DE60319711T2 (de) 2009-04-02
IL166493A0 (en) 2006-01-15

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